• Title/Summary/Keyword: antiseptic

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Antimicrobial activity against Propionibacterium acnes bacteria of Smilacis glabrae Rhizoma extracts (토복령 추출물의 여드름 균에 대한 항균활성)

  • Park, Jang-Soon;Kwon, Hye-Jin
    • Journal of the Korea Convergence Society
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    • v.8 no.12
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    • pp.425-430
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    • 2017
  • This study was conducted to measure the antimicrobial activity and antiseptic effect of Smilax china root extracts against Propionibacterium acnes and to develop natural antimicrobial extracts as an alternative for synthetic preservatives, which have recently been controversial. Extracts were obtained from dried Korean Smilax china root at room temperature using two solvents, distilled water and 95% EeOH, separately. According to the results of this study, the antimicrobial effect of Propionibacterium acnes 3314 and Propionibacterium acnes 3320 against Propionibacterium acnes was outstanding. In particular, the clear zone of the extract using distilled water showed the highest activity with 16.61 mm. As for the result of the collection of contaminated skin sample, the clear zone was 24.48 mm. This indicates that Smilax china root extracts show a high activity against skin flora as well as a high antimicrobial activity against Propionibacterium acnes. In conclusion, it is confirmed that Smilax china root extracts can be used as raw materials for cosmetics that have antimicrobial activity and antiseptic effect, and it is expected that Smilax china root extracts will be used as basic materials for the development of future natural preservatives.

Clinical Study Comparing the Skin Antiseptics of Povidone-iodine and Chlorhexidine-ethanol on Port Site (투관침 부위에 적용하는 포비돈 아이오딘과 클로르헥시딘-에탄올의 소독제 효과 연구)

  • Kang, Min Jung
    • Journal of Convergence for Information Technology
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    • v.10 no.10
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    • pp.80-87
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    • 2020
  • The purpose of this study was to compare in antiseptic effect between povidone-iodine and chlorhexidine-ethanol for laparoscopic cholecystectomy on the port site. A total of 46 patients admitted to surgery at one university hospital in Seoul were included in the study. A study group was randomly assigned using a random number table. The antiseptic effect was evaluated and compared to povidone-iodine and chlorhexidine-ethanol by using a culture and identification of bacteria, measurement of the number of bacteria (CFU/ml) and incidence of surgical site infection. Our results show that povidone-iodine and chlorhexidine-ethanol have no statistically significant difference in the incidence rate of bacteria after 3 minutes of disinfection and before removal of the trocar and in the number of bacteria and the incidence of surgical site infection. Thus, in order to select an efficient and appropriate skin antiseptics, we suggest that it is necessary to consider not only the disinfectant effect but also cost and convenience. In this research, our results about effect and usage of skin antiseptics can be used as basic data and educational resource, and this is expected to improve comprehension of skin antiseptics.

The efficiency of topical anesthetics as antimicrobial agents: A review of use in dentistry

  • Kaewjiaranai, Thanawat;Srisatjaluk, Ratchapin Laovanitch;Sakdajeyont, Watus;Pairuchvej, Verasak;Wongsirichat, Natthamet
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.18 no.4
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    • pp.223-233
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    • 2018
  • Topical anesthetics are commonly used in oral & maxillofacial surgery to control pain in the oral cavity mucosa before local anesthetic injection. These anesthetic agents come in many forms, developed for different usages, to minimize adverse reactions, and for optimal anesthetic efficiency. Earlier studies have revealed that these agents may also limit the growth of microorganisms in the area of anesthetic application. Many topical anesthetic agents show different levels of antimicrobial activity against various bacterial strains and Candida. The dosage of local anesthetic agent used in some clinical preparations is too low to show a significant effect on microbial activity. Efficiency of antimicrobial activity depends on the local anesthetic agent's properties of diffusion within the bloodstream and binding efficiency with cytoplasmic membrane, which is followed by disruption of the bacterial cell membrane. The antimicrobial properties of these agents may extend their usage in patients to both control pain and infection. To develop the topical local anesthetic optimal usage and antimicrobial effect, a collaborating antiseptic agent may be used to benefit the local anesthetic. However, more research is required regarding minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of topical local anesthetic agents with drug interaction between anesthetics and antiseptic agents.

Salivary Bacterial Counts on Application Time of Oral Antiseptic Agents and Mechanical Irrigation (구강소독제의 적용 시간 및 기계적 세척 여부에 따른 타액 내 세균 수의 감소 효과)

  • Lim, Hyoung-Sup;Kim, Jae-Jin;Kim, Mija;Kim, Hak Kyun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.35 no.3
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    • pp.155-160
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    • 2013
  • Purpose: The purpose of this study is to establish the acceptable intraoral application time of antiseptic agents and evaluate the effect of mechanical irrigation. Methods: A total of 80 subjects were selected for this study. Saliva secreted at the resting state was taken. The subjects were divided into 8 experimental groups, and kept 10% povidone-iodine (PVI) or 0.2% chlorhexidine gluconate (CHX) for 20 or 40 seconds in their oral cavity with/without irrigation of the oral cavity with sterilized normal saline, respectively. Then, the saliva was taken and diluted with phosphate buffered saline and then plated onto 5% sheep blood agar plates, which were incubated. Colony forming unit (CFU) was measured for the salivary bacterial counts. Results: After application of PVI and CHX, all the experimental groups showed statistically significant decrease in CFU (P<0.01). Group 2 (PVI, 40 s) showed more significant reduction rate in CFU than group 4 (CHX, 40 s; P<0.01). Group 6 (PVI, 40 s, irrigated) showed more significant reduction rate than group 2 (PVI, 40 s; P<0.01). Group 2 (PVI, 40 s) showed more significant reduction rate than group 1 (PVI, 20 s; P<0.01). Conclusion: Application of PVI for 40 seconds and mechanical irrigation with sterilized normal saline showed the best result among the 8 groups in terms of the reduction rate of salivary bacterial counts.

Evaluation of water holding property for applying a cosmetic moisturizer from oil palm trunk CNF (오일 팜 수간 유래 CNF (cellulose nanofibrils)의 화장품 보습제 적용을 위한 보습력 평가)

  • Song, Woo-Yong;Shin, Soo-Jeong
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.48 no.2
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    • pp.91-98
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    • 2016
  • Cellulose nanofibrils (CNF) was made from oil palm trunk (OPT) with soda-anthraquinone pulping, chlorine dioxide bleaching, carboxymethylation, followed by mechanical grinding. Size of this CNF was 16-40 nm of width confirmed by TEM. To evaluate CNF from OPT as cosmetics raw materials for moisturizing component, water holding properties was compared with hyaluronic acid and collagen. CNF from OPT had better water holding property than collagen or hyaluronic acid whether phenoxyethanol was added as antiseptic or without additive.

The Practical Application of Folk Remedies to the Contents of Medicine (의학콘텐츠로서의 단방요법 활용화 방안)

  • Lee, Sun-A;Chough, Won-Joon
    • Korean Journal of Oriental Medicine
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    • v.13 no.1 s.19
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    • pp.63-68
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    • 2007
  • Folk Remedies symbolize the medical art of the common people, and contain their special emotion and colloquial expressions. They are medical treatments in which the medical history and the tradition and the soul of a people are incorporated. They are handed down in various ways. This study introduces some of folk remedies. For example, powder of tigers' bones heals neuralgia. Rice wine brewing up with ginger is effective in a cold. Water boiling with safflower does good in neuralgia. Pasting herba houttuyniae takes effect in skin disease. To Decoct and drink old hardy orange is effective in urticaria. Water boiling with fructus corni alleviates a fever. Camellia oil or rhizoma cnidii or iris is used for the extermination of vermin and the antiseptic. In the end, the practical application of these remedies to the resources of industry and education will be discussed.

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Disinfection Efficacy of an Ultraviolet Light on Film Cassettes for Preventive of the Nosocomial Infection (병원감염 예방을 위한 Film Cassette의 자외선 소독 효과)

  • Kweon, Dae-Cheol;Jeon, Yong-Woong;Cho, Am
    • Journal of radiological science and technology
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    • v.24 no.1
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    • pp.27-32
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    • 2001
  • The bacteria infection on film cassette contact surface was examined at the diagnostic radiology department of the S. hospital. The objective of this study was to assess the contamination level on film cassette contact surface as a predictor of patient prevention from nosocomial infection and for improvement of the hospital environment. The laboratory result was identified non-pathologic bacterial in the five different cassette size of the contact surface. Film cassettes were exposed to ultraviolet light for 1, 2 and 3 minutes. Ultraviolet light disinfection is proven suitable for bacteria. The study concludes that presence of a bacterial infection will prevent a using antiseptic technique on film cassette contact surface. In addition education of nosocomial infection for radiographers will be required. In conclusion, ultraviolet is considered effective to irradate bacteria. Additionally, two minutes are required to sterilize film cassettes.

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The Study on the perilla oil for the conservation of wooden cultural properties (목조문화재 보존 및 단청에 이용하는 들기름에 관한 연구)

  • Kim, Soon-Kwan;Hong, Jung-Ki
    • 보존과학연구
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    • s.21
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    • pp.273-291
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    • 2000
  • The perilla oil is painted to the wooden cultural properties of protection of wood and pigment. But that is happened to discolor and gather mold because of the long drying time. So we were put to the test for the improvement of this matter. The result is follows;1. The perilla oil, do not parched domestic Perilla japonica, add to the Japanese acid clay, later passing through the filter paper that the pore size is less than $7\mum$ 2. If the perilla oil add to the antiseptic of Thiazole origin, the mold is suppressed.3. In the painting of perilla oil, the existing Dan-chung paints one time (Luster generation in the more than two times) and the non-existing Dan-Chung paints two times.

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A Study on the Sterilizer Using the Microwave (마이크로파를 이용한 살균장치에 관한 연구)

  • 김행길;이화용
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.4 no.2
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    • pp.479-485
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    • 2000
  • In this study, the chamber size was designed and manufactured so as to make a resonance with microwaves in sterilizing moisture-contained food by making good use of microwaves. When the green-pea jelly which was made and sterilized for experimental usage with no addition of an antiseptic was left in the room temperature for 1 minute, 2 minutes or 3 minutes respectively, resulted in delaying more greatly the procession of change in quality of food for almost 7 to 15 days than in unsterilized food. As a result of experiment conducted above, it is considered to produce good results of decreasing the resource waste and environmental pollution, by lengthening the period of preservation and circulation of food.

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Anti-inflammatory, antinociceptive and diuretic activities of Trema orientalis Linn

  • Uddin, Sarder Nasir;Yesmin, Mst Nazma;Pramanik, M.K.;Akond, Ma
    • Advances in Traditional Medicine
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    • v.9 no.4
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    • pp.320-325
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    • 2009
  • The pharmacological interest coupled with traditional uses (antidiarrhoeal, antiseptic, analgesic etc) prompted us to test for anti-inflammatory, antinociceptive and diuretic activitities of Trema (T.) orientalis Linn. The crude methanolic leaves extract of T. orientalis was investigated for its possible anti-inflammatory activities using carrageenin induced rat paw edema model and cotton pellet implantation method in mice. Then the extract analyzed for its antinociceptive activities by acetic acid induced writhing model in mice. The extract possessed significant anti-inflammatory activity in both models at the doses of 200 and 400 mg/kg body weight of mice. Moreover, the extract showed significantly reduced the number of acetic acid-induced abdominal constriction in mice of 200 and 400 mg/kg body weight. The extract also showed positive diuretic activity in albino mice.