• Title/Summary/Keyword: anti-sigma

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Redox-Dependent Modulation of RsrA, an Anti-Sigma Factor Regulating Thioredoxin Operons in Streptomyces coelicolor

  • Bae, Jae-Bum;Park, Joo-Hong;Roe, Jung-Hye
    • Proceedings of the Korean Biophysical Society Conference
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    • 2002.06b
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    • pp.54-54
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    • 2002
  • $\sigma$$\^$R/ is a sigma factor responsible for inducing the thioredoxin system in response to oxidative stress in Streptomyces coelicolor. RsrA, an anti-sigma factor, specifically binds to $\sigma$$\^$R/ and inhibits $\sigma$$\^$R/-directed transcription under reducing conditions. Exposure to H$_2$O$_2$ or thiol-specific oxidant diamide dissociates $\sigma$$\^$R/-RsrA complex. The redox-dependent regulation of $\sigma$$\^$R/-RsrA binding has been reported to involve thiol-disulfide exchange in RsrA, which contains 7 cysteines in 105 amino acid residues.(omitted)

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MO Studies of Configuration and Conformation (XV). Through-Space and Through-Bond Interactions In Ethylene Diamine (배치와 형태에 관한 분자궤도론적 연구 (제15보). 에틸렌 디아민의 Through-Space 및 Through-Bond 상호작용)

  • Ikchoon Lee;Chang Kook Sohn;Chang Hyun Song
    • Journal of the Korean Chemical Society
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    • v.26 no.2
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    • pp.65-72
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    • 1982
  • STO-3G level computations were performed on n-propylamine, n-propylamine radical and cis-and trans-ethylene diamines in order to investigate structural contributions of (n${\pi}$/m) and (n-${\sigma}^*$) structures to the energy variations accompanying the conformational changes. It was found that (5${\pi}$/5) and (4${\pi}$/4) structures had attractive and repulsive nonbonded interactions, respectively, which were approximately additive. anti(n-${\sigma}^*$) structures had more stabilzing hyperconjugative interactions than syn(n-${\sigma}^*$) structures, but due to the large internuclear repulsion the net effect was destabilizing inthe former in contrast with the net stabilizing contribution in the latter. Moreover it was found that the stabilizing ${\pi}$-nonbond structure, (5${\pi}$/5) was always cooperatively reinforced by the more stabilizing anti(n-${\sigma}^*$) interaction, whereas the destabilizing (4${\pi}$/4) structure was accompanied by the less stabilizing syn(n-${\sigma}^*$) interaction. This type of cooperativity was found general through-bond interaction of the terminal lone pair lobes split the energy levels into two, $n_+ = \frac{1}{\sqrt{2}}(n_1 + n_2)$ and $n_- = \frac{1}{\sqrt{2}}(n_1 - n_2)$, the latter being the lower level, which can be shown using simple overlap patterns of the two lobes with a common vicinal ${\sigma}^*$ orbital.

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A NOTE ON INDECOMPOSABLE 4-MANIFOLDS

  • Cho, Yong-Seung;Hong, Yoon-Hi
    • Bulletin of the Korean Mathematical Society
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    • v.42 no.4
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    • pp.817-828
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    • 2005
  • In this note we show that there is an anti-symplectic involution $\sigma\;:\;X\;\to\;X$ on a simply-connected, closed, non-Kahler and symplectic 4-manifold X with a disjoint union of Riemann surfaces ${\amalg}^n_{i=1}{\Sigma}_i,\;n\;{\ge}\;2$ as a fixed point set. Also we show that its quotient X/$\sigma$ is homeomorphic to $\mathbb{CP}^2{\sharp}r\mathbb{CP}^2$ but not diffeomorphic to $\mathbb{CP}^2{\sharp}r\mathbb{CP}^2,\;r\;=\;b_2^-(X/{\sigma})$.

Mixed CT/DT Cascaded Sigma-Delta Modulator

  • Lee, Kye-Shin
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.9 no.4
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    • pp.233-239
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    • 2009
  • A mixed CT/DT 2-1 cascaded ${\Sigma\Delta}M$ which includes a first stage CT ${\Sigma\Delta}M$ and a second stage mismatch insensitive two-channel time-interleaved DT ${\Sigma\Delta}M$ is proposed. With this approach, the advantages of both CT and DT ${\Sigma\Delta}Ms$ including high speed operation, inherent anti-aliasing filter, and good coefficient matching can be achieved. The two-channel time-interleaved ${\Sigma\Delta}M$ used in the second stage alleviates the speed constraints of the DT ${\Sigma\Delta}M$, whereas enables better matching between the analog and digital filter coefficients compared to CT ${\Sigma\Delta}Ms$.

SOME RESULTS ON ENDOMORPHISMS OF PRIME RING WHICH ARE $(\sigma,\tau)$-DERIVATION

  • Golbasi, Oznur;Aydin, Neset
    • East Asian mathematical journal
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    • v.18 no.2
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    • pp.195-203
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    • 2002
  • Let R be a prime ring with characteristic not two and U is a nonzero left ideal of R which contains no nonzero nilpotent right ideal as a ring. For a $(\sigma,\tau)$-derivation d : R$\rightarrow$R, we prove the following results: (1) If d is an endomorphism on R then d=0. (2) If d is an anti-endomorphism on R then d=0. (3) If d(xy)=d(yx), for all x, y$\in$R then R is commutative. (4) If d is an homomorphism or anti-homomorphism on U then d=0.

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The Putative Sigma (YlaC) and Anti-Sigma Factors (YlaD) from Bacillus subtilis

  • Ryu, Han-Bong;Tsogbadrakh. M;Sa-Ouk kang
    • Proceedings of the Korean Biophysical Society Conference
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    • 2001.06a
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    • pp.51-51
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    • 2001
  • Two open reading frame designated as ylaC and ylaD in the Bacillus subtilis genomic sequencing project, were cloned using pRB374 vector which is shuttle vector in E. coli and B. subtilis. YlaC and YlaD have the sequence homology to SigX and SigW to YbbM, respectively, which are known to be ECF sigmaand anti-sigma factor, respectively.(omitted)

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Mechanism of Redox- and Metal-dependent Modulation of RsrA, an Anti-sigma Factor for Redox-dependent Regulation of Thioredoxin Operons in Streptomyces coelicolor

  • Bae, Jae-Bum;Park, Ju-Hong;Roe, Jung-Hye
    • Proceedings of the Korean Biophysical Society Conference
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    • 2001.06a
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    • pp.63-63
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    • 2001
  • SigR ($\sigma$$\^$R/) is a sigma factor responsible for inducing the thioredoxin system in response to oxidative stress in Streptomyces coelicolor. RsrA specifically binds to $\sigma$$\^$R/ and inhibits $\sigma$$\^$R/-directed transcription under reducing conditions. Exposure to H$_2$O$_2$ or thiol-specific oxidant diamide dissociates $\sigma$$\^$R/-RsrA complex. RsrA contains 7 cysteine residues in 105 total amino acid residues.(omitted)

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A Quantitative Analysis of $\pi$-Nobonded and Through-Bond Interactions in n-Butane, n-Buthyl Radical and Tetramethylene Diradical$^1$

  • Lee Ikchoon;Cheun Young Gu
    • Bulletin of the Korean Chemical Society
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    • v.3 no.1
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    • pp.1-4
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    • 1982
  • A quantitative treatment of ${\pi}$-nonbonded and $n-{\sigma}^{\ast}$ interactions and through-bond coupling effect was attempted using n-butane, n-butyl radical, and tetramethylene diradical. Results of STO-3G level calculations showed that: (1) conformational preferences can be predicted quantitatively based solely on the additive effect of ${\pi}$-nonbonded and $n-{\sigma}^{\ast}$ interactions, the predominant effect being the ${\pi}$-nonbonded interactions, (2) $(n-{\sigma}^{\ast})_{anti}$ is destabilizing whereas $(n-{\sigma}^{\ast})_{syn}$ is weakly stabilizing, which are contrary to what we expect from the normal $n-{\sigma}^{\ast}$ interaction, (3) througb-bond coupling of the two radical lobes is destabilizing for the triplet but stabilizing for the singlet tetramethylene diradical.