• Title/Summary/Keyword: almost stability

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The Influence of Protecting Groups on the β-Sheet Structure Stability of Protected Peptides

  • 이진식;이동진
    • Bulletin of the Korean Chemical Society
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    • v.16 no.7
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    • pp.591-594
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    • 1995
  • The influence of protecting groups on the β-sheet-structure-stability of protected peptides was studied in organic solvents. α-amino groups, carboxyl groups and side chain functional groups of model peptides were protected by suitable groups commonly used in peptide synthesis. The difference of the solubilities of model peptides was investigated by the solvent-titration method by using IR absorption spectra. The β-sheet structure of model peptide in CH2Cl2 was easily disrupted by increasing the amounts of DMSO. The β-sheet-structure-stabilizing potentials of each protecting group showed similar behaviors except Npys, Mts and Z2. The result exhibits that the < SPβ > values of protected peptides are almost independent of the kinds of their protecting groups.

On the cyclic change in the dynamics of the IBR-2M pulsed reactor

  • Yu.N. Pepelyshev;Sumkhuu Davaasuren
    • Nuclear Engineering and Technology
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    • v.55 no.5
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    • pp.1665-1670
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    • 2023
  • It is shown that in the IBR-2M reactor by the end of the reactor cycle, changes in dynamics are observed associated with a strong weakening of the fast power feedback (PF), as a result of which the reactor becomes oscillatorily unstable. After each week of zero-power operation the negative changes in reactor dynamics disappear and the stability of the reactor is restored. Thus, the reactor undergoes cyclic changes in the oscillatory instability. The correlation between of a fast PF and a slow PF is experimentally observed, which makes it possible to almost completely eliminate the cyclic component of instability by changing the control mode of rods of the control system.

ALMOST QUADRATIC LIE *-DERIVATIONS ON CONVEX MODULAR *-ALGEBRAS

  • Ick-Soon Chang;Hark-Mahn Kim
    • Nonlinear Functional Analysis and Applications
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    • v.28 no.4
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    • pp.887-902
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    • 2023
  • In this article, we investigate an approximate quadratic Lie *-derivation of a quadratic functional equation f(ax + by) + abf(x - y) = (a + b)(af(x) + bf(y)), where ab ≠ 0, a, b ∈ ℕ, associated with the identity f([x, y]) = [f(x), y2] + [x2, f(y)] on a 𝜌-complete convex modular *-algebra χ𝜌 by using ∆2-condition via convex modular 𝜌.

Structural Stability of Bacteriorhodopsin Solubilized by Triton X-100

  • Sasaki, Takanori;Sonoyama, Masashi;Mukai, Yuri;Nakazawa, Chieko;Mitaku, Shigeki
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.293-295
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    • 2002
  • The structural stability of bacteriorhodopsin (bR) solubilized by Triton X-100 (TX-100) was studied by measuring the denaturation kinetics in the dark and under illumination, and compared with the structural stability of bR solubilized by octyl-${\beta}$-glucoside (OG). In the dark, bR solubilized by TX- 100 was more stable than bR solubilized by OG. Under illumination, bR solubilized by TX-100 showed light-induced denaturation in the same manner as bR solubilized by OG. These results in the dark well correlated with the experimental results of the visible CD band. Although solubilized bR in the TX-100 concentration range of 2-50 mM showed almost identical positive CD band and did not denature in the dark at 35$^{\circ}$C, the kinetic constant of the photobleaching increased with the increase of TX-100 concentration. These results suggested that photo-intermediates of solubilized bR are destabilized by TX-100 micelles.

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Expression in Successive Generations of bar Gene Introduced in Petunia (Petunia에 도입된 bar Gene의 세대진전에 따른 발현 양상)

  • Ha, Young-Min;Park, Sang-Mi;Kim, Zhoo-Hyeon
    • Journal of Plant Biotechnology
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    • v.31 no.4
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    • pp.261-266
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    • 2004
  • This experiment was carried out to confirm the stability of bar gene introduced into petunia plant through Agrobacterium-mediated transformation, in successive generation, or after crossing or back-crossing. Some of different 25 transgenic plants were used in crossing and back-crossing to wild type, or repeated-selfing to T$_4$ generation. On the processing of experiment, it was found that some lines lost their resistant ability to herbicide basta, or showed non-Mendelian segregation mode: produced much more susceptible segregants than resistant plants. Even though there are exceptional cases, which was off from expected, the genetic stability of bar gene introduced could be confirmed strongly, because in almost case, the segregation of resistant and susceptible plants to basta was done under Mendelian-law according to single gene dominant model.

Development of Protein Delivery System using Pullulan Acetate Microspheres (PAM) (플루란 아세테이트 미립구를 이용한 단백질 전달 시스템 개발)

  • Na, Kun;Choi, Hoo-Kyun
    • Journal of Pharmaceutical Investigation
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    • v.36 no.2
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    • pp.115-121
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    • 2006
  • The aim of this study was to develop new protein/peptide depot system instead of poly(DL-lactic acid-coglycolic acid) (PLGA) microspheres. Pullulan was chemically modified by the addition of acetic anhydride (pullulan acetate; PA) and then investigated as new depot system for protein/peptide delivery. PA microspheres (PAM) with lysozyme as a model protein were prepared by w/o/w double emulsion method. The microspheres had a mean size of 10-50 mm with a spherical shape. The size distributions reduced with increasing the degree of acetylation. The loading efficiency of lysozyme was also increased. Lysozyme aggregation behavior in the microsphere was monitored to estimate the change of protein stability during preparation step. The ratios of protein aggregation in PAMs are lower than that of PLGA microsphere, in particular, PA 5 showed lowest as about 16%. The result indicated that the increase of acetylation suppressed the aggregation of protein. The release profiles of lysozyme from PAMs were significantly different. High acetylation effectively improved lysozyme release kinetics by reducing initial burst release and extending continuous release over a period of time. To check the effect of preservation for structural stability of lysozyme, the activity of lysozyme released from PA 5 was also observed. The activity of lysozyme was maintained almost 100% for 25 day. Therefore, PAM may become to a useful carrier for delivery of protein/peptide drugs, if it will be supported by biocompatibility and biodegradability results.

Experimental Study on the Stability Enhancement of Nonpremixed Flames in Coflow Jets (동축류 제트에서 전기장에 의한 화염 안정성 증진에 대한 실험적 연구)

  • Won, Sang-Hee;Ryu, Seung-Kwan;Chung, Suk-Ho;Cha, Min-Suk
    • 한국연소학회:학술대회논문집
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    • 2007.05a
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    • pp.191-196
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    • 2007
  • The enhancement of flame stability in coflow jets has been investigated experimentally by observing the liftoff behaviors of nonpremixed propane and methane flames in the electric fields. The liftoff or blowoff velocities has been measured in terms of the applied AC voltages and frequency. The experimental results showed that the liftoff velocity could be extended significantly just by applying the high voltage to the central fuel nozzle both for propane and methane. As increasing the applied voltage, the liftoff velocity increases almost linearly with the applied voltage and have its maximum value at certain applied voltage. After that, the liftoff velocity showed decrease with the applied voltage. Through the experimental observation, we found that the liftoff velocity could be correlated well with the applied voltage and frequency in the linearly increasing regime. And after having maximum in the liftoff velocity, it was observed that the liftoff velocity decreases with the applied voltage irrespective of AC frequencies. To visualize the change of flame structure with electric fields, planar laser induced fluorescence technique was adopted, and the enhancement of flame stability has been explained based on the flame structural change in electric fields.

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A Development of Digital Control System for FWPT In Nuclear Power Plant (원전 급수펌프 구동용 터빈 제어시스템 개발)

  • Choi, In-Kyu;Jeong, Chang-Ki;Kim, Byoung-Chul;Kim, Jong-An;Woo, Joo-Hee
    • Proceedings of the KIEE Conference
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    • 2006.07d
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    • pp.1885-1886
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    • 2006
  • The thermal energy from nuclear fission is transferred to the steam generator which is a kind of a large heat exchanger. After the feedwater is injected into the steam generator and absorbs the thermal energy, it is converted into the steam. This steam goes into the turbine. The balance between the generated energy and the consumed energy is required for the nuclear power plant to be stable. For the purpose of which, the feed water, a parameter for energy transfer, should be controlled in stability. Usually, the nuclear power plants are operated in base load in the view of power system for the stability of fission system. Therefore, though there will be almost no unbalance, there can be some instability from unbalance in case of startup/shutdown or disturbance. In this case, the controllability of feedwater pump is very important for the quick recover of stability.

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Effects of Ca Implantation on the Sintering and Crack Healing Behavior of High Purity $Al_2$O$_3$ Using Micro-Lithographic Technique-III: Stability of Crack-Like Pore (Ion Implantation으로 Ca를 첨가된 단결정 $Al_2$O$_3$의 Crack-Like Pore의 Healing 거동-III: Stability of Crack-Like Pore)

  • 김배연
    • Journal of the Korean Ceramic Society
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    • v.36 no.9
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    • pp.887-892
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    • 1999
  • The inner crack-like pore with controlled amount of Ca impurity in the high purity alumina single crystal sapphire had been created by micro-fabrication technique which includes ion implanation photo-lithography Ar ion milling and hot press technique. The crack-like pores in two-hour hot pressed specimen were extremely stable even after heat treating at 1,80$0^{\circ}C$ for 5 hours almost no healing was observed. But the crack-like pores in one-hour hot pressed specimen at 1,30$0^{\circ}C$ were healed by heat treatment and the amount of healing was increased with the heat treatment time and temperature and the amount of Ca addition. The edges of crack-like pore parallel to <1100> direction in (001) basal plane were stable but the edges normal to this direction in (00101) plane <1120> direction were unstable to facetting This means that the surface energy of alumina along the <1100> direction in (0001) basal plane in much lower than <1120> direction.

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A Study on the Stability Evaluation of Soil Slope according to inclination of upper Natural Slope (상부자연사면 경사에 따른 토사사면의 안정성 평가에 관한 연구)

  • Lee, Jeong-Yeob;Kim, Jin-Hwan;Lee, Jong-Hyun;Gu, Ho-Bon
    • Proceedings of the Korean Geotechical Society Conference
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    • 2004.03b
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    • pp.580-585
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    • 2004
  • The purpose of this study is the stability evaluation of soil slope according to inclination of upper natural slope. Upper natural slope breeds loss of slope by inflow in slope of surface water by rainfal1 and f1uctuation of amount of materials in slope through method of cutting slope according to degree of inclination. Basis of standard inclination does not consider of inclination of upper natural slope and is presented uniformly. Therefore, in this study, analyzed stability of inclination of upper natural slope through limit equilibrium analysis. Result is same as following. First, safety factor through limit equilibrium analysis is almost direct decrease when gradient of soil slope is 1:1.2, 1:1.5. However, when gradient of soil slope is 1:1.0, 1:0.7, if sinclination of upper natural slope are $20^{\circ}$, it shows tendency that decrease of safety factor becomes low rapidly. Second, when when gradient of soil slope is fixed, inclination of upper natural slope increase tendency(maximum 3.0 times) that decrease of safety factor.

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