• 대한한의학회지
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• 제36권2호
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• pp.43-49
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• 2015

Objectives: We evaluated the effect of the traditional Korean medical therapy of catgut-embedding therapy in patients with carpal tunnel syndrome (CTS). Methods: Thirteen patients(20 hands) with CTS underwent catgut-embedding therapy once per week for a total of 1-4 sessions. We measured the time to tingling in the fingers on performing Phalen's test. We also had patients use a visual analog scale (VAS) to indicate the severity of tingling. We also asked about the awakening time at night due to pain and tingling. We controlled the treatment as being limited to four sessions. Even if a patient had not been treated for four sessions, we ended the patient's treatment if symptoms resolved. Results: Patients who received catgut-embedding therapy showed significant improvements in the clinical symptoms of CTS. After treatment, in a total of 19 hands, the status of fourteen was changed from positive to negative in Phalen's test and the average of tingling occurrence time in that test was delayed. Among the 20 hands, the VAS in eight hands changed to zero and the average of VAS score decreased. Furthermore, in nine patients, four could sleep well without the use of a splint. Conclusions: Patients undergoing this traditional Korean medical therapy showed alleviation of finger tingling after even a single treatment. We thus concluded that this traditional Korean catgut-embedding therapy, may be effective for treating CTS. However, to confirm the effects of catgut-embedding therapy on CTS, further tests are required, including under the defined, strict conditions of a randomized controlled trial.

• 대한한의학회지
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• 제31권2호
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• pp.36-47
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• 2010

Objective: The purpose of this study was to investigate the effects of skin application with Gelidium amansii extract on skin with deep second degree burns in mice. Methods: BALB/c mice were divided into four groups: normal (NOR) group; burn-elicited mice (CON) group, Silmazine-treated mice after burn elicitation (ST) group, and Gelidium amansii-extract treated mice after burn elicitation (GT) group. To examine the skin recovery effect after burn, changes of burn area, angiogenesis and histologic structure were analyzed. To measure effect of edema regulation, matrix metalloproteinase-9 (MMP-9) was analyzed. To estimate the skin regenerative & stable effect, 5-bromo-2'-deoxyuridine (BrdU) and substance P were analyzed. Results: 2 weeks later, 1. The size of burn area decreased in the GT and ST groups more than the CON group. 2. Alleviation of angiogenesis appeared in the GT and ST groups more than in the CON group. 3. Blood clot, epithelial cell hyperplasia, and inflammatory cell infiltration declined in the GT and ST groups more than in the CON group. 4. MMP-9, BrdU, and substance P positive reaction decreased in the GT and ST groups more than in the CON group 5. In the comparative study, the GT group was superior to the ST group. Conclusion: The skin application of Gelidium amansii extract could lessen skin damage by the medium of regulation MMP-9 activation. This skin stabilization was induced in mice with deep second degree burns.

• 보건행정학회지
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• 제20권4호
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• pp.1-18
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• 2010

Much policy attention has been directed to the concentration of patients in large hospitals, especially in tertiary care hospitals. In order to address the problem, the government has enforced referral requirement for accessing care in tertiary care hospitals by denying insurance benefits to the patients who do not observe the requirement. This approach somehow has failed to produce expected effects although it still exists in theory. The concentration of patients in a certain type of providers results in the distortion of functional differentiation among various types of providers and vice versa. Thus the approaches for the alleviation of the problem should be directed to both patients and providers. However, policy approaches has so far focused on ways of directly affecting patients' choice of a provider neglecting the effects of providers. Based upon the observation, this paper has reviewed selected issues that should be considered in agenda setting for policies concerned with the concentration of patients in large hospitals or the distortion of functional differentiation among health care providers. A brief discussion of each of the issues suggests three general guidelines for the formulation and implementation of policies intended to address the problem. First, attention should be directed to both patients and providers. Secondly, it is necessary to employ diverse measures including regulation, incentives and administrative supports. Thirdly, some of the approaches should be planned from a long range perspective, for it often takes a long time to change some aspects of health care utilization and provision.

• Advances in aircraft and spacecraft science
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• 제4권2호
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• pp.145-167
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• 2017

The presented paper gives an overview of several projects addressing the experimental characterization and control of the buffet phenomenon on 3D turbulent wings in transonic flow conditions. This aerodynamic instability induces strong wall pressure fluctuations and therefore limits flight domain. Consequently, to enlarge the latter but also to provide more flexibility during the design phase, it is interesting to try to delay the buffet onset. This paper summarizes the main investigations leading to the achievement of open and closed-loop buffet control and its experimental demonstration. Several wind tunnel tests campaigns, performed on a 3D half wing/fuselage body, enabled to characterize the buffet aerodynamic instability and to study the efficiency of innovative fluidic control devices designed and manufactured by ONERA. The analysis of the open-loop databases demonstrated the effects on the usual buffet characteristics, especially on the shock location and the separation areas on the wing suction side. Using these results, a closed-loop control methodology based on a quasi-steady approach was defined and several architectures were tested for various parameters such as the input signal, the objective function, the tuning of the feedback gain. All closed-loop methods were implemented on a dSPACE device able to estimate in real time the fluidic actuators command calculated mainly from the unsteady pressure sensors data. The efficiency of delaying the buffet onset or limiting its effects was demonstrated using the quasi-steady closed-loop approach and tested in both research and industrial wind tunnel environments.

• 한국토양비료학회지
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• 제48권4호
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• pp.312-317
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• 2015

This study was conducted to evaluate effects of diethylene triamine penta acetic acid (DTPA) treatment on growth of red pepper and nutrient availability to salt accumulated soil in the plastic film house. The treatments were no application (Control), chemical fertilizers (NPK), DTPA (0.06, 0.13, and 0.19 mM) and the half of chemical fertilizers (NPK) with DTPA 0.06 mM. Fruit yield of red pepper showed no significant difference between the treatments (control, NPK, DTPA 0.06 mM, 0.13 mM, except for DTPA 0.19 mM. Red peppers were killed by DTPA 0.19 mM treatment because the high concentration of DTPA was toxic to crop. However, dry mass (stem and leave) and nutrient uptake of red pepper in DTPA 0.06 mM treatment increased significantly compared with those of control. In particular, nutrient uptake of red pepper in DTPA 0.06 mM treatment increased in the order of Fe, Mn, and Zn > Ca and Mg > K, as the magnitude of the stability constants of DTPA. Thus the application of DTPA 0.06 mM was the most effective for the alleviation of nutrient accumulation in the plastic film house soils.

• Journal of Acupuncture Research
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• 제36권2호
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• pp.100-106
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• 2019

Background: In Korean medicine, carpal tunnel syndrome is treated by stimulating the acupoints around the wrist. Although a deep understanding of anatomy and guidance is needed to stimulate these acupoints to avoid undesirable side-effects, currently there are no published guidelines for acupotomy treatment. The aim of this study is to evaluate the effectiveness and safety of fluoroscopy-guided acupotomy compared with conventional acupotomy treatment. Methods: This is a randomized, patient-assessor, patient blind, parallel clinical trial. A total of 30 patients will be enrolled at Wonkwang University Gwangju Hospital, and will be allocated to either an experimental group or a control group. The experimental group will be treated using fluoroscopy-guided acupotomy and the control group will be treated using the conventional acupotomy method. Results: The primary outcome measure will be identification of a cross-section area of the median nerve measured by ultrasonography, and the secondary outcome measure will be the alleviation of pain measured by the Visual Analogue Scale, improvement in the Nerve Conduction Study, Tinel test, Phalen's test, EuroQol 5-dimension scale, and Boston Carpal Tunnel Questionnaire score. Safety components will be measured by monitoring vital signs, electrocardiographs, blood tests, general chemical tests, urine tests and pregnancy tests. In addition, observations for adverse effects will be performed during the trial. Conclusion: This study will provide a more effective, and less harmful way of treating carpal tunnel syndrome compared with conventional acupotomy. Fluoroscopy-guided acupotomy will help practitioners to be accurate in direction and depth of the needle for treating carpal tunnel syndrome.

• Journal of Preventive Medicine and Public Health
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• 제57권2호
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• pp.108-119
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• 2024

Objectives: Abrupt changes in air pollution levels associated with the coronavirus disease 2019 (COVID-19) outbreak present a unique opportunity to evaluate the effects of air pollution on influenza risk, at a time when emission sources were less active and personal hygiene practices were more rigorous. Methods: This time-series study examined the relationship between influenza cases (n=22 874) and air pollutant concentrations from 2018 to 2021, comparing the timeframes before and during the COVID-19 pandemic in and around Thailand's Khon Kaen province. Poisson generalized additive modeling was employed to estimate the relative risk of hospitalization for influenza associated with air pollutant levels. Results: Before the COVID-19 outbreak, both the average daily number of influenza hospitalizations and particulate matter with an aerodynamic diameter of 2.5 ㎛ or less (PM_2.5) concentration exceeded those later observed during the pandemic (p<0.001). In single-pollutant models, a 10 ㎍/m³ increase in PM_2.5 before COVID-19 was significantly associated with increased influenza risk upon exposure to cumulative-day lags, specifically lags 0-5 and 0-6 (p<0.01). After adjustment for co-pollutants, PM_2.5 demonstrated the strongest effects at lags 0 and 4, with elevated risk found across all cumulative-day lags (0-1, 0-2, 0-3, 0-4, 0-5, and 0-6) and significantly greater risk in the winter and summer at lag 0-5 (p<0.01). However, the PM_2.5 level was not significantly associated with influenza risk during the COVID-19 outbreak. Conclusions: Lockdown measures implemented during the COVID-19 pandemic could mitigate the risk of PM_2.5-induced influenza. Effective regulatory actions in the context of COVID-19 may decrease PM_2.5 emissions and improve hygiene practices, thereby reducing influenza hospitalizations.

• 대한영상의학회지
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• 제84권5호
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• pp.1017-1030
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• 2023

증상이 있는 양성 갑상선결절의 비수술적 치료법인 고주파 절제술은 결절 조직을 열로 소작하여 부피를 감소시키고, 이로 인해 증상의 완화와 외견상 문제를 해결한다. 고주파절제술의 적응증은 2회 이상 세포/조직검사로 양성이 확인된 결절에서 의학적 치료가 필요한 주관적 또는 외견상의 임상증상이 있는 경우이다. 고주파 절제술은 1년의 단기 추적에서 매우 양호한 성적을 보이지만 3년 이상의 장기 추적에서는 20%-30% 결절의 재성장이 발생한다. 따라서 장기 추적을 전제로 하는 고주파절제술 후 환자 관리에서는 재성장을 관리하는 것이 핵심이다. 재성장은 치료 전 결절부피가 큰 경우, 혈관성이 높거나 증가하는 경우 잘 발생하며, 최근에는 수분 박리(hydrodissection), 동맥우선소작법, 정맥소작법등 새로운 기술들이 도입되어 재성장을 억제하고 있다. 또한 적절한 기준을 적용하여 재치료를 하는 것이 재성장을 관리하고 치료 효과를 오래 지속시키는데 중요하다. 고주파 절제술은 근본적으로 수술의 대안이므로 일시적 효과를 거두는 것이 아니라 영구적으로 수술을 회피하도록 하는 것이 궁극적인 목표이다.

• 대한원격탐사학회지
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• 제36권2_1호
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• pp.179-197
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• 2020

지형 정규화 기법은 영상 촬영 시의 광원, 센서 및 지표면 특성에 따라 발생하는 밝기값 상의 지형적인 영향을 제거하는 방법으로, 지형 조건으로 인해 동일 피복의 픽셀들이 서로 다른 밝기값을 지닐 때 그 차이를 감소시킴으로써 평면 상의 밝기값과 같아 보이도록 보정한다. 이러한 지형적인 영향은 일반적으로 산악 지형에서 크게 나타나며, 이에 따라 산불 피해 지역 추정과 같은 산악 지형에 대한 영상 활용에서는 지형 정규화 기법이 필수적으로 고려되어야 한다. 그러나 대부분의 선행연구에서는 중저해상도의 위성영상에 대한 지형 보정 성능 및 분류 정확도 영향 분석을 수행함으로써, 고해상도 다시기 영상을 이용한 지형 정규화 기법 분석은 충분히 다루어지지 않았다. 이에 본 연구에서는 PlanetScope 영상을 이용하여 신속하고 정확한 국내 산불 피해 지역 탐지를 위한 각 밴드별 최적의 지형 정규화 기법 평가 및 선별을 수행하였다. PlanetScope 영상은 3 m 공간 해상도의 전세계 일일 위성영상을 제공한다는 점에서 신속한 영상 수급 및 영상 처리가 요구되는 재난 피해 평가 분야에 높은 활용 가능성을 지닌다. 지형 정규화 기법 비교를 위해 보편적으로 이용되고 있는 7가지 기법을 구현하였으며, 토지 피복 구성이 상이한 산불 전후 영상에 모두 적용, 분석함으로써 종합적인 피해 평가에 활용될 수 있는 밴드 별 최적 기법 조합을 제안하였다. 제안된 방법을 통해 계산된 식생 지수를 이용하여 화재 피해 지역 변화 탐지를 수행하였으며, 객체 기반 및 픽셀 기반 방법 모두에서 향상된 탐지 정확도를 나타내었다. 또한, 화재 피해 심각도(burn severity) 매핑을 통해 지형 정규화 기법이 연속적인 밝기값 분포에 미치는 효과를 확인하였다.

• 기본간호학회지
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• 제2권1호
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• pp.37-43
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• 1995

This study was conducted to compare the severity of cannulation pain in hemodialysis patients after topical application of EMLA cream and local injection of lidocaine and evaluated side effects and problems accompanied by the former. Twenty patients, who were on hemodialysis from September 1 to October 15, 1994 at the Kangnam St. Mary's Hospital, Catholic University Medical College, were divided into two groups of ten. To conduct a cross over study, two groups were placed on four repeated methods with lidocaine followed by four repeated methods with EMLA cream and vice versa, respectively, while the severity of cannulation pain was being measured according to a Visual Analogue Scale with each methods. The results are follows : 1) The scale of pain was recorded as $4.56{\pm}1.38$ and $2.05{\pm}1.36$ points for methods with lidocaine and EMLA cream, respectively, indicating the less severe pain with EMLA cream. 2) Local side effects such as itching(4 cases, 5.0%)and pallor (5 cases, 6.3%)were observed with methods with EMLA cream but disappeared before the completion of hemodialysis. 3) Problems associated with local lidocaine were pain at the injection of anesthetic (27cases, 16.9%)and fear for needle insertion(6 cases, 3.8%). The most frequent problems with EMLA cream application were an inconvenience in use (11 cases, 6.9%)and tedious long pretreatment time(11 cases, 6.9%), those associated with inconvenience in cream applying procedures. 4) Twelve out of twenty patients(60.0%) responded with yes to a continued use of EMLA cream in spite of problems with cream application and economical difficulties in purchasing. These results indicate that 5% EMLA cream used as a local anesthetic in hemodialysis significantly reduces cannulation pain and lacks side effects, thus serving as a suitable method for the alleviation of cannulation pain and inconvenience in hemodialysis and the relief of psychological stress of nurses.