• Title/Summary/Keyword: alcohol dependence

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The Effects of Comorbid Anxiety Disorder and Substance use Disorder on Major Depressive Disorder (공존하는 불안장애와 물질사용장애가 주요우울증에 미치는 영향)

  • Shin, Jae Hyun;Kim, Jung Bum;Jung, Sung Won
    • Anxiety and mood
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    • v.9 no.2
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    • pp.93-100
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    • 2013
  • Major depressive disorder causes significant dysfunction and disability. Many of depressed patients tend to have cormobid anxiety disorders, substance use disorders and personality disorders, and so on. In this study, we reviewed researches about the effects of comorbid anxiety disorder, substance use disorder on depressive symptoms, progress, treatment, etc. In addition, the latest knowledges related to treatment was reviewed. If the symptoms of anxiety disorder coexist, They leads to the deterioration of the course and has an adverse effect on treatment response. Comorbid substance use disorder, such as alcohol dependence, causes worsening of symptoms and progression, and a loss of therapeutic response. Therapeutic clinical guidelines and instructions to comorbid psychiatric disorders on major depressive disorder was not established clearly, but consensus-based or evidence-based studies will be necessary for treatment for comorbid psychiatric disorders on major depressive disorder.

Influencing Factors on Smoking Cessation Motivation of Adult Males (성인남성의 금연동기 영향요인)

  • Yoon, Young Mi;Yang, Eun Kyung;Shin, Sung Rae
    • Korean Journal of Adult Nursing
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    • v.24 no.5
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    • pp.520-530
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    • 2012
  • Purpose: This research analyzed the different factors that influenced smoking cessation motivation. Methods: Subjects were both current and past male adult smokers. Data collection was conducted in four small businesses in Seoul and one public enterprise in Gyeonggi-Province from December 10, 2011 to January 30, 2012. Reasons for Quitting (RFQ) scale which was developed by Curry et al. was used for data collection. There were 350 participants and 324 (93%) questionnaires were used for the statistical analysis. Results: Participant's level of motivation varied by present smoking, quit attempt, smoking cessation counseling, level of nicotine dependence, stages of smoking cessation, and types of smoking. Participant's drinking pattern, smoking cessation counseling, social seeking type (G) and stages of smoking cessation had a 13% explanatory power for being motivated to stop smoking. Conclusion: For participants who drink alcohol regularly, who do not participate in smoking cessation counseling and those who are in the pre-contemplation stage for smoking cessation are candidates for future smoking cessation intervention programs or smoking cessation motivation programs.

Psychological Characteristics of Adult Sexual Offenders in South Korea (한국 성인 성범죄자의 개인 수준 심리적 특성 연구)

  • Jung, Min-Chul;Cho, Young-Il
    • The Journal of the Korea Contents Association
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    • v.15 no.3
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    • pp.88-100
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    • 2015
  • This research study was aimed to identify the psychological characteristics of sex offenders. In order to achieve those objectives, 123 sexual offenders, 102 common criminals, and 162 normal people were surveyed. We reviewed the previous studies examined the psychological characteristics of sexual offenders and summarized main variables related sexual offender at the individual level. Those variables included depression, anger, self-esteem, empathy, impulsivity, shame, psychopath, alcohol dependence. Results showed that the levels of depression, self-esteem, impulsivity, impulsion-cognitive, psychopathy were significantly different among the groups. The limitations and implications of this study and suggestions for future research are discussed.

Janis Joplin's transgression in blues tradition: focusing on blues performance (블루스 전통에서 바라본 제니스 조플린의 위반 : 공연을 중심으로)

  • Choi, Hayoung
    • English & American cultural studies
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    • v.14 no.1
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    • pp.287-310
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    • 2014
  • While Janis Joplin is generally known as a hippie rock star of an untimely death to Korean audience, she is more strongly evoked in the image of blues mama in American context. Blues, definitely based on African-American vernacular tradition, is defined as a matrix, which is "a point of ceaseless input and output, a web of intersecting, crisscrossing impulses always in productive transit," to borrow Houston A. Baker's expression. This article explores how her life and music can be understood in blues tradition, especially in terms of personal and social transgression for which she was criticized, focusing on her blues performance. First of all, born and growing up in southern Texas between 1940s and 1960s, she expressed her innate suspicion against segregation and white supremacy, actively embracing rich black musical heritage of the area. Second, against the normative social and moral expectation of a middle class white woman to be a suburban housewife, she sought her own desire, whether it was professional ambition or sexual possibility. Third, beyond the selling image of a heterosexually lascivious blues mama, she dared to be a homosexual and bisexual, while it was not publically acknowledged. Along with her alcohol and drug dependence, such transgressions against normative social expectation were not made without her inner conflict, leaving a trace of trauma, hesitation, and the blues. While she was "buried alive in the blues," as a sacrifice at the altar of the 1960s, she still remains "alive" provoking "fire inside of everyone of us."

Synergistic anticancer activity of disulfiram/copper against mouse lymphoma cells (마우스 림프종세포에 대한 disulfiram/copper의 항암증진효과)

  • Jung, Haebeen;Joo, Hong-Gu
    • Korean Journal of Veterinary Research
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    • v.62 no.1
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    • pp.3.1-3.7
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    • 2022
  • Disulfiram (DSF) is a marketed drug to treat patients with alcohol dependence by inhibiting aldehyde dehydrogenase. Over the last few decades, DSF has been shown to have anticancer effects through different mechanisms. Moreover, this effect can be elevated when used with copper (Cu). Subsequent studies have been conducted on various cancers, but few on lymphoma. This study investigated the anticancer effects of DSF on lymphoma and how this effect changed when treated with Cu. DSF synergistically decreased the metabolic activity of EL4 lymphoma cells when combined with Cu. At 1 µM of DSF alone, the metabolic activity of EL4 cells decreased by 49% compared to the control, whereas it decreased by 87% with a DSF + CuCl2 treatment. Rhodamine 123 and 2',7'-dichlorofluorescein diacetate staining showed that DSF induced the reduction of the mitochondrial membrane potential and promoted the production of reactive oxygen species. In particular, the combined treatment of DSF + Cu induced cell death based on multiple assays, including annexin V-fluorescein isothiocyanate/propidium iodide staining. Overall, DSF has anticancer effects on lymphoma cells and exhibits synergistic effects when combined with Cu. This study provides some valuable information to broaden the use of DSF in clinics and basic research.

Relationships between Depressed Mood and Life Style Patterns in Koreans Aged 40 Years (만 40세 성인의 우울기분과 생활습관과의 관계)

  • Chu, Ji Eun;Lee, Heejin;Yoon, Chung Ha;Cho, Han-Ik;Hwang, Ji-Yun;Park, Yoon Jung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.5
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    • pp.772-783
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    • 2014
  • This study aimed to investigate the relationships between depressed mood and life style patterns, including smoking, alcohol drinking, and physical inactivity in Koreans aged 40 years, which is a critical life transition period. Based on the Life Transition Period Health Examination at the Korea Association of Health Promotion conducted in 2011 (n=27,684), participants were categorized into a depressed mood group and a non-depressed mood group based on the results of the Primary Mental Health Questionnaire. The depressed mood group showed higher tendency for smoking compared to the non-depressed mood group. Current and ex-smokers were about twice as likely to have a depressed mood as the non-smokers. The prevalence of nicotine dependency was significantly higher in the depressed mood group. The number of days and amount of alcohol consumption were significantly correlated with depressed mood. The prevalence of alcohol dependence and alcohol abuse was higher in the depressed mood group than in the non-depressed mood group. The frequency of high-intensity exercise per week was negatively correlated with the number of people with a depressed mood. This study showed the significant relationships between depressed mood and smoking, alcohol drinking, and physical activity in adults during an important life transition period. This implies that the development of proper lifestyle intervention or education may be needed to prevent depressed moods in this age group.

Factors Affecting Problematic Drinking by University Students in Chuncheon Area (춘천지역 대학생의 문제음주에 영향을 미치는 요인)

  • Kim, Yoon-Sun;Kim, Bok-Ran
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.6
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    • pp.934-942
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    • 2014
  • The purpose of this study was to investigate factors affecting problematic drinking by university students in the Chuncheon area. Lifelong drinking rate of subjects was 98.1%. Problematic drinking rates according to AUDIT (alcohol use disorders identification test) were as follows: 21.3% 'no problem', 58.0% 'at-risk drinking', 10.0% 'alcohol abuse' and 10.7% 'alcohol dependence'. Research has shown that problematic drinking is more prevalent among freshmen, early drinkers, those with hypochondria, and students who are less satisfied with their campus life or whose own parents are frequent drinkers. It has been shown that more serious problematic drinking is associated with higher 'positive alcohol outcome expectancies' and 'coping motives for drinking', and 'recognition level of drinking cultures' is considered less desirable. Multiple regression analysis revealed that 'coping motives for drinking' was the most significant variable affecting the problematic drinking of university students. Developing and fostering various alcohol-reducing programs that largely focus on 'coping motives for drinking' will greatly contribute to solving problematic drinking.

Microwave hybrid sintering of NTC themistor (마이크로파 하이브리드 소결법에 의한 NTC 서미스터의 제조)

  • 최영락;안진용;안주삼;백동규;최승철
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.8 no.3
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    • pp.508-512
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    • 1998
  • The NTC thermistors were sintered by using microwave hybrid heating method at $1100^{\circ}C$~$1300^{\circ}C$ and those electrical properties were investigated. The obtained $B_{25^{\circ}C/85^{\circ}C}$ values from temperature dependence of electrical resisitivity were around 3100~3200 K which were almost the same values as conventionally sintered ones. Compared with conventional sintering process, this process could complete whole sintering process within 20 minutes. This the processing time and energy consumption could be reduced through this rapid heating by using microwave hybrid heating.t there were showed only two peaks, glycolide melting peak and lower molecular weight melting peak without lauryl alcohol. Conversion increased slowly with the reaction time up to 50 minutes, and then gave a sudden increase above that. The reaction time to disappear in glycolide melting peak during polymerization was shortened with the increase of lauryl alcohol content. Zero-shear viscosity of polyglycolic acid decreased with the increase of free acid content in glycolide.ssional energy and bending hysteresis increased. \circled3 Surface characteristics such as friction coefficient and thickness variation of highly shrinkage fabrics became relatively roughened state. \circled4 Since stiffened and roughened characteristics of highly shrinkage fabrics, drapabilities of them were significantly lowered. Additionally thermal insulation property of high shrinkage fabric was higher than that of low shrinkage fabric due to bulky and thickened feature. From the results, it is considered that the silk fabrics with high filling shrinkage have the good bulkiness and heat keeping properties and thus they have the suitable characteristics for high quality men's and women's formal garments.

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Thin-film optical waveguide $K^{+}$-ion sensor using the evanescent field absorption (소산장 흡수를 이용한 박막 광도파로형 칼륨이온센서)

  • Lee, Su-Mi;Koh, Kwang-Nak;Kang, Shin-Won
    • Journal of Sensor Science and Technology
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    • v.6 no.3
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    • pp.214-220
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    • 1997
  • A thin film optical waveguide sensor has been developed to measure and analyze quantitatively some inherent optical properties of biochemical substances. In this paper, two different kinds of thickness of thin film waveguide were prepared by RF sputtering of Corning-7059 glass(n = 1.588 at ${\lambda}=\;514nm$, Ar laser) on Pyrex glass substrates. We made a sensing membrane coated on the thin film waveguide with the poly(vinyl chloride-co-vinyl acetate-co-vinyl alcohol) (91 : 3 : 6) copolymer membrane based on $H^{+}$-selective chromoionophore and $K^{+}$-selective neutral ionophore and then proposed the thin film opptical waveguide ion sensor which can select a potassium ion. This sensor based ell the absorbance change by utilizing chromoionophore and neutral ionophore, which changes their absorption spectrum in the UV-vis region upon complexation of the corresponding ionic species, have been reported. The sensitivity dependence of the proposed sensor on interaction length, waveguide thickness, and content of a chromoionophore was investigated. This sensor has the measurement range of $10^{-6}M{\sim}1M$ for $K^{+}$ concentration and 90% response time of duration within 1 min. Also, our thin film optical waveguide sensor using the evanescent field was investigated as compared with conventional transmission sensor or optode sensor by the optical fiber. The sensitivity of thin-film waveguide $K^{+}$ sensor is higher than that of the conventional transmission sensor. The proposed sensor is expected to be useful to biochemical, medical, environmental inspection and so on.

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A Comparative Study on the Attitude toward Caring for Alcoholics of Nursing Students according to the Degree of Parents' Drinking Problem (부모의 음주문제정도에 따른 간호대학생의 알코올중독자 돌봄에 대한 태도 차이)

  • Kim, Ji-Seon;Kweon, Young-Ran
    • The Journal of the Korea Contents Association
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    • v.17 no.11
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    • pp.632-640
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    • 2017
  • Purpose: This study was to investigate the difference of attitude toward caring for alcoholics of nursing college students according to degree of parents' drinking problem. Methods: The subjects of this study were 281 students in the second and fourth grade students in nursing departments of 4 Universities located in G city. Data were analyzed by the mean and standard deviation, t-test. and ANOVA using SPSS 22.0 program.. Results: Parents' problem drinking perceived by the subjects was $3.70({\pm}5.85)$, $1.25({\pm}1.71)$ in the social drinking group(n=225), $8.59({\pm}2.07)$ in the alcohol abuse group(n=29), and alcohol dependence group (n=27) was $18.85({\pm}5.17)$ points. The average attitude toward caring for alcoholics was $45.25({\pm}6.49)$. The attitude toward caring for alcoholics showed a statistically significant difference depending on whether or not-they participated in the nursing practice of alcoholics. The attitude toward caring for alcoholics in nursing college students was negative as the parents' problem drinking was severe. Conclusion: The results of this study can be used as basic data for the development of psychiatric nursing education and counseling program for nursing college students whose parental drinking problems are serious in the future.