• Communications for Statistical Applications and Methods
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• v.6 no.1
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• pp.143-150
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• 1999

Ko(1998) proposed a procedure to enhance the efficiency of double sampling plans by allowing second-stage sample size and critical region to depend on first-stage evidence using constraint optimization approaches. In this study further developments of such plans by incorporating several practically possible researcher's aims into the optimization are considered. Comparisons are made with the optimal ordinary double sampling plan and also among them It is observed that it is to some extent possible to match the details of the optimization to certain qualitative methodological aims.

• Information and Communications Magazine
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• v.26 no.2
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• pp.44-52
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• 2009

본 고에서는 네트워크 기반 이종 액세스 망간 이동성 제어 기술인 AIMS(Access Independent Mobility Service) 기술을 소개한다. AIMS 기술은 제어계층과 데이터전달계층 분리를 통해 신속하고 안정적으로 제어 메시지를 전달하고, L2/L3 연동을 통한 고속 핸드오버를 지원하고, 최단 경로를 통한 데이터 전송을 지원하고, 사용자 선호 및 정책 기반의 접속 액세스 선택을 지원하며 이동성 제어를 위한 단말의 추가 기능을 최소화하는 특징을 갖는 네트워크 기반 이동성 제어 기술이다. AIMS 시스템을 이용하여 수행한 다양한 실험을 통해 얻은 망 적용시의 고려사항을 소개하고 이에 대한 방안을 AIMS시스템의 개선된 기능으로서 제시한다.

• The Journal of Korean Physical Therapy
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• v.19 no.5
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• pp.29-41
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• 2007

Purpose: The aim of this study was to examine the validity and reliability on Psychometric Arthritis Impact Measurement Scale-Short Form (AIMS-SF) in patients with knee osteoarthritis(OA). Methods: The sample consisted of 62 patients who had received physical therapy at the physical therapy units of the Andong Medical Center, Sungso Hospital, Ahn Orthopedic Surgery Clinic, and St. Luke Clinic in Andong city in June 2006. Questionnaire on the AIMS-SF was recruited by 5 physical therapists. The internal structure and reliability of the scales were evaluated by means of item-internal consistency(Cronbach's alpha coefficient: ${\alpha}$), item-discriminant validity, Pearson's relation coefficient. To explore construct validity we conducted a principal component factor analysis with varimax rotation analysis. The criterion for factor extraction was an eigenvalue >1.0. Results: 62 OA patients's an average $age{\pm}standard$ deviation was $53.8{\pm}14.4$ years (range: $40{\sim}81$ yr). The internal consistency reliability of 11 items, as estimated by Cronbach's ${\alpha}$ coefficient, was high ranging $0.60{\sim}0.78$ (except for 0.40 for mobility level and -0.48 for mood). The internal consistency reliability of item-each scale was also high $0.82{\sim}0.93$ (except for 0.48 for mood). Of 11 items, the item-discriminant validity on 6 items was high (${\alpha}$ coefficient range: $0.11{\sim}0.25$), however, others (0.57 for tension level, 0.48 for arthritis pain, 0.41 for walking and bending, and 0.40 for work) were a little low. The construct validity by factor analysis was a little low. Conclusion: In conclusion, the results reported here confirm the validity and reliability of the AIMS-SF in patients with OA of the knee. The Collection of information on health status using this instrument was acceptable to patients. A further prospective multi-center study will be necessary to prove the construct validity.

• Journal of muscle and joint health
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• v.8 no.2
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• pp.302-322
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• 2001

This study was carried out in order to examine the health status of arthritis patients living in K city of southern part of Korea. The data were collected with AIMS2 instrument from 56 subjects who were asked to complete the questionnaire by the trained surveyor. The AIMS2 has been approved useful instrument for assessing the outcome of various treatments and programs in rheumatic diseases. The component variables of the AIMS2 are Mobility, Walking and Bending, Hand and finger function, Arm function, Self-care tasks, Household tasks, Social activity, Support from family and friends, Arthritis pain, Work, Mood, Level of tension, The total number of items of AIMS 2 are 78. The results are as follows: The average age of the subjects was 58 years old and no gender difference. The mean scores of the 12 sub-concepts of AIMS2 are 15.0 of mobility, 12.16 of walking and of bending, 9.32 of hand and finger function, 9.03 of arm function, 13.53 of self-care tasks, 10.19 of household tasks, 15.09 of social activity, 19.58 support from family and friends, 13.82 of arthritis pain, work, 14.85 of level of tension, 15.12 of mood. The Cronbach Cronbach $\alpha$. is 0.72-91 for RA patients and 0.74-96 for OA patients. This results showed that the health status of Arthritis patients at home in K-city was almost not so serious, but the level of tension and mood were quite higher than the average score. Considering the results of this particular subjects, an appropriate rehabilitation program should be developed and implemented.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.3B
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• pp.526-535
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• 2010

In this paper, we propose the fault-tolerant network-based mobility management scheme for supporting multimedia services of broadcasting & communications convergence in fixed mobile convergence (FMC) networks. The proposed scheme is based on AIMS (Access Independent Mobility Service) which is developed for the mobility support among heterogeneous access networks. To support stable location management and handover control for a MN, the proposed scheme supports stable management of binding information by sensing network attachment and detachment of a mobile node (MN). In addition, the proposed fault-tolerant (FT) AIMS supports a function of message retransmission for the support of handover control message and a function of heartbeat message transmission for the support of stable access network environments to a mobile node. We evaluate and analyze the performance of the proposed scheme through the implementation of AIMS system test-bed.

• Journal of the Korean Institute of Intelligent Systems
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• v.11 no.1
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• pp.65-69
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• 2001

본 논문에서는, 고 중량 측정 장치를 위한 적응 지능형 모니터링 시스템(Adaptive Intelligence Monitoring System ; AIMS)을 제안한다. 지능형 알고리즘으로 퍼지 알고리즘과 FNN을 적용하였으며 고 신뢰도를 가지는 적응 지능형 모니터링 네트웍 시스템의 효용성을 확인한다.

• Korean Journal of Biological Psychiatry
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• v.11 no.2
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• pp.117-126
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• 2004

Objects:It has been reported that the incidence of tardive dyskinesia(TD), the remarkable abnormal involuntary movement, was higher in the schizophrenics with high blood sugar levels and that TD had been improved by small amount of insulin-injection for 90 days. And also it was generally known that the blood lipids were higher in the schizophrenics with tardive dyskinesia. Thus, we tried to replicate the correlations of abnormal involuntary movements with blood sugar levels and blood lipids in chronic schizophrenics treated with antipsychotics. Methods:Thirty-eight male schizophrenic inpatients who were stable in clinical state with medications, were included. The patients who had been already diagnosed as diabetes mellitus(DM), organic brain disorder, substance- related disorder, physical illness were excluded and also we excluded female patients to remove the hormonal effect on TD. Eleven patients who ranked higher(above five) in the Abnormal Involuntary Movement Scale(AIMS) were assigned into 2 groups, a dibenese group and a placebo group. Diabinese or placebos were administrated for 3 weeks with antipsychotics and AIMS was rechecked. Results:There were no correlations between the total AIMS scores and blood sugar and lipids levels in all subjects. The means of total and subscale scores(objective, face, and extremity) of AIMS did not reveal statistical significances between diabinese and placebo groups. However(total, jaw, face, upper arm, and objective feeling), were statistically higher in the diabinese group than those in the placebo group. And correlations of total cholesterol(TC) with fast blood sugar(FBS), weight with body mass index(BMI) and waist, total glycerol (TG) with BMI were statistically significant. Conclusion:In this study, there were statistical significances in the changes in ratings of AIMS scores between the diabinese group and the placebo group. Application of oral hypoglycemic agent might be a way of improving abnormal involuntary movements in schizophrenics with abnormal involuntary movements or TD. Althogugh it was not certain that there were correlations of abnormal involuntary movement with blood sugar and lipids, correlations of TC/TG with AIMS, of FBS with AIMS cautiously suggest that the regular check of $HbA_1C$, waist, and weight are recommended for schizophrenics.

• Journal of Korean Academy of Nursing
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• v.36 no.6
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• pp.917-924
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• 2006

Purpose: This study was to examine the effects of electrical muscle stimulation therapy on chronic knee pain in the elderly. Method: The research design was a one-group pretest-posttest design. The subjects were 45 (TE: 17, SE: 15, SY: 13) elderly, 65 years old and above with chronic knee pain. Pain was measured by the S-F McGill Pain Questuionnaire (S-F MPQ) and Arthritis Impact Measurement Scale (AIMS). Electrical muscle stimulation therapy experimental treatment was applied for 12 weeks, 3 times/week, 15 min/time. Data was collected from March 2005 to February 2006. Data was analyzed using the SPSS PC+ 12 version. Results: After receiving electrical muscle stimulation therapy, chronic knee pain in TE (S-F MPQ: t=-62.143, p=.000, AIMS: t=-29.155, p=.000), SE (S-F MPQ: t=-76.345, p=.000, AIMS: t=-39.323, p=.000), and SY (S-F MPQ: t=-43.691, p=.000, AIMS: t=-30.306, p=.000) groups were significantly decreased. Conclusion: Electrical muscle stimulation therapy can be a better effective primary nursing intervention for chronic knee pain for community dwelling elderly people with TE, SE, and SY.

• Journal of Korean Neurosurgical Society
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• v.66 no.2
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• pp.121-132
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• 2023

Objective : The parafascicular nucleus (PF) plays important roles in controlling the basal ganglia. It is not well known whether the PF affects the development of abnormal involuntary movements (AIMs). This study was aimed to find a role of the PF in development of AIMs using optogenetic methods in an animal model. Methods : Fourteen rats were underwent stereotactic operation, in which they were injected with an adeno-associated virus with channelrhodopsin (AAV2-hSyn-ChR2-mCherry) to the lateral one third of the PF. Behavior test was performed with and without optical stimulation 14 days after the injection of the virus. AIM of rat was examined using AIM score. After the behavior test, rat's brain was carefully extracted and the section was examined using a fluorescence microscope to confirm transfection of the PF. Results : Of the 14 rats, seven rats displayed evident involuntary abnormal movements. AIM scores were increased significantly after the stimulation compared to those at baseline. In rats with AIMs, mCherry expression was prominent in the PF, while the rats without AIM lacked with the mCherry expression. Conclusion : AIMs could be reversibly induced by stimulating the PF through an optogenetic method.

• Asian Pacific Journal of Cancer Prevention
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• v.18 no.11
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• pp.2919-2923
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• 2017

Objective: Anthocyanins belong to a class of flavonoids, exhibiting antioxidant and anti-inflammatory actions have been reported to have anti-cancer effects. Here, we investigated whether anthocyanins can inhibit cancer cell proliferation, invasion, and angiogenesis in human lung cancer A549 cells, which are critically involved in cancer metastasis. Methods: We used anthocyanins from fruits of Vitis coignetiae Pulliat (AIMs) which has been used in Korean folk medicine for the treatment of inflammatory diseases and cancers. We have performed cell proliferation assays, cell invasion assay, gelatin zymography, wound healing assay and western blotting to examine whether anthocyanins can inhibit cancer cell proliferation, invasion, and angiogenesis in A549 cells. Result: AIMs did not inhibit cancer cell proliferation on A549 cells. Also, AIMs suppressed cancer migration, and invasion by supressing MMP-2 and MMP-9 expression. The Immuno-blotting results also revealed that AIMs suppressed the proteins involved in cancer proliferation (COX-2, C-myc, cyclin D1), migration and invasion (MMP-2, MMP-9), anti-apoptosis (XIAP, and c-IAP2), adhesion and angiogenesis (ICAM-1, VEGF). Conclusion: This study demonstrates that the anthocyanins isolated from fruits of Vitis coignetiae Pulliat inhibit cancer proliferation, cancer migration, and invasion that is involve in cancer-metastasis. This study provides evidence that AIMs might have anti-cancer effects on human lung cancer.