• Title/Summary/Keyword: aging stability

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Concept of Constitution, Evaluative Norms and Prospect of Constitutional Theories (체질개념과 체질이론의 평가기준 설정 및 연구 전망)

  • Chi, Gyoo-Yong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.4
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    • pp.759-765
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    • 2006
  • In order to provide the methodology of researching constitutional theories, the original meaning and the source of the term, ti(體) and zhi(質) written in and other text were reviewed, and then components of constitution(體質) and some evaluative norms and prospect on constitutional theories were proposed. Ti(體) means body or 5 tissues or patterns of them and zhi(質) means quality in , so the temporary meaning of constitution was generally same with present one. But the temperament originated from Greek and Elizabethan era is thought that it corresponds with constitution, but it means generally body type and character and mental pathologic features. The fundamental requirements of constitutional theories are needed stability, creativity, clinical efficiency and reproductiveness for differentiating with classical diagnostics over the range of disease and aging of the subject. And heredity, universality and extensiveness were recommended as additional requirements for making level up the theories through long-term follow-up, and to evaluate these requirements detail items were proposed. More of these, weight rendering should be made respectively afterwards.

Probabilistic behavior of semi-active isolated buildings under pulse-like earthquakes

  • Oncu-Davas, Seda;Alhan, Cenk
    • Smart Structures and Systems
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    • v.23 no.3
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    • pp.227-242
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    • 2019
  • Seismic isolation systems employ structural control that protect both buildings and vibration-sensitive contents from destructive effects of earthquakes. Structural control is divided into three main groups: passive, active, and semi-active. Among them, semi-active isolation systems, which can reduce floor displacements and accelerations concurrently, has gained importance in recent years since they don't require large power or pose stability problems like active ones. However, their seismic performance may vary depending on the variations that may be observed in the mechanical properties of semi-active devices and/or seismic isolators. Uncertainties relating to isolators can arise from variations in geometry, boundary conditions, material behavior, or temperature, or aging whereas those relating to semi-active control devices can be due to thermal changes, inefficiencies in calibrations, manufacturing errors, etc. For a more realistic evaluation of the seismic behavior of semi-active isolated buildings, such uncertainties must be taken into account. Here, the probabilistic behavior of semi-active isolated buildings under historical pulse-like near-fault earthquakes is evaluated in terms of their performance in preserving structural integrity and protecting vibration-sensitive contents considering aforementioned uncertainties via Monte-Carlo simulations of 3-story and 9-story semi-active isolated benchmark buildings. The results are presented in the form of fragility curves and probability of failure profiles.

Determinants of Improving the Financial Security of Retired Women in Malaysia

  • ZAINUDDIN, Halimatul Nadia;MOHAMAD, Nor Edi Azhar;RAJADURAI, R. Jegatheesan V.;SAPUAN, Noraina Mazuin;SANUSI, Nur Azura
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.6
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    • pp.11-21
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    • 2022
  • The perspectives on aging women's financial security during their retirement years are based on their behavior, planning, and decision-making processes during their working years. Elderly women are considered vulnerable and have a longer life expectancy, lower-income, and limited financial understanding compared to males; therefore, drastic steps need to be taken to improve their financial stability and quality of life. The current study sought to determine the most important contributors to retired women's financial health by measuring the value of four factors/variables: capability, opportunity, willingness, and biopsychosocial. This study used a mixed model approach, with qualitative analysis in the first phase involving a focus group discussion session, a pilot analysis, and quantitative analysis for phase two involving the distribution and collection of questionnaires completed by retired women. The surveys were distributed across Malaysia in five distinct zones and yielded 339 usable replies to support the theory. The outcomes of the Multiple Regression Analysis in Malaysia revealed that capability, opportunity, and biopsychosocial factors are significant predictors of retired women's financial security, whereas the willingness indicator lacked statistical significance.

Protection of Skin Fibroblasts from Infrared-A-Induced Photo-Damage Using Ginsenoside Rg3(S)-Incorporated Soybean Lecithin Liposomes

  • Won Ho Jung;Jihyeon Song;Gayeon You;Jun Hyuk Lee;Sin Won Lee;Joong-Hoon Ahn;Hyejung Mok
    • Journal of Microbiology and Biotechnology
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    • v.33 no.1
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    • pp.135-141
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    • 2023
  • Protection of skin cells from chronic infrared-A (IRA) irradiation is crucial for anti-photoaging of the skin. In this study, we investigated the protective activity of Rg3(S) and Rg3(S)-incorporated anionic soybean lecithin liposomes (Rg3/Lipo) with a size of approximately 150 nm against IRA-induced photodamage in human fibroblasts. The formulated Rg3/Lipo showed increased solubility in aqueous solution up to a concentration of 200 ㎍/ml, compared to free Rg3(S). In addition, Rg3/Lipo exhibited superior colloidal stability in aqueous solutions and biocompatibility for normal human dermal fibroblasts (NHDFs). After repeated IRA irradiation on NHDFs, elevated levels of cellular and mitochondrial reactive oxygen species (ROS) were greatly reduced by Rg3(S) and Rg3/Lipo. In addition, cells treated with Rg3/Lipo exhibited noticeably reduced apoptotic signals following IRA irradiation compared to untreated cells. Thus, considering aqueous solubility and cellular responses, Rg3/Lipo could serve as a promising infrared protector for healthy aging of skin cells.

Development of Chatbot Self-Inspection Scenario for Structural Safety of Existing Reinforced Concrete Buildings (챗봇 활용 철근콘크리트 건축물 구조안전 자가점검 시나리오 개발에 관한 연구)

  • Yang, Jaekwang;Kang, Taewook;Shin, Jiuk
    • Journal of the Earthquake Engineering Society of Korea
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    • v.27 no.6
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    • pp.331-337
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    • 2023
  • Due to the aging of a building, 38.8% (about 2.82 million buildings) of the total buildings are old for more than 30 years after completion and are located in a blind spot for an inspection, except for buildings subject to regular legal inspection (about 3%). Such existing buildings require users to self-inspect themselves and make efforts to take preemptive risks. The scope of this study was defined as the general public's visual self-inspection of buildings and was limited to structural members that affect the structural stability of old buildings. This study categorized possible damage to reinforced concrete to check the structural safety of buildings and proposed a checklist to prevent the damage. A damage assessment methodology was presented during the inspection, and a self-inspection scenario was tested through a chatbot connection. It is believed that it can increase the accessibility and convenience of non-experts and induce equalized results when performing inspections, according to the chatbot guide.

The Effect of the SOD2 and SOD3 in Candida albicans on the Antioxidant System and its Potential as a Natural Antioxidant

  • Yeonju HONG;Min-Kyu KWAK
    • The Korean Journal of Food & Health Convergence
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    • v.10 no.2
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    • pp.13-17
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    • 2024
  • Oxygen is necessary to sustain life, but reactive oxygen species (ROS) produced by oxygen metabolism can cause mutations and toxicity. ROS can damage cellular macromolecules, leading to oxidative stress, which can accelerate cell death and aging. ROS generated in food affect the taste, color, and aroma of food, and high levels of ROS in meat can cause spoilage. Superoxide dismutase (SOD) plays an important role in scavenging ROS in food and reducing their toxicity to organisms. SOD exerts its antioxidant effect by catalyzing the breakdown of O2-• to H2O2. As a natural antioxidant, SOD has the ability to regenerate and maintain its activity over a long period of time without depletion, unlike chemical antioxidants that may have side effects or stability issues. This antioxidant effect of SOD has great potential in a variety of industries, and in the food industry it can be utilized to improve product quality and provide safe and healthy products to consumers. By disrupting the SOD2 and SOD3 genes in Candida albicans, we studied the effects of SOD2 and SOD3 genes on the antioxidant system, suggesting its potential as a natural antioxidant.

Understanding the Correlation Between Dorsiflexion Range of Motion and Dynamic Balance in Elderly and Young Adults (노인과 젊은 성인의 발목발등굽힘 관절가동범위와 동적 균형 상관성 대한 이해)

  • Seo, Hae-yong;Han, Ji-hye;Kim, Min-ju;Kim, Ah-yeon;Song, Yi-seul;Kim, Su-jin
    • Physical Therapy Korea
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    • v.25 no.2
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    • pp.22-29
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    • 2018
  • Background: Deficits of both ankle dorsiflexion range of motion (DFROM) and dynamic balance are shown in persons with chronic ankle instability and the elderly, with the risk of falls. Objects: This study aims to investigate the relationship between DFROM and dynamic balance in elderly subjects and young adults. Methods: Fifty-nine subjects were divided into three groups: ankle stability young group (SY), ankle instability young group (IY) and ankle stability older group (SO). We recruited three old subjects with ankle instability, but excluded them during a pilot testing due to the safety issue. DFROM was measured by weight bearing lunge test (WBLT) and dynamic balance was measured via star excursion balance test (SEBT) in anteromedial, medial, and posteromedial directions. The group differences in WBLT and SEBT and each group's correlation between WBLT and SEBT were detected using the R statistical software package. Results: The dorsiflexion range of motion was significantly different between the SY, IY, and SO groups. The SO group showed the highest DFROM and IY group showed the lowest DFROM (SY: $45.88{\pm}.66^{\circ}$, IY: $39.53{\pm}1.63^{\circ}$, SO: $47.94{\pm}.50^{\circ}$; p<.001). However, the SO group showed the lowest dynamic balance score for all SEBT directions (SY: $87.24{\pm}2.05cm$, IY: $83.20{\pm}1.30cm$, SO: $77.23{\pm}2.07cm$; p<.05) and there was no relationship between the dorsiflexion range of motion and dynamic balance in any group. Conclusion: Our findings suggest that ankle DFROM is not a crucial factor for dynamic stability regardless of aging and ankle instability. Other factors such as muscle strength or movement coordination should be considered for training dynamic balance. Therefore, we need to establish the rehabilitation process by measuring and treating ROM, balance, and muscle strength when treating young adults with and without ankle instability as well as elderly people.

An Empirical Analysis of Factors Influencing Seniors' Satisfaction with the Use of Wealth Management Services in Financial Institutions (시니어의 금융기관 자산관리 서비스 이용 만족도에 영향을 미치는 요인에 대한 실증 분석)

  • Park, Hyun-jung;Kang, Shin-gi
    • Journal of Venture Innovation
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    • v.6 no.3
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    • pp.221-240
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    • 2023
  • In a recent study conducted in South Korea, a nation grappling with the implications of an increasingly super-aged society, researchers empirically analyzed the factors influencing seniors' satisfaction with financial institutions' wealth management (WM) services. We surveyed 250 seniors who utilized financial institutions' wealth management services. Independent variables such as product(diversity, profitability, stability), employee(expertise, problem-solving ability, customer orientation), physical evidence, process, inheritance service, and trust service were carefully examined. Employing hierarchical regression analysis, we tested hypotheses within an established research model. The findings revealed that variables like product stability and profitability, employee problem-solving ability, customer orientation, process, inheritance service, and trust service significantly positively affected satisfaction with WM services. In contrast, no substantial association was detected between satisfaction and factors like product diversity, employee expertise, or physical evidence. Among the influential factors, the order of impact was determined to be employee customer orientation, problem-solving ability, trust service, product stability, inheritance service, product profitability, and process. This research provided essential insights into the nuanced preferences and needs of seniors concerning wealth management services. The detailed examination of the subject might also shed light on similar challenges faced in the other aging societies. As the global population continues to age, the implications of this study could reach far beyond the borders of South Korea. By understanding these key determinants of satisfaction, financial institutions worldwide can tailor their wealth management services to better meet the unique demands of the senior population.

Synthesis and Characterization of Layered Copper Hydroxides in Highly Concentrated Solution (고농도 용액에서 Layered Copper Hydroxides의 합성 및 특성)

  • Nam, Dae-Hyean;Choi, Choong-Lyeal;Kim, Kwang-Seop;Seo, Young-Jin;Park, Man
    • Korean Journal of Soil Science and Fertilizer
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    • v.43 no.6
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    • pp.872-879
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    • 2010
  • Layered copper hydroxides [LCHs, $Cu_2(OH)_3{\cdot}NO_3$] has the agricultural potentials as a fungicide because of its high crystallinity, excellent anion exchange capacity, and its regular layered particle size. The study, for the first time, has synthesized LCHs in highly concentrated solution and evaluated its physicochemical properties including the crystallinity and suspension stability. Optimal synthetic condition of LCHs was determined by crystallinity and stability of suspension as follow; 1) concentrations of $Cu(NO_3)_2$ and NaOH solutions were 3.0 M respectively, 2) reaction temperature and solution pH were $25^{\circ}C$ and 6.0, respectively, and 3) aging time after reaction was 2hr. Crystallinity of LCHs enhanced with increase in pH up to 9.0. Whereas, stability of suspension was decrease by increase in crystal size. Especially, increase in reaction temperature decreased stability of suspension. XRD patterns and SEM images exhibited that LCHs had regular layered particle size with 0.2~0.8 ${\mu}m$ and high crystallinity in optimal synthetic condition. The particle size was increased with increase in reaction temperature and pH. These results showed that LCHs synthesized in highly concentrated solution exhibited high stability of suspension as well as high crystallinity suitable to their potential as a fungicide.

Effect of Maternal Age on Chromosome Aberrations and Telomere Quantity in Chick Embryos (닭의 모체 연령에 따른 생산 배아의 염색체 이상 빈도 및 텔로미어 함량 분석)

  • Lee, Soo-Hee;Subramani, Vinod K.;Sohn, Sea-Hwan
    • Korean Journal of Poultry Science
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    • v.36 no.4
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    • pp.293-300
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    • 2009
  • The rate of fetus with abnormal chromosomes increase with maternal age. Nondisjunction of aging oocyte chromosome is a major reason for the increased rate of abnormalities. Telomeres are the ends of eukaryotic chromosome, which are essential for chromosome stability and are related in cell senescence. This study was carried out to analyze the chromosome aberration rate and amount of telomeric DNA in chick embryo along with maternal age. Fertilized eggs and blood were sampled from White Leghorn layers starting at 20 weeks through to 70 weeks age at 10 weeks interval. Chromosome aberration rate was analyzed by karyotyping. The amounts of telomeric DNA in embryonic cells and lymphocytes were quantified by Quantitative Fluorescence in situ Hybridization method. The chromosome aberration rate in chick embryos significantly differed with maternal age. The chromosome aberration rate increased at early laying period and beyond 70 weeks of maternal age. Therefore, chromosome aberration rate was affected by maternal age due to ovulated oocytes state. However, the amount of telomeric DNA on embryonic cells did not differ significantly with maternal age. Thus, maternal age does not affects telomere quantity in their embryos due to cellular reprograming at early embryonic stage after fertilization.