• 제목/요약/키워드: aging stability

검색결과 372건 처리시간 0.027초

Phase Change of Precipitates and Age Hardening in Rapidly Solidified Mg-Zn-Ca Base Alloys

  • Park Won-Wook;You Bong-Sun
    • 한국분말재료학회지
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    • 제12권4호
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    • pp.303-308
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    • 2005
  • Various kinds of Mg-Zn-Ca base alloys were rapidly quenched via melt spinning process. The meltspun ternary and quaternary alloy ribbons were heat-treated, and then the effects of additional elements on age hardening behavior and phase change of precipitates were investigated using Vickers hardness tester, XRD, and TEM equipped with EDS system. In ternary alloys, age hardening was mostly due to the distribution of $Mg_6Ca_2Zn_3$ and $Mg_2Ca$. The stable phases of precipitates were varied according to the aging temperature and the alloy composition. With the increase of Ca content, $Mg_2Ca$ precipitates were detected more than $Mg_6Ca_2Zn_3$ precipitates. In quaternary alloys, the precipitates taken from Mg-Zn-Ca-Co were identified as new quaternary phase, whereas those taken from Mg-Zn-Ca-Zr as MgZnCa containing Zr. In general, the ternary alloy showed higher peak hardness and thermal stability than the quaternary considering the total amounts of the solutes. It implies that the structure of precipitate should be controlled to have the coherent interface with the Mg matrix.

Intravenous administration of piceatannol, an arginase inhibitor, improves endothelial dysfunction in aged mice

  • Nguyen, Minh Cong;Ryoo, Sungwoo
    • The Korean Journal of Physiology and Pharmacology
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    • 제21권1호
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    • pp.83-90
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    • 2017
  • Advanced age is one of the risk factors for vascular diseases that are mainly caused by impaired nitric oxide (NO) production. It has been demonstrated that endothelial arginase constrains the activity of endothelial nitric oxide synthase (eNOS) and limits NO generation. Hence, arginase inhibition is suggested to be vasoprotective in aging. In this study, we examined the effects of intravenous injection of Piceatannol, an arginase inhibitor, on aged mice. Our results show that Piceatannol administration reduced the blood pressure in aged mice by inhibiting arginase activity, which was associated with NO production and reactive oxygen species generation. In addition, Piceatannol administration recovered $Ca^{2+}$/calmodulin-dependent protein kinase II phosphorylation, eNOS phosphorylation and eNOS dimer stability in the aged mice. The improved NO signaling was shown to be effective in attenuating the phenylephrine-dependent contractile response and in enhancing the acetylcholine-dependent vasorelaxation response in aortic rings from the aged mice. These data suggest Piceatannol as a potential treatment for vascular disease.

졸겔법에 의해 제작된 강유전체 BST막의 기계.화학적인 연마 특성 (Chemical Mechanical Polishing (CMP) Characteristics of BST Ferroelectric Film by Sol-Gel Method)

  • 서용진;박성우
    • 대한전기학회논문지:전기물성ㆍ응용부문C
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    • 제53권3호
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    • pp.128-132
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    • 2004
  • The perovskite ferroelectric materials of the PZT, SBT and BST series will attract much attention for application to ULSI devices. Among these materials, the BST ($Ba_0.6$$Sr_0.4$/$TiO_3$) is widely considered the most promising for use as an insulator in the capacitors of DRAMS beyond 1 Gbit and high density FRAMS. Especially, BST thin films have a good thermal-chemical stability, insulating effect and variety of Phases. However, BST thin films have problems of the aging effect and mismatch between the BST thin film and electrode. Also, due to the high defect density and surface roughness at grain boundarys and in the grains, which degrades the device performances. In order to overcome these weakness, we first applied the chemical mechanical polishing (CMP) process to the polishing of ferroelectric film in order to obtain a good planarity of electrode/ferroelectric film interface. BST ferroelectric film was fabricated by the sol-gel method. And then, we compared the surface characteristics before and after CMP process of BST films. We expect that our results will be useful promise of global planarization for FRAM application in the near future.

염무-열 반복 열화에 따른 실리콘 고무의 표면열화특성변화 (The change of surface degradation properties of silicone rubber for salt fog)

  • 오태승;이청;박수길;류부형
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2001년도 하계학술대회 논문집
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    • pp.886-889
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    • 2001
  • Silicone rubber is being used for the housing material of outdoor high voltage insulators such as composite insulator, bushing, surge arrestor and cable terminator because of good tracking and erosion resistance, good hydrophobicity and recovery of hydrophobicity and chemical stability. But, the leakge current occurs on surface of the composite polymeric insulation materials when the insulator is used for a long time with severe contaminative condition and it can lead the contamination flashover. So the leakage current is important to estimate the condition of the silicone rubber surface. In this paper, aging characteristics of silicone rubber used for outdoor insulation have been hydrophobicity of silicone rubber in salt fog chamber with average leakage current monitoring for observing the transformation of surface degradation properties of silicone rubber with different ATH(alumina trihydrate, A1$_2$O$_3$$.$3H$_2$O) filler contents. The experimental results show that a higher peak leakage current and to raise a long time for tracking with increasing amount of ATH by the salt fog and heat recycle ageing.

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Ceramic PTC thermistor의 금속접촉저항과 입계전위장벽 (Analysis on Metal Contact Resistance and Grain Boundary Barrier Height of Ceramic PTC Thermistor)

  • 전용우;임병재;홍상진;소대화
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2006년도 추계학술대회 논문집 Vol.19
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    • pp.235-236
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    • 2006
  • The contact resistance and grain boundary potential barrier of ceramic $BaTiO_3$ PTCR were investigated. The electroless plated Ni, evaporated Al, and Ag paste were chosen as electrode materials of PTCR device for comparison analysis before and after heat treatment. The contact resistance of electrode were measured by electrometer (dc), digital multimeter (dc), and LCR meter (ac). In the case of Al electroded samples, the heat treatment and protective oxide layer had high resistance and effect on the stability of PTCR effect against contact resistance degradation, but the Ag-paste had comparably high contact resistance before heat treatment and decreased after heat treatment with safe. On the other hand, the samples with electroless plated Ni electrode had good properties of contact resistance against aging.

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고령사회 노인주거지원정책에 관한 연구 (A Study of Elderly Residing Support Policy in Advanced Age Society)

  • 신화경;이준민
    • 가정과삶의질연구
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    • 제26권5호
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    • pp.15-25
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    • 2008
  • By population graying, elderly residing problem is risen by social problem. Specially, because residing is occupying many parts in psychological sentimentalize stability of elderly senescence, it is misgovernment that suitable countermeasure is pressing hereupon with governmental interest so that elderly age may can inhabit to suitable residing space. The purposes of this research used content analysis method about elderly residing support policy laying stress on data of elderly residing support policy connection literature, virtue research etc.. and research result is as following ; First, as elderly residing connection equipment is permitted by common people subject operation in government burden gradually in van abroad including our country, supply of elderly equipment is spreading. Second, support about elderly dependent is introducing house priority supply system to financial favors benefit and income tax exemption, aged parents supporter being increasing. Third, through reconstruction and so on of house, real elderly's ashes are developing by support policy. Also, is administering elderly residing support policy by total service that can support elderly aging in place.

노인의 스트레스 대처과정에 대한 근거 이론적 접근 (Stress Coping Process in Elderly People: Grounded Theory Approach)

  • 김애경
    • 기본간호학회지
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    • 제10권3호
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    • pp.345-353
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    • 2003
  • Purpose: The purpose of this study was to explore the stress-coping process used by elderly people. Method: This study was based on the grounded theory methodology of Strauss & Corbin. The participants were 15 elders selected by theoretical sampling. Over a period of 3 months, in-depth interviews using audiotape recording were used to collect the data. The data were analyzed simultaneously by a constant comparative method in which new data were continuously coded in categories and properties according to Strauss and Corbin's methodology, Result: Stress in elderly people is caused by illness, family conflict, and loss of economic power. Stress occurred in connection with aging and limitation of social activity. The central incidents for stress were fear, alienation and anxiety. It was found that action/interactional strategies of stress-coping behavior were related to social support and mobility disorders. Action/interactional strategies to stress-coping in elderly people were dependent on medical treatment, mind control, participation of social activity, and renunciation of offensive behavior. Stress-coping in elderly people resulted in stability or instability in body and mind. Conclusion: It is suggested that the results of this study may contribute to the development stress-coping strategies for elderly people. There is need to develop social support systems and a positive environment to avoid negative coping strategies.

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(n,k) 클러스터 웹서버 시스템의 작업전이를 고려한 소프트웨어 재활기법의 가용도 분석 (Availability Analysis of (n,k) Cluster Web Server System using Software Rejuvenation Method over Switchover)

  • 강창훈
    • 한국컴퓨터산업학회논문지
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    • 제3권2호
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    • pp.227-234
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    • 2002
  • 클러스터 웹서버 시스템에서는 다수 서버의 장애로 인해 발생하는 가용도 저하 문제와 소프트웨어의 노화로 인하여 높은 성능과 가용도를 제공하기 쉽지 않다. 본 연구에서는 n대의 주 서버와 k대의 여분서버로 구성되는 클러스터 웹 서버 시스템에 성능과 작업전이 시간을 고려한 소프트웨어 재활 모델을 제시하였고 다양한 시스템 운영 파라미터에 기초하여 소프트웨어의 재활정책에 대한 평가를 위해 평형 상태에서의 확률, 가용도, 손실비용 등을 계산하였다. 수학적 분석을 통해 다양한 시스템 운영 상태에 대한 실험을 통해 검증하였으며, 소프트웨어의 재활 정책에 의한 예방적 결함허용 기법이 시스템의 안정성에 중요한 요소임을 확인하였다.

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상용 디젤엔진용 산화촉매의 배출가스 저감 특성 (Emission Characteristics of Diesel Oxidation Catalysts for a Commercial Diesel Engine)

  • 최병철;이춘희;박희주;정명근;권정민;신병선;김상수
    • 동력기계공학회지
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    • 제6권2호
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    • pp.18-23
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    • 2002
  • Recently, as people pay attention to the environmental pollution, the emission of diesel engine has become a serious problem. Diesel Oxidation Catalysts(DOC) were experimentally investigated for the purification of pollutants exhaust emission from the diesel engine. In this study, the conversion efficiency of exhaust gas was investigated with various washcoat materials of the DOC. It was formed that CO conversion efficiency depended on temperature, but THC conversion was dominated by temperature and space velocity. Conversion efficiency of THC and CO increased with the addition of ZSM-5 in the washcoat, whereas these conversion efficiency decreased by adding Nd and Ba additives. $V_2O_5$ additive had the thermal stability for high temperature. Thermal durability of the catalyst was improved as increase of $V_2O_5$ additive.

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DNA damage to human genetic disorders with neurodevelopmental defects

  • Lee, Youngsoo;Choi, Inseo;Kim, Jusik;Kim, Keeeun
    • Journal of Genetic Medicine
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    • 제13권1호
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    • pp.1-13
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    • 2016
  • Although some mutations are beneficial and are the driving force behind evolution, it is important to maintain DNA integrity and stability because it contains genetic information. However, in the oxygen-rich environment we live in, the DNA molecule is under constant threat from endogenous or exogenous insults. DNA damage could trigger the DNA damage response (DDR), which involves DNA repair, the regulation of cell cycle checkpoints, and the induction of programmed cell death or senescence. Dysregulation of these physiological responses to DNA damage causes developmental defects, neurological defects, premature aging, infertility, immune system defects, and tumors in humans. Some human syndromes are characterized by unique neurological phenotypes including microcephaly, mental retardation, ataxia, neurodegeneration, and neuropathy, suggesting a direct link between genomic instability resulting from defective DDR and neuropathology. In this review, rare human genetic disorders related to abnormal DDR and damage repair with neural defects will be discussed.