• 디지털융복합연구
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• 제15권3호
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• pp.1-7
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• 2017

한국사회는 2000년 이후 사회서비스 수요의 급격한 증가에 대한 대응으로 사회서비스를 확대, 실시하였고, 현재까지 이용자의 다양한 욕구를 파악하고 충족하기 위한 서비스를 개발해 왔다. 그동안 사회서비스는 가치재로서 준공공재적 성격으로 인하여 민간영역에서 다양하게 확대되어 오는데 한계를 보여주었다. 이에 본 논문은 6대광역시에서 시행하고 있는 사회서비스 중 아동대상사회서비스와 노인대상사회서비스를 중점으로 분석하여, 현 제공되고 있는 사회서비스의 문제점을 파악하고 앞으로의 정책방향을 제시하고자 하였다. 프로그램 분석을 위해 한국보건복지정보개발원, 6대 광역시 시 도 사회서비스지원단 등의 사회서비스 프로그램을 영역별로 표집하여 분석하였다. 프로그램 분석 결과 사회서비스 프로그램 영역의 다양화, 서비스제공인력의 전문화, 지역사회특수성 반영, 서비스 정보 접근성 확대 등의 발전방향이 제시되었다. 또한 개선방안으로는 프로그램 결정과정에서의 이용자 참여 확대 및 서비스 공급자간 네트워크 구축이 필요함이 제시되었다.

• Journal of Ginseng Research
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• 제36권1호
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• pp.68-77
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• 2012

In this study, we investigated the protective effects of processed Panax ginseng, sun ginseng (SG) against the UVB-irradiation on epidermal keratinocytes and dermal fibroblasts. Pretreatment of SG in HaCaT keratinocytes and human dermal fibroblasts reduced UVB-induced cell damage as seen by reduced lactate dehydrogenase release. We also found that SG restored the UVB-induced decrease in anti-apoptotic gene expression (bcl-2 and bcl-xL) in these cells, indicating that SG has an anti-apoptotic effect and thus can protect cells from cell death caused by strong UVB radiation. In addition, SG inhibited the excessive expression of c-jun and c-fos gene by the UVB in HeCaT cells and human dermal fibroblasts. We also demonstrated that SG may exert an anti-inflammatory activity by reducing the nitric oxide production and inducible nitric oxide synthase mRNA synthesis in HaCaT keratinocytes and human dermal fibroblasts. This was further supported by its inhibitory effects on the elevated cyclooxygenase-2 and tumor necrosis factor-${\alpha}$ transcription which was induced by UVB-irradiation in HaCaT cells. In addition, SG may have anti-aging property in terms of induction of procollagen gene expression and inhibition of the matrix metalloprotease-1 gene expression caused by UVB-exposure. These findings suggest that SG can be a potential agent that may protect against the dermal cell damage caused by UVB.

• 한국통신학회논문지
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• 제36권4B호
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• pp.322-331
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• 2011

최근 스마트폰의 확산과 ICT 기술의 발달은 언제 어디서나 유연하게 근무할 수 있는 스마트워킹 여건을 성숙시키고 있다. 본 연구는 중소기업의 업무혁신을 위한 스마트워킹의 의미를 분석하고 이에 대한 구성원들의 의견을 반영, 사회, 경제적 파급효과를 실증적으로 분석하였다. 분석결과 중소기업 종사자의 56.9%가 스마트워킹이 필요하다는 응답을 보였으며, 이용의향에 있어서 60.1%가 긍정적인 평가를 나타냈다. 이에 따른 중소기업 스마트워킹 연관 시장규모를 추정해 보면 연평균 성장율(CAGR)은 17.5% 수준으로, 2010년 0.81조원에서 2014년까지 1.54조원으로 규모가 확대될 것으로 전망되었고, 2014년까지 누적 일자리 38만 개를 창출할 것으로 분석되었다. 본 연구는 중소기업의 Renovation을 통한 경쟁력 강화를 위해 스마트워킹을 도입하고 국가 산업적 측면에서 대-중소기업 동반성장을 위한 중요 실행과제로서 일하는 방식의 혁신이 필요한 근거를 제시한다.

• 대한지역사회영양학회지
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• 제5권2호
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• pp.172-184
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• 2000

To establish a basic cohort which can survey the nutrient and food intake related to the health status of the middle and old-aged vertically, a longitudinal survey of 110 adults over forty years old was conducted three times in Chon-ju city over 5 years (1994-1999), and the influences of health status by changes in their nutrient and food intake were examined in this study. The results were as follows ; The number of subjects was 110(43 man, 67 women), 10.0% in their forties, 28.2% in their fifties, 45.4% in their sixties 6.4% over seventy, and their average age was 61.4. There were decrease of height about 1cm , increase of body fat % and few changes of BMI during the testing period. As the subjects were aging, the percentage of anemia increased, but averages of blood pressure and blood glucose(men : 91.8mg/㎗, women : 90.3mg/㎗) were constant. Total cholesterol increased from 196.7mg/㎗ to 212.6mg/㎗(P 0.05) over five years, and the numerical values for women were higher than that of men. In many cases, lack of nutrient intake was shown, as compared with the Recommended Dietary allowance(RDA) especially calcium and vitamin A(71.7%, 64.9% of RDA). Grains intake showed a tendency to decrease(P 0.01). On the contrary, fruit intake showed a tendency to increase(P 0.001). On whole meal, plant foods were 85.1% and animal foods were 14.9%. As dietary factors influencing health status were investigated, blood glucose was influenced by vitamin B$_2$, potatoes and triglyceride, DBP and SBP were affected by vitamin B$_1$, vitamin C, legumes, fishes, triglyceride and age. Total cholesterol was under the influence of triglyceride, milk, seeds and fat. BMI was influenced by iron, SBP, animal food, and age.

• 한국의류학회지
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• 제31권4호
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• pp.584-593
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• 2007

Recently, the growing of the aging population by medical and science development, silver consumers were became new consumption market. The purposes of this study were to investigate the effects of service quality on consumer satisfaction and repurchase intention in the apparel store and hairdressing shop. Data were obtained from 853 women in the 50's and 60's who living in Busan. Data were analyzed by frequency analysis, factor analysis, Cronbach's alpha, 1-test, and path analysis using SPSS WIN 12.0. The results of the study were as follows: First, service qualities of apparel store were composed of Personal Service, Facilities Service, Product Service, and Policy Service. Service quality of hairdressing shop were consisted of Personal Service, Facilities Service, Skill Service, and Policy Service. Second, repurchasing intention was differently influenced by perceived store service quality and consumer satisfaction when purchasing apparel products and hairdressing services. Salesperson or hairdresser was the most important variable for silver consumers' satisfaction, which influenced the repurchase intention of apparels or hairdressing services. This research extends a domain of fashion market research from the product to the service. Additionally, this study provides an insight into silver fashion marketers and retailers for developing market strategies for silver common. Implications are drawn for the information useful to consumer behavior researchers and retailers of the silver fashion market.

• 한국실내디자인학회논문집
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• 제26권1호
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• pp.25-32
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• 2017

As the elderly population increases rapidly, existing houses many elderly reside are under poor conditions that they work as a factor to impede on the independent living of elderly people. Thus, improving existing housing environment to suit the needs of elderly life has been required. Academics has been continuously researched on the field considering the importance of elderly housing modification and the importance on the research of this field is projected to be greater with the coming of aging society. Hence, this study has a purpose on analyzing trends of previous studies related to housing modification for the elderly published in Korean academic journals in depth. This study is a content analysis study and analyzed the trend of previous studies with academic journal field, purpose of study, research subject, research area, research method, research content as analysis categories. As a result, previous studies was published the most in natural science academic journals and main stream of research was to suggest direction of housing modification by conducting surveys on actual conditions and needs of single elderly families and to suggest improving the directions of policies related to modification. On the other hand, empirical studies needed to execute housing modification such as standard and method of housing modification and supporting tools are still at minimal level that researches on this field should be conducted additionally. This study is expected to be used as basis to examine the current state of previous studies on housing modification for the elderly and to seek further research directions.

• 한국산학기술학회논문지
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• 제15권10호
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• pp.6056-6065
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• 2014

본 연구는 한국 도시거주자의 목적 지향성향 척도 개발에 관한 연구이다. 목적지향성향의 개념을 정립하기 위하여 종교적 학문적 연구를 참조하고 기존의 생산성이나 성공적 노화 또는 삶의 질 척도를 검토하였다. 그 결과 설문을 위해 57개의 문항을 작성하였으며 목회자, 신학대학교수, 사회복지사 등의 축조심의를 거쳐 44개 문항으로 예비문항을 만들었다. 이후 응답자로부터의 효과적 설문을 위해 통계전문 교수와 중복조항 제거, 체계적인 연구 모델 수립을 위해 당해 전문 교수의 검토를 통해 문항을 수정하여 최종 27개 문항을 확정하였다. 수도권을 중심으로 설문을 실시하여 380부를 수집한 후 요인분석을 한 결과 측정도구의 타당성을 검증하였으며, "존재의 인지", "자율적 삶", "자기완성", "적극성", "수용성", "경제성" 등 6개의 하위 요인으로 분류되었다. 신뢰도의 경우 Cronbach's ${\alpha}$값이 0.6 이상으로 신뢰할만한 수준이었다.

• Biomolecules & Therapeutics
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• 제25권2호
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• pp.140-148
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• 2017

Hyperlipidemia, which is closely associated with a fatty diet and aging, is commonly observed in the western and aged society. Therefore, a novel therapeutic approach for this disease is critical, and an immunological view has been suggested as a novel strategy, because hyperlipidemia is closely associated with inflammation and immune dysfunction. In this study, the effects of an aqueous extract of Rubus occidentalis (RO) in obese mice were investigated using immunological indexes. The mice were fed a high-fat diet (HFD) to induce hyperlipidemia, which was confirmed by biochemical analysis and examination of the mouse physiology. Two different doses of RO and rosuvastatin, a cholesterol synthesis inhibitor used as a control, were orally administered. Disturbances in immune cellularity as well as lymphocyte proliferation and cytokine production were significantly normalized by oral administration of RO, which also decreased the elevated serum tumor necrosis factor $(TNF)-{\alpha}$ level and total cholesterol. The specific immune-related actions of RO comprised considerable improvement in cytotoxic T cell killing functions and regulation of antibody production to within the normal range. The immunological evidence confirms the significant cholesterol-lowering effect of RO, suggesting its potential as a novel therapeutic agent for hyperlipidemia and associated immune decline.

• Molecules and Cells
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• 제43권1호
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• pp.58-65
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• 2020

Fat mass and obesity-associated (FTO) gene helps to regulate energy homeostasis in mammals by controlling energy expenditure. In addition, FTO functions in the regulation of obesity and adipogenic differentiation; however, a role in osteogenic differentiation is unknown. This study investigated the effects of FTO on osteogenic differentiation of C3H10T1/2 cells and the underlying mechanism. Expression of osteogenic and endoplasmic reticulum (ER) stress markers were characterized by reverse-transcriptase polymerase chain reaction and western blotting. Alkaline phosphatase (ALP) staining was performed to assess ALP activity. BMP2 treatment increased mRNA expression of osteogenic genes and FTO. Overexpression of FTO increased expression of the osteogenic genes distal-less homeobox5 (Dlx5) and runt-related transcription factor 2 (Runx2). Activation of adenosine monophosphate-activated protein kinase (AMPK) increased FTO expression, and there was a positive feedback loop between FTO and p-AMPK. p-AMPK and FTO induced mild ER stress; however, tunicamycin-induced severe ER stress suppressed FTO expression and AMPK activation. In summary, FTO induces osteogenic differentiation of C3H10T1/2 cells upon BMP2 treatment by inducing mild ER stress via a positive feedback loop with p-AMPK. FTO expression and AMPK activation induce mild ER stress. By contrast, severe ER stress inhibits osteogenic differentiation by suppressing FTO expression and AMPK activation.

• Journal of Nutrition and Health
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• 제35권10호
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• pp.1060-1069
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• 2002

High insulin level is known to be a risk factor of coronary heart disease. High insulin level with normal glycemic control is known to be an indicator for insulin resistance. This study was aimed to find out the influencing factors for the fasting serum insulin levels in elderly females with normal glycemic control. One hundred thirty-eight older females aged over 60 years without diabetes medication and high blood HBA1c level were examined on the serum fasting insulin concentration, anthropometry and asked about nutrient intake and exercise habits. The elderly were categorized into 3 group according to the fasting insulin level. The high insulin group was in a state of hyperinsulinemia. Except vitamin C, the nutrient intakes showed no difference according to fasting serum insulin level. But the intakes of calorie and protein per kg body weight were significantly lower in the high insulin group. The intakes of most nutrients except vitamin B$_1$, C and niacin were lower than the korean RDA in all the insulin group. Especially, the intakes of vitamin B$_1$ and Ca were below 75% of the korean RDA. Weight, BMI, body fat percent, body fat mass and fat-free mass, circumferences of waist and hip, WHR of elderly females were significantly higher in the group with the highest insulin level. The body fat percent in the highest insulin group was 35.8%. showing a state of obesity. The high insulin group showed higher proportion of low exercise frequencies per week and short exercise duration. Therefore, the mean energy expenditure for exercise were lower in this group, showing a state of very low exercise activity. Age and waist circumference in elderly females could explain to the 14.5% variances of the fasting insulin level according to multiple stepwise regression. It can be concluded that aging and central body fat deposition influence independently the serum fasting insulin level in elderly females with normal glucose level.