• 한국건설관리학회논문집
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• 제16권3호
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• pp.24-35
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• 2015

향후 교육시설의 노후화 관리는 단편적인 개 수공사가 아닌 안전하고 쾌적한 교육환경을 목적으로 하는 시설물의 기능을 고려한 통합적인 서비스 관점에서 이루어져야 한다. 이를 위해 현행 유지관리에서 주류를 이루고 있는 편향된 성능기반 관점의 한계성을 인지하고 시설물이 제공해야 하는 유지관리 서비스의 기능과 속성을 반영한 유지관리 체계를 구축하여야 한다. 따라서 본 연구는 교육시설물에서 제공하는 시설물 서비스 기능의 적절한 평가를 위해 서비스 수준 인지에 영향을 미치는 유지관리 항목들을 도출하고, 이를 적절한 범주로 설정하여 향후 지속적이고 효율적인 유지관리 체계를 구축하기 위한 기초자료로 활용하고자 한다. 이를 위하여 주요 유지관리 범주별 영향요인을 측정하기 위한 설명변수가 제시되었고, 그 타당성을 확인하기 위하여 전문가들을 대상으로 수행된 설문에 대해서 적절한 통계적 검증을 수행하였다.

• Environmental Analysis Health and Toxicology
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• 제25권4호
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• pp.295-306
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• 2010

Objectives : This study was undertaken to examine the metabolomic changes due to gender and diurnal variation at sampling time and to identify an appropriate time point for urine sampling in epidemiologic studies using metabolomic profiles. Methods : Urine samples were collected twice a day (morning and afternoon) from 20 healthy Korean adults after fasting for 8 hours. The metabolomic assay was investigated using $^1H$ NMR spectroscopy coupled with the principal components analysis (PCA) and partial least squares discriminant analysis (PLS-DA). The metabolites responsible for differentiation between groups were identified through the loading plot of PLS-DA and quantified using Chenomx NMR Suite with a 600 MHz library. Results : Metabolites responsible for differentiation in gender and sampling time were creatinine, trimethyl anine oxide (TMAO), hippurate, mannitol, citrate and acetoacetate. Dimethylamine showed difference only as a factor of diurnal time. The level of creatinine was higher in men compared to women, and the levels of citrate, TMAO, hippurate, mannitol, and acetoacetate were higher in women compared to men. The levels of creatinine, TMAO, hippurate, dimethylamine and mannitol were higher in the morning rather than the afternoon while those of citrate and acetoacetate were higher in the afternoon rather than the morning. Conclusions : Since urinary metabolomic profiles varied by gender and diurnal cycle, urine sampling should be performed at the same time point for all participants in epidemiologic studies using metabolomic profiles.

• 대한한방내과학회지
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• 제25권4호
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• pp.105-116
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• 2004

Objective : In this study, we used the aged bilateral common carotid artery occlusion (BCAO) rats were used to measure the effect of Bupleuri Radix (Si-Ho) on the brain ischemic injury, because aging is an important factor in storke, Method : The brian ischemic injury was induced by temporary closing of carotids on both sides in a low blood pressure state. Bupleuri Radix (Si-Ho) was orally administered in 18-month-old BCAO rats. Result : The Ischemic Damaged Hippocampus and HSP expression were analyzed by the immunohistochemical staining and the result were as follows: 1. The low numbers of pyramid cells in the hippocampus CA1 area for the ischemically injured experimental group rose to numbers simillar to those of the control group. 2. The thin neuronal cell layer in the hippocampus CA1 area for the ischemically injured experimental group returned to thickness simillar to those of the control group. 3. The normalized optical density of HSP70 expression was suppressed in CA2, DG and CA1 expression was significantly suppressed in the experimental group compared to the control group. Conclusion : These results suggested that Bupleuri Radix (Si-Ho) has a neuroprotective effect by reducing neural cell injury in the initial ischemic state.

• 대한기계학회논문집A
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• 제40권3호
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• pp.245-252
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• 2016

본 논문은 벤드(bend)부의 노후 문제를 경감시키기 위한 대안으로 폼패드를 없앤 이중보온관의 형상 설계를 제안하였다. 전 관경에 대해 유한요소해석을 수행하였으며, 이를 토대로 전단제어링 형상을 결정하였다. 제안된 전단제어링 사양 강화이형관에 대한 현장 시공 시험은 진행하였으며, 온도와 응력 데이터를 취득 및 분석하였다. 강화이형관의 제작과 현장 시범시공을 통하여 강화이형관이 폼패드를 시공하지 않으면서도 강관의 열응력이 허용치 기준내에 있음을 확인하였다. 특히 보온재의 전단강도가 강화되어 폼패드를 적용한 기존 벤드보다 낮은 최대 전단응력이 발생함을 확인함으로써, 강화이형관 적용에 따른 구조 안전성 향상 효과를 확인하였다.

• Journal of Preventive Medicine and Public Health
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• 제38권1호
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• pp.16-24
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• 2005

Objectives : To help develop strategies to cope with the changes arising from the rapid aging process by predicting the determining factors of intention to actual use of the charged long-term care services for elderly as perceived by the middle aged who play the major role of supports. Methods : Subjects were the parents (men 177, women 507) in their 40s of the students selected from a university of Busan city. A questionnaire survey was conducted for 4 weeks in October 2003 about the knowledge for long-term care service, the intention of actual use, and the preferences about the type of service suppliers. Data analysis was performed with frequency, chi-square test, and t-test using SPSS program (ver 10.0K), along with data mining using decision tree of Enterprise Miner V8.2 by SAS. Results : About half of the subjects (53.7%) had the actual experiences of elderly supports. Intentions to use the charged services were relatively high in home visiting nursing care service (40.1%) and long-term care facilities service (40.4%), and were influenced by previous knowledge about the services. The intentions were stronger in women, those with higher education, and those with greater income levels. Actual elderly supports were mostly (80%) done by women, and the perceived burdens for the supports were bigger in women and those of lower socioeconomic level. Desired charges were about 10,000 won for the bath service, 20,000 won for the rests services per day, and about 500,000 won for the long-term care facilities service per month. From the result of decision tree analysis, the job professionalism was the most important determining factor of intention to actual use of the services with validation as $63{\sim}71%$. Health and welfare mixed type facilities were preferred, and the most important consideration was the level of professionalism. Conclusions : Intention to actual use of the charged services was largely determined by the aspects of time and cost. Polices to increase the number of service suppliers and to decrease the burdens perceived by actual supporters were strongly recommended.

• Natural Product Sciences
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• 제22권3호
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• pp.201-208
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• 2016

Here in this study, we investigated the lifespan-extending effect and underlying mechanism of methanolic extract of Moringa olelifa leaves (MML) using Caenorhabditis elegans (C. elegans) model system. To define the longevity properties of MML we conducted lifespan assay and MML showed significant increase in lifespan under normal culture condition. In addition, MML elevated stress tolerance of C. elegans to endure against thermal, oxidative and osmotic stress conditions. Our data also revealed that increased activities of antioxidant enzymes and expressions of stress resistance proteins were attributed to MML-mediated enhanced stress resistance. We further investigated the involvement of MML on the aging-related factors such as growth, food intake, fertility, and motility. Interestingly, MML significantly reduced growth and egg-laying, suggesting these factors were closely linked with MML-mediated longevity. We also observed the movement of aged worms to estimate the effects of MML on the health span. Herein, MML efficiently elevated motility of aged worms, indicating MML may affect health span as well as lifespan. Our genetic analysis using knockout mutants showed that lifespan-extension activity of MML was interconnected with several genes such as skn-1, sir-2.1, daf-2, age-1 and daf-16. Based on these results, we could conclude that MML prolongs the lifespan of worms via activation of SKN-1 and SIR-2.1 and inhibition of insulin/IGF pathway, followed by DAF-16 activation.

• 농촌계획
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• 제19권1호
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• pp.109-122
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• 2013

The rapid rural urban migration and aging has generated an over-depopulation problems in rural areas since the 1980s. The purpose of this study constructs the marginal size of rural over-depopulated village through the analysis of the residential disparities such as farmer's ratio, basic life service accessibility, and levels of social and economic factors for each village community. This marginal scale could support evaluating diverse rural policies, which have been planned to apply to the rural development programs at the village level. The major challenges for over-depopulated villages are the lack of basic facilities, production infrastructures and inactive communities in the village. Therefore, the quantitative analysis of rural residential disparities according to rural village scale can provide the criteria for rural over-depopulated villages. We utilized Korea Agricultural Survey Data(2010) including specific residential condition of village level. The present study adopt multinomial-logit model for quantitative analysis of different village scales and decomposition techniques to separate the direct effect by the village scale factor from the endowment effects by regional or area characteristics, and residual effect by unknown factors. The present study found that the minimum scale of a rural over-depopulated village was 40 and 60 houses for the respective conditions of farmer's ratios less than 50% and greater than 75%. It was concluded based on the study findings that threshold scale could support evaluating the diverse rural policies, which have been planned to apply to the rural development programs at the village level.

• 동의생리병리학회지
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• 제18권1호
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• pp.93-100
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• 2004

This study was carried out for analyzing pathological and epidemiological factors of osteoporosis and doing pilot test using trial compounds of tuna bone and oriental herbs based on the factors. Osteoporosis is originated from osteoblast, osteoclast, organic and inorganic factors etc. Therefore the pathology of osteoporosis is not simple because the cytokine, growth factors and hormones of the components are various a lot. Taking a view of epidemiological factors of type I osteoporosis, ageㆍmenarcheㆍcholesterolㆍBMI etc. have definite relation to them. So we can approach to aging or consumptive disease in oriental medicine, specifically differential diagnosis of blood depletion with deficiency of qi, deficiency of kidney, deficiency of yin, bony weakness etc. And it should be considered together with rules for maintaining good health or habit concomitantly. Therefore IL1ㆍ6 or TNF αㆍβ are generally used as molecular biological index for osteoblast and osteoclast because the most important index is bone mineral density and strength, but the factors like collagen and noncollagen protein must be accounted as biomarkers. Trial compounds generally showed favorable effects on accompanying subjective symptoms of osteoporosis in the pilot test for menopausal woman. But if she didn't have specific symptoms of osteoporosis there wasn't any specific change. And osteocalcin was increased in case of being under standard level, but wasn't changed in case of normal level. Therefore these trial compounds can be used as a funcdonal diet for type I osteoporotic patients or preventive measures.

• 한국농공학회논문집
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• 제62권1호
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• pp.105-115
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• 2020

With the decrease of the agricultural population in Korea, the workers who is vulnerable to labor are increasing in agricultural industry because of aging, feminization of population. They are exposed in poor working environment with higher temperature and concentrations of dust, gas. Higher concentration of harmful gas and dust can cause chronic and acute disease to workers depending on exposure intensity and frequency. In order to improve the working environment in the livestock facilities, It is important to secure monitoring data of the thermal environment and the concentration of harmful gases and fine dust. Multi-point measurement was performed to analyze the regional environmental conditions in the pig rooms. When analyzing the working environment, video monitoring was conducted to analyze the concentration changes of ammonia, hydrogen sulfide and fine dust according to worker movement and work type. Ammonia and hydrogen sulfide monitoring result showed 1.5~2 times higher concentrations than other work when working in the pigs living zone, and 2~4 times higher than other work when working to increase the activity of pigs. In the case of fine dust, the result was 1.3 times higher than the worker's exposure standard in a specific work. The concentrations of gases and dusts from pig farms are not of concern for acute poisoning in normal work, but there is a risk of chronic respiratory disease if they are continuously exposed. Accordingly, there is a need for development of work environment monitoring device tailored to workers and preparation of alternatives.

• 대한물리치료과학회지
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• 제21권1호
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• pp.37-43
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• 2014

Background : The purpose of this study is to verify the type of influence on the skin color according to the photoaging symptoms depending on the degree of external activities among the factors that influence the skin due to UV exposure and to obtain the basic study data on the physical therapy of the skin. Methods : In this study, in order to investigate the type of influence on the skin color according to the photoaging symptoms when the body is exposed to the UV rays having various effects on our body, a study was conducted using questionnaires and skin color measurement tool targeting 20 male college soccer students with many external activities and the senior high school students who has relatively less external activities due to the preparation for college entrance. The skin color was measured and the results were compared. Result : In the test group having relatively higher external activities, while they had less use of the sunscreen, they had more degree of UV exposure, and for the recognition of ultraviolet hazard, more were aware that it was harmful. In addition, in the skin color measurement test conducted targeting the son and the father in order to investigate the association between the skin color and the genetic factors, the experimental group showed a significant difference(p<.05) but the control group did not show any significant difference(p>.05). Conclusion : Based on such study results, the UV exposure time and the use of sunscreen are thought to be an important factor in the skin care.