• 제목/요약/키워드: ages

검색결과 5,475건 처리시간 0.031초

한국약용식물의 최종당화산물 생성저해활성 검색 (II) (Screening of Korean Herbal Medicines with Inhibitory Activity on Advanced Glycation End Products (AGEs) Formation (II))

  • 이윤미;김영숙;김종민;장대식;김주환;유정림;김진숙
    • 생약학회지
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    • 제39권3호
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    • pp.223-227
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    • 2008
  • Advanced glycation end products (AGEs) contribute to the progression of micro and macrovsacular complication of diabetes and therefore present a promising target for therapeutic agents. In this study, 40 Korean herbal medicines have been investigated with an in vitro evaluation system using AGEs inhibitory activity. Of these, 21 herbal medicines $(IC_{50}<50{\mu}g/ml)$ exhibited an inhibitory activity against AGEs formation compared with anminoguanidine $(IC_{50}=72.12{\mu}g/ml)$. Particularly, 7 herbal medicines, Actinidia arguta (root and stem), Crataegus pinnatifida (twig), Camellia japonica (whole), Kalopanax pictus (bark), Lagerstroemia indica (leaf-stem), Reynoutria sachalinensis (root) showed more potent inhibitory activity (approximately 3-10 fold) than the positive control aminoguanidine.

증평-덕평 지역 중부 옥천변성대에 분포하는 이질 편암의 K-Ar 흑운모 연대 (K-Ar biotite ages of pelitic schists in the Jeungpyeong-Deokpyeong area, central Ogcheon metamorphic belt, Korea)

  • 조문섭;김인준;김현철;민경원;안중호;장미경개
    • 암석학회지
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    • 제4권2호
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    • pp.178-184
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    • 1995
  • 증평-덕평 지역에서 산출하는 중부 옥천변성대의 13개 이질 편암에서 구한 K-Ar 흑운모 연대는 한 개 시료를 제외하고는 89-213Ma 의 범위에 속한다. 이들 K-Ar 연령은 쥬라기와 백악관 화강암체어 가까와 질수록 체계적으로 감소하는 경향을 보인다. 쥬라기 백악관 화강암체 부근에서 얻은 K-Ar 흑운모연대는 각각 166Ma와 89Ma이다. 따라서 연구 지역의 흑운모 연대는, 트라이아스가 후기 내지 쥬라기 초기의 광역-열 변성작용 이후, 중생대화강암의 관입에 의한 열적 작용 때문에 부분적으로 또는 거의 완전히 재평형되었음을 알 수 있다.

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11∼15세기 중반 기사문화가 중세복식에 미친영향 (An Effect on the Costumes in the Middle Ages of the Culture of Knight from the 11th Century to Middle of the 15th Century)

  • 조현진;김영삼;정흥숙
    • 복식
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    • 제54권4호
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    • pp.27-40
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    • 2004
  • In this thesis, the connectivity between the military culture in the Middle Ages and costumes by researching the effect on the clothing in the Middle Ages of the culture of knight from the 11th century to middle of the 15th century was tried to be recognized. The culture of knight was widely divided into 4 articles - Chivalry, Tournamemt, The equipment of knight, Heraldry - and then researched. The conclusion after researching the influence of the culture of knight upon the clothing in the Middle Age in the above is as follows. Regarding the clothing, the military culture such as the crusader war, armor, and heraldry was popularized over the entire Middle Ages as the military-look style, and regarding the ornament the result of the crusader war caused the introduction of the Eastern civilization and development of the commerce and industry, and also trade, and consequently the ornament became luxurious. Regarding the footwear, when seeing the Gothic shoes, it can be found that it is similar with the knight's shoes made of the metal. As seen in the above, it can be recognized that the culture of knight caused the huge influence upon the whole politics, culture, and society in the Middle Ages as well as upon the costumes.

노안의 근용가입도에 관한 연구 (A Study on Near Addition of Presbyopia)

  • 윤경한
    • 한국안광학회지
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    • 제11권1호
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    • pp.1-5
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    • 2006
  • 본 연구에서는 40세부터 65세까지의 장년층의 노안굴절력과 근용가입도를 조절력 검사방법으로 연구하였다. 그 결과는 다음과 같다. 1. 가입도는 +0.50Dptr에서 +3.50Dptr까지 검출되었다. 2. 40세부터 44세까지는 +1.50.Dptr${\geq}$가입도${\geq}$0.50 Dptr로 검출되었다. 3. 45세부터 50세까지는 +2.00.Dptr${\geq}$가입도${\geq}$1.00 Dptr로 검출되었다. 4. 51세부터 55세까지는 +3.00.Dptr${\geq}$가입도${\geq}$1.50 Dptr로 검출되었다. 5. 56세부터 65세까지는 +3.50.Dptr${\geq}$가입도${\geq}$2.50 Dptr로 검출되었다. 6. 검사대상자중에서 근용안경장용자는 75%로 나타났다.

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선천성 고혈압 쥐의 연령별 뇌조직 중의 모노아민 함량및 MAO 활성 변화 (Age-related Changes of Brain Monoamine Contents and Monoamine Oxidase (MAO) Activities in Spontaneously Hypertensive Rats)

  • 박근희;정혜주;고광호
    • 약학회지
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    • 제29권6호
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    • pp.367-374
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    • 1985
  • The age-related changes of monoamine contents and monoamine oxidase (MAO) activities in the whole brain and blood pressures were measured and compared every week during the ages of 5 weeks to 12 weeks in two types of animals; (1) spontaneously hypertensive rats (SHR) and (2) normotensive Sprague-Dawley rats (NR). Blood pressures in SHR began to rise at the ages of 7 or 8 weeks and were significantly higher thereafter than in NR. Abnormally low MAO activities in the brain of SHR were detected from the ages of 8 weeks. Comparisons were also made between brain monoamine-norepinephrine, dopamine and 5-hydroxytrytamine contents of SHR and those of NR at the same ages throughout the test period. In SHR, none of those monoamine values was consistently higher or lower than in NR during the test period. Protein contents of the brain between SHR and NR were not significantly different at any ages. These observations suggest that the abnormally low MAO activities in SHR brain may be one of the underlying neurological factors for the susceptibilities to hypertension and the deficit of MAO activities may be due to the changes in properties rather than in amount of this enzyme.

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Incremental extended finite element method for thermal cracking of mass concrete at early ages

  • Zhu, Zhenyang;Zhang, Guoxin;Liu, Yi;Wang, Zhenhong
    • Structural Engineering and Mechanics
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    • 제69권1호
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    • pp.33-42
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    • 2019
  • Thermal cracks are cracks that commonly form at early ages in mass concrete. During the concrete pouring process, the elastic modulus changes continuously. This requires the time domain to be divided into several steps in order to solve for the temperature, stress, and displacement of the concrete. Numerical simulations of thermal crack propagation in concrete are more difficult at early ages. To solve this problem, this study divides crack propagation in concrete at early ages into two cases: the case in which cracks do not propagate but the elastic modulus of the concrete changes and the case in which cracks propagate at a certain time. This paper provides computational models for these two cases by integrating the characteristics of the extended finite element algorithm, compiles the corresponding computational programs, and verifies the accuracy of the proposed model using numerical comparisons. The model presented in this paper has the advantages of high computational accuracy and stable results in resolving thermal cracking and its propagation in concrete at early ages.

서해안 및 남해안의 해안단구 연구와 융기율 (Study on Coastal Terrace and Uplift Rate in the West and South Coasts of South Korea)

  • 박충선;김유홍;남욱현;이광률
    • 한국지형학회지
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    • 제25권4호
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    • pp.49-62
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    • 2018
  • This study tries to reveal uplift rates inferred from relative and absolute ages on coastal terrace in the West and South Coasts of South Korea. Uplift rate from relative ages on Pleistocene coastal terrace in the West Coast rangesfrom approximately 0.059 to 0.282 m/ky, while a range of approximately 0.020~0.385 m/ky is calculated from the South Coast, suggesting that the South Coast shows higher rate than the West Coast. Based on absolute ages on coastal terrace during MIS 5 in the South Coast, on the other hand, the uplift rates 1 and 4 have ranges of approximately 0.042~0.062 m/ky and 0.051~0.087 m/ky, respectively, indicating that uplift rate in the South Coast is one-third to one-fourth to that in the East Coast. No research on absolute ages in West Coast terrace and lack of relative and absolute ages in the West and South Coasts are considered as the limit in this study.

초기재령 콘크리트 슬래브의 처짐 예측 (Mechanical Properties of Reinforced Concrete Slabs at Early Ages)

  • 신성우;유석형;오성진;황동규;박기홍
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2002년도 가을 학술발표회 논문집
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    • pp.397-400
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    • 2002
  • The mechanical properties of concrete such as modulus of elasticity, bond strength and shear strength are proportional to square root of compressive strength. And compressive strength of concrete is developed rapidly at early ages. Thus the relationship between compressive strength and its mechanical properties should be verified because the mechanical properties of early age concrete and hardened concrete are different. In this study, to predict the concrete slab deflection at early ages, modulus of elasticity and effective moment of inertia(Ie) are observed and compared with experimental results.

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HISTORY OF STAR FORMATION OF EARLY TYPE GALAXIES FROM INTEGRATED LIGHT: STELLAR AGES AND ABUNDANCES

  • Schiavon, Ricardo P.
    • 천문학논총
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    • 제25권3호
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    • pp.83-90
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    • 2010
  • I briefly review what has been learned from determinations of mean stellar ages and abundances from integrated light studies of early-type galaxies, and discuss some new questions posed by recent data. A short discussion of spectroscopic ages is presented, but the main focus of this review is on the abundances of Fe, Mg, Ca, N, and C, obtained from comparisons of measurements taken in integrated spectra of galaxies with predictions from stellar population synthesis models.

수학과 미술의 추상성

  • 계영희
    • 한국수학사학회지
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    • 제12권2호
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    • pp.119-133
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    • 1999
  • In this paper, we consider the abstraction of mathematics and arts. In particular, we compare cave arts of Palaeolith stone ages with those of Neolith stone ages and analyze paintings of a child. After the Middle ages, in Renaissance period the new technique, perspective was introduced by painters for the sake of realistic description. We consider the social background of perspective. In 19th century, European society became familiar with the abstraction of mathematics and arts. And we also study the mathematical concepts and the abstract paintings on the basis of the social backgrounds.

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