• Bulletin of the Korean Chemical Society
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• 제33권7호
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• pp.2447-2449
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• 2012

• Bulletin of the Korean Chemical Society
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• 제34권1호
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• pp.246-248
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• 2013

• Bulletin of the Korean Chemical Society
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• 제35권10호
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• pp.3059-3062
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• 2014

Two new butyrolactones, asperphenol A (1) and B (2), together with four known butyrolactones (3-6) were isolated from the fermentation products of an endophytic fungus Aspergillus versicolor. Their structures were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compounds 1-6 were also tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compound 2 exhibited high anti-TMV activity with inhibition rate of 46.7%. The other compounds also exhibited potential anti-TMV activities with inhibition rates in the range of 21.8-28.4%.

• Bulletin of the Korean Chemical Society
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• 제34권11호
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• pp.3257-3260
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• 2013

Two new diphenylethylenes, gramniphenols H and I (1 and 2), together with six known diphenylethylenes (3-8), were isolated from Arundina graminifolia. The structures of 1-8 were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compounds 1 and 2 were evaluated for their cytotoxicity against five human tumor cell lines. Compound 1 showed cytotoxicity against PC3 cells with $IC_{50}$ value of 3.5 ${\mu}M$. Compound 2 showed cytotoxicity against NB4 and PC3 cells with $IC_{50}$ values of 3.6 and 3.8 ${\mu}M$, respectively.

• Bulletin of the Korean Chemical Society
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• 제34권4호
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• pp.1263-1265
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• 2013

• Bulletin of the Korean Chemical Society
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• 제34권10호
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• pp.3013-3016
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• 2013

Two new isoflavanones, (3R) 7,2',4'-trihydroxy-3'-methoxy-5-methoxycarbonyl-isoflavanone (1) and (3R) 7,2'-dihydroxy-3',4'-dimethoxy-5-methoxycarbonyl-isoflavanone (2), together with six known isoflavanones (3-8), were isolated from the stems of Cassia siamea. The structure of 1-8 was elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compounds 1, 2, 5-8 were evaluated for their anti-tobacco mosaic virus (Anti-TMV) activity. The results showed that compounds 1 and 6 showed potential anti-TMV activity with inhibition rates of 24.6% and 26.9%, respectively. Compounds 2, 5, 7, 8 also showed anti-TMV activity with inhibition rates in the range of 11.8-18.6%.

• Bulletin of the Korean Chemical Society
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• 제34권5호
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• pp.1421-1424
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• 2013

Two new isoflavanones, (3R) 5,7,3',4'-tetrahydroxy-2'-methoxyisoflavanone (1) and (3R) 5',8-di-(${\gamma}$,${\gamma}$-dimethylallyl)-2',5-dihydroxyl-4',7-dimethoxyl-isoflavanone (2), were isolated from Uraria clarkei, together with two known compounds dalbergioidin (3), 5,7-dihydroxy-2',4'-dimethoxyisoflavanone (4). The structures involving the absolute configuration of the new compounds were well elucidated by MS, IR, UV, CD, 1D and 2D NMR analyses. Cytotoxicity of the four compounds were assessed, results suggested that compound 2 possessed well cytotoxic activity, against the Hela, K562, and HL60 cell lines with $IC_{50}$ values of 28.0, 40.6 and $35.1{\mu}M$, respectively.

• 한국콘텐츠학회논문지
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• 제21권7호
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• pp.281-290
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• 2021

소방사무의 범위는 지역 화재예방에서 구조 및 구급 업무로 확대되었고, 소방체제는 자치소방체제에서 광역소방체제로 전환되었다, 또한 많은 논란의 대상이었던 소방공무원의 신분은 국가직으로 일원화되었다. 그러나 근본적인 문제가 여전히 미해결의 상태로 남아 있다. 바로 국가직으로 전환된 소방공무원의 자치사무인 소방사무 담당과 자치사무로 평가되는 소방사무의 국가사무로의 전환과 관련된 문제이다. 소방사무의 성격에 관한 논란은 국가와 자치단체 사이의 사무기능 및 배분의 조정에 대한 불분명과 중복성, 그리고 근본적으로 사무와 신분의 체계통일성을 이루지 못한 불완전한 입법에 기인한다. 소방사무는 국방 및 경찰사무와 함께 국가의 존립과 국민의 안녕과 질서를 포함하는 사무로서 국가적 책무가 존재한다. 국민의 생명, 신체 및 재산을 보호하는 국민의 안전과 관련된 소방사무는 국가사무로 이해되어야 한다. 지방자치법 상 지방자치단체는 법률에 다른 규정이 있는 경우 외에는 국가의 존립에 필요한 사무, 전국적으로 통일을 요하는 사무, 전국적 규모의 사무 등 국가사무를 처리할 수 없다고 규정하고 있다. 소방사무는 그와 같은 사무에 해당한다고 보아야 한다. 국민의 안전과 생명에 대한 권리와 그에 대한 보호 의무가 국가의 의무임을 고려한다면 소방공무원의 국가직화의 이유가 근본적으로 단지 처우와 재정의 문제가 아니었음을 유념할 필요가 있다.

• Bulletin of the Korean Chemical Society
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• 제34권3호
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• pp.827-830
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• 2013

Investigation of an organic extract of the fruits Schisandra wilsoniana led to the isolation of two new highly oxygenated nortriterpenoids, named schilancidilactones V-W (1-2). Their structures were elucidated by spectroscopic evidence. Compounds 1-2 feature a double bond between C-7 and C-8 compared with related known nortriterpenoids isolated from the genus Schisandra. Compounds 1 and 2 were tested for their anti-HIV-1 activities and cytotoxicity. The results revealed that compounds 1 and 2 showed moderate anti-HIV-1 activities with $EC_{50}$ 3.05 and 2.87 ${\mu}g/mL$, respectively, and compound 1 showed high cytotoxicity against KB and MDA-MB-231 cell with $IC_{50}$ values of 3.18 and 5.22 ${\mu}M$, respectively.

• Bulletin of the Korean Chemical Society
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• 제33권1호
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• pp.278-280
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• 2012