• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 2000.11b
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• pp.117-123
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• 2000

Using the modified DEM (Discrete Element Method), which we proposed in order to improve the accuracy of the simulation, soil behavior and reaction by lugs of rotating wheel and a soil cutting process by a high speed blade were calculated and compared with experimental data. The DEM is one of computational mechanics, where the object body is supposed as an assembly of small particles called elements and not a continuum as in the case of FEM. We can easily treat some discrete phenomena such as cracking, separating and sliding by the DEM. We had to modify the original mechanical model, which induced too free movement of elements, adding a tension spring, which would display the role of soil adhesion. The results of DEM simulations were successful from both the soil behavior and reaction points of view.

• Proceedings of the Membrane Society of Korea Conference
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• 1998.04a
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• pp.105-109
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• 1998

1. Introduction : In microfiltration the transport, deposition and removal of particles control cake formation on a filter. In this connection a new model on cake formation, based on the wall shear stress, was tested here in comparison with experiments of fine particle slurry under Taylor-vortex flow. The model expresses the deposition process for particles as two first-order steps in series of mass transfer and adhesion, and their removal process as a linear relation to the wall shear stress. This embraces characteristics of both dead-end and crossflow filtration. The correlation resulting from fitting to experimental data represented the experimental data reasonably well. This study will be helpful in analyzing fouling in heat exchangers.

• Archives of Pharmacal Research
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• v.18 no.6
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• pp.376-380
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• 1995

Monocyte adhesion involves specific cell surface receptors, integrins and results in cell differentiation. We have studied expression and regulation of integrin .${\alpha}_5{\beta}_1$ during differntiation of U937 as in vitro model. To determine expression of integrin ${\alpha}_5{\beta}_1$ during differentiation of U937 as in vitro model. To determine expression of integrin ${\alpha}_5{\beta}_1$ genes by RT-PCR (reverse transcription and polymerase chain reaction) method. We determined expression of integrin ${\alpha}_5{\beta}_1$ genes by RT-PCE (reverse transcription and polymerase chain reaction) method. We found that expression of integrin .alpha.5.betha.1 was greatly increased during PMA-induced differentiation of U937 cells and also found that PMA-induced expression of integrin ${\alpha}_5{\beta}_1$ was inhibited by colchicine, microtubule depoly merizing agent. These results indicate that microtubular integrity is associated with expression of integrin. ${\alpha}_5{\beta}_1$ during PMA-induced differentiation of U937 cells.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.137.2-137.2
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• 2003

Dendritic cells (DCs) are known to professional antigen presenting cell (APC). Due to the role as an effective activator of cytotoxic T Lymphocytes by expressing MHC, adhesion and co-stimulatory molecules, DCs are now widely recognized to play an important role in the immune responses to tumors.We investigated the effect of cultured DCs in murine melanoma pulmonary metastasis model. To follow the metastasis protocol, syngenic melanoma cells were inoculated intra-venously into the mouse (B16F10 into the C57BL/6)8 days prior to the first DC injection (1$\times$106 DCs/ mouse, i.p.) and the autologous tumor cell lysate pulsed-DCs were injected as a therapeutic module twice in two weeks. (omitted)

• Proceedings of the Korean Institute of Building Construction Conference
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• 2020.11a
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• pp.192-193
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• 2020

In reinforced concrete adhesion studies, the demolition of the specimen is inevitably involved, and the studies conducted are limited to the macro load-displacement analysis. In order to establish an elaborate model for concrete bonding reinforced rebars, it is necessary to observe the rebar bonding behavior in the in-situ state. In this study, specially manufactured reinforcing bars, micro-UTM and 𝝁-computer tomography (𝝁CT) are used to observe reinforcing bars in the in-situ state. As a result of the monotonic pullout test of the processed reinforcing bar, maximum bond stress were shown to be 16.7MPa, which is slightly higher than the existing 10 to 12 MPa, and then the empty space inside the specimen in which the pullout test was conducted using 𝝁CT was confirmed. Through additional research, the fracture phenomenon of concrete excluding voids will be studied.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2022.04a
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• pp.133-134
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• 2022

This study proposed vision artificial intelligence-based automated supervision technology for external insulation and finishing system, and basic research was conducted for it. The automated supervision technology proposed in this study consists of the object detection model (YOLOv5) and the part that derives necessary information based on the object detection result and then determines whether the external insulation-related adhesion regulations are complied with. As a result of a test, the judgement accuracy of the proposed model showed about 70%. The results of this study are expected to contribute to securing the external insulation quality and further contributing to the realization of energy-saving eco-friendly buildings. As further research, it is necessary to develop a technology that can improve the accuracy of the object detection model by supplementing the number of data for model training and determine additional related regulations such as the adhesive area ratio.

• Journal of Veterinary Clinics
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• v.26 no.6
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• pp.547-555
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• 2009

This study was performed to determine the minimum dose of Poloxamer/Sodium alginate (PX/SA) mixture on preventing intraperitoneal adhesions to evaluate organ toxicity. Twenty five healthy adult mongrel dogs (weighing 4.68${\pm}$1.67 kg) were divided into five experimental groups composed of five dogs respectively; negative control group (NC, non-treated), positive control group (PC, 2% carboxymethyl chitosan solution treated), and experiment 1 group (E1, 0.25 ml PX/SA mixture of abraded area), experiment 2 group (E2, 0.5 ml PX/SA mixture of abraded area), experiment 3 group (E3, 1.0 ml PX/SA mixture of abraded area). Venous blood specimens were collected from all experimental animals for hematologic and biochemical analysis: WBC, fibrinogen, AST, ALT, ALP, BUN and creatinine. The anti-adhesion effect was evaluated using a serosa abrasion model. The denuded ileum was coated with PX/SA mixture, carboxymethyl chitosan solution or neither. The tensile strength of the adhesion site was evaluated with a tensiometer. For histopathological examination, tissue samples of the liver and kidney were collected from all dogs. According to the results, the frequency and tensile strength values for adhesion separation in PX/SA group were significantly lower than those in negative control group (p < 0.05). In E2 group, the tensile strength was significantly decreased in consideration of PX/SA dose. The values of AST, ALT, ALP, BUN and creatinine of the control and the experimental groups showed no statistical differences. No obvious microscopic differences were noted among tissue sections obtained from all groups. The results suggest that PX/SA mixture may be effective on reducing peritoneal adhesion formation in dog and that 0.5 ml PX/SA mixture of abraded area is most effective dose. Moreover, PX/SA mixture was considered not to have toxicity for the liver and the kidney.

• International Journal of Highway Engineering
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• v.17 no.3
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• pp.77-83
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• 2015

PURPOSES : In this study, a fracture-based finite element (FE) model is proposed to evaluate the fracture behavior of fiber-reinforced asphalt (FRA) concrete under various interface conditions. METHODS : A fracture-based FE model was developed to simulate a double-edge notched tension (DENT) test. A cohesive zone model (CZM) and linear viscoelastic model were implemented to model the fracture behavior and viscous behavior of the FRA concrete, respectively. Three models were developed to characterize the behavior of interfacial bonding between the fiber reinforcement and surrounding materials. In the first model, the fracture property of the asphalt concrete was modified to study the effect of fiber reinforcement. In the second model, spring elements were used to simulated the fiber reinforcement. In the third method, bar and spring elements, based on a nonlinear bond-slip model, were used to simulate the fiber reinforcement and interfacial bonding conditions. The performance of the FRA in resisting crack development under various interfacial conditions was evaluated. RESULTS : The elastic modulus of the fibers was not sensitive to the behavior of the FRA in the DENT test before crack initiation. After crack development, the fracture resistance of the FRA was found to have enhanced considerably as the elastic modulus of the fibers increased from 450 MPa to 900 MPa. When the adhesion between the fibers and asphalt concrete was sufficiently high, the fiber reinforcement was effective. It means that the interfacial bonding conditions affect the fracture resistance of the FRA significantly. CONCLUSIONS : The bar/spring element models were more effective in representing the local behavior of the fibers and interfacial bonding than the fracture energy approach. The reinforcement effect is more significant after crack initiation, as the fibers can be pulled out sufficiently. Both the elastic modulus of the fiber reinforcement and the interfacial bonding were significant in controlling crack development in the FRA.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.63 no.8
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• pp.1164-1169
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• 2014

Recently, an interest in a hybrid system combining only the merits of the conventional wheel-rail system and Maglev propulsion system is growing as an alternative to high-speed maglev train. This hybrid-type system is based on wheel-rail method, but it enables to overcome the speed limitation by adhesion because it is operated by a non-contact method using a linear motor as a propulsion system and reduce the overall construction costs by its compatibility with the conventional railway systems. Therefore, the design and characteristic analysis of a coreless-type superconducting Linear Synchronous Motor (LSM) for 600km/h very high speed railway system are conducted in this paper. The designed coreless-type superconducting LSMs are the distributed winding model, the concentrated 1 layer winding model and the concentrated 2 layer winding model, respectively. In addition, the characteristic comparison studies on each LSM are conducted.

• Journal of the Korea Concrete Institute
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• v.17 no.6 s.90
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• pp.1053-1064
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• 2005

The mechanical damage of concrete is normally attributed to the formation of microcracks and their propagation and coalescence into macroscopic cracks. This physical degradation is caused from progressive and hierarchical damage of the microstructure due to debonding and slip along bimaterial interfaces at the mesoscale. Their growth and coalescence leads to initiation of hairline discrete cracks at the mesoscale. Eventually, single or multiple major discrete cracks develop at the macroscale. In this paper, from this conceptual model of mechanical damage in concrete, the computational efforts were made in order to characterize physical cracks and how to quantify the damage of concrete materials within the laws of thermodynamics with the aid of interface element in traditional finite element methodology. One dimensional effective traction/jump constitutive interface law is introduced in order to accommodate the normal opening and tangential slips on the interfaces between different materials(adhesion) or similar materials(cohesion) in two and three dimensional problems. Mode I failure and mixed mode failure of various geometries and boundary conditions are discussed in the sense of crack propagation and their spent of fracture energy under monotonic displacement control.