• Title/Summary/Keyword: adapted therapy

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A Monte Carlo Simulation Study of a Therapeutic Proton Beam Delivery System Using the Geant4 Code (Geant4 몬테카를로 코드를 이용한 양성자 치료기 노즐의 전산모사)

  • Shin, Jungwook;Shim, Hyunha;Kwak, Jungwon;Kim, Dongwook;Park, Sungyong;Cho, Kwan Ho;Lee, Se Byeong
    • Progress in Medical Physics
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    • v.18 no.4
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    • pp.226-232
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    • 2007
  • We studied a Monte Carlo simulation of the proton beam delivery system at the National Cancer Center (NCC) using the Geant4 Monte Carlo toolkit and tested its feasibility as a dose verification framework. The Monte Carlo technique for dose calculation methodology has been recognized as the most accurate way for understanding the dose distribution in given materials. In order to take advantage of this methodology for application to external-beam radiotherapy, a precise modeling of the nozzle elements along with the beam delivery path and correct initial beam characteristics are mandatory. Among three different treatment modes, double/single-scattering, uniform scanning and pencil beam scanning, we have modeled and simulated the double-scattering mode for the nozzle elements, including all components and varying the time and space with the Geant4.8.2 Monte Carlo code. We have obtained simulation data that showed an excellent correlation to the measured dose distributions at a specific treatment depth. We successfully set up the Monte Carlo simulation platform for the NCC proton therapy facility. It can be adapted to the precise dosimetry for therapeutic proton beam use at the NCC. Additional Monte Carlo work for the full proton beam energy range can be performed.

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The Effect of Open and Closed Chain Exercise on Lower Extremity Muscle Activity in Adults (열린사슬운동과 닫힌사슬운동이 정상성인의 하지근활성도에 미치는 영향)

  • Kwon, Yoo-Jung;Park, Soo-Jin;Kim, Kyoung
    • Journal of the Korean Society of Physical Medicine
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    • v.7 no.2
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    • pp.173-182
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    • 2012
  • Purpose : This study was investigated the effect of lower extremity muscle activity during open kinetic chain exercise (OKC) and closed kinetic exercise (CKC) in normal young adults. Methods : The participants were consisted of forty-one. All subjects were randomly assigned to two groups of open kinetic chain exercise group (n=21) and closed kinetic chain exercise group(n=20). It was perform 3 sets, 3 times per week for 6 weeks both open kinetic chain exercise group and closed kinetic chain exercise group. Subjects were assessed for each subject took pre-test, post-test in 2 weeks, post-test in 4 weeks, post-test in 6 weeks measurement the surface EMG data for vastus medialis and lateralis, lateral and medial hamstring, lateral and medial gastrocnemius, tibialis anterior. Results : The vastus medialis and lateralis muscle activity was significantly increased within the intervention period both group(p<.05). The lateral and medial part of hamstring muscle activity was significantly increased with in the intervention period(p<.05). The tibialis anterior muscle activity of open kinetic chain exercise group and closed kinetic chain exercise group was significantly increased in the intervention period(p<.05). The lateral and medial part of gastrocnemius muscle activity of open kinetic chain exercise group and closed kinetic chain exercise group was significantly increased with in the intervention period(p<.05). Conclusion : It was found that both open kinetic chain exercise and closed kinetic chain exercise was significantly increased muscle activity. Further studies are needed to analyzed long term effects and subjects resulting from these changed. these exercises can be selectively adapted not only as treatment exercise for patients but also as preventive exercise for normal person to improve balancing ability by conducting proper amount of exercise for each individual's condition and stage.

Exploring Concurrent Validity and Item Level Analysis for Two Korean Versions of Health-Related Quality of Life Instrument: EQ-5D vs. WHOQOL-BREF

  • Choi, Bongsam
    • Physical Therapy Korea
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    • v.27 no.4
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    • pp.233-240
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    • 2020
  • Background: Cross-culturally adapted questionnaires may not be comparable to their original version. Objects: To examine concurrent validity of two health-related quality of life (HRQOL) instruments for the Korean versions of EuroQOL-5 Dimension (EQ-5D) and the abbreviated version of the World Health Organization Quality of Life (WHOQOL-BREF) instrument. Methods: A total of 139 cancer survivors from two rehabilitation institutes was recruited. All participants were registered for palliative rehabilitation care. Both instruments were concurrently administered by health care providers following the second bout of the rehabilitation cares. Rasch partial credit model and Spearman's correlation analysis were used to investigate: 1) dimensionality, 2) hierarchical item difficulty, and 3) concurrent validity using correlations between two instruments. Results: For the WHOQOL-BREF, all items except negative feeling, pain, dependence of medical aid, were found to be acceptable, while all items of EQ-5D were acceptable. There was an evidence of negative correlations between EQ-5D and 4 domains of WHOQOL-BREF. Two correlations were strong (EQ-5D vs. physical health domain, ρ = -0.610, 95% CI = -0.716 to -0.475) and moderate (EQ-5D vs. psychosocial domain, ρ = -0.402, 95% CI = -0.546 to -0.236). Other two correlations were weak (EQ-5D vs. social relationship and environmental domains, ρ = -0.242, 95% CI = -0.401 to -0.075 and ρ = -0.364, 95% CI = -0.514 to -0.207, respectively). Item difficulty calibrations of the two measurements were ranged from -0.84 to 0.86 for the EQ-5D and -1.07 to 1.06 for the WHOQOL-BREF. Conclusion: The study provides some supports for the concurrent validity of the two Korean versions of HRQOL instrument, with evidences of weak to strong correlations between the EQ-5D and four domains of the WHOQOL-BREF applied to various cancer survivors. Additionally, the cancer survivors appeared to have more of a tendency to view the EQ-5D items as being slightly more challenging than the WHOQOL-BREF items.

A Case Study on Child-Centered Play Therapy for Young Child's Anger (분노하는 아동의 상담사례연구)

  • Kim, Tae-Sun
    • Industry Promotion Research
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    • v.7 no.3
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    • pp.65-70
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    • 2022
  • The purpose of this study was to investigate the child counselling process of a 5-year old girl with anger problem. Her mother had difficult on caring a child. The researcher conducted 47 session of child counseling through child-centered play therapy once per week during 14months for 40 minutes. Parent consultation session follwed for 10 minutes. The child expressed her aggression, control, desire of affection and power during the sessions. As a result, the child's anger decreased, and child-mother relationship improved. Finally, the child successfully adapted new school life. The mother reported that raising children was much easier than before. This study is meaningful that it is a case study of a child's intervention in counseling prior to her entering elementary school. This study showed her adaptive school lifestyle during the beginning of the first year.

A Case Study on Child-Centered Play Therapy for Inattention and Impulsivity Young Child (산만 및 충동성향의 아동상담 단일사례연구)

  • Kim, Tae-Sun
    • Industry Promotion Research
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    • v.7 no.3
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    • pp.71-75
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    • 2022
  • The purpose of this study was to investigate the child counselling process of a 6-year old girl. The child has showed inattention and impulsity. Her mother had difficulty on caring a child. The researcher conducted 63 session child counseling through play therapy once per week after tested clinical psychological full battery. During the counseling process, a child showed desire of affection and aggressive and impulsive behavior through the child's leading play. As a result the child's inattention and impulsivity decreased, and child-mother relationship improved. The child could express her feelings to their parents in concrete terms. Finally, the child successfully adapted new school life. The mother reported that raising children was much easier than before, and she decided to have a follow-up counseling once a month. This study is meaningful in that it is a case study conducted during 1 year and 8months since she was 6-year old. The young child becomes primary school girl. In this study, it was confirmed that children had an adaptive school life during the first and second grades.

Orthodontic-prosthodontic interdisciplinary treatment for a patient with multiple missing posterior teeth and unilateral scissors bite (다수의 구치 상실과 편측성 가위교합을 갖는 환자의 보철 교정 협진 치료)

  • An, Kiyong
    • The Journal of the Korean dental association
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    • v.53 no.11
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    • pp.844-854
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    • 2015
  • This clinical report describes an orthodontic-prosthodontic interdisciplinary treatment for a patient with multiple missing teeth and unilateral scissors bite. A 47-year-old female presented with multiple missing posterior teeth, anterior large overjet, deep bite, and posterior scissors bite on the right premolar area. Periodontal therapy was performed and followed by orthodontic treatment. The maxillary anterior teeth were initially aligned, then two implants were placed for the left mandibular molars to increase occlusal vertical dimension. The scissors bite between the right maxillary and mandibular premolars were corrected using the miniscrews as an anchorage. Other implants were placed for the right maxillary and mandibular molars after the occlusal planes and occlusal relationship were harmonized. The patient adapted well to altered vertical dimension without any specific problems including peri-implant marginal bone loss. Interdisciplinary approach resolve the complex orthodontic-prosthodontic problems and concluded in successful results.

Cross-cultural Adaptation and Psychometric Evaluation of the Korean Version of the A-ONE (한국판 일상생활활동중심 작업기반 신경행동평가(A-ONE)의 개발 및 평가)

  • Kang, Jaewon;Park, Hae Yean;Kim, Jung-Ran;Park, Ji-Hyuk
    • Therapeutic Science for Rehabilitation
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    • v.10 no.2
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    • pp.109-128
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    • 2021
  • Objective : The purpose of this study was to develop a Korean version of the Activities of Daily Living (ADL)-focused Occupation-Based Neurobehavioral Evaluation (A-ONE) through cross-cultural adaptation and examine its validity and reliability. Methods : This study translated the A-ONE into Korean and performed cross-cultural adaptation for the Korean population. After the development of the Korean version of the A-ONE, cross-cultural and concurrent validities were analyzed. Internal consistency, test-retest reliability, and inter-rater reliability were also evaluated. Results : We adapted three items to the Korean culture. The Korean version of the A-ONE showed high cross-cultural validity with a content validity index (I-CVI) >0.9. It correlated with the Functional Independence Measure (FIM) (r=0.52-0.77, p<0.001), except for communication. Cronbach's α was 0.58-0.93 for the functional independence scale (FI) and 0.42-0.93 for the neurobehavioral specific impairment subscale (NBSIS). Intraclass correlation coefficients (ICCs) indicated high test-retest and inter-rater reliability for FI (ICC=0.79-1.00 and 0.75-1.00, respectively) and NBSIS (ICC=0.74-1.00 and 0.72-1.00, respectively). Conclusion : The Korean version of the A-ONE is well adapted to the Korean culture and has good validity and reliability. It is recommended to evaluate ADL performance skills and neurobehavioral impairments simultaneously in Korea.

A Translation and Construct Validity Study of the Evaluation in Ayres Sensory Integration® (EASI) (Evaluation in Ayres Sensory Integration® (EASI)의 번역 및 구성타당도 연구)

  • Kim, Kyeong-Mi;Lee, Ji-Hyun;Jung, Hyerim;Choi, Jeong-Sil;Hong, Eunkyoung
    • The Journal of Korean Academy of Sensory Integration
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    • v.19 no.1
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    • pp.24-38
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    • 2021
  • Objective : This study aimed to create a Korea translation of the Evaluation in Ayres Sensory Integration (EASI) and to then test the adapted version for construct validity. Methods : The translation and content validation process were conducted in accordance with a four-step process, namely translation, integration, content validity examination, and backward translation. The construct validity of the translated version was evaluated using the EASI for children aged 3~12 years with and without sensory integration problems, comparing the two groups as well as preschool and school-aged groups. The group comparison was analyzed using the Mann-Whitney U test in SPSS. Results : In terms of content validity, all 20 items averaged more than 3.17 points. Of the four EASI categories, there was a difference in Sensory Perception (p=0.044) between the typical and sensory integration groups, and there was a statistical difference between tactile and vestibular sensations. Between the preschool and school-aged children, statistical difference was observed in two categories, namely Praxis and Ocular-Postural-Bilateral Motor Integration. Conclusion : Based on its construct validity, the Korean version of EASI is suitable for use in research. The construct validity study highlighted items that explain differences between typical and diagnostic children and items that explain those differences by age. Our findings could therefore be considered when interpreting EASI results.

Higher dextrose delivety via TPN related to the development of hyperglycemia in non-diabetic critically ill patients

  • Lee, Ho-Sun;Koh, Shin-Ok;Park, Moo-Suk
    • Nutrition Research and Practice
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    • v.5 no.5
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    • pp.450-454
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    • 2011
  • The beneficial effects of total parenteral nutrition (TPN) in improving the nutritional status of malnourished patients during hospital stays have been well established. However, recent randomized trials and meta-analyses have reported an increased rate of TPN-associated complications and mortality in critically ill patients. The increased risk of complications during TPN therapy has been linked to the development of hyperglycemia, especially during the first few days of TPN therapy. This retrospective study was conducted to determine whether the amount of dextrose from TPN in the 1st week in the intensive care unit (ICU) was related to the development of hyperglycemia and the clinical outcome. We included 88 non-diabetic critically ill patients who stayed in the medical ICU for more than two days. The subjects were 65 ${\pm}$ 16 years old, and the mean APACHE (Acute Physiology and Chronic Health Evaluation) II score upon admission was 20.9${\pm}$7.1. The subjects received 2.3${\pm}$1.4 g/kg/day of dextrose intravenously. We divided the subjects into two groups according to the mean blood glucose (BG) level during the 1st week of ICU stay: <140 mg/dl vs ${\geq}$ 140 mg/dl. Baseline BG and the amount of dextrose delivered via TPN were significantly higher in the hyperglycemia group than those in the normoglycemia group. Mortality was higher in the hyperglycemia group than in the normoglycemia group (42.4% vs 12.8%, P=0.008). The amount of dextrose from TPN was the only significant variable in the multiple linear regression analysis, which included age, APACHE II score, baseline blood glucose concentration and dextrose delivery via TPN as independent variables. We concluded that the amount of dextrose delivered via TPN might be associated with the development of hyperglycemia in critically ill patients without a history of diabetes mellitus. The amount of dextrose in TPN should be decided and adapted carefully to maintain blood glucose within the target range.

Effects of EA Application to GV20 and LI4 on BAX and NF-kB Expression of the SD-Rat's Hippocampus with Global Ischemia

  • Choi, Jung-Hyun;Kim, Sung-Won;Lee, Jae-Gap;Kim, Min-Hee;Kim, Ji-Sung;Choi, Yoo-Rim;Yun, Young-Dae;Kim, Chi-Hyok;Kim, Yong-Seong;Kim, Nyeon-Jun;Lee, Ju-Hwan;Lee, Sang-Bin
    • Journal of International Academy of Physical Therapy Research
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    • v.1 no.2
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    • pp.136-142
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    • 2010
  • This study aims to reveal how EA affects BAX and NF-kB involved in cell deaths from global ischemia, and to do this, observes the changes of BAX and NF-kB caused by EA application after transient global ischemia. The experimental method is to give rise to global ischemia and apply EA to 27 SD rats with the particulars of being six-week-old, male, around-300 gram-weighing, and adapted to laboratory environment for more than a week, and divide them into three groups, that is, GV20 EA group(n=9), L14 EA group(n=9), no-treatment GI group(n=9), and then observe their changes of BAX and NF-kB at the time lapse of 6 hours, 9 hours and 12 hours after ischemia, using western blotting. The numerical decrease of BAX expression at the time lapse of 9 hours after EA application, though not statistically significant, was observed in GV20 EA group and L14 EA group, and the NF-kB expression appeared statistically significant decrease in GV20 EA group and L14 EA group, but the expression was higher in the group with EA application. Therefore, EA application at the early phase of global ischemia is considered to affect BAX and NF-kB and play a positive role in decreasing apoptosis and cell deaths by inflammation.

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