• BMB Reports
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• v.45 no.3
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• pp.165-170
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• 2012

We report here that an ethanol extract of Tetracera scandens, a Vietnamese medicinal plant, has anti-HIV activity and possesses strong inhibitory activity against HIV-1 reverse transcriptase (RTase). Using a MT-4 cell-based assay, we found that the T. scandens extract inhibited effectively HIV virus replication with an $IC_{50}$ value in the range of 2.0-2.5 ${\mu}g$/ml while the cellular toxicity value (CC50) was more than 40-50 ${\mu}g$/ml concentration, thus yielding a minimum specificity index of 20-fold. Moreover, the anti-HIV efficacy of the T. scandens extract was determined to be due, in part, to its potent inhibitory activity against HIV-1 RTase activity in vitro. The inhibitory activity against the RTase was further confirmed by probing viral cDNA production, an intermediate of viral reverse transcription, in virus-infected cells using quantitative DNA-PCR analysis. Thus, these results suggest that T. scandens can be a useful source for the isolation and development of new anti-HIV-1 inhibitor(s).

• Korean Journal of Veterinary Research
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• v.53 no.4
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• pp.231-237
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• 2013

This study aimed to assess the attraction effect against Lycorma delicatula and antioxidant activity of hexane, chloroform, butanol and water fraction obtained from Ailanthus altissima methanol extract. The attraction effect of chloroform fraction showed the highest activity (47%) as compared to that of other fractions. In the DPPH radical scavenging activity, methanol and butanol fraction showed higher antioxidant activity than other solvent fractions. From the above results, the potential chloroform fraction was further performed by local irritation test in New Zealand white rabbits. In eye irritation test, chloroform fraction showed moderate irritant at high concentration 0.5 g/site/mL, but there was no eye irritation at low concentration (0.05 g/site/mL). In accordance with the Draize evaluation of skin irritation, the primary irritation index was calculated to 3.3 and 0.68 at high (0.5 g/site/mL) and low concentration (0.05 g/site/mL) causing moderate and mild irritation, respectively. On the basis of this study, Ailanthus altissima chloroform fraction could be safely considered to be a candidate of attractant against Lycorma delicatula.

• Journal of Microbiology and Biotechnology
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• v.26 no.5
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• pp.953-958
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• 2016

Chitosan-based film-forming gel is regarded as a promising vehicle for topical delivery of antimicrobial agents to skin wounds, since it protects from microbial infection and the cationic polymer itself possesses antibacterial activity. In this study, possible synergistic interaction against common skin pathogens between the cationic polymer and tyrothricin (TRC), a cyclic polypeptide antibiotic, was investigated, by determining the concentration to inhibit 90% of bacterial isolates (MIC). The addition of the polysaccharide to TRC dramatically reduced the MIC values of TRC by 1/33 and 1/4 against both methicillin-resistant and methicillin-susceptible Staphylococcus aureus, respectively. The synergism of TRC and chitosan combination against both strains was demonstrated by the checkerboard method, with a fractional inhibitory concentration index below 0.5. Moreover, co-treatment of TRC and chitosan exhibited antibacterial activity against Pseudomonas aeruginosa, due to the antibacterial activity of chitosan, whereas TRC itself did not inhibit the gram-negative bacterial growth. These findings suggested that the use of chitosan-based film for topical delivery of TRC could be an alternative to improve TRC antimicrobial activity against strains that are abundant in skin wounds.

• Journal of Korean Society of Rural Planning
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• v.23 no.2
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• pp.9-17
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• 2017

Rural development policy has changed from hardware based development to community revitalization. The purpose of this study is to analyze social network of collaborative activity among rural organizations as fundamental of community. The material used in this study is a record of collaborative activites in the community newsletter of Hong-Dong area. 161 of collaborative activities (links) and 75 of organizations (nodes) are investigated in network. 6 collaborative activity type ('Education', 'Socializing', 'Meeting', 'Culture', 'Event' and 'Labor') is classified. 'Socializing' is inclusive of approximately half of whole network (50.67%). Closeness centraization, degree centralization and betweenness centralization are measured on top in 'Education', 'Meeting' and 'Event' type. Scatter plot analysis using degree and betweenness centrality index, 'Maeul Revitalization Center', 'Balmak Library', 'Woori-Maeul Medical Co-op', 'Support Center for Female Farmers', 'Hongdong Middle School' and 'Mundang Sustainable Agriculture Education Center' are resulted as the core organization in network. Geographical distribution of collaborative activity is not only concentated in Hong-Dong Myeon but also networked with adjacent administrative district. This study finds its purpose in the detailed analysis of network characteristics of collaborative activity within Hong-Dong area which is representative developed rural community in Korea.

• Journal of the Korean Wood Science and Technology
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• v.44 no.4
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• pp.494-504
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• 2016

Eucalyptus oils are widely used as spices, perfume industrial materials, food flavorings, and medicines. Several types of Eucalyptus oils also have insecticidal activity and as carminative. This study investigated the chemical composition, insecticidal (larvicidal and repellent) activity of E. urophylla oil against filarial mosquito Culex quinquefasciatus. E. urophylla oil was obtained from fresh leaves by water-steam distillation with oil yield 1.08%. E. urophylla oil in this study had no color (clear), has odor (typical eucalyptus), with specific gravity 0.941; refractive index 1.465; miscibility in 70% ethanol 1 : 3; and optical rotation (-) $5.83^{\circ}$. The major compounds of the oil were ${\alpha}$-pinene (11.73%), 1,8-cineole (49.86%), ${\beta}$-ocimene (6.25%), ${\gamma}$-terpinene (9.11%), and ${\alpha}$-terpinyl acetate (7.63%). The result showed the excellent insecticide activity against C. quinquefasciatus. The oil provided larvicidal activity with $LC_{50}$: 80.21 ppm and $LC_{90}$: 210.18 ppm, and repellent activity with $IC_{50}$: 0.82% and $IC_{90}$: 4.88%. The present study showed the effectiveness of E. urophylla as natural insecticide against C. quinquefasciatus, the mosquito vector of filariasis.

• Journal of Acupuncture Research
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• v.18 no.2
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• pp.175-185
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• 2001

Objectives : In order to study the effect of taping therapy on the activity of daily living of poststroke-hemiplegic patients, a clinical study was performed. Methods : Twenty patients with poststroke-hemiplegia were randomized into two groups. Ten patients treated with kinesio taping. The other ten patients didn't treat with kinesio taping. Tapes were applied to the Deltoid, Supraspinatus, Infraspinatus, Brachioradialis, Gluteus Maximus, Adductor muscles of the hip, Sartorius and Tibialis Anterior. The activity of daily living was measured with a modifted barthel index(MBI). The taping therapy was performed twice a week for 2 weeks. Results : In terms of improvement of activity of daily living, the smaple group showed statistically meningful increase after 2 times treatment compared with control group(p<0.05). In terms of self care score of MBI, the sample group showed statistically meningful increase after 1 time treatment with the control group(p<0.05). In terms of mobility score of MBI, the sample group showed statistically meningful increase after 3 times treatment with the control group(p<0.05). Conclusions : These results support that taping therapy is significantly effective in improvement of the activity of daily living of poststroke-hemiplegic patients.

• Journal of the Korea Society of Computer and Information
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• v.23 no.10
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• pp.119-125
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• 2018

The purpose of this study was to investigate the effect of health care on the body composition and metabolic Syndrome risk factors in male office workers. The subjects of this study were 30~40's male office workers and their physical activities were increased by mobile healthcare. The date analysis in this study was carried out paired t­test using SPSS 20.0 version(${\alpha}=.05$). The result of study were as follow: First. body composition kg(p<.015), BMI(p<.041), WC(p<.026) were significantly decreased after Increase in Physical Activity Using Mobile Health Care, although these did not reach statistical significance, SMM(p<.123), BF(p<.059) was slightly increased and decreased trend. Second, SBP(p<.300), DBP(p<.384) was slightly decreased trend and BS(p<.034) were significantly decreased after Increase in Physical Activity Using Mobile Health Care, Third, plasma TC(p<.015), TG(p<.003), LDL-C)(p<.000) were significantly decreased after Increase in Physical Activity Using Mobile Health Care and plasma HDL-C (p<.003) were significantly increased. These results suggest that increased physical activity using mobile health care has a positive effect on the body composition and metabolic syndrome index in male office workers. Sedentary lifestyles could be changed by Continuous feedback using mobile healthcare.

• The Korean Journal of Financial Management
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• v.25 no.2
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• pp.165-190
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• 2008

The degree of informational asymmetry relating to the expiration of index derivatives is usually increased as an expiration day of index derivatives approaches. The increase in the degree of informational asymmetry may have some effects on trading behavior of investors. To examine what the effects look like, 'life cycle of index derivatives' in this study is defined as three adjacent periods around expiration day: pre-expiration period(a week before the expiration day), post-expiration period(a week after the expiration day), and remaining period. It is inspected whether stock investor's trading behavior is changed according to the life cycle of KOSPI200 derivatives and what the reason of the changing behavior is. We have four results. First, trading behavior of each investor group is categorized into three patterns: ㄱ-pattern, L-pattern and U-pattern. The level of trading activity is low for pre-expiration period and normal for other periods in the ㄱ-pattern. L-pattern means that the level of trading activity is high for post-expiration period and normal for other periods. In the U-pattern, the trading activity is reduced for remaining period compared to other periods. Second, individual investors have ㄱ-pattern of trading large stocks according to the life cycle of KOSPI200 index futures while they show U-pattern according to the life cycle of KOSPI200 index options. Their trading behavior is consistent with the prediction of Foster and Viswanathan(1990)'s model for strategic liquidity investors. Third, trading pattern of foreign investors in relation to life cycle of index derivatives is partially explained by the model, but trading pattern of institutional investors has nothing to do with the predictions of the model.

• Journal of Oriental Neuropsychiatry
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• v.18 no.1
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• pp.37-61
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• 2007

Objective : By examining EEG status in Korean Traditional Medicine (KTM) from the viewpoint of 'form-qi theory(形氣論)', We wish to prepare for the fundamentals of applicability of KTM diagnoses to EEG. In addition, through reinterpretation of existing Western Medicine reports from the viewpoint of KTM, We tried to find out interrelationship between them. Method : In this paper, a methodology applicable to KTM diagnoses of EEG is presented from the EEG features in waveform characteristics, personalized diversity, and cognitive activity reflection. Results : Frequency bands are assigned to corresponding one of the eight trigrams in terms of yin/yang balance, which is analogous with EEG spectrum analysis mostly used in EEG quantification. The amplitude ratio of each EEG for each frequency band gives meaningful index numbers which can be used in EEG data interpretation, and every index number is named after the sixty four hexagrams. These approaches are adopted through both '4-band classification system and '6-band classification system', and applied to pre-existing reported EEG data obtained from normal adults. These analyses show that changes and distribution pattern in the index numbers are observed as a whole on both left-right line and front-back line connecting EEG measurement cephalic electrodes. And differences in distribution pattern of three index numbers deduced from '6-band classification system' are discussed according to constitution. Conclusion : The index numbers introduced here, which are the spectral power ratio for each EEG, are based on KTM yin/yang balance. These index numbers vary according to cephalic location, so its application in terms of traditional meridian theory is strongly expected. The index number distribution also shows different patterns according to constitution.

• The Korean Journal of Applied Statistics
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• v.28 no.1
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• pp.103-114
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• 2015

The role of small and medium enterprises as an economic growth factor has been accentuated; consequently, the need to develop a business forecast model and indexes that accurately examine business situation of small and medium enterprises has increased. Most current business model and indexes concerning small and medium enterprises, released by public and private institutions, are based on Business Survey Index (BSI) and depend on subjective (business model and) indexes; therefore, the business model and indexes lack a capacity to grasp an accurate business situation of these enterprises. The business forecast model and indexes suggested in the study have been newly developed with Principal Component Analysis(PCA) and weight method to accurately measure a business situation based on reference dates addressed by the National Statistical Office(NSO). Empirical studies will be presented to prove that the newly proposed business model and indexes have their basis in statistical theory and their trend that resembles the existing Composite Index.