• Journal of the Korean Society of Physical Medicine
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• v.16 no.4
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• pp.13-21
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• 2021

PURPOSE: This study examined the effects of action observational training with acoustic stimulation (AOTA) on the balance and gait ability in stroke patients. METHODS: Forty-five chronic stroke patients were divided into three groups. The AOTA group (n = 15) received training via a video that showed a normal gait with the sound of footsteps. The action observation training (AOT) group (n = 15) received AOT without acoustic stimulation. The control group (n = 15) received physical training. Each intervention was applied once per day, three times per week for six weeks. The participants in the AOTA and AOT groups had five minutes of AOT. The participants in the all group had 20 minutes of physical training. All participants were measured using the Berg Balance Scale, the Timed Up and Go Test, the Functional Reaching Test, 10 Meter Walk Test, six Minute Walk Test, and Dynamic Gait Index. The collected data were analyzed using SPSS version 20.0 for Windows. The between- and within-group comparisons were analyzed using the one-way analysis of variance (ANOVA) test and a paired t-test, respectively. For all statistical analyses, the significance level was set to .05. RESULTS: The one-way ANOVA test identified significant differences among the measurement results of the three groups (p < .05). Post hoc analyses indicated the AOTA group to undergo more significant balance and gait changes than the control group (p < .05). CONCLUSION: The gait and balance abilities could be improved effectively for patients with stroke when action observation training and acoustic stimulation were applied simultaneously.

• The Journal of Korean Physical Therapy
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• v.31 no.3
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• pp.157-160
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• 2019

Purpose: We compared the activation pattern of the mirror neurons (MN) between two types of hand movement according to action observation using functional MRI. Methods: Twelve right-handed healthy subjects (5 male and 7 female, mean age $21.92{\pm}2.02years$) participated in the experiment. During fMRI scanning, subjects underwent two different stimuli on the screen: 1) video clips showing repeated grasping and releasing of the ball via simple hand movement (SHM), and (2) video clips showing an actor performing a Purdue Pegboard test via complex hand movement (CHM). paired t-test in statistical parametric mapping (SPM) was used to compare the activation differences between the two types of hand movement. Results: CHM as compared with the SHM produced a higher blood oxygen level dependent (BOLD) signal response in the right superior frontal gyrus, left inferior and superior parietal lobules, and lingual gyrus. However, no greater BOLD signal response was found by SHM compared with CHM (FWE corrected, p<0.05). Conclusion: Our findings provided that the activation patterns for observation of SHM and CHM are different. CHM also elicited boarder or stronger activations in the brain, including inferior parietal lobule called the MN region.

• Korean Institute of Interior Design Journal
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• v.19 no.2
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• pp.176-185
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• 2010

Due to Korean government's reduction policy of the level of local administration, the government tries to become smaller and more efficient organization and in accordance with this movement, they try to transfer the human power and work of the office of Eup, Myeon, Dong to the office of Si, Goon, Goo so that they can take administrative action quickly, increase the efficiency of administration by preventing the overlapping of administrative task, improve the administrative service toward the citizens and make a functional shift of Inhabitant Self-Government Center in a way that is aimed at improving the quality of life of the inhabitants by setting up cultural, welfare facilities and forming the local community. Hereupon I expect this study will help to show the ways of composing the space of community center, accommodating the various demands of inhabitants through appropriate area calculation of functional area, increasing the efficiency of government officers' administrative support and also will be the guide for the architectural designs of the community centers. For this purpose, I have investigated community centers of 8 Dongs out of 11 Dongs in Goon-po Si that was chosen to be operating the pilot program of the office of Eup, Myeon, Dong's functional shift and obtained excellent results. I have surveyed how the functional spaces are being used, interviewed the government officials, examined the size of the functional and required space with Building card of a plan and the analyzed results are as follows.

• Asian-Australasian Journal of Animal Sciences
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• v.16 no.4
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• pp.596-608
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• 2003

Weaning is a complex phase when the mammal suffers the action of different stressors that contribute to negatively affect the efficiency of the intestinal mucosa and of the whole local integrated system, that acts as barrier against any nocuous agent. The components of this barrier are mechanical, chemical, and bacteriological; immunological and not. The development of contact with a saprophyte microflora and the maintenance of feed intake after the interruption of motherly nutrition are essential for the maturation of an equilibrated local immune function and for a functional integrity of villi. Opportunities and limits of some dietary strategies that can contribute to reduce negative effects of weaning on health and performance are discussed. Knowledges on the possible mechanism of action of probiotics are upgraded, particularly for their supposed role in the balance between different immune functions (effectory/regulatory). Some tools to control pathogen microflora are reviewed (acids, herbs, immunoglobulin sources) and practical feeding systems are proposed.

• KSBB Journal
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• v.29 no.3
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• pp.199-204
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• 2014

To investigate the effect of Plantago asiatica L. Root extract on skin care, we measured anti-oxidant activity and whitening action. As a result of measuring DPPH radical scavenging activity to examine independent anti-oxidation of PRE, there was slight scavenging activity. Fluorescent materials DHE, DCF-DA and DHR were each used to measure superoxide anion, hydrogen peroxide, and hydroperoxide created in RAW 264.7 cells, all concentrations were found to dependently prevent ROS production. Tyrosinase activation was found to be blocked dose-dependant. Melanin production was also prevented dose-dependant, but the effects were slight. Therefore, it is expected to be used effectively in development of functional cosmetic materials.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.15 no.26
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• pp.125-136
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• 1992

Primary prevention of low back injury in industry has focused on assessing the person's ability to perform physical labor. If the job to be performed is known to require lifting and moving of materials which could stress the low back, then special consideration is given to the health and functional capability of the person, s back. The major pursuit in lifting task of research is to provide objective criteria based upon all of the relevant mechanical parameters which describe both man art task so as to minimize the probabilities of injury within the economic constraints of each organization. The purpose of this study is to predict the back compression of persons asked to lift objects while assuming different position by computer simulation. The primary result of this study is that the incidence of low back injury is correlated with higher lifting strenth requirements as determined by assessment of both the location and magnitude of the load lifted. It is, therefore, recommended that load lifting be considered potentially hazardous, and the action limit and the maximum permissiable limit be used to guide corrective action.

• Journal of Electrochemical Science and Technology
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• v.6 no.1
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• pp.7-15
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• 2015

3-(4-Iodophenyl)-2-imino-2,3-dihydrobenzo[d]oxazol-5-yl 4-methylbenzenesulfonate (4-IPhOXTs) was synthesized and its inhibiting action on the corrosion of stainless steel 316L (SS) in sulfuric acid was investigated by means of potentiodynamic polarization and electrochemical impedance spectroscopy (EIS). The results of the investigation show that this compound has excellent inhibiting properties for SS corrosion in sulfuric acid. Inhibition efficiency increases with increase in the concentration of the inhibitor. The adsorption of 4-IPhOXTs onto the SS surface followed the Langmuir adsorption model with the free energy of adsorption ΔG⁰_ads of −8.45 kJ mol⁻¹ . Quantum chemical calculations were employed to give further insight into the mechanism of inhibition action of 4-IPhOXTs.

• Molecules and Cells
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• v.38 no.4
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• pp.297-303
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• 2015

Skeletal muscle insulin resistance, which increases the risk for developing various metabolic diseases, including type 2 diabetes, is a common metabolic disorder in obesity and aging. If potential treatments are to be developed to treat insulin resistance, then it is important to fully understand insulin signaling and glucose metabolism. While recent large-scale "omics" studies have revealed the acetylome to be comparable in size to the phosphorylome, the acetylation of insulin signaling proteins and its functional relevance to insulin-stimulated glucose transport and glucose metabolism is not fully understood. In this Mini Review we discuss the acetylation status of proteins involved in the insulin signaling pathway and review their potential effect on, and relevance to, insulin action in skeletal muscle.

• BMB Reports
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• v.52 no.4
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• pp.227-238
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• 2019

GROWTH-REGULATING FACTORs (GRFs) are sequence-specific DNA-binding transcription factors that regulate various aspects of plant growth and development. GRF proteins interact with a transcription cofactor, GRF-INTERACTING FACTOR (GIF), to form a functional transcriptional complex. For its activities, the GRF-GIF duo requires the SWITCH2/SUCROSE NONFERMENTING2 chromatin remodeling complex. One of the most conspicuous roles of the duo is conferring the meristematic potential on the proliferative and formative cells during organogenesis. GRF expression is post-transcriptionally down-regulated by microRNA396 (miR396), thus constructing the GRF-GIF-miR396 module and fine-tuning the duo's action. Since the last comprehensive review articles were published over three years ago, many studies have added further insight into its action and elucidated new biological roles. The current review highlights recent advances in our understanding of how the GRF-GIF-miR396 module regulates plant growth and development. In addition, I revise the previous view on the evolutionary origin of the GRF gene family.

• Therapeutic Science for Rehabilitation
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• v.6 no.2
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• pp.37-45
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• 2017

Background: The presence of visuospatial impairment can make patients slow functional recovery and impede the rehabilitation process in TBI patients. Objective: The aim of this study is to investigate effects of prism adaptation treatment for functional outcomes in patients following traumatic brain injury. Methods: The subject received prism adaptation treatment for 2 weeks additionally during traditional rehabilitation for 4 weeks. The Patient has prism adaptation treatment while wearing wedge prisms that shift the external environment about $12^{\circ}$ leftward. The patient received 10 sessions, 15-20min each session. Outcome measures were visuospatial deficit(line bisection, latter cancellation), Visual and spatial perception(LOTCA-visual perception and spatial perception), motor function of upper extremity(FMA U/E; Fugl-Meyer motor assessment upper extremity, ARAT; Action research arm test), balance(BBS; Berg Balance Scale), mobility(FAC; Functional ambulation classification) and functional level(FIM; Functional independent measure). All Assessments took place on study entry and post-treatment assessments were performed at discharge from the hospital. Results: After prism adaptation, the visuospatial impairment scores improved as indicated in the line bisection(-15.2 to -6.02), latter cancellation(2 to 0) and LOTCA- spatial perception scores(7 to 9). The upper motor function improved as indicated in the scores of affected FMA U/E(21 to 40) and ARAT(4 to 22). Ambulation and balance improved as indicated in the BBS scores(25 to 38) and FAC scores(0 to 4). ADL function improved as indicated in the FIM total scores 54 to 70(motor 34 to 61, cognition 20 to 29). Conclusion: Prism adaptation did improve functional level such as motor functions and ADL abilities in TBI patient. Further research is recommended.