• Asia Pacific Journal of Business Review
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• 제1권2호
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• pp.17-35
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• 2017

This research is a case study that focuses on how conglomerate illegality and corresponding penalty affects corporate performance and strategy. The research aims to provide base information for policy-makers as well as the general public about the corporate environment. The analysis results can be summarized as follows. First, profitability is represented as an M-curve. Profitability falls from indictment to the final pronouncement of the corporate head and increases upon his or her return. The result suggests that the absence of a corporate head could result in low profitability as the firm is exposed to owner risk. Secondly, significant effects on investment were not found. Investment showed a continuous increase from indictment to final judgment. This could have resulted from investment decisions made prior to the indictment, which are generally long-term. Meanwhile, the rate at which investments rose for core subsidiaries were lower, which makes it reasonable to suspect dwindling executive capacity due to the absence of a corporate head. Thirdly, employment showed a slight increase, but the rate was found to be greater during the periods following the final judgment. From a political perspective, this increase can be inferred from a give-and-take tradeoff between corporate employment and the pardon of the corporate head.

• BMB Reports
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• 제50권7호
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• pp.373-378
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• 2017

The Jun activation-domain binding protein 1 (Jab1) induces p53 nuclear export and cytoplasmic degradation, but the underlying mechanism is poorly understood. Here, we show that phosphorylation at the threonine 155 residue is essential for Jab1-mediated p53 nuclear export. Jab1 stimulated phosphorylation of p53 at T155 was inhibited by curcumin, an inhibitor of COP9 signalosome (CSN)-associated kinases. The T155E mutant, which mimics phosphorylated p53, exhibited spontaneous cytoplasmic localization in the absence of Jab1. This process was prevented by leptinomycin B (LMB), but not by curcumin. The substitution of threonine 155 for valine (T155V) abrogated Jab1-mediated p53 nuclear export, indicating that phosphorylation at this site is essential for Jab1-mediated regulation of p53. Although T155E can be localized in the cytoplasm in the absence of Mdm2, the translocation of T155E was significantly enhanced by ectopic Hdm2 expression. Our data suggests that Jab1-mediated phosphorylation of p53 at Thr155 residue mediates nuclear export of p53.

• Journal of Plant Biology
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• 제37권1호
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• pp.101-109
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• 1994

Chlamydomonas reinhardtii 배우체 유도기 동안에 polyamine 생합성 억제제인 MGBG[methylglyoxal bis-(guanylhydrazone); SAMDC 억제제] 1mM 처리구와 정상 대조구에서의 polyamine 함량 변화와 Chlamydomonas의 ct-DNA methylation과의 상호 연관성을 조사한 결과, 전반적으로 137C(＋)와 137C(-)의 정상 대조구에서 polyamine 수준은 배우체 유도기 전반에 걸쳐서 감소추세로 나타났으나, 특히 137C(＋)가 137C(-)보다 polyamine 함량이 많았으며 동시에 감소량도 컸다. 1mM MGBG 처리구에서는 137C(＋)의 spermidine 함량이 정상 대조구보다 증가하였다. In vitro에서 ctDNA methylation에 대한 MGBG의 영향은 정상 대조구에서보다도 1mM MGBG 처리구에서 약 20-30%의 ctDNA methylation 감소를 나타내었다. 또한, MGBG는 in vitro에서 DNA methylase에 대하여 억제효과를 나타내어TEk.

• Corrosion Science and Technology
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• 제3권5호
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• pp.187-193
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• 2004

We have investigated the differences between the general corrosion and microbiologically influenced corrosion (MIC) of steels in terms of electrochemical behavior and surface phenomena. Corrosion potential of steels in the absence of SRB (sulfate-reducing bacteria) shifted to a low level and was maintained throughout the experimental period (40 days). The potential in the presence of SRB, however, shifted to a noble level after 20 days' incubation, indicating the growth of SRB biofilms on the test metal specimens and a formation of corrosion products. In addition, the color of medium inoculated with SRB changed from gray to black. The color change appeared to be caused by the formation of pyrites (FeS) as a corrosion product while no significant color change was observed in the medium without SRB inoculation. Moreover, corrosion rates of various steels tested for MIC were higher than those in the absence of SRB. This is probably because SRB were associated with the increasing corrosion rates through increasing cathodic reactions which caused reduction of sulfate to sulfide as well as formation of an oxygen concentration cell. The pitting corrosions were also observed in the SRB-inoculated medium.

• 한국환경과학회지
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• 제12권11호
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• pp.1189-1196
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• 2003

The effect of boron and aluminum on the development of adventitious roots was studied in sunflower cuttings. Three-day-old seedlings were de-rooted and grown in nutrient solutions with or without boron and supplemented with different concentrations (from 50 to 700 ${\mu}$M) of aluminum. The number and length of the adventitious roots and proline content in adventitious roots in response to insufficient boron and aluminum stress were determined periodically. The micronutrient boron caused the development of numerous roots in the lower parts of the hypocotyl. A dose-response of boron-induced rooting yielded an optimum concentration of 0.1 mM boron. In the absence of boron, in the majority of the adventitious roots, a significant inhibition was observed with or without aluminum, indicating that the most apparent symptom of boron deficiency is the cessation of root growth. Increasing concentrations of aluminum caused progressive inhibition of growth and rooting of the hypocotyls, and a parallel increase in proline levels of adventitious roots. Supplemental boron ameliorated the inhibitory effect of aluminum, suggesting that aluminum could inhibit root growth by inducing boron deficiency. Ascorbate added to medium in the absence of boron improved root growth and induced a significant decrease in proline levels. These findings suggest that adventitious root growth inhibition resulting from either boron deficiency or aluminum toxicity may be a result of impaired ascorbate metabolism.

• Preventive Nutrition and Food Science
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• 제17권2호
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• pp.158-165
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• 2012

This study was designed to investigate whether the fatty acid composition could make a significant contribution to the oxidation stability of vegetable oils marketed in Korea. Ten kinds, 97 items of vegetable oils that were produced in either an industrialized or a traditional way were collected and analyzed for their fatty acid compositions and lipid oxidation products, in the absence or presence of oxidative stress. Peroxidability index (PI) calculations based on the fatty acid composition ranged from 7.10 to 111.87 with the lowest value found in olive oils and the highest in perilla oils. In the absence of induced oxidative stress, malondialdehyde (MDA), the secondary lipid oxidation product, was generated more in the oils with higher PI (r=0.890), while the tendency was not observed when the oils were subjected to an oxidation-accelerating system. In the presence of the oxidative stress, the perilla oils produced in an industrialized manner generated appreciably higher amounts of MDA than those produced in a traditional way, although both types of oils presented similar PIs. The results implicate that the fatty acid compositions could be a predictor for the oxidation stability of the vegetable oils at the early stage of oil oxidation, but not for those at a later stage of oxidation.

• Animal Systematics, Evolution and Diversity
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• 제14권2호
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• pp.91-98
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• 1998

필리핀 만다나오의 산호 모래틈에서 채집된 Anisonyches속 (Echiniscoididae과)에 속하는 해양완보류 2종, A. deliquus n. sp.와 A. diakidius Pollock을 보고한다. A. deliquus n. sp.는 Anisonyches속에 기록된 2종 중에서 발톱의 모양과 배열, 그리고 곤봉형 두부감각돌기와 제 4다리 위의 감각돌기가 없다는 점에서 A. mauritianus와 유사하나 제 1-3다리에 감각강모를 가지지 않은 점에서 뚜렷하게 구별된다. 저자들은 신종의 기재와 함께 Anisonyches속의 가장 중요한 형질은 발톱의 모양과 배열에 대하여 고찰하였다.

• 한국임상수의학회지
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• 제32권4호
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• pp.330-333
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• 2015

1년령 intact male mixed dog(체중 20 kg)가 복부 팽창과 심각한 운동불내성을 주증으로 내원하였다. 심전도 검사에서 심방정지와 함께 두드러진 서맥(46-79회/분)이 관찰되었다. 실험실 검사상 특별한 이상 소견은 관찰되지 않았다. 혈청 cortisol과 T4농도는 정상 범위였다. 영상검사상 심장비대, 복수, 모든 심장 chamber의 확장, 심방정지, transmitral A-peak 소실, 이첨판과 삼첨판 역류, 정상 좌심실 수축기 직경이 관찰되었다. 검사결과에 근거하여 특발성 심방정지로 진단되었으며 심부전에 준한 일반적인 치료를 실시하였다.

• 대한수의학회지
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• 제23권1호
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• pp.9-16
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• 1983

The effects of ethanol on Na-K-ATPase activity were investigated with cat kidney homogenate. The results were summarized as follows: 1. Na-K-ATPase activity was inhibited with dose-dependent manner by ethanol of higher concentration than 1%, and showed an estimated $I_{50}$ (the inhibitor concentration to cause 50% inhibition) of 7.5%. 2. Hydrolysis of ATP was linear with the incubation time in the absence and presence of 8% ethanol, whereas it was different with preincubation time in the presence of 15% ethanol. 3. Inhibition of Na-K-ATPase activity by ethanol was not affected by increased enzyme concentration, and showed the reversibility of the inhibitory pattern. 4. Kinetic studies of cationic-substrate activation of Na-K-ATPase showed that ethanol had both properties of classical competitive inhibition for $Mg^{{+}{+}}$ or $K^+ and non-competitive inhibition for ATP or $Na^+$. 5. Arrhenius plot yield two break point at $21^{\circ}$ and $30^{\circ}C$ in the absence of ethanol, whereas showing only one break point at $18^{\circ}C$ in the presence of 8% ethanol. These results suggested that ethanol inhibited Na-K-ATPase activity reversible through a disturbance of microenvironment of lipids associated with the enzyme.

• Journal of Korean Neurosurgical Society
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• 제29권4호
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• pp.550-554
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• 2000

Most extracranial schwannomas are solitary, but neurofibromas are frequently associated with other manietations of neurofibromatosis. Schwannomas that occur within the context of neurofibromatosis tend to be multiple, but multiple schwannomas without manifestation of neurofibromatosis type 2 are very rare. The authors report a very rare case of multiple spinal intradural schwannomas in the absence of neurofibromatosis Type 2 maniestations. A 40-year-old man suffered from longstanding low back pain and left side sciatica which was treated with two stage operations. MRI showed multiple intradural mass lesions extending from L1 vertebral segment to S1 vertebral segment. There were no clinical and radiological manifestations of Type 2 neurofibromatosis. Histologically confirmed diagnosis was schwannoma.