• Title/Summary/Keyword: abnormality

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Case of Anterior Segment Ischemia after Two Vertical Rectus Muscles Surgery (두 개의 수직근수술 후 발생한 전안부허혈 1예)

  • Ahn, Jayoung;Kim, Gyu Nam;Kim, Seong Jae;Chung, In Young;Seo, Seong Wook;Yoo, Ji Myong
    • Journal of The Korean Ophthalmological Society
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    • v.59 no.12
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    • pp.1195-1200
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    • 2018
  • Purpose: To report a case of anterior segment ischemia after superior and inferior rectus muscle surgery in a patient with superior rectus muscle enlargement. This is the first report in the Republic of Korea of anterior segment ischemia after two rectus muscles surgery. Case summary: An 80-year-old male was referred to our clinic with a 3 years history of diplopia. The patient had 30 prism diopters right eye hypertropia in the primary position and downgaze limitation. The orbital computed tomography scan revealed enlargement of the right superior rectus muscle. He underwent right superior rectus recession and inferior rectus resection. On postoperative day 2, slit lamp examination revealed diffuse corneal edema, Descemet's membrane folding, an aqueous flare and a dilated pupil. Treatment with 45 mg oral steroid was initiated, and 1% prednisolone acetate and 0.5% Levofloxacin eye drops were administered. At postoperative 1 month, the patient was orthophoric in the primary position, and there was no corneal edema, pupil abnormality or aqueous flare. Conclusions: Base on the present case, the possibility of anterior segment ischemia should be considered after even two muscles surgery, and older patients with vertical muscle surgery should be considered more carefully.

UV Effect on the Number of Primordial Germ Cells in the Embryo of Rana dybowskii (자외선이 산개구리 (Rana dybowskii) embryo의 시원생식세포 수에 미치는 영향)

  • 정해문;김원숙
    • The Korean Journal of Zoology
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    • v.27 no.1
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    • pp.13-24
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    • 1984
  • The fertilized eggs of Rana dybowskii were irradiated with UV (254 nm wave length) on the vegetal hemisphere to investigate the effects on the primordial germ cells (PGCs) and axis formation. The investigations were carried out in two ways; namely time course and UV dose. Up to 1,600 $ergs/mm^2$ of UV dose, irradiated at 60 min. after fertilization, there was no effect on the PGC number. However, the number of PGC comparing with that of unirradiated control was decreased more than 40%. As the amount of irradiation was increased, the number of PGC was inversely declined. The maximal dose of irradiation which eliminates PGC completely without inducing any axis abnormality was 4,800 $ergs/mm^2$. If the eggs were irradiated earlier with this amount the severer effect could be obtained. Thus the UV effect on the PGC number was most effective when irradiated by 60 min. post fertilization. Thereasfter stage. At UV doses over 9,600 $erge/mm^2$ other effects start to appear; namely abnormalities of nerual tube and axis formation. Therefore, comparative study on the UV sensitivity of PGC and axis formation was carried out. It was revealed that UV effect on the axis was drastically decreased at the time of $0.7\\sim0.8$ between fertilization and 1st cleavage, while the germ plasm was sensitive to UV until 4 cell stage.

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Crop Monitoring Technique Using Spectral Reflectance Sensor Data and Standard Growth Information (지상 고정형 작물 원격탐사 센서 자료와 표준 생육정보를 융합한 작물 모니터링 기법)

  • Kim, Hyunki;Moon, Hyun-Dong;Ryu, Jae-Hyun;Kwon, Dong-Won;Baek, Jae-Kyeong;Seo, Myung-Chul;Cho, Jaeil
    • Korean Journal of Remote Sensing
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    • v.37 no.5_1
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    • pp.1199-1206
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    • 2021
  • Accordingly, attention is also being paid to the agricultural use of remote sensing technique that non-destructively and continuously detects the growth and physiological status of crops. However, when remote sensing techniques are used for crop monitoring, it is possible to continuously monitor the abnormality of crops in real time. For this, standard growth information of crops is required and relative growth considering the cultivation environment must be identified. With the relationship between GDD (Growing Degree Days), which is the cumulative temperature related to crop growth obtained from ideal cultivation management, and the vegetation index as standard growth information, compared with the vegetation index observed with the spectralreflectance sensor(SRSNDVI & SRSPRI) in each rice paddy treated with standard cultivation management and non-fertilized, it was quantitatively identified as a time series. In the future, it is necessary to accumulate a database targeting various climatic conditions and varieties in the standard cultivation management area to establish a more reliable standard growth information.

A Study on the Method of Differentiating Between Elderly Walking and Non-Senior Walking Using Machine Learning Models (기계학습 모델을 이용한 노인보행과 비노인보행의 구별 방법에 관한 연구)

  • Kim, Ga Young;Jeong, Su Hwan;Eom, Soo Hyeon;Jang, Seong Won;Lee, So Yeon;Choi, Sangil
    • KIPS Transactions on Computer and Communication Systems
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    • v.10 no.9
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    • pp.251-260
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    • 2021
  • Gait analysis is one of the research fields for obtaining various information related to gait by analyzing human ambulation. It has been studied for a long time not only in the medical field but also in various academic areas such as mechanical engineering, electronic engineering, and computer engineering. Efforts have been made to determine whether there is a problem with gait through gait analysis. In this paper, as a pre-step to find out gait abnormalities, it is investigated whether it is possible to differentiate whether experiment participants wear elderly simulation suit or not by applying gait data to machine learning models for the same person. For a total of 45 participants, each gait data was collected before and after wearing the simulation suit, and a total of six machine learning models were used to learn the collected data. As a result of using an artificial neural network model to distinguish whether or not the participants wear the suit, it showed 99% accuracy. What this study suggests is that we explored the possibility of judging the presence or absence of abnormality in gait by using machine learning.

A Study on the Safety Code Development of Gas Engine Micro Combined Heat and Power System (소형 가스엔진 열병합 발전시스템 안전기준 개발)

  • Kwon, Jun-Yeop;Kim, Min-Woo;Lee, Jung-Woon
    • Journal of the Korean Institute of Gas
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    • v.25 no.4
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    • pp.27-35
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    • 2021
  • Recently, as a solution to the sharp drop in "power reserve ratio", it is being converted to a microgrid that enables bi-directional transmission and distribution. A microgrid is composed of a small-scale distributed power supply and a load. As a representative technology of distributed power generation, there is a Micro Combined Heat and Power system applied to homes and buildings. In this study, a safety standard was developed by dividing the power generation system, cooling system, lubrication system, and exhaust system to derive safety standards for a small gas engine power generation system with a gas consumption less than 232.6kW (200,000 kcal/h). In the case of the power generation system, a filter was installed and the system was stopped by detecting gas leakage and abnormalities in engine speed or output and the cooling system is stipulated to stop the system in case of insufficient cooling water or overheating. The lubrication system monitors the pressure and temperature of the lubricating oil and stops the system when an abnormality occurs, and the exhaust gas emission concentration regulation value was specified in accordance with domestic and foreign standards. Through the results of this study, it is judged that the safety of the gas engine power generation system can be improved and it can contribute to the commercialization of products.

The Effect of recovery method after forest walking exercise by intensity on heart rate, blood lactic acid and blood glucose (강도에 따른 산림 걷기 운동 시 회복방법이 심박수, 혈중젖산농도, 혈중글루코스에 미치는 영향)

  • Kim, Ki-Hong;Min, Jun-Won;Yu, Jeong-Bin;Kim, Jo-Eun;Son, Jae-Heon
    • Journal of the Korea Convergence Society
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    • v.12 no.12
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    • pp.401-409
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    • 2021
  • This study was conducted to investigate the effects of static recovery and dynamic recovery methods on heart rate, blood lactic acid concentration, and blood glucose during recovery after walking at the speed of 80bpm and 130+30bpm upon trekking of forest slopes in Taejo Mountain in Cheonan. 9 men in their 20s and 30s who had no abnormality in walking was subject to this experience. The result of through static recovery and dynamic recovery methods while trekking at the speed of 80bpm and 130+30bpm were analyzed by two-way repeated ANOVA. When there was a significant difference, the repeated method of contrast was applied to compare and analyze. The heart rate at 80bpm condition was significantly different depending on the method(p=.008) and time(p=.000) and there was no significant difference in blood lactic acid concentration for the recovery method(p=.401), but there was a significant difference depending on the time(p=.000). Blood glucose did not show significant difference according to the recovery method(p=.093), and there was significant difference depending on the time of static recovery method(p=.002). The heart rate in 130bpm + 30bpm condition was significantly different depending on to the method(p=.002) and time(p=.000), blood lactic acid concentration was significantly different depending on the method(p=.001) and time(p=.000), and blood glucose concentration was not significantly different between the time(p=090) and the method(p=.721).

Effect of Chronic Toxicity by Waste Microplastics (PET) on Daphnia magna (폐 미세플라스틱(PET)의 물벼룩 만성독성 연구)

  • Han, Bomi;Park, GeonU;Yoo, Seungwoo;Kim, Changhae;Jung, Jinho;Na, Joorim
    • Ecology and Resilient Infrastructure
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    • v.8 no.4
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    • pp.281-289
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    • 2021
  • Commercially used disposable cups undergo fragmentation in the environment and become microplastics (MPs). These MPs can be ingested by aquatic organisms and cause a range of adverse effects. We assessed the acute and chronic toxicity of disposable cup-derived MP fragments in Daphnia magna. MP fragments were identified as a polyethylene terephthalate (PET) fragment with a size of 33.18 ± 7.76 ㎛. The presence of three additives including 1- Propanone. 1-phenyl-3-[2-(phenylmethoxy)phenyl]-, p-Xylene and ethylbenzene was analyzed from MP fragments. The 48 h acute toxicity revealed that 20 % of immobilization and mortality were found at the highest concentration of PET MP (200 mg L-1). The 21 d chronic toxicity revealed that PET MP fragments significantly (p < 0.05) more reduced survival rate (31 %), total offspring (52 %) in D. magna compared with control group. The developmental abnormality of offspring (3.5%) by PET MP fragments was significantly (p < 0.05) higher than control groups (0.3%). These results are possibly induced by gut blocking by ingestion of MP fragments and their longer retention time. These findings indicate that the fragmentation of disposable cups (PET polymers) into small-sized MP fragments pose a significant ecological risk to aquatic organisms. Further studies are required to elucidate the underlying toxicity mechanisms.

CRISPR/Cas9-mediated knockout of Rag-2 causes systemic lymphopenia with hypoplastic lymphoid organs in FVB mice

  • Kim, Joo-Il;Park, Jin-Sung;Kim, Hanna;Ryu, Soo-Kyung;Kwak, Jina;Kwon, Euna;Yun, Jun-Won;Nam, Ki-Taek;Lee, Han-Woong;Kang, Byeong-Cheol
    • Laboraroty Animal Research
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    • v.34 no.4
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    • pp.166-175
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    • 2018
  • Recombination activating gene-2 (RAG-2) plays a crucial role in the development of lymphocytes by mediating recombination of T cell receptors and immunoglobulins, and loss of RAG-2 causes severe combined immunodeficiency (SCID) in humans. Rag-2 knockout mice created using homologous recombination in ES cells have served as a valuable immunodeficient platform, but concerns have persisted on the specificity of Rag-2-related phenotypes in these animals due to the limitations associated with the genome engineering method used. To precisely investigate the function of Rag-2, we recently established a new Rag-2 knockout FVB mouse line ($Rag-2^{-/-}$) manifesting lymphopenia by employing a CRISPR/Cas9 system at Center for Mouse Models of Human Disease. In this study, we further characterized their phenotypes focusing on histopathological analysis of lymphoid organs. $Rag-2^{-/-}$ mice showed no abnormality in development compared to their WT littermates for 26 weeks. At necropsy, gross examination revealed significantly smaller spleens and thymuses in $Rag-2^{-/-}$ mice, while histopathological investigation revealed hypoplastic white pulps with intact red pulps in the spleen, severe atrophy of the thymic cortex and disappearance of follicles in lymph nodes. However, no perceivable change was observed in the bone marrow. Moreover, our analyses showed a specific reduction of lymphocytes with a complete loss of mature T cells and B cells in the lymphoid organs, while natural killer cells and splenic megakaryocytes were increased in $Rag-2^{-/-}$ mice. These findings indicate that our $Rag-2^{-/-}$ mice show systemic lymphopenia with the relevant histopathological changes in the lymphoid organs, suggesting them as an improved Rag-2-related immunodeficient model.

Spatial Econometrics Analysis of Fire Occurrence According to Type of Facilities (시설물 유형에 따른 화재 발생의 공간 계량 분석)

  • Seo, Min Song;Yoo, Hwan Hee
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.37 no.3
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    • pp.129-141
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    • 2019
  • In recent years, fast growing cities in Korea are showing signs of being vulnerable to more disasters as their population and facilities increase and intensify. In particular, fire is one of the most common disasters in Korea's cities, along with traffic accidents. Therefore, in this study, we analyze what type of factors affect the fire that threatens urban people. Fire data were acquired for 10 years, from 2007 to 2017, in Jinju, Korea. Spatial distribution pattern of fire occurrence in Jinju was assessed through the spatial autocorrelation analysis. First, spatial autocorrelation analysis was carried out to grasp the spatial distribution pattern of fire occurrence in Jinju city. In addition, correlation and multiple regression analysis were used to confirm spatial dependency and abnormality among factors. Based on this, OLS (Ordinary Least Square) regression analysis was performed using space weighting considering fire location and spatial location of each facility. As a result, First, LISA (Local Indicator of Spatial Association) analysis of the occurrence of fire in Jinju shows that the most central commercial area are fire department, industrial area, and residential area. Second, the OLS regression model was analyzed by applying spatial weighting, focusing on the most derived factors of multiple regression analysis, by integrating population and social variables and physical variables. As a result, the second kind of neighborhood living facility showed the highest correlation with the fire occurrence, followed by the following in the order of single house, sales facility, first type of neighborhood living facility, and number of households. The results of this study are expected to be useful for analyzing the fire occurrence factors of each facility in urban areas and establishing fire safety measures.

Analysis of Appropriateness for Maintenance of Aged Small Bridges based on Condition and Load Carrying Capacity Evaluation (상태평가와 내하성능평가를 통한 소규모 노후교량의 유지관리 적정성 분석)

  • Lee, Huseok;Roh, Hwasung;Sun, Jong-Wan;Park, Kyung-Hoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.2
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    • pp.59-66
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    • 2019
  • Small bridges carry out only general inspections based on visual inspection. The Bridges with more than 30 years of public use need to be decided on whether or not they will be reconstruction according to aging. However, there are some situations that need to be determined only by appearance condition, which is insufficient in terms of safety maintenance. In this paper, the condition evaluation and the load carrying capacity evaluation were carried out for aged small bridges. A comparison of the evaluation results was conducted to examine the appropriateness of the maintenance related to the decision making of the reconstruction. As a result of reviewing, two of the bridges showed that there are no abnormality in the safety of the state evaluation, but the load capacity were insufficient. Thus evaluation the safety and performing the reconstruction decision of aged small bridges by visual inspection alone with may cause problems. Therefore, it is necessary to carry out additional research on the ambient measurement and load carrying capacity evaluation for the maintenance of the bridges, and to supplement it through application of the bridge management system.