• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2006.04a
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• pp.541-546
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• 2006

Recently, slope failures are happen to natural disastrous when they occur in mountainous areas adjoining highways in Korea. The accidents associated with slope failures have increased due to rapid urbanization of mountainous areas. Therefore, Regular maintenance is essential for all slope and needs maintenance of road safety as well as road function. The purpose of this paper is to recommend a standard of a $N_{10}^{\sim}$ value of Distribution of a potential failure layer using PPT(Portable penetration test).

• Journal of Ginseng Research
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• v.39 no.3
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• pp.189-198
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• 2015

Background: Antiallergic effect of 20(S)-protopanaxatriol (PPT), an intestinal metabolite of ginseng saponins, was investigated in guinea pig lung mast cells and mouse bone marrow-derived mast cells activated by a specific antigen/antibody reaction. Methods: Increasing concentrations of PPT were pretreated 5 min prior to antigen stimulation, and various inflammatory mediator releases and their relevant cellular signaling events were measured in those cells. Results: PPT dose-dependently reduced the release of histamine and leukotrienes in both types of mast cells. Especially, in activated bone marrow-derived mast cells, PPT inhibited the expression of Syk protein, cytokine mRNA, cyclooxygenase-1/2, and phospholipase $A_2$ ($PLA_2$), as well as the activities of various protein kinase C isoforms, mitogen-activated protein kinases, $PLA_2$, and transcription factors (nuclear factor-${\kappa}B$ and activator protein-1). Conclusion: PPT reduces the release of inflammatory mediators via inhibiting multiple cellular signaling pathways comprising the $Ca^{2+}$ influx, protein kinase C, and $PLA_2$, which are propagated by Syk activation upon allergic stimulation of mast cells.

• Journal of Ginseng Research
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• v.37 no.3
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• pp.300-307
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• 2013

20S-dihydroprotopanaxatriol (2H-PPT) is a derivative of protopanaxatrol from ginseng. Unlike other components from Panax ginseng, the pharmacological activity of this compound has not been fully elucidated. In this study, we investigated the modulatory activity of 2H-PPT on the cellular responses of monocytes and macrophages to understand its immunoregulatory actions. 2H-PPT strongly upregulated the release of radicals in sodium nitroprusside-treated RAW264.7 cells and the surface levels of costimulatory molecule CD86. More importantly, this compound remarkably suppressed nitric oxide production, morphological changes, phagocytic uptake, cell-cell aggregation, and cell-matrix adhesion in RAW264.7 and U937 cells in the presence or absence of lipopolysaccharide, anti-CD43 antibody, fibronectin, and phorbal 12-myristate 13-acetate. Therefore, our results suggest that 2H-PPT can be applied as a novel functional immunoregulator of macrophages and monocytes.

• The Journal of Korean Medicine
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• v.43 no.4
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• pp.1-7
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• 2022

Objectives: This study aimed to determine whether comparing the pressure pain threshold (PPT) with an algometer before and after treatment for functional dyspepsia is of diagnostic value and investigate a possible correlation between PPT measured using an algometer and symptom improvement before and after treatment. Methods: A total of 99 patients with functional dyspepsia symptoms admitted to the OO Korean Medical Hospital from April 14, 2020 to January 21, 2021 were investigated. On the 1st and 14th days of hospitalization, the pressure of the first pain complaint at acupuncture points Juque (巨厥, CV14), Shangwan (上脘, CV13), Zhongwan (中脘, CV12), Xiawan (下脘, CV10), Guanuan (關元, CV4), Tianshu (天樞, ST25), and Daju (大巨, ST27) was measured using the algometer, and the visual analog scale (VAS) scores for patient's symptoms were evaluated. The algometer PPT and patient-symptom VAS scores were compared by repeated measures corresponding to the sample t-test to analyze the changes after treatment. A correlation analysis was performed to identify the correlation between patient-symptom VAS scores and algometer PPT. Results: The PPT measured using the algometer significantly increased after treatment in the 99 patients. The patient-symptom VAS score decreased significantly in most cases as treatment progressed. Analysis of the correlation between algometer PPT and patient-symptom VAS scores revealed some notable negative correlations. Conclusion: The algometer can help to set the diagnostic and treatment baselines for patients with functional dyspepsia.

• Korean Journal of Acupuncture
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• v.40 no.3
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• pp.99-108
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• 2023

Objectives : The aim of this study was to assess the quantitative characteristics of pressure pain threshold (PPT) and pressure depth (PD) at the abdominal conception vessel (CV) acupoints according to subjective digestive status and digestive discomfort levels, accomplished by comparing a large group of healthy men and women, using the modified digital algometer. Methods : A total of 1,504 healthy adults aged 19 years or older participated in this study. A questionnaire was administered to evaluate participants' digestive status and discomfort. PPT (kgf/cm²/s) and PD (mm) measurements were obtained at CV14, CV12, and CV4 acupoints using a modified digital algometer. General characteristics were analyzed using the chi-square test, and differences in PPT and PD were assessed using two-sample t-tests and ANCOVA. Results : Significant difference in PPT was found based on digestive status at CV14 and CV12 for both sexes, and in PD at CV14 for women. Women exhibited significant difference in PPT based on digestive discomfort at CV14, CV12, and CV4, while men showed significant difference at CV14 and CV12. Significant difference in PD was observed at CV14 and CV4 among women. Even after adjusting for age and body mass index, significant difference persisted in PPT based on digestive discomfort at CV14 and CV12 for both sexes. PD exhibited significant differences at CV14, CV12, and CV4 among women. Conclusions : Using the modified digital algometer, this study showed the significant difference of pressure pain threshold at the CV14 and CV12 acupoints for subjective digestive discomfort levels in healthy men and women.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.55 no.4
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• pp.216-223
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• 2006

In this paper, a methodology for the efficiency improvement of the photovoltaic system without adding some elements or increasing the cost comparing with the conventional system is discussed. It is suggested the optimal photovoltaic module configuration through its performance analysis, and also the suitable maximum power point tracking (MPPT) voltage considered the system cost and the efficiency of the converter. The high efficiency photovoltaic system by using the parallel power transfer (PPT) based MPPT converter is proposed and analyzed theoretically comparing with the conventional Buck type MPPT converter. Finally, it is designed and implemented the proposed photovoltaic system for supplying DC 48V by using the PPT based MPPT converter. And the effect of the efficiency improvement and the usefulness of the proposed system is proved through some preliminary simulation and experiment results.

• Journal of International Academy of Physical Therapy Research
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• v.10 no.4
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• pp.1914-1920
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• 2019

Background: Mobilization and cranio-cervical flexion exercise has been reported in reducing pain from cervical part and improving its motor function; also, has been represented that alleviate of neck pain and recover of neck muscles improve the normal gait performance. However, few studies have identified the effects of mobilization and exercise on pain and gait parameters with preceding issues. Objective: To examine the effects or changes of pressure pain threshold (PPT) and gait parameters in patients with chronic neck pain. Design: Cross-Sectional Clinical Trials Methods: Twenty patients with the history of neck pain (>3 months) performed the cervical mobilization and cranio-cervical flexion exercise. Gait parameters were assessed with wireless device and collected data were transmitted to the personal computer via Bluetooth. The PPT was measured posteroanterior direction at the prone position and the mean of subsequent three PPT measurements was used for the final analysis. Results: Both cervical central posteroanterior mobilization (CCPAM) (p<.000) and sling-based cranio-cervical flexion exercise (SBCCFE) (p<.000) group showed a significant increase in the PPT and the gait parameters, cadence (p<.023), was significantly increased in the CCPAM group, however slightly increased in the SBCCFE group. The comparison between the CCPAM and the SBCCFE groups after treatment did not show significant differences for the score on the PPT and gait parameters. Conclusions: This study suggests that CCPAM and SBCCFE increase PPT, cadence, and gait speed.

• Journal of Oral Medicine and Pain
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• v.30 no.3
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• pp.345-351
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• 2005

The purpose of this double-blind study was to evaluate clinical effects of botulinum toxin type A (BTX-A) injection on myofascial pain syndrome (MPS) involving upper trapezius and compare with those of lidocaine injection. 21 patients presenting with active TrP1 and/or TrP2 in the upper trapezius over 6 months were selected for this study. The subjects were randomly divided into two groups; one group injected with BTX-A (15 unit of $Botox^{(R)}$ / 0.3 ml per trigger point (TrP)) and the other group injected with 0.5% lidocaine (0.3 ml /TrP). The clinical effects were evaluated by VAS and PPT at baseline, 2, 4, 6 and 8 weeks after treatment. BTX-A group showed persistent decrease of VAS values and increase of PPT values following treatment. While there was no significant difference in VAS values between BTX-A and lidocaine groups (p=0.347), there was significant difference in PPT values after treatment between two groups (p=0.000). The subjects received BTX-A showed noticeable improvement in PPT values after treatment, suggesting more reliable effect of BTX-A injection compared with lidocaine injection. The results of this study support that the direct injection of BTX-A to a TrP is an effective and safe treatment for MPS involving upper trapezius.

• Journal of Plant Biotechnology
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• v.44 no.1
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• pp.82-88
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• 2017

Transgenic lily plants have been obtained after particle bombardment, using PDS-1000/He system and scale explants of lilies, followed by PPT (D-L-phosphinothricin) selection. In this study, scales of the lily plants cv. 'red flame' were bombarded with a plasmid containing the bar gene as a selectable marker, and the AtSIZ gene as a gene of interest, showing salt tolerance and drought tolerance respectively, and both being driven by the CaMV 35S promoter. For optimization of a protocol, factors which optimized and showed a high transformation efficiency under following conditions, were considered: a bombardment pressure of 1100 psi, a target distance of 6 cm and $1.0{\mu}m$ of gold particle, and 24-h pre-culture and post-culture on MS medium containing 0.2 M sorbitol and 0.2 M mannitol as osmoticum agents. After bombardment, all the bombarded scales of lily were transferred to MS medium without selective agents, for a week. Subsequently, these bombarded scales were transferred to a selection MS medium containing 10 mg/l PPT, and incubated for a month for further selection, after which they were cultured for another 4-8 weeks with a 4-week subculture regime on the same selection medium. After transferring into hormone-free MS medium, the PPT-resistant scales with shoots were successfully rooted and regenerated into plantlets. PCR analysis revealed that the surviving putatively transformed plantlets indicated the presence of both the bar gene and the AtSIZ gene. In conclusion, when 100 scales of lily cv. Red flame are bombarded, this study produced approximately 17-18 transgenic plantlets with an optimized bombardment protocol. The protocol described here can contribute to the breeding program of lilies.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.45 no.8
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• pp.697-703
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• 2017

A teflon ionization modeling has been conducted to predict the performance of a PPT(Pulsed Plasma Thruster). One dimensional unsteady circuit model and Teflon ablation model were implemented. The Saha equation was adapted to predict the ionization of Carbon and Fluorine gas. The lumped circuit model including a resistance and a inductance model of a plasma was adapted to predict the magnitude of a discharge current. Numerical simulation results had good agreements with pervious research. The degree of current change according to PPT operating voltage was examined.