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Evaluation of dose delivery accuracy due to variation in pitch and roll (세기변조방사선치료에서 Pitch와 Roll 변화에 따른 선량전달 정확성 평가)

  • Jeong, Chang Young;Bae, Sun Myung;Lee, Dong Hyung;Min, Soon Ki;Kang, Tae Young;Baek, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.2
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    • pp.239-245
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    • 2014
  • Purpose : The purpose of this study is to verify the accuracy of dose delivery according to the pitch and roll rotational setup error with 6D robotic couch in Intensity Modulated Radiation Therapy (IMRT) for pelvic region in patients. Materials and Methods : Trilogy(Varian, USA) and 6D robotic couch(ProturaTM 1.4, CIVCO, USA) were used to measure and analyze the rotational setup error of 14 patients (157 setup cases) for pelvic region. The total 157 Images(CBCT 78, Radiography 79) were used to calculate the mean value and the incidence of pitch and roll rotational setup error with Microsoft Office Excel 2007. The measured data (3 mm, 3%) at the reference angle ($0^{\circ}$) without couch rotation of pitch and roll direction was compared to the others at different pitch and roll angles ($1^{\circ}$, $1.5^{\circ}$, $2^{\circ}$, $2.5^{\circ}$) to verify the accuracy of dose delivery by using 2D array ionization chamber (I'mRT Matrixx, IBA Dosimetry, Germany) and MultiCube Phantom(IBA Dosimetry, Germany). Result from the data, gamma index was evaluated. Results : The mean values of pitch and roll rotational setup error were $0.9^{\circ}{\pm}0.7$, $0.5^{\circ}{\pm}0.6$. The maximum values of them were $2.8^{\circ}$, $2.0^{\circ}$. All of the minimum values were zero. The mean values of gamma pass rate at four different pitch angles ($1^{\circ}$, $1.5^{\circ}$, $2^{\circ}$, $2.5^{\circ}$) were 97.75%, 96.65%, 94.38% and 90.91%. The mean values of gamma pass rate at four different roll angles ($1^{\circ}$, $1.5^{\circ}$, $2^{\circ}$, $2.5^{\circ}$) were 93.68%, 93.05%, 87.77% and 84.96%. when the same angles ($1^{\circ}$, $1.5^{\circ}$, $2^{\circ}$) of pitch and roll were applied simultaneously, The mean values of each angle were 94.90%, 92.37% and 87.88%, respectively. Conclusion : As a result of this study, it was able to recognize that the accuracy of dose delivered is lowered gradually as pitch and roll increases. In order to increase the accuracy of delivered dose, therefore, it is recommended to perform IGRT or correct patient's position in the pitch and roll direction, to improve the quality of treatment.

Double Tension Band Osteosynthesis in Intra-articular Fractures of the Distal Humerus (AO type C) in Elderly Osteoporotic Patients (고령 환자의 상완골 원위부 AO-C형 골절에서 이중 강선 장력대 고정술)

  • Cheon, Sang Jin;Lee, Dong Ho;Goh, Tae Sik
    • Clinics in Shoulder and Elbow
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    • v.16 no.1
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    • pp.33-39
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    • 2013
  • Purpose: The aim of this study is to evaluate the clinical result of intra-articular fractures of the distal humerus (AO type C) in elderly osteoporotic patients treated with double tension band osteosynthesis. Materials and Methods: From January 2006 to December 2010, 10 elderly osteoporotic patients(1 male, 9 females) with intra-articular fractures of the distal humerus (AO type C) were treated with double tension band osteosynthesis. The mean age of patients at the time of surgery was 74.6(66~84) years and the mean follow-up period was 39.2(20~74) months. The fracture union and complications were assessed and the functional result was evaluated by the rating system of Jupiter et al. and the Mayo elbow performance index. Results: Bone union was achieved in all patients with no secondary displacement. The mean time for union was 16.6(13~22) weeks. The average postoperative arc of elbow flexion was 119(100~140) degrees with a mean flexion contracture of 8.5(0~15) degrees. The recovery in two patients was rated as excellent, in 7 as good, and in 1 as fair in terms of the Mayo elbow performance index with average value of 82(70~90) points. Seven patients were rated as excellent, 1 as good, and 2 as fair in terms of the rating system of Jupiter et al. Changing tension band wiring was performed in one patient as skin irritation was noticed due to tension band knots. Heterotopic ossification developed in one patient but had no symptom. Conclusion: Double tension band osteosynthesis in intra-articular fractures of distal humerus (AO type C) in elderly osteoporotic patients can provide sufficient and secure stability to allow early rehabilitation.

Effect of different pattern size and pattern shape on castability of commercially pure titanium (납형의 크기와 형태가 티타늄의 주조성에 미치는 영향)

  • Seo, Yoon-Jeong;Oh, Gye-Jeong;Lee, Hyo-Il;Shin, Yoo-Jin;Kim, Hong-Joo;Park, Sang-Won
    • The Journal of Korean Academy of Prosthodontics
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    • v.51 no.4
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    • pp.261-268
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    • 2013
  • Purpose: The purpose of this study was to investigate the effect of geometrically different wax pattern shapes and sizes on the castability of Grade2 Cp-Ti (commercially pure titanium). Materials and methods: Total of 40 mesh wax pattern ($61mm{\times}24mm$, 207 grids), ($61mm{\times}17mm$, 138 grids) was cast in this experiment. Depending on the geometrical shape of the wax pattern, 8 groups was organized; Flat, Semicircular, Horse-shoe and V-shape, each consisting 5 samples. Runner-bar sprue was used in all patterns. The number of completely cast grid in wax pattern served as a measure for the castability of comercially pure titanium. Results: The mean value of square count in each group was as followed; 133.20 squares in group SS (96.52%), 132.40 squares in group SH (95.94%), 132.00 squares in group SF (95.65%), 127.60 squares in SV (91.43%), 198.60 squares in group LF (95.94%), 197.80 squares in group LV (95.56%), 196.40 squares in group LS (94.88%), and 188.00 squares in group LH (90.82%). Conclusion: Within the limitations of this study the results indicate that there were no sttistically significant difference in castability of titanium regarding wax pattern shape (P>.05). However, Small size wax patterns were showing the noticeable castability more than Large size pattern.

Status and Change in Chemical Properties of Polytunnel Soil in Korea from 2000 to 2012

  • Kang, Seong Soo;Roh, Ahn Sung;Choi, Seung Chul;Kim, Young Sang;Kim, Hyun Ju;Choi, Moon Tae;Ahn, Byoung Gu;Kim, Hee Kwon;Park, Sang Jo;Lee, Young Han;Yang, Sang Ho;Ryu, Jong Soo;Sohn, Yeon Gyu;Kim, Myeong Sook;Kong, Myung Suk;Lee, Chang Hoon;Lee, Deog Bae;Kim, Yoo Hak
    • Korean Journal of Soil Science and Fertilizer
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    • v.46 no.6
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    • pp.641-646
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    • 2013
  • Chemical properties of agricultural soils in Korea have been investigated at four-year interval in order of paddy, polytunnel, upland, and orchard soils since 1999; polytunnel soils were investigated over the whole country in 2000, 2004, 2008, and 2012. Polytunnel soils were taken from the surface (0-15 cm) and subsurface (15-30 cm) at 2,651, 1,274, 1,374 and 1,374 sites in all provinces of South Korea. One hundred sampling sites located in more than 400 m altitude were additionally investigated in 2008 and 2012. Average of soil chemical properties in 2012 except Jeju province were 6.6 for pH, 3.2 dS $m^{-1}$ for EC, 37 g $kg^{-1}$ for organic matter (OM), 1,049 mg $kg^{-1}$ for available (Avail.) phosphate, 1.58 $cmol_c\;kg^{-1}$ for exchangeable (Exch.) K, 10.6 $cmol_c\;kg^{-1}$ for Exch. Ca, and 3.3 $cmol_c\;kg^{-1}$ for Exch. Mg. Except pH, averages of all chemical properties exceeded the upper limit of optimal range. The median values except pH showed a lower value than the averages. The pH, OM and Exch. Ca had slightly increased from 6.3 to 6.6, from 34 to 37 g $kg^{-1}$, and from 7.7 in 2000 to 10.6 $cmol_c\;kg^{-1}$ in 2012, respectively. The order of sample ratios exceeding the optimal range were Avail. $P_2O_5$ (83%) > Exch. Ca (80%) > Exch. K (70%) > Exch. Mg (65%) > EC (55%) > OM (48%) > pH (29%) in 2012. The order of sample ratios below the optimal range was OM (25%) > Exch. K (25%) > pH (20%), Exch. Mg and Avail. $P_2O_5$ (9%) > Exch. Ca (6%) in 2012. The excessive proportion of pH, Exch. Ca, Exch. Mg and OM slightly increased, while the insufficient proportion of those decreased. Approximately 55% of polytunnel soils exceeding EC 2 dS $m^{-1}$ was evaluated with salt accumulated soils having the risk of growth disorder of crops. Nutrient contents in polytunnel soils in Korea showed high level especially Avail. $P_2O_5$ and Exch. cations. Therefore, recommended fertilization based on soil testing or plant testing is needed for soil nutrient management.

A Method to Quantify Breast MRI for Predicting Tumor Invasion in Patients with Preoperative Biopsy- Proven Ductal Carcinoma in Situ (DCIS) (유방 자기공명영상법을 이용한 수술 전 관상피내암으로 진단된 환자의 침윤성 유방암을 예측하는 정량적 분석법)

  • Ko, Myung-Su;Kim, Sung Hun;Kang, Bong Joo;Choi, Byung Gil;Song, Byung Joo;Cha, Eun Suk;Kiraly, Atilla Peter;Kim, In Seong
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.2
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    • pp.73-82
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    • 2013
  • Purpose : To determine the quantitative parameters of breast MRI that predict tumor invasion in biopsy-proven DCIS. Materials and Methods: From January 2009 to March 2010, 42 MRI examinations of 41 patients with biopsy-proven DCIS were included. The quantitative parameters, which include the initial percentage enhancement ($E_1$), peak percentage enhancement ($E_{peak}$), time to peak enhancement (TTP), signal enhancement ratio (SER), arterial enhancement fraction (AEF), apparent diffusion coefficient (ADC) value, long diameter and the volume of the lesion, were calculated as parameters that might predict invasion. Univariate and multivariate analyses were used to identify the parameters associated with invasion. Results: Out of 42 lesions, 23 lesions were confirmed to be invasive ductal carcinoma (IDC) and 19 lesions were confirmed to be pure DCIS. Tumor size (p = 0.003; $6.5{\pm}3.2$ cm vs. $3.6{\pm}2.6$ cm, respectively) and SER (p = 0.036; $1.1{\pm}0.3$ vs. $0.9{\pm}0.3$, respectively) showed statistically significant high in IDC. In contrast, E1, Epeak, TTP, ADC, AEF and volume of the lesion were not statistically significant. Tumor size and SER had statistically significant associations with invasion, with an odds ratio of 1.04 and 22.93, respectively. Conclusion: Of quantitative parameters analyzed, SER and the long diameter of the lesion could be specific parameter for predicting invasion in the biopsy-proven DCIS.

Evaluation of Fish Acute Toxicity and Preliminary Risk Assessment of Plant Extracts, Sophora, Neem and Derris (유기농업자재 고삼, 님 및 데리스 추출물의 어류에 대한 독성과 위해성 평가)

  • Park, Kyung-Hun;Oh, Jin-A;Paik, Min-Kyoung;Son, Mi-Yeon;Lim, Joung-Taek;Jin, Jung-hwa;Hong, Soonsung;Cho, Nam-jun;Han, Sang-Gyun;Kim, Byung-Seok
    • The Korean Journal of Pesticide Science
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    • v.19 no.3
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    • pp.255-263
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    • 2015
  • Promoting the organic farming, much of the plant extracts used for controlling pests and fungi have been imported from China, India and Myanmar. But, it is so worrisome that aquatic animals such as muddy loach inhabiting in paddy field and common carps in river exposed to the pests and fungi likely be harmed. This study was conducted in order to evaluate the risks of aquatic animals influenced by the three plant extracts, i.e. Sophora flavescens, Azadirachta indica and Derris elliptica. The toxicities of common carp (Cyprinus Carpio), muddy loach (Misgurnus anguillicaudatus) and PEC (Predicted environmental concentration) exposed to the three plant extracts were estimated by the typical spray volume method. Risks were determined by the toxicity value as 48-hr $LC_{50}$ (Lethal concentration, median) or NOEC (No observed effect concentration) into PEC. 48-hr $LC_{50}$ of Common carp and NOEC by Sophora flavescens extracts was 7.9 and 6.2 mg/L, 26.8 and 21.8 mg/L by Azadirachta indica extracts and 47.0 and < 24.0 mg/L by Derris elliptica extracts, respectively. 48-hr $LC_{50}$ of Muddy loach and NOEC by Sophora flavescens extracts was 16.9 and 10.0 mg/L, 35.6 and 30.0 mg/L by Azadirachta indica extracts, and 73.9 and < 40 mg/L by Derris elliptica extracts, respectively. Therefore, acute toxicities of the three plant extracts for aquatic animals were proved to be very low level. PEC of Sophora flavescens extracts in paddy, drainage and river water was 68.0~3.0, 11.33~0.50 and 3.0~0.0018 mg/L, respectively. TER of Sophora flavescens extracts in the three water was 0.2~5.6, 1.5~33.8 and 2.6~4388.9, respectively. PEC of Azadirachta indica extracts in paddy, drainage and river water was 90.9~1.2, 15.2~0.2 and 4.8~0.00075 mg/L, respectively. TER of Azadirachta indica extracts in the three water was 0.4~29.7, 2.3~178.0 and 4.5~35733.3, respectively. PEC of Derris elliptica extracts in river water was 0.0063 mg/L. TER of Derris elliptica extracts in river water was 5222~15667.

Soil Contamination of Heavy Metals in National Industrial Complexes, Korea (국내 주요 국가산업단지에서 중금속에 의한 토양오염)

  • Jeong, Tae-Uk;Cho, Eun-Jeong;Jeong, Jae-Eun;Ji, Hwa-Seong;Lee, Kyeong-Sim;Yoo, Pyung-Jong;Kim, Gi-Gon;Choi, Ji-Yeon;Park, Jong-Hwan;Kim, Seong-Heon;Heo, Jong-Soo;Seo, Dong-Cheol
    • Korean Journal of Environmental Agriculture
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    • v.34 no.2
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    • pp.69-76
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    • 2015
  • BACKGROUND: Contamination of soils by heavy metals is the serious environmental problem. In particular, industrial processing is one of the main sources of heavy metal contamination. The objective of this study was to investigate the distribution characteristics of heavy metals in soils collected from industrial complex. METHODS AND RESULTS: In this study, the soil contamination and enrichment factor (EF) of heavy metals were investigated in three national industrial complexes such as Yeosu, Ulsan and Sihwa Banwal industrial complexes. The target heavy metals includes Cd, Cu, As, Hg, Pb, Cr, Zn, and Ni. The results showed that the contents of Cd, Hg, Pb, Zn and Ni in Yeosu and the contents of Cu, As and Cr in Sihwa Banwal were higher than in any other industrial complex. The results of principal component analysis(PCA) in Yeosu, Ulsan and Sihwa Banwal complex could be explained up to approximately 81.4, 69.1 and 70.9% by two factor, respectively. Enrichment factors of Cd, Pb and Zn in all the investigated industrial complexes were above 1.0 that was the value judged to be a high contamination. And EF of Cr was above 1.0 in Sihwa Banwal complex. EF of Zn in all sites was generally high from the other heavy metals. CONCLUSION: Therefore, soils maybe significantly affected by heavy metals (especially, Cd, Pb and Zn) present in the emissions from industrial complexes.

The Effect of Liquid Pig Manure on Yield of Several Forage Crops and Soil Chemical Properties (돈분액비 시용이 동·하계 사료작물의 수량 및 토양의 화학적 특성에 미치는 영향)

  • Cho, Kwang-Min;Lee, Sang-Bok;Back, Nam-Hyun;Yang, Chang-Hyu;Shin, Pyung;Lee, Kyeong-Bo;Park, Ki-Hoon;Baek, Seung-Hwa
    • Korean Journal of Environmental Agriculture
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    • v.32 no.4
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    • pp.323-331
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    • 2013
  • BACKGROUND: Liquid pig manure(LPM) is a useful resource if it is sufficiently fermented and utilized in the agriculture; it provides nutrients to soils, circulates organic materials and replaces chemical fertilizers(CF) with reasonable costs. Currently, there are not many trials in paddy field to continuously cultivate the crops in winter and summer season using LPM. METHODS AND RESULTS: When cultivating winter forage crops (Whole-crop-barley(WCB), Rye, Triticale, Italian ryegrass(IRG)) and summer feed corns in the rice field, CF was treated with $N-P_2O_5-K_2O$(winter forage crops: 120-100-100kg/ha, summer feed corn: 200-150-150 kg/ha), and subsequently, growth, yields, feed values and chemical properties of soil were investigated. LPM-applied areas in both winter and summer forage crops showed higher plant lengths and tillers than those of CF-applied areas, but the yield in CF-applied areas was higher than that of LPM-applied areas under continuous application of 2 years. Crude protein, neutral detergent fiber(NDF), acid detergent fiber(ADF) and total digestion nutrient(TDN) in feed values showed almost similar results between LPM and CF-applied areas. EC, organic matter, available phosphate and exchangeable cations of soils after the experiment increased in LPM applied areas, and especially, the contents of available phosphate and exchangeable sodium were high. CONCLUSION(S): Considering the above results, it was concluded that if LPM are properly utilized for continuous winter and summer cultivation of feed crops at paddy field, the cultivation costs could be decreased and be helpful to the stable production of domestic feeds.

Effect of Several Treatments on Chilling Injury of Paprika Fruits during Low Temperature Storage (몇 가지 처리가 파프리카 과실의 저온장해에 미치는 영향)

  • Choi, In-Lee;Lee, Yong Beom;Kim, Il Seop;Baek, Jun Pill;Kang, Ho-Min
    • Journal of Bio-Environment Control
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    • v.22 no.4
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    • pp.427-431
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    • 2013
  • Paprika fruits should be stored and distributed at above $7^{\circ}C$ to prevent chilling injury but the small amount of paprika that transports with other horticultural products in refrigerated container by ship usually stored less than $5^{\circ}C$ for other products. In this case, paprika fruits cannot help exposing chilling temperature, so that the paprika must be lost marketable value during a long period of transfer. This study was conducted to compare the alleviated effects of high $CO_2$ treatment (passive MAP), heat (hot water dipping), and UVc treatment on chilling injury of paprika fruits due to low temperature storage, and also to decide if these treatments can be used for transporting under $5^{\circ}C$. After each treatment the paprika were put in the low temperature storage ($4^{\circ}C$) for 20 days and afterwards change the in room temperature ($20^{\circ}C$) for 5 days. The fresh weight loss of all the treatments except the high $CO_2$ treatment showed around 7~12% after 25 days of storage and the ethylene concentration showed periodical increases and decreases as around 3 ${\mu}l/l$. The $CO_2$ concentration was rapidly increased 33% carbon dioxide in high $CO_2$ treatment during room temperature storage after cold storage for 20 days. The firmness which is key quality characteristics during storage and is decreasing caused by chilling injury was not significantly different among all treatments. However, the firmness of stored paprika was maintained highest in the treated with hot water dipping. Therefore, HWD and UVc treatment that showed 60% of electrolyte leakage in the $4^{\circ}C$ control (chilling injury control) and similar level with the $7^{\circ}C$ control (non-chilling injury control) would be effective to alleviate chilling injury in the stored paprika.

Effects of Terpenoids-Rich Plant Extracts on Ruminal-fermentation and Methane Production (Terpenoid 함유 식물 추출물의 첨가가 반추위 발효와 메탄 발생에 미치는 영향)

  • Hwang, Hee-Soon;Ha, Dong-Uk;Lee, Su-Kyoung;Lee, Il-Dong;Lee, Shin-Ja;Lee, Sung-Sill
    • Korean Journal of Organic Agriculture
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    • v.21 no.4
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    • pp.629-646
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    • 2013
  • This study was conducted to investigate effects of terpenoids-rich plant extracts (TRPE) on the in vitro ruminal fermentation characteristics and methane production. The ruminal fluid was collected from a cannulated Hanwoo cow fed concentrate and timothy in the ratio of 6 to 4. The TRPE as Mint (Mentha arvensis var. piperascens), Pine (Pinus densiflora), Japan cedar (Cryptomeria japonica), Sichuan pepper (Zanthoxylum piperitum), Hinoki cypress (Chamaecyparis obtuse) and Japanese black pine (Pinus thunbergii) were used in this study. The 15 mL of mixture, contains McDougall buffer and rumen fluid in the ratio of 2 to 1. The mixture was dispensed anaerobically 50 mL serum bottles and it is contained 0.3 g timothy substrate and 5% TRPE. The bottles were incubated at $39^{\circ}C$ for 3, 6, 9, 12, 24, 48 and 72 hours. The pH value decrease by increased incubation times and the pH values at all times were significantly (p<0.05) higher in treatments than in control. The digestibility of dry matter at 3 hours was significantly (p<0.05) higher in mint treatment than in control. Productions of total gas and carbon dioxide at before 12 hours was significantly lower (p<0.05) in treatments than in control. The methane production at 24 hours was significantly (p<0.05) lower in treatments than in control. The concentrations of acetic acid and propionic acid at 24 hours were significantly higher (p<0.05) in mint and pine treatments than in control. In conclusion, the terpenoid-rich plant extracts were shown to decreased methane emission and without adversely affected ruminal fermentation. Therefore, the terpenoid-rich plant extracts as mint and pine were shown to decreased methane production and it has potential possibility for ruminal fermentations.