• Journal of the Korean Society of Radiology
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• v.17 no.2
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• pp.207-213
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• 2023

Computed tomography (CT) images are used as the basis for proton Bragg peak position estimation and treatment plan simulation. During the Hounsfield Unit (HU) based proton stopping power ratio (SPR) estimation, small differences in the patient's density and elemental composition lead to uncertainty in the Bragg peak positions along the path of the proton beam. In this study, we investigated the potential of dual-energy computed tomography image-based proton SPRs prediction accuracy to reduce the uncertainty of Bragg peak position prediction. Single- and dual-energy images of an electron density phantom (CIRS Model 062M electron density phantom, CIRS Inc., Norfolk, VA, USA) were acquired using a computed tomography system (Somatom Definition AS, Siemens Health Care, Forchheim, Germany) to estimate the SPRs of the proton beam. To validate the method, it was compared to the SPRs estimated from standard data provided by the National Institute of Standards and Technology (NIST). The results show that the dual-energy image-based method has the potential to improve accuracy in predicting the SPRs of proton beams, and it is expected that further improvements in predicting the position of the proton's Bragg peak will be possible if a wider variety of substitutes with different densities and elemental compositions of the human body are used to predict the SPRs.

• Journal of the Korean Mathematical Society
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• v.60 no.2
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• pp.407-464
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• 2023

Let R be a commutative ring with identity. The structure theorem says that R is a PIR (resp., UFR, general ZPI-ring, π-ring) if and only if R is a finite direct product of PIDs (resp., UFDs, Dedekind domains, π-domains) and special primary rings. All of these four types of integral domains are Krull domains, so motivated by the structure theorem, we study the prime factorization of ideals in a ring that is a finite direct product of Krull domains and special primary rings. Such a ring will be called a general Krull ring. It is known that Krull domains can be characterized by the star operations v or t as follows: An integral domain R is a Krull domain if and only if every nonzero proper principal ideal of R can be written as a finite v- or t-product of prime ideals. However, this is not true for general Krull rings. In this paper, we introduce a new star operation u on R, so that R is a general Krull ring if and only if every proper principal ideal of R can be written as a finite u-product of prime ideals. We also study several ring-theoretic properties of general Krull rings including Kaplansky-type theorem, Mori-Nagata theorem, Nagata rings, and Noetherian property.

• Korean Journal of Chemical Engineering
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• v.36 no.6
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• pp.975-980
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• 2019

Infrared (IR) spectroscopy is a powerful technique for observing organic molecules, as it combines sensitive vibrational excitations with a non-destructive probe. However, gaseous volatile compounds in the air are challenging to detect, as they are not easy to immobilize in a sensing device and give enough signal by themselves. In this study, we fabricated a thin nanocrystalline metal-organic framework (nMOF) film on a surface plasmon resonance (SPR) substrate to enhance the IR vibration signal of the gaseous volatile compounds captured within the nMOF pores. Specifically, we synthesized nanocrystalline HKUST-1 (nHKUST-1) particles of ca. 80 nm diameter and used a colloidal dispersion of these particles to fabricate nHKUST-1 films by a spin-coating process. After finding that benzene was readily adsorbed onto nHKUST-1, an nHKUST-1 film deposited on a plasmonic Au substrate was successfully applied to the IR detection of gaseous benzene in air using surface-enhanced IR spectroscopy.

• Journal of Korean Library and Information Science Society
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• v.31 no.2
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• pp.63-91
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• 2000

In ths study, I proposed the need for strengthening the information analysis function of research library whch is in charge of knowledge control in a company based on knowledge management. In the operating steps of information management for a company, 1 studed about providmg analyzed dormation at the level of a professional in various forms through intranet within a company after processing and analyzing the collected raw lnformation to make customized lnformation according to the need of each group, rather than passively providing information as required by users. By establishmg the senior decision-making person within the company as the core user in contrast with information s e ~ c e spr ovided in large libraries, ths will give us a new position as lnformation manager, who can accomplish tlie corporate goal. Also, I proposed the details for becoming a pioneer in knowledge management system.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.110-111
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• 2013

FcBP consisting of 13 amino acids specifically binds to Immunoglobulin G Fc domain. Initially, we utilized this peptide for preparation of antibody chip as a PEG composite for enhanced solubility. After then, the peptide conjugate was immobilized on agarose resin, resulting in highly efficient affinity column for antibody purification. The efficiency was comparable to commercial Protein A column. Recently, this peptide was conjugated with cell penetrating peptide (CPP) on a backbone of GFP, affording antibody transducer, which carries antibody into live cells by simple mixing of antibody and the transducer in cell culture media. Antibody transduction into cells was monitored by live cell imaging. More recently, the FcBP was fused to ferritin cage, which consists of 24 ferritin protein molecules. The FcBP-ferritin cage showed greatly increased binding affinity to human IgG. Its binding was analyzed by QCM and SPR analysis. Finally, it was selectively delivered by Herceptin to SKBR3, a breast cancer cell, over MCF10A, non-tumorigenic cells (Fig. 1). Fig. 1. Fluorescent microscopic images of SKBR3 breast cancer cells (A~C) and MCF10A breast cells (D~F) treated with Cy3-trastuzumab/fFcBP-Pf_Fn complexes. Trastuzumab and FcBP-Pf_Fn, which were labeled with Cy3 (Cy3-trastuzumab) and fluorescein (fFcBP-Pf_Fn), respectively, selectively targeted SKBR3 over MCF10A.

• Journal of the Korean Wood Science and Technology
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• v.43 no.2
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• pp.258-264
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• 2015

To evaluate the influence of 3A zeolite on the flame retardant properties of poplar plywood. Ammonium polyphosphate (APP) and 3A zeolite were used as flame retardants to prepare plywood samples. The combustion properties, such as heat release rate (HRR), total heat release (THR), mean CO and $CO_2$ yield, smoke production rate (SPR), and total smoke production (TSP), were characterized by a cone calorimeter. A synergistic effect was observed between 3A zeolite and APP on reducing the HRR and mean CO yield. The probable flame retardation mechanism was proposed.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2008.11a
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• pp.66-66
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• 2008

본 연구에서는 ITO/Ag/ITO 다층 박막을 유기발광소자와 플렉시블 광전소자의 전극으로 적용하기 위하여 선형 대항 타겟 스퍼터(Linear facing target sputter) 시스템을 이용하여 성막하였고, ITO/Ag/ITO 다층박막의 전기적, 광학적, 구조적 특성을 분석하였다. 선형 대항 타겟 스퍼터 시스템은 강한 일방항의 자계와 타겟에 걸린 음극에 의해 전자의 회전, 왕복 운동이 가능해 마주보는 두 ITO 타겟 사이에 고밀도의 플라즈마를 구속 시켜 플라즈마 데미지 없이 산화물 박막을 성막시킬 수 있는 장치이다. 대항 타겟 스퍼터 시스템을 이용하여 성막한 ITO 전극을 DC power, working pressure, Ar/O2 ratio 에 따른 특성을 각각 분석하였다. glass 기판위에 최적화된 ITO 전극을 bottom layer로 두고, bottom ITO layer 위에 thermal evaporation 을 이용하여 Ag 박막을 6~20nm의 조건에 따라 두께를 다르게 성막하고, Ag 박막을 성막한 후에 다시 bottom ITO 전극과 같은 조건으로 ITO 전극을 top layer로 성막 하였다. 두 비정질의 ITO 전극 사이에 매우 앓은 Ag 박막을 성막 함으로 해서 glass 기판위에 ITO/Ag/ITO 다층 박막전극은 매우 낮은 저항과 높은 투과도를 나타낸다. ITO/Ag/ITO 박막의 전기적 광학적 특성을 보기 위해 hall measurement와 UV/visible spectrometer 분석을 각각 진행하였다. ITO/Ag/ITO 다층 박막 전극이 매우 얇은 두께임에도 불구하고 $4\Omega$/sq.의 낮은 면저항과 85%의 높은 투과도를 나타내는 이유는 ITO/Ag/ITO 전극 사이에 있는 Ag층의 표면 플라즈몬 공명 (SPR) 현상으로 설명할 수 있다. ITO/Ag/ITO 전극의 Ag의 거동을 분석 하기위해 FESEM분석과 synchrotron x-ray scattering 분석을 하였다. ITO/Ag/ITO 전극의 Ag층이 islands의 모양에서 연속적으로 연결되는 변화과정 중에 SPR현상이 일어남을 알 수 있다. 여기서, 대항 타겟 스퍼터 시스템을 이용하여 성막한 ITO/Ag/ITO 다층박막을 OLED 또는 inverted OLEDs의 top 전극으로의 적용 가능성을 보이고 있다.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2003.04a
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• pp.288-295
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• 2003

An adaptive procedure in finite element analysis is presented by p-refinement of meshes in conjunction with a posteriori error estimator that is based on the recovery technique. In case of the recovery technique, the SPR(superconvergent patch recovery) approach has been modified for p-adaptive mesh refinement. The strategy of finding a nearly optimal distribution of polynomial degrees on a fixed finite element mesh is discussed such that a particular element has to be refined automatically to obtain an acceptable level of accuracy by increasing p-levels non-uniformly. To verify the proposed algorithm, the limit value approach is proposed which utilizes the exact strain energy computed from the extrapolation equation. A new pre-processor is developed for the p-version finite element program in which the vector graphic editor is used for the automatic generation of node connection and coordinate by halfedge solid data structure according to uniform or nonuniform p-distribution. The general 2-D algorithm is also developed to generate face modes and internal modes in accordance with different mesh types. The quality of the error estimator is investigated with the help of two mumerical examples. The results show that the sequences of p-distributions obtained by the proposed error indicator closely follow the optimal trajectory.

• Journal of Microbiology and Biotechnology
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• v.25 no.1
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• pp.50-56
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• 2015

During pretreatment of lignocellulosic biomass, a variety of fermentation inhibitors, including acetic acid and vanillin, are released. Using DNA microarray analysis, this study explored genes of the budding yeast Saccharomyces cerevisiae that respond to vanillin-induced stress. The expression of 273 genes was upregulated and that of 205 genes was downregulated under vanillin stress. Significantly induced genes included MCH2, SNG1, GPH1, and TMA10, whereas NOP2, UTP18, FUR1, and SPR1 were down regulated. Sequence analysis of the 5'-flanking region of upregulated genes suggested that vanillin might regulate gene expression in a stress response element (STRE)-dependent manner, in addition to a pathway that involved the transcription factor Yap1p. Retardation in the cell growth of mutant strains indicated that MCH2, SNG1, and GPH1 are intimately involved in vanillin stress response. Deletion of the genes whose expression levels were decreased under vanillin stress did not result in a notable change in S. cerevisiae growth under vanillin stress. This study will provide the basis for a better understanding of the stress response of the yeast S. cerevisiae to fermentation inhibitors.

• 한국신재생에너지학회:학술대회논문집
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• 2006.06a
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• pp.121-124
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• 2006

In the newly developed control method, the current flowing into SPE cell is the only one considerable factor. So, the structure of control circuit becomes simple and the manufacturing cost of the control device decreases. In conventional power comparison MPPT control method however, a voltage and current coming out from PV cell should be feedbacked to chase maximum power point at every moment. Then, the structure of control circuit becomes so complex and the risk of control failure is much higher than the novel MPPT control method. Therefore, PV generation system by a novel MPPT control method is especially operated much more safely in case of a huge system, because the voltage coming out from PV-cell is not needed to be feedbacked. In this paper, the PV-SPR system was actually manufactured based on the simulation model of PSCAD/EMTDC program and the results tested were shown. Authors are sure that it is the most useful method to maximize power from PV to SPE with only a feedback of SPE input current.