• Title/Summary/Keyword: a DTS

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Antifungal Effect of Tanshinone from Salvia miltiorrhiza against Disseminated Candidiasis (Tanshinone 단삼성분의 전신성 캔디다증에 대한 항균효과)

  • Han, Yongmoon;Joo, Inkyung
    • YAKHAK HOEJI
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    • v.57 no.2
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    • pp.119-124
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    • 2013
  • The aim of this present study was to investigate the antifungal effect of tanshinones isolated from Salvia miltiorrhiza against Candida ablicans, a polymorphic fungus. For the work, tanshinone IIA (TSN), cryptotanshinone (CTS), and dihydrotanshinone I (DTS) were chosen. Initially, their antifungal effect was analyzed by in-vitro susceptibility test. Data from the susceptibility test showed that while all of these three compounds had antifungal activity, DTS was the most potent. At $100{\mu}g$ DTS/ml, there was about 80% CFU (colony forming unit) reduction as compared to DTS-untreated C. albicans yeast cells (P<0.05). Thus, DTS was selected to determine its antifungal activity in a murine model of disseminated candidiasis due to C. albicans. Results showed that DTS enhanced resistance of mice against disseminated candidiasis. During the entire period of 30-day observation, 60% of DTS-given mice groups survived whereas control animals all died within 14 days (P<0.05). Moreover, DTS inhibited the hyphal production, one of the virulence factors of this fungus, from the blastoconidial form of the fungus. Therefore, the tanshinone appears to have antifungal activity specific for C. albicans infection, which could possibly be mediated by the blockage of hyphal production.

Digital Tomosynthesis versus Conventional Radiography for Evaluating Osteonecrosis of the Femoral Head

  • Yun Hwa Roh;Seunghun Lee;Jeong Ah Ryu;Yeo Ju Kim;Yeesuk Kim;Jiyoon Bae
    • Korean Journal of Radiology
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    • v.22 no.12
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    • pp.2026-2033
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    • 2021
  • Objective: The aim of this study was to compare the diagnostic performances of digital tomosynthesis (DTS) and conventional radiography in detecting osteonecrosis of the femoral head (ONFH) using computed tomography (CT), as the reference standard and evaluate the diagnostic reproducibility of DTS. Materials and Methods: Forty-five patients (24 male and 21 female; age range, 25-77 years) with clinically suspected ONFH underwent anteroposterior radiography, DTS, and CT. Two musculoskeletal radiologists independently evaluated the presence and type of ONFH. The diagnostic performance of radiography and DTS in detecting the presence of ONFH and determining the types of ONFH were evaluated. The interobserver and intraobserver reliabilities of each imaging modality were analyzed using Cohen's kappa. Results: DTS had higher sensitivity (89.4%-100% vs. 74.5%-76.6%) and specificity (97.3%-100% vs. 78.4%-83.8%) for ONFH detection than radiography. DTS showed higher performance than radiography in identifying the subtypes of ONFH with statistical significance in one reader (type 1, 100% vs. 30.8%, p = 0.004; type II, 97.1% vs. 73.5%, p = 0.008). The interobserver agreement was excellent for DTS and moderate for radiography (kappa of 0.86 vs. 0.57, respectively). The intraobserver agreement for DTS was higher than that of radiography (kappa of 0.96 vs. 0.69, respectively). Conclusion: DTS showed higher diagnostic performance and reproducibility than radiography in detecting ONFH. DTS may be used as a first-line diagnostic modality instead of radiography for patients suspected of having ONFH.

Estimation of Mechanical Properties of Sand Asphalt Concrete based on Physical Properties of Binder (결합재의 물리적 성질을 이용한 샌드아스팔트 혼합물의 강도특성 추정)

  • Kim, Kwang-Woo;Lee, Soon-Jae;Lee, Gi-Ho;Lee, Sung-Hoon;Lee, Byung-Duck
    • International Journal of Highway Engineering
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    • v.4 no.1 s.11
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    • pp.149-159
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    • 2002
  • This study was performed to estimate the high-speed direct tensile strength(DTS1), low-speed direct tensile strength(DTS2) , indirect tensile strength(ITS) resilient modulus(MR) and stiffness index(SI) of sand asphalt mixture based on the absolute viscosity, kinematic viscosity, penetration, softening point and PG grade of binder. DTS2 showed higher correlation with the physical properties than other properties of mixture, and the next was DTS1, ITS, SI and MR in order. Among binder properties, PG grade showed the highest relation with DTS2. Therefore. it was found that the high DTS mixture could be made when the binder with a high PG grade was used. However, since the individual physical property showed a relatively low correlation, various properties were used together in regression analysis. The estimation models of DTS and ITS were over 0.99, respectively. R2 of MR and SI estimation models were over 0.91 and 0.93, respectively. It was concluded that mechanical properties could be estimated with a high coefficient of determination from those physical properties.

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Study on the Development of Optical Sensor Linear Fire Detection System Using Raman Scattering (라만산란을 이용한 광센서 선형 화재감지시스템 개발에 관한 연구)

  • Lee, Gun-Ho;Lim, Woo-Sub;Kim, Si-Kuk
    • Fire Science and Engineering
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    • v.30 no.4
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    • pp.27-38
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    • 2016
  • The paper reports the development of a distributed temperature sensing (DTS) system, which is a fire detection system using optical sensor linear detectors that depends on foreign and domestic technologies. This study accordingly analyzed the electrical signal patterns of Raman scattering light mainly used for temperature sensing among back-scattered light generated in optical fiber by using an oscilloscope. Through the measurement results, it could be verified that the Stokes signal patterns had little change by the temperature increase, but the temperature-sensitive anti-Stokes patterns had relative increase of the changes. This study developed a K-DTS system, which is an optical sensor linear fire detection system composed of an optical repeater and a receiver that can detect fires using Raman scattering light. It could be verified that the developed K-DTS system satisfied the type approval standards through the sensitivity tests using the rate of rise type and fixed temperature type sensitivity testers. In addition, performance experiments have been performed for performance evaluation of the K-DTS system developed in comparison with S-DTS system which has been imported from abroad and widely used in Korea. It can be confirmed from the results of the performance experiments using model tunnels that comparable performances can be obtained in fire detection locations and the measurements of fire temperatures.

DTS-based Temperature Monitoring and Analysis of Battery Cell Deterioration Characteristics by Temperature Condition (DTS 기반 온도 감시 및 온도 조건에서의 배터리 셀 열화 특성 분석)

  • SoonJong, Kwon;Soo-Yeon, Kim;Jin, Hwang;Sang-Kyun, Woo;Bong-Suck, Kim
    • KEPCO Journal on Electric Power and Energy
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    • v.8 no.2
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    • pp.143-149
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    • 2022
  • As ESS safety issues increase recently, there is a need to more precisely monitor the temperature of the ESS. In this paper, DTS technology for temperature monitoring of ESS batteries is introduced and the temperature measurement principle is explained. The temperature of the battery module is measured using the DTS system, and the thermal deviation between battery cells inside the battery module is analyzed. In order to analyze how thermal imbalance affects the charging and discharging performance of the battery, an accelerated degradation test was conducted. Cycle life characteristics analysis, battery surface temperature change, and AC impedance characteristics were conducted to analyze how the performance of battery cells differs according to temperature conditions.

Design and Performance Improvement of a Digital Tomosynthesis System for Object-Detector Synchronous Rotation (물체-검출기 동기회전 방식의 X-선 단층영상시스템 설계 및 성능개선에 관한 연구)

  • Kang, Sung-Taek;Cho, Hyung-Suck;Roh, Byung-Ok
    • Journal of Institute of Control, Robotics and Systems
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    • v.5 no.4
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    • pp.471-480
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    • 1999
  • This paper presents design and performance improvement of a new digital tomosynthesis (DTS) system for object-detector synchronous rotation. Firstly, a new DTS system, called OSDR (Object-Detector Synchronous Rotation) is suggested and designed to acquire X-ray digital images. Secondly, the shape distortion of DTS images generated by an image intensifier is modeled. And a new synthesis algorithm, which overcomes the limitations of the existing synthesis algorithm, is suggested to improve the sharpness of the synthesized image. Also an artifact analysis of the DTS system is performed. Thirdly, some performance indices, which evaluate quantitatively performance improvement, are defined. And the experimental verification of the performance improvement is accomplished by the ODSR system newly designed. The advantages of the ODSR system are expressed quantitatively, compared with an existing system.

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Compressed-sensing (CS)-based Image Deblurring Scheme with a Total Variation Regularization Penalty for Improving Image Characteristics in Digital Tomosynthesis (DTS) (디지털 단층합성 X-선 영상의 화질개선을 위한 TV-압축센싱 기반 영상복원기법 연구)

  • Je, Uikyu;Kim, Kyuseok;Cho, Hyosung;Kim, Guna;Park, Soyoung;Lim, Hyunwoo;Park, Chulkyu;Park, Yeonok
    • Progress in Medical Physics
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    • v.27 no.1
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    • pp.1-7
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    • 2016
  • In this work, we considered a compressed-sensing (CS)-based image deblurring scheme with a total-variation (TV) regularization penalty for improving image characteristics in digital tomosynthesis (DTS). We implemented the proposed image deblurring algorithm and performed a systematic simulation to demonstrate its viability. We also performed an experiment by using a table-top setup which consists of an x-ray tube operated at $90kV_p$, 6 mAs and a CMOS-type flat-panel detector having a $198-{\mu}m$ pixel resolution. In the both simulation and experiment, 51 projection images were taken with a tomographic angle range of ${\theta}=60^{\circ}$ and an angle step of ${\Delta}{\theta}=1.2^{\circ}$ and then deblurred by using the proposed deblurring algorithm before performing the common filtered-backprojection (FBP)-based DTS reconstruction. According to our results, the image sharpness of the recovered x-ray images and the reconstructed DTS images were significantly improved and the cross-plane spatial resolution in DTS was also improved by a factor of about 1.4. Thus the proposed deblurring scheme appears to be effective for the blurring problems in both conventional radiography and DTS and is applicable to improve the present image characteristics.

Effect of tannin contents on the physicochemical characteristics of acorn starch (탄닌함량에 따른 도토리전분의 물리화학적 특성)

  • Ahn, Ho-Kyoung;Choi, Hyeong-Taeg;Kim, Byong-Lyoung;Oh, Doo-Hwan
    • Applied Biological Chemistry
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    • v.33 no.4
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    • pp.301-306
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    • 1990
  • The Physical and chemical properties or dry acorn starch(DS), detannined acorn starch (DTS) and defatted and detannined acorn starch(Drn) were investigated. Ail acorn starch sample, observed by a scanning electron microscope, showed a hemispherical shape ud its size was about $5{\sim}10{\mu}m$ in diameter. It had a little change on the pasting temperature of DS, DTS and DFTS but peak viscosity of DTS was somewhat higher than that of n. Flow behavior of gelatinized starch pastes showed a pseudoplastic behavior and flow behavior index was lower than unit. The consistency coefficient showed concentraion and temperature dependency. The activation energies of DS, DTS and DFTS were $2.09{\sim}3.58Kcal/g\;{\cdot}\;mol and time dependent characteristic of acorn starch samples showed thixotrpic behavior.

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Analysis of the Effectiveness of a Problem-based Digital Textbook

  • Park, Chan-Seok;Kim, Mi-Hye;Yoo, Kwan-Hee
    • International Journal of Contents
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    • v.8 no.2
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    • pp.23-27
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    • 2012
  • The successful use of digital textbooks (DTs) in schools requires the development of various teaching and learning methods that are appropriate for DTs. However, recent DT studies have focused mainly on the implementation of DT features and formats. The objective of this study was to investigate a problem-based learning instructional model appropriate to DTs and to present the experimental results using the problem-based DT to demonstrate its educational effectiveness. Two learning-achievements tests were conducted to analyze the learning experience and effectiveness of the problem-based DT after it had been used in a high school for a certain period. The experimental results indicated that the students who used the DT, especially lower-level students, exhibited improved problem-solving ability and demonstrated a better practical understanding of the subject than students who used printed textbooks.

A Development and Performance Assessment of On-Line Monitoring System for Optical Fiber Composite Underground Distribution Network using DTS (DTS를 활용한 광복합 지중 배전계통 실시간 감시시스템 개발 및 성능평가)

  • Cho, Jin-Tae;Kim, Ju-Yong;Lee, Hak-Ju;Cho, Hwi-Chang;Choi, Myeong-Ho
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.25 no.6
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    • pp.115-121
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    • 2011
  • Intelligent distribution equipment is inevitable to realize self-healing which is one of smart grid functions in distribution network. Therefore, most of distribution equipment have been developed with self diagnostic sensors. However, it is not effective to construct on-line monitoring system for underground distribution cable because of high cost and low sensitivity. Recently, optical fiber composite cable is being considered for communication and power delivery in order to cope with increasing communication in distribution network. This paper presents the design and performance assessment results of underground cable on-line monitoring system using DTS(Distributed Temperature Sensing) and optical fiber composite underground cable.