• KIPS Transactions on Software and Data Engineering
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• v.5 no.9
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• pp.425-432
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• 2016

As the importance of information audit is getting bigger, the public corporations invest many expenses at information system audit to build a high quality system. For this purpose, there are much research to proceed an audit effectively. In database audit works, it could audit utilizing a variety of monitoring tools. However, when auditing SQLs which might be affected to database performance, there are several limits related to SQL audit functionality. For this reason, most existing monitoring tools process based on meta information, it is difficult to proceed SQL audit works if there is no meta data or inaccuracy. Also, it can't detect problems by analysis of SQL's syntax structure. In this paper, we design and implement the SQL Inspector using ANTLR which is applied by syntax analysis technique. The overall conclusion is that the implemented SQL Inspector can work effectively much more than eye-checked way. Finally, The SQL inspector which we proposed can apply much more audit rules by compared with other monitoring tools. We expect the higher stability of information system to apply SQL Inspector from development phase to the operation phase.

• Bulletin of the Korean Chemical Society
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• v.31 no.4
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• pp.881-886
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• 2010

A novel Schiff base N-(2,4-dinitro-phenyl)-N'-(1-phenyl-ethylidene)-hydrazine has been synthesized and structurally characterized by X-ray single crystal diffraction, elemental analysis, IR spectra and UV-vis spectrum. The crystal belongs to monoclinic with space group P21/n. The molecules are connected via intermolecular O-$H{\cdots}O$ hydrogen bonds into 1D infinite chains. The crystal structure is consolidated by the intramolecular N-$H{\cdots}O$ hydrogen bonds. weak intermolecular C-$H{\cdots}O$ hydrogen bonds link the molecules into intriguing 3D framework. Furthermore, Density functional theory (DFT) calculations of the structure, stabilities, orbital energies, composition characteristics of some frontier molecular orbitals and Mulliken charge distributions of the title compound were performed by means of Gaussian 03W package and taking B3LYP/6-31G(d) basis set. The time-dependent DFT calculations have been employed to calculate the electronic spectrum of the title compound, and the UV-vis spectra has been discussed on this basis. The results show that DFT method at B3LYP/6-31G(d) level can well reproduce the structure of the title compound.

• International Journal of High-Rise Buildings
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• v.7 no.2
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• pp.145-151
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• 2018

Newly-designed high-rise buildings, both in China and abroad, have demonstrated new innovations from the creative concept to the creative method. from the creative concept to the creative method. At the same time, digital technology has enabled more design freedom in the vertical dimension. "Twisting" has gradually become the morphological choice of many city landmark buildings in recent years. The form seems more likely to be driven by the interaction of aesthetics and structural engineering. Environmental performance is often a secondary consideration; it is typically not simulated until the evaluation phase. Based on the research results of "DigitalFUTURE Shanghai 2017 Workshop - Wind Tunnel Visualization", an approach that can be employed by architects to design environmental-performance buildings during the early stages has been explored. The integration of a dynamic form-finding approach (DFFA) and programming transforms the complex relationship between architecture and environment into a dialogue of computer language and dynamic models. It allows the design to focus on the relationship between morphology and the surrounding environment, and is not limited to the envelope form itself. This new concept of DFFA in this research consists of three elements: 1) architectural form; 2) integration of wind tunnel and dynamic models; and 3) environmental response. The concept of wind tunnel testing integrated with a dynamic model fundamentally abandons the functional definition of the traditional static environment simulation analysis. Instead it is driven by integral environmental performance as the basic starting point of morphological generation.

• BMB Reports
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• v.37 no.4
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• pp.402-407
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• 2004

A human gene T-complex protein 10 like (TCP10L) was cloned in our lab. A previous study showed that it expressed specifically in the liver and testis. A transcription experiment revealed that TCP10L was a transcription factor with transcription inhibition activity. In this study, the human MAD4 was identified to interact with TCP10L by a yeast two-hybrid screen. This finding was confirmed by immunoprecipitation and subcellular localization experiments. As MAD4 is a member of the MAD family, which antagonizes the functions of MYC and promotes cell differentiation, the biological function of the interaction between TCP10L and MAD4 may be to maintain the differentiation state in liver cells. Also, we propose that the up-regulation of Myc is caused by the down-regulation of TCP10L in human hepatocarcinomas.

• BMB Reports
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• v.37 no.4
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• pp.466-473
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• 2004

A new acid deoxyribonuclease (DNase) was purified from the cultured mycelia of Cordyceps sinensis, and designated CSDNase. CSDNase was purified by $(NH_4)_2SO_4$ precipitation, Sephacryl S-100 HR gel filtration, weak anion-exchange HPLC, and gel filtration HPLC. The protein was single-chained, with an apparent molecular mass of ca. 34 kDa, as revealed by SDS-PAGE, and an isoelectric point of 7.05, as estimated by isoelectric focusing. CSDNase acted on both double-stranded (ds) and single- stranded (ss) DNA, but preferentially on dsDNA. The optimum pH of CSDNase was pH 5.5 and its optimum temperature 55. The activity of CSDNase was not dependent on divalent cations, but its enzymic activity was inhibited by high concentration of the cation: $MgCl_2$ above 150 mM, $MnCl_2$ above 200 mM, $ZnCl_2$ above 150 mM, $CaCl_2$ above 200 mM, NaCl above 300 mM, and KCl above 300 mM. CSDNase was found to hydrolyze DNA, and to generate 3-phosphate and 5-OH termini. These results indicate that the nucleolytic properties of CSDNase are essentially the same as those of other well-characterized acid DNases, and that CSDNase is a member of the acid DNase family. To our knowledge, this is the first report of an acid DNase in a fungus.

• BMB Reports
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• v.40 no.1
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• pp.15-21
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• 2007

Breast cancer is the most common malignancy among women, and mutations in the BRCA1 gene produce increased susceptibility to these malignancies in certain families. In this study, the forward 1-13 exons of breast cancer associated gene BRCA1 were cloned from breast cancer cell line ZR-75-30 by RT-PCR method. Sequence analysis showed that nine BRCA1 splice forms were isolated and characterized, compared with wild-type BRCA1 gene, five splice forms of which were novel. These splice isoforms were produced from the molecular mechanism of 5' and 3' alternative splicing. All these splice forms deleting exon 11b and the locations of alternative splicing were focused on two parts:one was exons 2 and 3, and the other was exons 9 and 10. These splice forms accorded with GT-AG rule. Most these BRCA1 splice variants still kept the original reading frame. Western blot analysis indicated that some BRCA1 splice variants were expressed in ZR-75-30 cell line at the protein level. In addition, we confirmed the presence of these new transcripts of BRCA1 gene in MDA-MB-435S, K562, Hela, HLA, HIC, H9, Jurkat and human fetus samples by RT-PCR analysis. These results suggested that breast cancer associated gene BRCA1 may have unexpectedly a large number of splice variants. We hypothesized that alternative splicing of BRCA1 possibly plays a major role in the tumorigenesis of breast and/or ovarian cancer. Thus, the identification of cancer-specific splice forms will provide a novel source for the discovery of diagnostic or prognostic biomarkers and tumor antigens suitable as targets for therapeutic intervention.

• Geomechanics and Engineering
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• v.9 no.5
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• pp.569-583
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• 2015

Two fundamental issues exist in the damage theory of geo-material based on the concept of thermodynamics: existence or nonexistence of the dissipation potential, and whether the dissipation potential could be decoupled into a damage potential and a plastic one or not. Thermodynamics theory of elastoplastic damage assumes the existence of dissipation potential, but the presence of dissipation potential is conditional. Based on the dissipation inequality in accord with the second law of thermodynamics, the sufficient and necessary conditions are given for the existence of the dissipation potential separately in total and incremental forms firstly, and proved strictly in theory. With taking advantage of the basic mechanical properties of geo-materials, the nonexistence of the dissipative potential is verified. The sufficient and necessary conditions are also given and proved for the decoupling of the dissipation potential of geo-materials in total and incremental forms. Similarly, the non-decoupling of the dissipation potential has also been proved, which indicates the dissipation potential of geo-materials in total or incremental forms could not be decoupled into a dissipative potential for plasticity and that for damage respectively. The research results for the fundamental issues in the thermodynamics theory of damage will help establish and improve the theoretic basis of elastoplastic damage constitutive model for geo-materials.

• Steel and Composite Structures
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• v.17 no.6
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• pp.891-906
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• 2014

This study aims to present a three dimensional finite element model to investigate the wave propagation in a concrete filled steel tubular column (CFSC) due to transient impact load. Both the concrete and steel are regarded as linear elastic material. The impact load is simulated by a semi sinusoidal impulse. Besides the CFSC models, a concrete column (CC) model is established for comparing under the same loading condition. The propagation characteristics of the transient waves in CFSC are analyzed in detail. The results show that at the intial stage of the wave propagation, the velocity waves in CFSC are almost the same as those in CC before they arrive at the steel tube. When the waves reach the column side, the velocity responses of CFSC are different from those of CC and the difference is more and more obvious as the waves travel down along the column shaft. The travel distance of the wave front in CFSC is farther than that in CC at the same time. For different wave speeds in steel and concrete material, the wave front in CFSC presents an arch shape, the apex of which locates at the center of the column. Differently, the wave front in CC presents a plane surface. Three dimensional effects on top of CFSC are obvious, therefore, the peak value and arrival time of incident wave crests have great difference at different locations in the radial direction. High-frequency waves on the waveforms are observed. The time difference between incident and reflected wave peaks decreases significantly with r/R when r/R < 0.6, however, it almost keeps constant when $r/R{\geq}0.6$. The time duration between incident and reflected waves calculated by 3D FEM is approximately equal to that calculated by 1D wave theory when r/R is about 2/3.

• Journal of Korean Tunnelling and Underground Space Association
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• v.19 no.2
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• pp.109-120
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• 2017

Groundwater seepage into a tunnel is one of the main causes triggering tunnel collapse and the consequent ground subsidence. Thus, it is important to estimate adequately the groundwater inflow rate and porewater pressure change during tunneling with time elapse. In current practice, Goodman's analytical solution (or image tunnel method) assuming homogeneous ground condition around a tunnel is commonly used for estimating groundwater inflow rate. However, the generally-used analytical solution for estimating groundwater inflow rate does not consider groundwater level drawdown and permeability change with depth, and the inflow rate can be overestimated in design phase. In this study, parametric study was performed in order to investigate the effect of groundwater level drawdown and permeability reduction with depth, and transient flow analysis was carried out for studying the inflow rate change as well as groundwater level and porewater pressure change around a tunnel with time elapse.

• Journal of Digital Convergence
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• v.18 no.7
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• pp.383-387
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• 2020

This paper studies the GUI design of motion-sensing game character selection. The game's GUI plays a role in transferring information in human-computer interaction. The purpose of this game player-oriented GUI design is to optimize the human-computer interaction, make the operation more user-friendly, reduce the user's cognitive burden, and better adapt to the user's operation needs. This paper combines examples to compare and analyze these three games from three aspects: text, color and form. In the existing motion-sensing game games, the character selection GUI has a design feature of high recognition and strong visibility. Finally, suggestions for GUI design of motion-sensing game games are given. It is hoped that in the future, reference materials will be provided for the GUI design of experience game character selection.