• Title/Summary/Keyword: ZhangHua

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Weighted Local Naive Bayes Link Prediction

  • Wu, JieHua;Zhang, GuoJi;Ren, YaZhou;Zhang, XiaYan;Yang, Qiao
    • Journal of Information Processing Systems
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    • v.13 no.4
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    • pp.914-927
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    • 2017
  • Weighted network link prediction is a challenge issue in complex network analysis. Unsupervised methods based on local structure are widely used to handle the predictive task. However, the results are still far from satisfied as major literatures neglect two important points: common neighbors produce different influence on potential links; weighted values associated with links in local structure are also different. In this paper, we adapt an effective link prediction model-local naive Bayes model into a weighted scenario to address this issue. Correspondingly, we propose a weighted local naive Bayes (WLNB) probabilistic link prediction framework. The main contribution here is that a weighted cluster coefficient has been incorporated, allowing our model to inference the weighted contribution in the predicting stage. In addition, WLNB can extensively be applied to several classic similarity metrics. We evaluate WLNB on different kinds of real-world weighted datasets. Experimental results show that our proposed approach performs better (by AUC and Prec) than several alternative methods for link prediction in weighted complex networks.

Deformation analyses during subway shield excavation considering stiffness influences of underground structures

  • Zhang, Zhi-guo;Zhao, Qi-hua;Zhang, Meng-xi
    • Geomechanics and Engineering
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    • v.11 no.1
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    • pp.117-139
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    • 2016
  • Previous studies for soil movements induced by tunneling have primarily focused on the free soil displacements. However, the stiffness of existing structures is expected to alter tunneling-induced ground movements, the sheltering influences for underground structures should be included. Furthermore, minimal attention has been given to the settings for the shield machine's operation parameters during the process of tunnels crossing above and below existing tunnels. Based on the Shanghai railway project, the soil movements induced by an earth pressure balance (EPB) shield considering the sheltering effects of existing tunnels are presented by the simplified theoretical method, the three-dimensional finite element (3D FE) simulation method, and the in-situ monitoring method. The deformation prediction of existing tunnels during complex traversing process is also presented. In addition, the deformation controlling safety measurements are carried out simultaneously to obtain the settings for the shield propulsion parameters, including earth pressure for cutting open, synchronized grouting, propulsion speed, and cutter head torque. It appears that the sheltering effects of underground structures have a great influence on ground movements caused by tunneling. The error obtained by the previous simplified methods based on the free soil displacements cannot be dismissed when encountering many existing structures.

Enhancing Astaxanthin Accumulation in Haematococcus pluvialis by Coupled Light Intensity and Nitrogen Starvation in Column Photobioreactors

  • Zhang, Wen-wen;Zhou, Xue-fei;Zhang, Ya-lei;Cheng, Peng-fei;Ma, Rui;Cheng, Wen-long;Chu, Hua-qiang
    • Journal of Microbiology and Biotechnology
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    • v.28 no.12
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    • pp.2019-2028
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    • 2018
  • Natural astaxanthin mainly derives from a microalgae producer, Haematococcus pluvialis. The induction of nitrogen starvation and high light intensity is particularly significant for boosting astaxanthin production. However, the different responses to light intensity and nitrogen starvation needed to be analyzed for biomass growth and astaxanthin accumulation. The results showed that the highest level of astaxanthin production was achieved in nitrogen starvation, and was 1.64 times higher than the control group at 11 days. With regard to the optimization of light intensity utilization, it was at $200{\mu}mo/m^2/s$ under nitrogen starvation that the highest astaxanthin productivity per light intensity was achieved. In addition, both high light intensity and a nitrogen source had significant effects on multiple indicators. For example, high light intensity had a greater significant effect than a nitrogen source on biomass dry weight, astaxanthin yield and astaxanthin productivity; in contrast, nitrogen starvation was more beneficial for enhancing astaxanthin content per dry weight biomass. The data indicate that high light intensity synergizes with nitrogen starvation to stimulate the biosynthesis of astaxanthin.

Selaginella austrotibetica (Selaginellaceae), a new spikemoss from Xizang, China

  • Meng-Hua Zhang;Jie Yang;Aleksandr Petrovich Shalimov;Jong-Soo Kang;Xian-Chun Zhang
    • Journal of Species Research
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    • v.13 no.1
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    • pp.1-9
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    • 2024
  • Selaginella austrotibetica, a new spikemoss species from China, is described. The species is epipetric and was found on a moss-covered rocky cliff by a riverbank. Morphologically, it is unlike any anisosporophyllous species in the genus Selaginella. However, it resembles species of the S. sanguinolenta group, especially similar to S. sajanensis in gross morphology, except for the characters of strobilus. The molecular phylogenetic analysis clearly showed that S. austrotibetica was nested within the anisosporophyllous species clade, forming a sister relationship with the clade of S. vaginata and S. xipholepis, and distinct from the S. sanguinolenta group, including S. sajanensis. Although S. austrotibetica is sister to the clade of S. vaginata and S. xipholepis, the species can be clearly distinguished by its sparse leaves on branches, dorsal leaves that are broad-ovate, base obtuse to rounded, margin denticulate or very shortly sparsely ciliolate, and leaves that are slightly thick and shiny. Therefore, we described Selaginella austrotibetica as a new species and discuss its phylogenetic relationships within the genus Selaginella.

Genetic Diversity of a Chinese Native Chicken Breed, Bian Chicken, Based on Twenty-nine Microsatellite Markers

  • Ding, Fu-Xiang;Zhang, Gen-Xi;Wang, Jin-Yu;Li, Yuan;Zhang, Li-Jun;Wei, Yue;Wang, Hui-Hua;Zhang, Li;Hou, Qi-Rui
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.2
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    • pp.154-161
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    • 2010
  • The level of genetic differentiation and genetic structure in a Chinese native chicken breed, Bian chicken, and two controlled chicken populations (Jinghai chicken and Youxi chicken in China) were analysed based on 29 microsatellite markers. A total of 166 distinct alleles were observed across the 3 breeds, and 32 of these alleles (19.3%) were unique to only 1 breed. Bian chicken carried the largest number of private alleles at 15 (46.9%), followed by the Jinghai chicken with 12 private alleles (37.5%). The average polymorphism information content (0.5168) and the average expected heterozygote frequency (0.5750) of the Bian chicken were the highest, and those of the Jinghai chicken were 0.4915 and 0.5505, respectively, which were the lowest. Among 29 microsatellite loci, there were 15 highly informative loci in Bian chicken, and the other 14 were reasonably informative loci. The highly informative loci in Jinghai chicken and Youxi chicken were 17 and 14 respectively. Significant deviations from the Hardy-Weinberg equilibrium were observed at several locus-breed combinations, showing a deficit of heterozygotes in many cases. As a whole, genetic differentiation among the breeds estimated by the fixation index (Fst) were at 6.7% (p<0.001). The heterozygote deficit within population (Fis) was 22.2% (p<0.001), with the highest (0.249) in Bian chicken and lowest (0.159) in Youxi chicken. These results serve as an initial step in the plan for genetic characterization and conservation of the Chinese chicken genetic resource of Bian, as well as Jinghai and Youxi chickens.

MSP58 Knockdown Inhibits the Proliferation of Esophageal Squamous Cell Carcinoma in Vitro and in Vivo

  • Xu, Chun-Sheng;Zheng, Jian-Yong;Zhang, Hai-Long;Zhao, Hua-Dong;Zhang, Jing;Wu, Guo-Qiang;Wu, Lin;Wang, Qing;Wang, Wei-Zhong;Zhang, Jian
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3233-3238
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    • 2012
  • Esophageal carcinoma (EC) is one of the most aggressive cancers with a poor prognosis. Understanding the molecular mechanisms underlying esophageal cancer progression is a high priority for improved EC diagnosis and prognosis. Recently, MSP58 was shown to behave as an oncogene in colorectal carcinomas and gliomas. However, little is known about its function in esophageal carcinomas. We therefore examined the effects of MSP58 knockdown on the growth of esophageal squamous cell carcinoma (ESCC) cells in vitro and in vivo in order to gain a better understanding of its potential as a tumor therapeutic target. We employed lentiviral-mediated small hairpin RNA (shRNA) to knock down the expression of MSP58 in the ESCC cell lines Eca-109 and EC9706 and demonstrated inhibition of ESCC cell proliferation and colony formation in vitro. Furthermore, flow cytometry and western blot analyses revealed that MSP58 depletion induced cell cycle arrest by regulating the expression of P21, CDK4 and cyclin D1. Notably, the downregulation of MSP58 significantly inhibited the growth of ESCC xenografts in nude mice. Our results suggest that MSP58 may play an important role in ESCC progression.

Effect of Ginseng Total Saponin on Bovine Adrenal Tyrosine Hydroxylase

  • Kim, Hack-Seang;Zhang, Yong-He;Fang, Lian-Hua;Lee, Myung-Koo
    • Archives of Pharmacal Research
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    • v.21 no.6
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    • pp.782-784
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    • 1998
  • Ginseng total saponin (GTS) can modulate dopaminergic activity at both presynaptic and postsynaptic dopamine receptors (Kim et al, 1998). The present study investigated t he effect of GTS on the bovine adrenal tyrosine hydroxylase (TH), which catalyze L/tyrosine to DOP. GTS inhibited the bovine adrenal TH by 42.4, 51.5 and 55.3% at concentrations of 40, 80 and 100${\mu}g$/ml, respectively. The IC50 value of GTS was 77.5${\mu}g$/ml. GTS exhibited noncompetitive inhibition with a substrate L-tyrosine. The Ki value was 155${\mu}g$/ml.

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Interaction of internal forces of interior beam-column joints of reinforced concrete frames under seismic action

  • Zhou, Hua;Zhang, Jiangli
    • Structural Engineering and Mechanics
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    • v.52 no.2
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    • pp.427-443
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    • 2014
  • This paper presents detailed analysis of the internal forces of interior beam-column joints of reinforced concrete (RC) frames under seismic action, identifies critical joint sections, proposes consistent definitions of average joint shear stress and average joint shear strain, derives formulas for calculating average joint shear and joint torque, and reports simplified analysis of the effects of joint shear and torque on the flexural strengths of critical joint sections. Numerical results of internal joint forces and flexural strengths of critical joint sections are presented for a pair of concentric and eccentric interior connections extracted from a seismically designed RC frame. The results indicate that effects of joint shear and torque may reduce the column-to-beam flexural strength ratios to below unity and lead to "joint-yielding mechanism" for seismically designed interior connections. The information presented in this paper aims to provide some new insight into the seismic behavior of interior beam-column joints and form a preliminary basis for analyzing the complicated interaction of internal joint forces.

Recovery Voltage Measurements of Oil-immersed Transformer

  • Li, Ming-Hua;Dong, Ming;Qu, Yan-Ming;Yan, Zhang
    • Transactions on Electrical and Electronic Materials
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    • v.7 no.5
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    • pp.230-234
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    • 2006
  • One of the methods currently being investigated as a possible non-intrusive diagnostic tool for condition monitoring of power transformer and cable is the recovery voltage measurement, which will be improving the ability to detect the content of water concentration and the ageing process in the insulation system and may thus be an indicator of insulation quality and its ageing status. The polarization phenomenon was studied using RVM with oil-paper samples. In order to interpret its mechanism, the Extended Debye model was introduced. With different circuit parameters, various simulation results were gotten. Furthermore, with the test samples of different ageing condition, measurements are accomplished in the lab. On the basis of this experiment as well as theoretical analysis, correlations between polarizations and ageing were analyzed.

A Study on deviation reduction of indoor location determination using fingerprint method (Fingerprint 방법을 활용한 실내 위치 결정의 산포 감소 방안에 관한 연구)

  • Kwon, Dae-Woo;Lee, Doo-Yong;Piao, Xue-Hua;Song, Young-Keun;Jang, Jung-Hwan;Zhang, Jing-Lun;Lee, Chang-Ho
    • Proceedings of the Safety Management and Science Conference
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    • 2010.11a
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    • pp.331-335
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    • 2010
  • 본 논문에서는 위치기반서비스의 핵심기능을 담당하는 측위기술 중 주변의 다양한 잡음환경에서도 다른 측위기술에 비해 비교적 측위오차를 줄일 수 있는 Fingerprint 기법을 적용하여 객체의 위치를 결정하는 방법을 제시하였다. 특히, Fingerprint 기법을 활용함에 있어서 결정적 측위방법이 아닌 확률적 측위방법을 사용하였고, 기존의 연구들에서 제시된 확률적 측위방법에서 인접 RP(Reference Point)들과의 영향성까지 고려한 측위방법을 제시한 것이 본 연구의 특징이다. 비주얼베이직 6.0으로 측위 프로그램을 구현하였고, 실내 외 연속측위의 선행연구로서 실내 측위 테스트를 통해 기존의 결정적 방법, 확률적 방법, 그리고 본 연구에서 제안하는 방법의 측위 정확성을 평가하였다. 테스트 결과, 결정적 측위 방법 및 기존의 확률적 측위방법과 비교하여 각각 평균 15%와 7% 측위 오차가 감소하였다.

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