• Journal of Plant Biotechnology
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• 제50권
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• pp.97-107
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• 2023

Malaria remains to be one of the most severe global public health concerns. Traditionally, Aspilia Africana and Warburgia ugandensis have been used to treat malaria in several African countries for millennia. In the current study, A. africana calli (AaC), A. africana in vitro roots (AaIR), A. africana wild leaf (AaWL), and W. ugandensis stem bark (WuSB) were dried and pulverized. Fourier transform near-infrared spectroscopy was used to analyze the powdered samples, while 80% ethanolic extracts of each sample were assayed for antiplasmodial activity (against Plasmodium falciparum strains DD2 (chloroquine-resistant) and 3D7 (chloroquine-sensitive)) and cytotoxicity. WuSB showed the highest antiplasmodial activity (IC₅₀ = 1.57 ± 0.210 ㎍/ml and 8.92 ± 0.365 ㎍/ml against P. falciparum 3D7 and DD2, respectively) and selectivity indices (43.90 ± 7.914 and 7.543 ± 0.051 for P. falciparum 3D7 and DD2, respectively). The highest total polyphenolic contents (total phenolic and flavonoid contents of 367.9 ± 3.55 mg GAE/g and 203.9 ± 1.43 mg RUE/g, respectively) were recorded for WuSB and the lowest were recorded for AaC. The antiplasmodial activities of the tested plant tissues correlated positively with total polyphenolic content. The high selectivity indices of WuSB justify its traditional applications in treating malaria and present it as a good candidate for discovering new antimalarial compounds. We recommend elicitation treatment for AaIR, which showed moderate antiplasmodial activity against P. falciparum DD2, to increase its secondary metabolite production for optimal antimalarial activity.

• Toxicological Research
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• 제13권1_2호
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• pp.39-48
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• 1997

Cyclophosphamide(25, 50 or 100 mg/kg), orally administered to male Sprague-Dawley rats, caused a time- and dose-dependent thymic atrophy. In the light microscopic examination of the atrophic thymus, thymocytes with condensed or fragmented nucleus were multifocally observed in the cortical region, started to increase 8 hr after CPA treatment and reached to the maximal level at 16 hr, although such cells were not seen after 48 hr when the severe depletion of thymocytes were marked. In agarose gel electrophoresis to analyze the DNA changes, DNA extracted from atrophic thymus showed a oligonucleosomal laddering at the corresponding time to morphological changes. In an additional supportive experiment, thymocytes showing morphological changes, nuclear condensation or apoptotic body, exhibited a positive reaction to immunoperoxidase staining using in situ apoptosis detection kit. Separately, agarose gel electrophoresis of DNA from bone .marrow cells was performed to investigate the involvement of bone marrow cells in the process of thymocyte apoptosis. Although DNA laddering was slightly increased 2 and 4 hr after treatment, no clear correlation was inferred. Taken togather, it is concluded that thymocytes showing morphological changes in thymic atrophy induced by cyclophosphamide administration represent an apoptosis having biochemical nature of programmed cell death.

• 한국전문물리치료학회지
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• 제20권2호
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• pp.38-45
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• 2013

This study was conducted in order to examine whether abdominal draw-in maneuver (ADIM) with isometric shoulder flexion, extension, adduction, and abduction selectively contracted deep abdominal muscles. This study's subjects were 13 males 17 females. In order to evaluate the comparison of effects of ADIM and ADIM with isometric shoulder flexion, extension, adduction and abduction, measurements were made on transverse abdominis (TrA), internal oblique (IO), and external oblique (EO) using a real-time ultrasonic diagnostic imaging system. Each position was repetitively measured three times with a real-time ultrasonic diagnostic imaging system and their mean values were used for analysis. The ADIM with isometric shoulder flexion, extension, adduction and abduction significantly increased the thickness of TrA relative to the ADIM only (p<.05). The ADIM with isometric shoulder abduction significantly increased the thickness of IO compared to the ADIM only (p<.05). The ADIM with isometric shoulder extension and abduction significantly decreased the thickness of EO compared to the ADIM only and the ADIM with isometric shoulder extension significantly decreased the thickness of EO relative to the ADIM with isometric shoulder adduction (p<.05). ADIM with isometric shoulder abduction is an effective method to selectively strengthen deep abdominal muscles and therefore may be employed as an intervention for trunk stabilization.

• 한국전문물리치료학회지
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• 제20권2호
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• pp.52-59
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• 2013

The purpose of this study was to determine the reliability and validity of the postural balance program which uses the movement accelerating field principles of posture balance training and evaluation equipment and smartphone movement accelerometer program (SMAP) in healthy young adults. A total of 34 people were appointed as the subject among the healthy young adults. By using Biodex stability system (BSS) and SMAP on the subject, the posture balance capability was evaluated. For the test-retest reliability, SMAP showed the intra-class correlation (ICC: .62~.91) and standard error measurement (SEM: .01~.08). BSS showed the moderate to high reliability of ICC (.88~.93) and SEM (.02~.20). In the reliability of inter-rater, ICC (.59~.73) as to SMAP, showed the reliability of moderate in eyes open stability all (EOSA), eyes open stability anterior posterior (EOSAP), eyes open stability medial lateral (EOSML) and eyes open dinamic all (EODA), eyes open danamic anterior posterior (EODAP), and eyes open danamic medial lateral (EODML). However, ICC showed reliability which was as low as .59 less than in other movements. In addition, BSS showed the reliability of high as ICC (.70~.75). It showed reliability which was as low as ICC (.59 less than) in other movements. In correlation to the balance by attitudes between SMAP and BSS, EOSML (r=.62), EODA (r=.75), EODML (r=.72), ECDAP (r=.64), and ECDML (r=.69) shown differ significantly (p<.05). However, the correlation noted in other movements did not differ significantly. Therefore, SMAP and BSS can be usefully used in the posture balance assessment of the static and dynamic condition with eyes opened and closed.

• 보건교육건강증진학회지
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• 제33권2호
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• pp.57-66
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• 2016

Objectives: This study investigated the relationship between smoking status and depressive symptoms among Korean adults. Methods: We used the data of 17,871 adults aged 19 years or older from the fifth Korea National Health and Nutrition Examination Survey(2010-2012). The subjects were classified as nonsmokers, former smokers, and current smokers by gender. Logistic regression analysis was used to calculate the odds ratios(ORs) and the 95% confidence intervals(CIs) for the effects of smoking status on depressive symptoms, and depression diagnosed by a doctor. Results: Compared to nonsmokers, the ORs of depressive symptoms for current smokers were 1.11(95% CI, 1.11-1.12) among males, and 1.64(95% CI, 1.63-1.64) among females. Compared to former smokers, the ORs of depressive symptoms for current smokers were 1.05(95% CI, 1.05-1.05) among males, and 1.89(95% CI 1.88-1.90) among females. Compared to nonsmokers, the ORs of depression for current smokers were 0.94(95% CI, 0.94-0.95) among males, and 1.40(95% CI, 1.39-1.41) among females. Compared to former smokers, the ORs of depression for current smokers were 1.09(95% CI, 1.09-1.10) among males, and 0.99(95% CI, 0.99-1.00) among females. Conclusions: Smoking is associated with depressive symptoms among Korean adults. Therefore, it is necessary to consider depressive symptoms with the management of tobacco control policies.

• 한국주거학회논문집
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• 제20권5호
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• pp.31-39
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• 2009

The purpose of this study was to find out the residents' consciousness of the unit plan on condominium apartment and to contribute to develop a condominium apartment unit plan in Daejeon City. This research was performed by a questionnaire survey method, 464 data was collected from apartment residents lived in about $85\;m^2$ unit with 3 rooms and the apartments was limited to the complexes within 1-4 years of the length of building at Yuseong-gu and Seo-gu. By analyzing those data, findings are as follows: 1) Residents thought living room, kitchen and bathroom were importment space in a unit plan. They needed a storage function in an entrance and a intermediate room, and Anbang(mater bedroom) so did. 2) L-DK plan type was very popular and the type of front DK with L on the floor plan was preferred. This was unique results. 3) Sub-kitchen was needed for a refrigerator of Kimchi, the location of it was related to a main kitchen and a utility. the third room was needed for library, home office and storage space. 3) Bath-tub in An-bang and showe-booth in public bathroom was preferred. This was same to the popular trend of Korean condominium apartment. 4) The enlargment remodeling of balcony was showed livingroom balcony or personal bedrooms at the time of occupancy. They needed the balcony near a kitchen or an utility to equip a storage facility. Additionally, residents were preferred to their taste rather than a choice of interior concept package services.

• 한국응용곤충학회지
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• 제41권4호
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• pp.255-261
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• 2002

토마토녹응애(개칭)에 대해 주사전자현미경 관찰, 국내 분포, 기주식물, 온도에 따른 발육상, 약제 방제법에 관하여 연구하였다. 토마토녹응애는 2쌍의 다리를 가진 길이 $134.9\mu\textrm{m}$의 미소동물로 feathered claw는 4줄이었다. 피해증상으로, 피해엽은 적갈색으로 변하고 줄기에는 털이 없어지고 광택이 나거나 표면이 그물형으로 갈라지며, 새순은 시들거나 위축된다. 과일은 과경 부근에 그을음이나 녹이 긴 것 같이 되고, 그물형으로 갈라진다. 충남의 부여와 유성, 강원도 평창, 경북의 칠곡, 구룡포의 유리온실에서 발견되었으며, 한국에서 기주로는 메꽃, 까마중, 가지, 꽈리, 나팔꽃, 페투니아, 감자, 고추, 담배, 토마토 등이 확인되었다. 이 응애는 $15-30^{\circ}C$에서 발육이 가능하였고, 한 세대는 6-11일로 높은 온도일수록 발육기간이 짧아지는 경향이었으며, 암컷이 수컷보다 수명이 길었는데, 25-28$^{\circ}C$에서 12일로 가장 수명이 길었다. 살비제 중에서 fenazaquin과 cypermethrin의 효과가 가장 좋았다.

• Journal of Plant Biotechnology
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• 제48권2호
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• pp.115-122
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• 2021

Aspilia africana (Pers) C.D.Adams, a plant used for centuries in many African countries to treat diseases such as osteoporosis, malaria, tuberculosis, and diabetes, is of great pharmaceutical interest, yet there is limited scientific literature on its germination and growth. This research paper describes the effects of different commercial soils on the germination, growth, and chlorophyll content of A. africana. The germination parameters assessed included final germination percentage (FGP), mean germination time (MGT), and germination index (GI). Shoot length, leaf number, and fresh and dry weights were some of the parameters used to assess A. africana growth. The FGP was low and did not vary significantly; the MGT was 7 ~ 10 days; and the GI was significantly higher in PPS soil at 4.61 ± 0.332 days. Aspilia africana plants in HS:PPS soil showed the best overall growth, producing the highest mean leaf number (18.00 ± 1.129), longest mean shoot length (202.43 ± 13.451 mm), and highest mean fresh and dry weights (7.08 ± 1.061 g and 0.629 ± 0.112 g, respectively). The highest chlorophyll content in leaves of A. africana under HS:PPS conditions suggested a higher photosynthetic potential of plants in this soil. The best growth performance of A. africana in the HS:PPS soil could be attributed to a higher amount of certain mineral nutrients such as nitrogen, potassium, and phosphorus in the HS:PPS soil compared to the other soil categories. It is unclear why the FGP of A. africana was low and we recommend an exclusive study to investigate this further.

• 한국학교수학회논문집
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• 제10권2호
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• pp.207-219
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• 2007

수학에서 중요한 부분인 증명을 학생들은 어려워한다. 증명을 테크놀로지를 이용하여 대수적 시각화 자료와 특수화된 시각화 자료를 만들어 지도하였다. 그러나 테크놀로지를 활용한 대수적 시각화 자료의 표현상 오류에 의하여, 학생들이 경험적 인식을 가지지 못하여 경험적 정당화를 하는데 어려움이 있었다. 테크놀로지를 활용한 특수화된 시각화 자료는 고정된 경우에만 성립하기 때문에 수학적 사고의 확장을 제한하였다. 이를 해결하기 위해서 테크놀로지를 활용하여 자체 제작한 중학교 3학년 기하단원의 기하적 시각화 자료와 일반화된 시각화 자료를 통해 학생들에게 경험적 인식을 심어주어 경험적 정당화를 시켰으며, 수학적 사고의 향상을 관찰할 수 있었다.

• 농업과학연구
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• 제38권1호
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• pp.39-44
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• 2011

The changes in major moth populations were monitored by sex pheromone traps in pear orchards at Yuseong-Gu, Daejeon from 2008 to 2010. Among four major moths, Grapholita molesta and Caposina sasakii occurred most frequently. Their occurrences peaked 2 to 3 times during the growing season from May to September. G. molesta was exceptional, occurring until September. For the environmentally-friendly control of these moths, 9 control materials including insect pathogenic bacteria and environmentally-friendly agricultural materials, were examined on the larva of 4 kinds of moth and sprayed on pear leaves in the field. As the generalized results of bioassay, Bacillus thuringiensis subsp. kurstaki and Sophora flavescens extract were shown to have better control effects than any other control material.