• 제목/요약/키워드: Young-Jung Kim

검색결과 23,201건 처리시간 0.07초

Reagentselective reduction of 25(R)-1,4,6-spirostatrien-3-one

  • Ma, Eun-Sook;Kim, Hak-Soon;Kim, Eun-Jung;Jung, Won-Young;Choi, Tae-Young
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.234.1-234.1
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    • 2003
  • Spicatoside A and spicatoside B were isolated from Liriopis tuber. Spicatoside A has anticancer activity and it is composed of 1 ${\beta}$-hydroxy diosgenin and trisaccharides. Spicatoside B has the preventive effect of diabetes mellitus and also has 1 ${\beta}$-hydroxy derivatives, which is clevaged the ether linkage of F ring of diosgenin. Therefore, selective synthesis of 1 ${\beta}$-hydroxydiosgenin is required. (omitted)

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Genotoxicity Study of sophoricoside in bacterial and mammalian cells system

  • Yun, Hye-Jung;Kim, Youn-Jung;Kim, Eun-Young;Kim, Young-Soo;Kim, Mi-Kyung;Lee, Seung-Ho;Jung, Sang-Hun;Ryu, Jae-Chun
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.177.1-177.1
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    • 2003
  • Sophoricoside was isolated as the inhibitor of IL -5 bioactivity from Sophora japonica (Leguminosae). It has been reported to have an anti-inflammatory effect on rat paw edema model. To develope as an anti-allergic drug, genotoxicity of sophoricoside was investigated in bacterial and mammalian cell system such as Ames bacterial test and mouse lymphoma tk gene assay (MOLY). (omitted)

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Genotoxicity Study of sophoricoside derivatives in mammalian cells system

  • Yun, Hye-Jung;Kim, Youn-Jung;Kim, Eun-Young;Kim, Young-Soo;Kim, Mi-Kyung;Lee, Seung-Ho;Jung, Sang-Hun;Ryu, Jae-Chun
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.178.2-178.2
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    • 2003
  • To develope the novel anti-allergic drug, many sophoricoside derivatives were synthesized. Among these derivatives, JSH-II-3, JSH-Ⅵ-3, JSH-Ⅶ-3, and JSH-Ⅷ-3 were selected and subjected to high throughput toxicity screening (HTTS) because they revealed strong IL-5 inhibitory activity and limitation of Quantity. Mouse lymphoma thymidine kinase ($tk^{+/-}$) gene assay(MOLY) and single cell gel electrophoresis (Comet) assay in mammalian cells were used as HTTS tool in our laboratory. (omitted)

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등설망둑 Pariolossus dotui Tomiyama의 난발생

  • 윤영석;노섬;최영웅;박정호;정민민;나오수;이영돈
    • 한국어업기술학회:학술대회논문집
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    • 한국어업기술학회 2002년도 추계 수산관련학회 공동학술대회발표요지집
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    • pp.291-292
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    • 2002
  • 등설망둑, Pariolossus dotui Tomiyama은 농어목(Order Perciformes), 망둑어아목(Suborder Gobioidei), 청황문절과(Family Microdesmidae) 속하는 소형어류로 주로 해안의 기수역에 집단으로 유영생활을 하며(Kim & Han, 1993) 우리나라 남해안과 제주도 그리고 서태평양과 인도양의 따뜻한 온대에서 열대해역까지 분포한다.(Rennis and Hoese, 1985) (중략)

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