• Archives of Pharmacal Research
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• v.27 no.2
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• pp.194-198
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• 2004

Reactive oxygen species (ROS) play an important role in the pathogenesis of many human degenerative diseases such as cancer, aging, arteriosclerosis, and rheumatism. Much attention has been focused on the development of safe and effective antioxidants. To discover sources of antioxidative activity in marine algae, extracts from 17 kinds of seaweed were screened for their inhibitory effect on total ROS generation in kidney homogenate using 2',7'-dichlorofluorescein diacetate (DCFH-DA). ROS inhibition was seen in three species: UIva pertusa, Symphyocladia latiuscula, and Ecklonia stolonifera. At a final concentration of 25 $\mu\textrm{g}$/mL, U. pertusa inhibited 85.65$\pm$20.28％ of total ROS generation, S. latiscula caused 50.63$\pm$0.09％ inhibitory, and the Ecklonia species was 44.30$\pm$7.33％ inhibition. E. stolonifera OKAMURA (Lam-inariaceae), which belongs to the brown algae, has been further investigated because it is commonly used as a foodstuff in Korea. Five compounds, phloroglucinol (1), eckstolonol (2), eckol (3), phlorofucofuroeckol A (4), and dieckol (5), isolated from the ethyl acetate soluble fraction of the methanolic extrclct of E. stolonifera inhibited total ROS generation.

• Proceedings of the SAREK Conference
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• 2008.06a
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• pp.782-787
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• 2008

The Kalina cycle simulation study was carried out for a preliminary design of a geothermal power generation system. The Kalina cycle system can be used for the utilization of a low-temperature heat sources such as geothermal and industrial waste heat that are not hot enough to produce steam. The sea/river water can be considered as a cooling media. A steady-state simulation model was developed to analyze and optimize its performance. The model contains a turbine, a pump, an expansion valve and heat exchangers. The turbine and pump were modelled by an isentropic efficiency, while a condenser, an evaporator and a regenerative heat exchanger were modeled by UA-LMTD method with a counter-flow assumption. The simulation results show that the power generation efficiency over 10% is expected when a heat source and sink inlet temperatures are $100^{\circ}C$ and $10^{\circ}C$ respectively.

• Nuclear Engineering and Technology
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• v.37 no.3
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• pp.279-286
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• 2005

A prototype of a relativistic proton generation system, based on laser-induced plasma interaction, has been designed and fabricated. The system is composed of three major parts: a fs TW laser; a target chamber, including targets and controls; and a diagnostic system for charged particles and lasers. An Offner-type pulse stretcher for chirped pulse amplification (CPA) and eight pass pre-amplifier are installed. The main amplifier will be integrated with a new pumping laser. The design values of the laser at the first stage are 1 TW in power and 50 fs in pulse duration. We expect to generate protons with their maximum energy of approximately 3 MeV and the flux of at least $10^6$ per pulse using a 10 $\mu$m Al target. A prototype target chamber with eight 8-inch flanges, including target mounts, has been designed and fabricated. For laser diagnostics, an adaptive optics based on the Shack-Hartmann type, beam monitoring, and alignment system are all under development. For a charged particle, CR-39 detectors, a Thomson parabola spectrometer, and Si charged-particle detectors will be used for the density profile and energy spectrum. In this paper, we present the preliminary design for laser-induced proton generation. We also present plans for future work, as well as theoretical simulations.

• Journal of Microbiology and Biotechnology
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• v.22 no.2
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• pp.270-273
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• 2012

These studies were conducted to determine the effects of various concentrations of ammonium and nitrate on current generation using dual-cathode microbial fuel cells (MFCs). Current generation was not affected by ammonium up to $51.8{\pm}0.0$ mg/l, whereas $103.5{\pm}0.0$ mg/l ammonium chloride reduced the current slightly. On the other hand, when $60.0{\pm}0.0$ and $123.3{\pm}0.1$ mg/l nitrate were supplied, the current was decreased from $10.23{\pm}0.07$ mA to $3.20{\pm}0.24$ and $0.20{\pm}0.01$ mA, respectively. Nitrate did not seem to serve as a fuel for current generation in these studies. At this time, COD and nitrate removal were increased except at $123{\pm}0.1$ mg ${NO_3}^-/l$. These results show that proper management of ammonium and nitrate is very important for increasing the current in a microbial fuel cell.

• The Korean Journal of Physiology and Pharmacology
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• v.11 no.1
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• pp.31-36
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• 2007

To elucidate a potential molecular link between diabetes and atherosclerosis, we investigated the role of Janus tyrosine kinase(JAK) for NAD(P)H oxidase-derived superoxide generation in the enhanced proliferative capacity of vascular smooth muscle cells(VSMC) of Otsuka Long-Evans Tokushima Fatty(OLETF) rat, an animal model of type 2 diabetes. An enhanced proliferative response to 10% fetal bovine serum(FBS) and superoxide generation with an increased NAD(P)H oxidase activity were observed in diabetic(OLETF) VSMC. Both the enhanced proliferation and superoxide generation in diabetic VSMC were significantly attenuated by AG490, JAK2 inhibitor, and PP2, Src kinase inhibitor. Tyrosine phosphorylation of proteins in diabetic VSMC, especially JAK2, was increased compared to control VSMC. Furthermore, the enhanced NAD(P)H oxidase activity in diabetic VSMC was significantly attenuated by AG490 in a dose-dependent manner. Together, these results indicate that the signal pathway which leads to diabetes-associated activation of Src kinase/JAK is critically involved in the diabetic VSMC proliferation through NAD(P)H oxidase activation and superoxide generation.

• Journal of Hydrogen and New Energy
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• v.32 no.5
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• pp.324-330
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• 2021

In recent years, polymer electrolyte membrane fuel cell (PEMFC) based cogeneration system has received more and more attention from energy researchers because beside electricity, the system also meets the residential thermal demand. However, the low-quality heat exited from PEMFC should be increased temperature before direct use or storage. This study proposes a method to utilize the heat exhausted from a 10 kW PEMFC by coupling a heat pump. Two different configuration using heat pump and a reference layout with heater are analyzed in term of thermal and total efficiency. The system coefficient of performance (COP) increases from 0.87 in layout with heaters to 1.26 and 1.29 in configuration with heat pump and cascade heat pump, respectively. Lastly, based on system performance result, another study in economics point of view is proposed.

• Journal of Hydrogen and New Energy
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• v.32 no.5
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• pp.331-339
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• 2021

This study presents a novel way to enhance uniformity of the gas flow inside the solid oxide fuel cell (SOFC), which is critically important to fuel cell performance, by using dimples. A pattern of dimple, which works as a flow distributor/collector, is designed at the inlet and outlet section of a straight channel gas separator. Size of the dimples and the gap between them were changed to optimize the flow uniformity, and any change in size or gap is considered as one design. The results show that some dimple patterns significantly enhance the uniformity compared to baseline, about 4%, while the others slightly reduce it, about 1%. Besides, the dimple pattern also affects to the pressure drop in the flow channel, however the pressure drop in all cases are negligible (less than 26.4 Pa).

• Journal of the Korean Solar Energy Society
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• v.39 no.2
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• pp.1-9
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• 2019

In order to increase the power generation efficiency of the photovoltaic system, a new algorithm that can follow the maximum power point of the photovoltaic power generation system having nonlinear output characteristics is proposed. Conventional maximum power point tracking (MPPT) algorithms such as Perturbation and Observation (P&O) and InCond (Increment and Conductance) schemes can not find the global maximum power point at a plurality of pole points in the unmatched state of unbalanced PV modules. However, even if the global maximum power point is found at a plurality of pole points, the global maximum power that can not be the real maximum power by the photovoltaic generation system. In order to solve this problem, a few PV companies propose installing several small PV inverters instead of if big one. However, since this will require additional costs, we herein propose a Multi-MPPT system using individual 3-point MPPT to track true MPPT at a plurality of pole points in the unmatched state of unbalanced PV modules.

• Korean Journal of Human Ecology
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• v.4 no.1
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• pp.13-29
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• 1995

The purposes of this study are to investigate the characteristics of recognitions and attitudes of new generation family on the family life, and to help the family members of the new generation family to be able to adapt to the future family and society with the right senses and attitudes on the family life. Three-hundred married men and women who were less than 35 years old, and who continued marriage for less than five years were selected. The results of this study were as follow; 1) Types of family composition was mostly nuclear family, and got help from their parents in managing household work. 2) Most new generation family was more likely to share equal roles and rights in household affairs, decision making and ownership of real properties. 3) Most new generation family considered the personality and the sense of value as the most important conditions which their spouse must have. And they were affirmative to wives' employment. 4) Most new generation family wanted 2 children. And preferred showed that they did not care much about son preference. 5) Most new generation family showed strong sense of responsibility for taking care of their old parents. However, they showed independency of financial planning for later years. 6) In many ways of life, their recognitions and attitudes were progressive but their were conservative in practical life as the older generations did.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.26 no.3
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• pp.108-114
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• 2014

On a large scale of data center, heat generation rates from sever computers occupy almost the entire cooling load of the building, and it is gradually increasing. The efficiency of air distribution system in data centers can be affected by heat generation rates of server computers. In this study, the distributions of airflow and temperature in a data center have been investigated by CFD simulations under various conditions of heat generation rates for server computers. From the results, air around the cold aisle which has high temperature flows tremendously into the cold aisle according to the increase of heat generation rates for server computers and the air temperature in the cold aisle becomes higher. The SHI (supply heat index) and RHI (return temperature index) show almost similar values to the cases study because the air inflow rates to server computers increase with the heat generation rates of server computers.