• 한국심리학회지 : 문화 및 사회문제
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• 제20권3호
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• pp.263-280
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• 2014

본 연구는 부모 세대 집단과 청소년 세대 집단이 온라인 게임 인식의 주요 하위 차원인 온라인 게임의 유해성과 유익성, 온라인 게임의 영향과 가치, 온라인 게임과 관련한 부모-자녀 관계, 온라인 게임 규제에 대해 어떠한 생각들을 가지고 있고, 각 세대 집단 간에 어떠한 차이가 있는지를 확인하기 위해 수행하였다. 이를 위해 수도권에 거주하는 중, 고등학생 청소년 155명과 중, 고등학생 부모 192명, 총 347명을 대상으로 온라인 게임 인식 척도 문항을 활용하여 온라인 설문조사를 실시하였다. 연구 결과, 온라인 게임인식의 주요 하위 차원에서 부모 세대 집단과 청소년 세대 집단의 공통점과 차이점을 확인하였다. 특히 온라인 게임의 폭력성과 사회성 항목에서 부모 집단과 청소년 집단의 인식의 차이가 크게 나타나, 이 두영역에 대한 세대 간의 인식의 차이가 온라인 게임을 둘러싼 부모 세대와 청소년 세대의 갈등의 중요한 지점이 되고 있음을 확인하였다. 또한 온라인 게임과 관련한 부모-자녀 관계에 대한 인식에서도 세대 집단 간 차이가 분명하게 드러나, 청소년 시기 발달 과정 속에서의 부모-자녀 관계가 온라인 게임과 관련한 부모-자녀 관계에도 반영되고 있음을 확인하였다. 본 연구는 현실 상황에서 직면하는 구체적인 활동 수준에서 온라인 게임에 대한 세대 집단 간 인식 차이를 세밀하게 조망했다는데 의의가 있다. 또한 온라인 게임과 관련된 부모-자녀 갈등의 원인이 되는 구체적인 지점이 무엇인지 확인하였다는 데에서 실용적인 시사점을 지닌다.

• 대한지역사회영양학회지
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• 제10권5호
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• pp.654-667
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• 2005

To survey the different view points about food service programs among parents and teachers, 2 types of questionnaires, which consisted of attitude, perception, satisfaction and demand of the food service program in child education centers, were used. The data was collected from 2450 parents and 450 teachers who attended a child education center in 16 provinces, nationwide. SPSS was used for descriptive analysis and ANOVA test and $X^2-test$. The frinding results were as follows. 1. The average serving size of meal (lunch) were 80 meals per day and 167 meals per day at large institutions. Mean cost of snacks was 14,709 won per month and mean costs of lunch were 29,319 won per month. The mean price was not significantly different according to the scale of institution. The numbers of servings of lunch, morning snack and afternoon snack were 5, 3.4 and 3.5 times per week each. $56.4\%$ of the institutions served meals to children in classrooms, but the national/public institutions, which were attending elementary school, served meals in a dining place in the elementary school. 2. Teacher controlled serving portion size of snacks $(79.6\%)$ and lunch $(88.8\%)\;and\;30.1\%$ of teacher did not allow leaving lunch food. The ratio of knowing about preserved meals of the teacher who worked at a small institution was significantly higher than the teacher who worked at large institutions (p<0.01). 3. Between parents and teachers, several different view points about school lunch programs were detected. Most parents and teachers wanted that the school lunch to be fully cooked and served at the child education institution itself, but $12.2\%$ of parents and $14.4\%$ of teachers wanted a catering service. The teachers group preferred 'lunch box from home' and 'home partially prepared lunch' as an ideal meal serving type than the parent groups (p<0.01). And there were significantly different view points about price factors in school meals, teachers group highly answered that operating expenses must be added in meal prices. 4. The teacher groups' priorities of education activities during meal time were a significantly lower score than parents group in overall education activities. Teacher and parent groups pointed out that individual sanitation activities were most important of the education activities during meal time, but promoting good eating habits was the lowest score in both groups. 5. 'Improving taste and food quality' was most urgent in food service at child education centers, but there were significantly different view points between parent groups $(64.5\%)$ and teacher groups $(43.8\%)\;(p<0.05)$. They answered at a lower percent in 'employee qualified person' and 'cost control' point to improve food service, but there were also different opinions between the two groups (p<0.01). 6. As to the matter of the advantages and disadvantages of catering services, two group answered that the advantages of a catering service were 'convenience' and 'to solve facilities and labor problems', disadvantages were 'lower in food freshness' and 'sanitation problems'. There were also several different view pionts in catering services, the parents groups were more anxious about food sanitation than teachers. This study found several different view points about school food services among parents and teachers. To improve food services at child education institutions, there is a need to adjust the differences between the two groups through interactive communication channels and education and to employ dietitians as taking charge of adjusting roles between the two groups.

• Journal of Genetic Medicine
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• 제8권1호
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• pp.71-75
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• 2011

임신성 당뇨 및 조기양막파수를 보인 산모의, 다른 산전 병력 없이 과체중아로 태어난 생후 17일된 남아에서, 분만성 상완 신경총 손상, 선천성근성사경 및 구개열의 병발이 진단 되었다. 동시에 세 질환의 병발이 단순 병발일 수 있으나, 세 질환을 동시에 유발할 수 있는 병인에 의한 것일 수 있으므로, 증례의 분석을 통하여 어머니의 임신성 당뇨에 의하여 이 세 질환의 발생이 가능할 것으로 가정하였다. 모체의고혈당증은 주로 신경능선 조직에서 발생하는 태아구조에 영향을 주는 것으로 알려져 있고, 신경능선 조직에서 분화하는 조직들 중 하나인 구개골의 형성에 영향을 주어 구개열의 발생이 가능할 것으로 보이며, 임신성 당뇨에서 과체중아의 출생 빈도가 증가하므로, 이와 관련된 분만 손상 중 분만성 상완 신경총 손상 및 선천성근성사경의 발생이 가능할 것으로 판단된다. 따라서 임신성 당뇨가 있는 산모의 태아에서 구개열등의 선천성 기형의 위험성이 높으므로 산전 검사 시 유의해야하며, 과체중아에서 분만성 상완 신경총 손상과 선천성근성사경의 위험성이 높으므로 이에 대한 주의와 확인이 필요할 것으로 판단된다. 그러나, 분만성 상완 신경총 손상, 선천성근성사경 및 구개열의 병발이 산모의 임신성 당뇨와 연관된 합병증일 수 있다는 것을 증명하기 위하여 향후 더 많은 증례를 통한 심화된 연구가 필요하다.

• Biomolecules & Therapeutics
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• 제25권5호
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• pp.545-552
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• 2017

Increasing concern is being given to the association between risk of cancer and exposure to low-dose bisphenol A (BPA), especially in young-aged population. In this study, we investigated the effects of repeated oral treatment of low to high dose BPA in juvenile Sprague-Dawley rats. Exposing juvenile rats to BPA (0, 0.5, 5, 50, and 250 mg/kg oral gavage) from post-natal day 9 for 90 days resulted in higher food intakes and increased body weights in biphasic dose-effect relationship. Male mammary glands were atrophied at high dose, which coincided with sexual pre-maturation of females. Notably, proliferative changes with altered cell foci and focal inflammation were observed around bile ducts in the liver of all BPA-dosed groups in males, which achieved statistical significance from 0.5 mg/kg (ANOVA, Dunnett's test, p<0.05). Toxicokinetic analysis revealed that systemic exposure to BPA was greater at early age (e.g., 210-fold in $C_{max}$, and 26-fold in AUC at 50 mg/kg in male on day 1 over day 90) and in females (e.g., 4-fold in $C_{max}$ and 1.6-fold in AUC at 50 mg/kg vs. male on day 1), which might have stemmed from either age- or gender-dependent differences in metabolic capacity. These results may serve as evidence for the association between risk of cancer and exposure to low-dose BPA, especially in young children, as well as for varying toxicity of xenobiotics in different age and gender groups.

• Journal of Preventive Medicine and Public Health
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• 제50권6호
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• pp.401-410
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• 2017

Objectives: The purpose of this study was to examine the associations of childbirth, breastfeeding, and their interaction with breast cancer (BC) risk reduction, and to evaluate the heterogeneity in the BC risk reduction effects of these factors by menopause, hormone receptor (HR) status, and pathological subtype. Methods: BC patients aged 40+ from the Korean Breast Cancer Registry in 2004-2012 and controls from the Health Examinee cohort participants were included in this study after 1:1 matching (12 889 pairs) by age and enrollment year. BC risk according to childbirth, breast-feeding, and their interaction was calculated in logistic regression models using odds ratios (ORs) and 95% confidence intervals (CIs). Results: BC risk decreased with childbirth (3+ childbirths relative to 1 childbirth: OR, 0.66; 95% CI, 0.56 to 0.78 and OR, 0.80; 95% CI, 0.68 to 0.95 in postmenopausal and premenopausal women, respectively); and the degree of risk reduction by the number of children was heterogeneous according to menopausal status (p-heterogeneity=0.04), HR status (p-heterogeneity<0.001), and pathological subtype (p-heterogeneity<0.001); whereas breastfeeding for 1-12 months showed a heterogeneous association with BC risk according to menopausal status, with risk reduction only in premenopausal women (p-heterogeneity<0.05). The combination of 2 more childbirths and breastfeeding for ${\geq}13$ months had a much stronger BC risk reduction of 49% (OR, 0.51; 95% CI, 0.45 to 0.58). Conclusions: This study suggests that the combination of longer breastfeeding and more childbirths reduces BC risk more strongly, and that women who experience both 2 or more childbirths and breastfeed for ${\geq}13$ months can reduce their BC risk by about 50%.

• 부모자녀건강학회지
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• 제1권
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• pp.75-87
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• 1998

These days social and economical changes have influence on the structure of family and the role of family members. Working mothers and widowers with children are increasing because of economical difficulties. Support from relatives are decreasing because of the conspicuous trend toward nuclear families. According to these reasons androgynous fathers are required. Today's fathers in Korea socially and culturally have learned about traditional parenting, but they are changing their fathering styles to meet the demands of the times. However they don't have their own fathering models. Therefore nurses who hold an advantageous position to teach and support from clinic have to encourage them to care their infants. The purposes of this study were to define father's care giving in infancy, understand influencing factors on fathering, and the differences between fathering and mothering, then contribute to nursing implementation for supporting fathers. This study was designed to review references about father's care giving. The results were follows: Six aspects of parent participation were direct care. indirect care, play, decision-making concerning the child, amount of time of sole responsibility for the child and overall availability to the child. Direct care involved feeding, bathing, going to child if child awakens. dressing, putting child to bed, taking child to doctor, nurse, or dentist, transporting child to and from sitter, day care, or school, washing child's hair. Indirect care involved cleaning up after child, preparing child's food, fixing child's broken playthings, washing child's clothes, arranging baby-sitting, shopping for child's toys and clothes, transporting baby-sitter to and from your home. Young fathers were gradually participating in direct care like feeding, taking child to doctor. Father's care giving stimulated mothering and promoted parent-infant relationship. Influencing factors of fathering would be divided into father characteristics, surrounding factors, infant attributes. Father characteristics were age, role perception, relationship with parent. Surrounding factors were the opportunity of early contact, support system, spouse's expectation, marital adjustment, feeding type, past experience of care giving. Infant attributes were temperament, behavior, age, sex. The differences between fathering and mothering were reviewed. Fathers were poor at care giving. but their caring was similar to mother's. This subtle difference positively worked upon infant's growth and development. On the basis of these theoretical data, nurses can empower fathers to cooperate with mothers in caring infants.

• 구강회복응용과학지
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• 제28권1호
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• pp.47-56
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• 2012

입술은 사람의 인상을 결정하는 중요한 부분중의 하나이다. 본 연구는 두부계측방사선사진을 이용하여 구호흡자와 비호흡자의 입술두께를 비교하여 구호흡과 하순 두께 변화와의 연관성을 알아보았다. 8세~18세인 아동 및 청소년 436명을 대상으로 두부방사선계측사진을 조사하였다. 전체 조사대상자를 구호흡 그룹과 비호흡 그룹으로만 나누어서 평균과 표준편차를 구한 결과 구호흡 그룹의 하순/상순 비율은 $1.13{\pm}0.14$, 비호흡 그룹의 하순/상순 비율은 $1.02{\pm}0.14$로 나타났다. Skeletal class에 따라 구분한 그룹의 각각의 평균과 표준편차를 살펴보면 skeletal class I은 $1.05{\pm}0.09$, skeletal class II는 $1.20{\pm}0.12$, skeletal class III는 $0.97{\pm}0.11$로 나타났다. 호흡양상에 따라 비교하였을 때 비호흡을 하는 그룹보다 구호흡을 하는 그룹에서 하순/상순 비율이 더 큰 값을 나타내어 하순의 두께가 더 두꺼운 양상을 보였다. Skeletal class에 따라서 비교하였을 때는 skeletal class II 그룹에서 하순/상순 비율이 가장 큰 값을 나타내어 하순의 두께가 가장 두꺼운 양상을 보였다.

• 지역사회간호학회지
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• 제6권2호
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• pp.259-274
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• 1995

The study is to grasp the problems related to operation of Maternity clinic of public health centers in seoul and needs for public health of community in relation to consumers and providers in order to improve efficiency of community public health for mothers and children. Four pregnancy woman, who receive medical care at the maternity clinic of M public health centers in seoul and understand the purpose of this study, and one nurse who works at the were the objects of this field study. Participating observation and intensive interviews were conducted to collect data. All of them were performed as necessary from time to time since December, 1994, and not during a specific period. Through an data analysis in the order of sector analysis and classification analysis, the data were classified into specific patterns and the results are the following; 1. All of the subjects were using both private hospitals and public clinics, but managing activities prior to delivery were not carried out in accordence with theories for those activities. 2. The subjects showed two types of response to utilizing maternity clinic. they answered that the advantages of the clinic were 'short waiting time for medical treatment', 'medical treatment by female doctors' and 'economical benefit.' Meanwhile, they gave negative response to the problems of 'non-implementation of delivery' 'uncleanness and insufficient facilities', 'limited time of treatment', 'lack of expertise' and 'want of public health education for materity.' 3. Problems related to operation of maternity clinic were 'lack of experts', 'irrational facility structure' and 'absolutely lack budget'. In terms of the status of managing the subjects, 'programs only aimed at attaining the central-government-assigned objects' and 'limited management before and after delivery by non-implementing delivery' were pointed out to be problems. Regarding public health education before delivery and PR relations, 'superficial public health education for maternity' and 'absence of PR programs' were named. In planning and evaluation, 'absence of autonomous planning and evaluation by the clinic itself' was a major problem in operating the clinic. 4. 'Substantial health education and PR', 'supplementation of facilities and eqipment', 'development' and supply of demanded service by the subjects', 'implementation of autonomous programs', and 'reinforcement of supplementary education' were presented as alternatives for efficient opration of maternity clinics.

• Biomolecules & Therapeutics
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• 제31권3호
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• pp.350-358
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• 2023

Hand-foot-and-mouth disease (HFMD) is a viral infectious disease that occurs in children under 5 years of age. Its main causes are coxsackievirus (CV) and enterovirus (EV). Since there are no efficient therapeutics for HFMD, vaccines are effective in preventing the disease. To develop broad coverage against CV and EV, the development of a bivalent vaccine form is needed. The Mongolian gerbil is an efficient and suitable animal model of EV71 C4a and CVA16 infection used to investigate vaccine efficacy following direct immunization. In this study, Mongolian gerbils were immunized with a bivalent inactivated EV71 C4a and inactivated CVA16 vaccine to test their effectiveness against viral infection. Bivalent vaccine immunization resulted in increased Ag-specific IgG antibody production; specifically, EV71 C4a-specific IgG was increased with medium and high doses and CVA16-specific IgG was increased with all doses of immunization. When gene expression of T cell-biased cytokines was analysed, Th1, Th2, and Th17 responses were found to be highly activated in the high-dose immunization group. Moreover, bivalent vaccine immunization mitigated paralytic signs and increased the survival rate following lethal viral challenges. When the viral RNA content was determined from various organs, all three doses of bivalent vaccine immunization were found to significantly decrease viral amplification. Upon histologic examination, EV71 C4a and CVA16 induced tissue damage to the heart and muscle. However, bivalent vaccine immunization alleviated this in a dose-dependent manner. These results suggest that the bivalent inactivated EV71 C4a/CVA16 vaccine could be a safe and effective candidate HFMD vaccine.

• Clinical and Experimental Pediatrics
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• 제51권8호
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• pp.812-819
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• 2008

목 적 : 비타민 D는 뼈의 무기질화에 필수적인 역할을 하는 호르몬으로 부족하게 되면 구루병이 생길 수 있다. 본 연구는 비타민 D 결핍증이 잘 발생하는 위험군을 알아보고 그 예방 대책에 대한 관심을 고지하고자 계획하게 되었다. 방 법 : 2003년 3월부터 2007년 7월까지 노원을지병원 소아과에 내원한 환아들중에서 검사 상 우연히 알칼리성인산분해효소가 증가해 있으면서 방사선사진으로 무증상 구루병으로 진단받은 환아들에 대하여 후향적으로 그 특징과 치료 경과를 조사하였다. 결 과 : 남아 6명과 여아 2명의 총 8명이 무증상 구루병으로 진단되었다. 이들의 진단 시 연령은 $12.6{\pm}5.8$개월이었으며, 1월부터 7월 사이에 진단되었고 동반질환으로 폐렴, 요로감염, 장염, 철결핍성 빈혈이 있었다. 이들은 모두 모유 수유를 위주로 하고 있었고, 진단당시 2명의 환아가 몸무게가 3백분위수 미만으로 성장 장애를 보이고 있었다. 진단 시 평균 혈중 알칼리성인산분해효소는 $1,995.8{\pm}739.5IU/L$로 증가되어 있었고, 평균 혈중 칼슘은 $9.5{\pm}0.6mg/dL$, 평균 혈중 인은 $3.6{\pm}1.5mg/dL$였다. 평균 intact-PTH는 $214.8{\pm}155.9pg/mL$로 증가되어 있었고 25-hydroxyvitamin D는 2명을 제외한 6명의 환아에서 30 ng/mL 미만으로 감소되어 있었다. 모든 환자들은 손목 방사선 촬영에서 구루병양 변화를 보이고 있었으나 외관상 골기형이나 발달 장애는 없었다. 이들 중 6명은 3개월간 calcitriol을 투여한 후 생화학적인 검사와 손목 방사선 사진 상의 변화는 호전되었고 정상적으로 성장하였다. 2명은 치료하지 않은 채 저절로 호전되었으며 역시 외관상 성장장애를 보이지는 않았으나 2년간의 추적 관찰 후 현재 1명은 무릎 관절면의 골간단 이형성을 보이고 있으며 다른 1명은 일시적인 척추 측만증을 보였다가 호전되고 있다. 결 론 :무증상 구루병으로 진단된 환아들이 비타민 D 결핍이나 부족으로 인한 것으로 생각되며 모유 수유아에서 비타민 D 결핍증의 빈도가 높으므로 알칼리성인산분해효소가 높은 환자에서는 이를 의심하여 25-hydroxyvitamin D와 손목 방사선 사진을 검사하여 확인하여야 하며 이들 중 일부는 비타민 D 결핍성 구루병으로 진행할 수 있으므로, 모유 수유아에서 비타민 D 보충에 대한 교육이 필요하리라 생각된다.