• Clinical and Experimental Pediatrics
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• v.45 no.10
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• pp.1273-1277
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• 2002

Purpose : To determine clinical features, laboratory findings and cardiac abnormalities of highdose immune globulin(IVIG) retreatment in patients with Kawasaki disease, and to report effectiveness of retreatment. Methods : Retrospective study of 174 children diagnosed with Kawasaki disease at Ewha Mokdong hospital from March, 1999 to July, 2001. Results : Twenty(11.5%) of 174 patients were retreated with high-dose IVIG. After this, only two patients(1.1%) did not respond to IVIG retreatment. Patients with failure to respond to initial IVIG did not differ from the patients who responded to a single course of IVIG in sex, age, days of fever at initial IVIG and clinical characteristics. Compared with responders with single IVIG treatment, the patients who were retreated had significantly lower albumin(3.7 vs 3.4 g/dL, P < 0.05), higher ALT(118.2 vs 229.3 U/L, P < 0.05) and CRP(8.9 vs 13.3 mg/dL, P < 0.05). On echocardiography, patients who recieved IVIG retreatment were significantly more likely to have caronary abnormalities(45.0% vs 13.6%, P < 0.05). Conclusion : Retratment with IVIG for persistent or recurrent fever was safe and effective.

• Journal of the korean academy of Pediatric Dentistry
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• v.39 no.2
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• pp.139-144
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• 2012

The purpose of this study was to evaluate the accuracy and reproducibility of measuring the size of unerupted permanent tooth via cone beam computed tomography(CBCT). Ten children were scanned with dental CBCT, and 3-dimensional reconstruction of the dentitions were generated CBCT. Mesio-distal dimension and buccolingual dimension of the teeth were made directly on the model with a high-precision digitalcaliper and on the CBCT by using three-dimensional dental imaging software. Reliability and accuracy were assessed by using intraclass correlation and paired $t$-tests. ($p$ <0.05) The results were as follows : 1. Intraclass correlations were above 0.9 for Both the CBCT and the model measurements, showinghigh reliability. 2. Although there were high correlation values(r=0.91) between CBCT and model messurement methods, comparisons between the CBCT and model messurement methods showed a statistically significant difference($p$ <0.05). 3. The CBCT measurements tended to slightly underestimate by 0.2 mm. But, the systematic difference of CBCT measurements were clinically acceptable Therefore, CBCT measurement method can be used to measure the size of unerupted teeth in a sufficiently accurate way.

• Journal of the korean academy of Pediatric Dentistry
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• v.29 no.3
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• pp.382-388
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• 2002

In the present study, crown diameters and their sexual differences in deciduous teeth were investigated in children of Chon-ju city, Korea. Plaster casts of the deciduous dentitions obtained from 50 boys and 50 girls were examined. Mesiodistal and buccolingual crown diameters were measured using a digital caliper(0.01mm) according to the definitions of Seipel and Moorees et al. These measurements were performed three times, and intra-observer measurement errors were calculated by the single determination method. The crown index, module and area were calculated in order to provide a comparison of crown proportions. The results obtained were summarized as follows; 1. The mean values of intra-observer measurement errors were 0.255mm and are unlikely to have influenced the statistical analysis. 2. The mean values of mesiodistal and buccolingual crown diameters examined were larger in boys than girls. 3. The mean coefficient of variation was 5.6 in the deciduous dentition. There were a trend for the primary second molar to be the least variable in size of all teeth both in boys and girls. 4. Fluctuating asymmetry is the difference between left and right antimeres in individuals. Primary second molars were less asymmetrical than primary first molars in both dimensions. 5. In maxillary teeth, Crown index is larger in boys than in girls. In contrast, in mandibular teeth, except primary canine, it is larger in girls than in boys. Crown module is larger in boys than in girls and increased progressively from primary first incisor to primary second molar. Crown area is consistently larger in boys than in girls. The minimum crown area is mandibular primary incisor and maximum crown area is maxillary primary second molar.

• Pediatric Infection and Vaccine
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• v.28 no.2
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• pp.110-117
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• 2021

Toxic megacolon is a fatal complication of inflammatory or infectious bowel disease. Prognosis depends on the severity of the disease. In cases of poor prognosis, clinical outcomes range from intestinal resection to death, so early diagnosis and appropriate treatment are very important. However, the prevalence of toxic megacolon in children is very low, and in those without underlying diseases such as inflammatory bowel disease, early diagnosis may be delayed. A previously healthy 12-year-old boy presented to our hospital with lower abdomen pain, fever, and hematochezia. Despite antibiotic therapy, the symptoms worsened. On the third day, abdominal computed tomography revealed severe dilatation of the transverse colon, which indicated toxic megacolon. Stool culture was positive for Salmonella enteritidis group D, and rectal endoscopy showed no signs of inflammatory bowel disease. Ceftriaxone and intravenous methylprednisolone were administered, and the patient's condition improved without any complications. We report a case of toxic megacolon as a complication of infectious colitis caused by S. enteritidis group D, which was diagnosed using early imaging and successfully treated without surgical intervention.

• Journal of Korean Society for Atmospheric Environment
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• v.28 no.5
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• pp.571-580
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• 2012

Epidemiologic studies of air pollution need accurate exposure assessments at unmonitored locations. A land use regression (LUR) model has been used successfully for predicting traffic-related pollutants, although its application has been limited to Europe, North America, and a few Asian region. Therefore, we modeled traffic-related pollutants by LUR then examined whether LUR models could be constructed using a regulatory monitoring network in Metropolitan area in Korea. We used the annual-mean nitrogen dioxide ($NO_2$) in 2010 in the study area. Geographic variables that are considered to predict traffic-related pollutants were classified into four groups: road type, traffic intensity, land use, and elevation. Using geographical variables, we then constructed a model to predict the monitored levels of $NO_2$. The mean concentration of $NO_2$ was 30.71 ppb (standard deviation of 5.95) respectively. The final regression model for the $NO_2$ concentration included five independent variables. The LUR models resulted in $R^2$ of 0.59. The mean concentration of $NO_2$ of elementary schools was 34.04 ppb (standard deviation of 5.22) respectively. The present study showed that even if we used regulatory monitoring air quality data, we could estimate $NO_2$ moderately well. These analyses confirm the validity of land use regression modeling to assign exposures in epidemiological studies, and these models may be useful tools for assessing health effects of long-term exposure to traffic related pollution.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.4
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• pp.301-310
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• 2018

This study was conducted to investigate the relationship between physical function (ADL, IADL) and mental function (depression, cognitive dysfunction) and quality of life in the elderly. The subjects of this study were 524 elderly people aged 65 or older who were admitted to 15 care facilities located in D metropolitan city. Data were collected through a personal interview conducted by interviewers that visited each care facility from November 2015 to January 2016. T-tests and ANOVA were used to compare the quality of life score for each independent variable, while multiple regression was used to determine the explanatory power of independent variables that affected quality of life. Quality of life was significantly lower among those of older age, lower educational level, living alone, with lower relationships with children, lower subjective health status, disability, lower ability for mastication, without regular eating habits, without regular exercise, and without regular health checkups. In addition, quality of life was significantly lower in the ADL and IADL, as well as among those with a higher depression level and lower cognitive impairment scores than their respective counterparts. The results of this study suggest that the quality of life among elderly that have been admitted to care facilities is significantly related to physical and mental functions as well as demographic characteristics, health status and health related behavioral characteristics.

• Journal of Korean Neurosurgical Society
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• v.49 no.3
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• pp.147-152
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• 2011

Objective : The aim of this study was to evaluate the reliability and validity of the Pediatric Functional Assessment of Cancer Therapy Questionnaire Brain Tumor Survivor (version 2.0) Aged 13 years and older (Parent Form) (pedsFACT-BrS parent of adolescent). Methods : The pedsFACT-BrS parent of adolescent was translated and cross-culturally adapted into Korean, following standard Functional Assessment of Chronic Illness Therapy (FACIT) methodology. The psychometric properties of the pedsFACT-BrS parent of adolescent were evaluated in 170 brain tumor patient's mothers (mean age=43.38 years). Pretesting was performed in 30 mothers, and the results indicated good symptom coverage and overall comprehensibility. The participants also completed the Child Health Questionnaire Parent Form 50 (CHQ-PF-50), Neuroticism in Eysenck Personality Questionnaire, and Karnofsky score. Results : In validating the pedsFACT-BrS parent of adolescent, we found high internal consistency, with Cronbach's ${\alpha}$ coefficients ranging from 0.76 to 0.94. The assessment of test-retest reliability using intraclass correlation coefficient revealed satisfactory values with ICCs ranging from 0.84 to 0.93. The pedsFACT-BrS for parent of adolescent also demonstrated good convergent and divergent validities when correlated with the Child Health Questionnaire Parent Form 50 (CHQ-PF-50) and the Neuroticism in Eysenck Personality Questionnaire. The pedsFACT-BrS parent of adolescent showed good clinical validity, and effectively differentiated between clinically distinct patient groups according to the type of treatment, tumor location, shunt, and Karnofsky score of parent proxy report. Conclusion : We confirmed that this reliable and valid instrument can be used to properly evaluate the quality of life of Korean adolescent brain tumor patients by their parents' proxy report.

• Journal of dental hygiene science
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• v.6 no.2
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• pp.79-84
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• 2006

The purpose of this study was to collect base-data for evaluation of primary school oral health program. The data was Obtained from 648 children of four primary schools in Gwangiu city, Gyeonggi-Do Korea, during 2 month (March to May, 2006). The survey was performed by a face-to-face interview questionnaire consisting of OIDP. We analyzed knowledge, attitude, action and DMFT, oral health knowledge, the state satisfaction, no dental treatment need according to being or not being of the score using SPSS 12.0. ODIP score measure was based on scoring method for OIDP. The results were as follows. 1. In knowledge, attitude, behavior of oral hygiene with regard to OIDP score, he group with OIDP score is higher than the group without that and in case of knowledge and behavior, the group with OIDP score has a significant difference from the group without (p < 0.05). 2. In case of the oral hygiene cognition, a situation satisfaction, a no dental treatment need based on OIDP score, the group without OIDP score has a desirable andsignificant difference from the group with OIDP score (p < 0.05). 3. In case of DMFT based on OIDP score, the group with has a higher DMFT than the group without and has an significant difference from the group without (p < 0.05).

• Journal of Bone Metabolism
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• v.25 no.4
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• pp.195-211
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• 2018

Background: To develop guidelines and recommendations to prevent and treat glucocorticoid (GC)-induced osteoporosis (GIOP) in Korea. Methods: The Korean Society for Bone and Mineral Research and the Korean College of Rheumatology have developed this guideline based on Guidance for the Development of Clinical Practice Guidelines ver. 1.0 established by the National Evidence-Based Healthcare Collaborating Agency. This guideline was developed by adapting previously published guidelines, and a systematic review and quality assessment were performed. Results: This guideline applies to adults aged ${\geq}19years$ who are using or plan to use GCs. It does not include children and adolescents. An initial assessment of fracture risk should be performed within 6 months of initial GC use. Fracture risk should be estimated using the fracture-risk assessment tool (FRAX) after adjustments for GC dose, history of osteoporotic fractures, and bone mineral density (BMD) results. All patients administered with prednisolone or an equivalent medication at a dose ${\geq}2.5mg/day$ for ${\geq}3months$ are recommended to use adequate calcium and vitamin D during treatment. Patients showing a moderate-to-high fracture risk should be treated with additional medication for osteoporosis. All patients continuing GC therapy should undergo annual BMD testing, vertebral X-ray, and fracture risk assessment using FRAX. When treatment failure is suspected, switching to another drug should be considered. Conclusions: This guideline is intended to guide clinicians in the prevention and treatment of GIOP.

• Korean Journal of Radiology
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• v.22 no.7
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• pp.1172-1184
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• 2021

Objective: The purposes of this study were to analyze the radiation doses for pediatric abdominopelvic and chest CT examinations from university hospitals in Korea and to establish the local diagnostic reference levels (DRLs) based on the body weight and size. Materials and Methods: At seven university hospitals in Korea, 2494 CT examinations of patients aged 15 years or younger (1625 abdominopelvic and 869 chest CT examinations) between January and December 2017 were analyzed in this study. CT scans were transferred to commercial automated dose management software for the analysis after being de-identified. DRLs were calculated after grouping the patients according to the body weight and effective diameter. DRLs were set at the 75th percentile of the distribution of each institution's typical values. Results: For body weights of 5, 15, 30, 50, and 80 kg, DRLs (volume CT dose index [CTDI_vol]) were 1.4, 2.2, 2.7, 4.0, and 4.7 mGy, respectively, for abdominopelvic CT and 1.2, 1.5, 2.3, 3.7, and 5.8 mGy, respectively, for chest CT. For effective diameters of < 13 cm, 14-16 cm, 17-20 cm, 21-24 cm, and > 24 cm, DRLs (size-specific dose estimates [SSDE]) were 4.1, 5.0, 5.7, 7.1, and 7.2 mGy, respectively, for abdominopelvic CT and 2.8, 4.6, 4.3, 5.3, and 7.5 mGy, respectively, for chest CT. SSDE was greater than CTDI_vol in all age groups. Overall, the local DRL was lower than DRLs in previously conducted dose surveys and other countries. Conclusion: Our study set local DRLs in pediatric abdominopelvic and chest CT examinations for the body weight and size. Further research involving more facilities and CT examinations is required to develop national DRLs and update the current DRLs.