• Molecules and Cells
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• 제46권11호
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• pp.672-674
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• 2023

Schematic diagram of the interaction between the intestinal muscularis externa (MMΦ) macrophages and the enteric nervous system (ENS) neurons during different developmental periods. At the early postnatal stage, MMΦs play a critical role in ENS maturation and refinement through synaptic pruning and enteric neuron phagocytosis. In addition, during the adult stage, a specific MMΦ subset named neuron-associated (NA)-MMΦ, supports enteric neuronal survival and functions. Conversely, enteric neurons promote the phenotypic MMΦ changes by secreting transforming growth factor-β (TGFβ), transitioning them from a phagocytic phenotype in the early postnatal period to a neuroprotective and immune-surveillant phenotype in the young adult period. Disruptions in these interactions could lead to alterations in the enteric neuron numbers, ultimately resulting in reduced gut motility.

• 성인간호학회지
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• 제13권2호
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• pp.191-199
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• 2001

This study was undertaken to find out the perception of marital relationship and to understand the typology. The Q-population consisted of 153 statements that were collected and 33 Q-samples were selected. The P-samples for this study were made up of 30 who were married. Each responded to a Q-set of marital relationship according to 9-point scale. The results of Q-sorting were coded and analysed using QUANL PC program. Typological observations were as follows. 1) One in body and spirit type : In type 1, couples had different backgrounds respectively but felt one in body and spirit. 2) Companionship type : 2. Couples had not so much a hierarchial as a horizontal relationship. Couples perceived themselves as interdependent and friends. 3) Adaptation type : Couples readily adapted themselves to a marital relationship. They only depended on their spouses at times and stressed the relationship. Marriage was accepted as destiny rather than choice. On the basis of these results, we suggest: When a marriage is in trouble, that we assess the type of marital relationship in advance and intervene with a proper program. In addition, practical intervention programs need to be developed tailored to the type of subjective perception about the marital relation

• 성인간호학회지
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• 제13권1호
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• pp.136-147
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• 2001

Dysphagia is common and serious problem in intracerebral hemorrhage patients. Nasogastric-tube intubation is an important method for dysphagic patients who have an intracerebral hemorrhage. But many discomforts develope in patients with a nasogastric-tube. Therefore, it is necessary to decide when to remove the tube and as early as possible. The purpose of this study is to decide the applying time of training program to facilitate deglution for dysphagic patients who have intracerebral hemorrhage. Among the 343 patients with intracerebral hemorrhage who had been admitted to P-university hospital from April, 1994 to December, 1998, the medical record of the 110 patients with nasogastric tube were reviewed retrospectively. Results from the study were as follows: 1. Nasogastric tube insert duration of improved patients was a mean of 23.2 days 2. When a L-tube was inserted and removed, the L.O.C. of improved patients was $2.6{\pm}0.8$(in the midst of stupor or a semicoma),$1.9{\pm}0.5$(close to drowsy), respectively. This was signifcantly different(P=0.000). 3. When a L-tube was inserted and removed, GCS of improved patients was $9.3{\pm}2.9$, $12.1{\pm}2.2$ respectively. This was significantly different (P=0.000). 4. The duration of nasogastric tube insertion was the longest when in a stupor(L.O.C), 6~8 points(GCS).

• 성인간호학회지
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• 제16권4호
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• pp.626-635
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• 2004

Purpose: The purpose of this study was to explain the effects of upper extremity exercise program on hemiplegic stroke patients. Method: The research was designed by a non-equivalent pretest-posttest way. The data were collected from February to August 2003 at a community health center located in Seoul. The study subjects were a conveniently selected group of 27 hemiplegic patients. The subjects were divided into two groups, the experimental group and the control group. 14 subjects were assigned to the experimental group in which the subjects did the upper extremity exercise training for 2 hours once a week during four weeks, while 13 subjects were assigned to the control group. The outcomes were evaluated on the basis of the upper extremity motor ability(hand power, pinch power, upper extremity ROMs), amount of motor use and the degree of depression. Result: 1. After treatment, the motor abilities of the affected upper extremity(hand power, pinch power, ROMs of wrist flexion/extension, shoulder extension) were significantly different between the two groups. However, there were no significant differences in elbow and shoulder flexion between experimental and control group. 2. After treatment, amount of motor use of affected upper extremity were significantly different between the two groups. 3. After treatment, the degree of depression were significantly different between the two groups. Conclusion: In considering these results, the upper extremity exercise program could be effective for hemiplegic patients by improving the function of their upper extremity. Long-term studies are needed to determine the effects of upper extremity exercise program.

• 성인간호학회지
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• 제16권1호
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• pp.82-89
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• 2004

Purpose: The purpose of this study was to investigate the effect of nursing education using a CD ROM on the anxiety and knowledge of the patients having minor surgery. Method: Forty patients hospitalized in K hospital in Seoul from April to August 2002 participated in this study. In the experimental group, twenty patients received nursing education on the operational procedures and post-operational care. The control group, received conventional nursing care only. Anxiety experienced by patients was measured by Spielberger's State-Trait Anxiety Inventory, and knowledge was measured by an instrument developed by Rahe et al. The data were analyzed by SPSS statistical program. Result: There were no significant differences in anxiety level between two groups. However, subjects in the experimental group were found to have significantly higher postoperative knowledge levels than those in the control group, and were very satisfied with the CD ROM program. Conclusion: The nursing education program using CD ROM before minor surgery proved to be an effective nursing intervention to increase knowledge of patients and contribute to their self care after discharge. To decrease anxiety of the surgery, the nursing education program should be combined with supprortive emotional nursing intervention, such as touch, and massage.

• 성인간호학회지
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• 제20권6호
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• pp.815-828
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• 2008

Purpose: This study was to develop and evaluate the clinical utility of the breast and ovarian cancer genetic counselling program specific for 20 Korean women(KBOCGP). Methods: The KBOCGP was developed using three types of approaches: an ethnography among Korean women who underwent BRCA1/2 test, designing and implementing one week clinical genetic educational course for clinical cancer nurses, educational observation visits to three American cancer genetic counselling programs. And then pre-experimental design was implicated to evaluate the change of the women's knowledge about the hereditary breast and ovarian cancer and the level of the satisfaction with genetic counselling. Results: The mean score of the knowledge has significantly increased from $7.45{\pm}3.86$ to $11.55{\pm}2.21$ (t = 5.63, p < .001). The level of the satisfaction with the counselling was very high ($27.47{\pm}1.35$). Because most of the subjects have young kids, they showed strong concerns about their kids' getting cancer. Conclusion: This new KBOCGP is the satisfactory program for the education and communication of the genetic information to the Korean women with HBOC. But it is needed more to strengthen the cultural sensitivity especially to Korean family relationships. Authors recommend that this program be provided by other nurses who are counselling women at high risk of breast cancer.

• 한국전문물리치료학회지
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• 제5권3호
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• pp.63-71
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• 1998

Trunk holding test (Sorensen test) appear to have more value than strength test in prediction the occurrence of low back pain. Electromyographic activity of trunk extensor muscles during these test may provide clues to the etiology of neuromuscular-based low back pain. This study investigated the difference in back muscle endurance between healthy adult men and women using surface electromyographic (EMG) power spectral analysis. Thirty hea1thy subjects (15 men and 15 women) performed an unsupported trunk holding test for 60 seconds. Recording surface electrodes were placed over the erector spinae medially and laterally at vertebral levels of $L_1$ and $L_5$. Slope of total frequency was evaluated using the MP100WSW Fast Fourier Transform spectrum analysis program. The slopes of all indices of back muscle fatigue, except right $L_5$, were significantly steeper in men than in women (p<0.05). Our results indicated that the trunk holding test using EMG power spectral analysis of erector spinae muscles is useful for the evaluation of fatigue rate of these muscles. Our results also showed a higher muscle endurance in healthy adult women than in men.

• 기본간호학회지
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• 제12권1호
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• pp.6-14
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• 2005

Purpose: This study was done to investigate the need to develop health promotion programs for adult women and to compare lifestyle, health status and quality of life in adult women in urban and rural areas. Method: The participants were women over 20 years old, 451 living in 3 cities and 436 living in 1 rural areas. Data collection was conducted from April 6 to August 30, 2004. Results: For lifestyle, the percentage of women having regular medical examinations, cholesterol tests, regular exercise, and high alcohol intake were significantly higher for urban women compared to the rural women. For health status, the percentage of women with health problems such as arthritic pain, urinary incontinence, pregnancy and postpartum complications, and the experience of violence were significantly higher for rural women compared to urban women. Rural women had significantly lower scores for health perception compared to urban women. For quality of life, rural women had significantly higher scores for quality of life, especially for the psychological wellbeing and stability subscales. Conclusion: The above findings indicate that it is necessary to develope a health promotion program which reinforces healthy lifestyle and health status for rural women, and quality of life, for urban women.

• Animal cells and systems
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• 제15권4호
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• pp.268-273
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• 2011

Transgenic mice expressing green fluorescent protein (GFP) under the control of human glial fibrillary acidic protein promoter (hGFAP) have been utilized for in vivo labeling of astrocytes. Although it has been considered that virtually all astrocytes express GFP in this transgenic mouse, we found that different subsets of GFAP-expressing astrocytes express considerably different levels of GFP in the adult brain. Astrocytes in the spinal cord, the molecular layer of thecerebellum, meninges, white matter, corpus callosum and blood vessels exhibited strong GFP, whereas subsets of astrocytes associated with granule cells in the cerebellum and dentate gyrus did not or only marginally exhibited GFP. We also found that a small subset of GFP-expressing cells in the periglomeruli of the olfactory bulb did not express GFAP immunoreactivity. Collectively, these results suggest that human GFAP promoter-derived GFP expression does not faithfully recapitulate the endogenous GFAP expression in mice, suggesting that upstream regulatory mechanisms controlling GFAP transcription are different in different populations of astrocytes, and may reflect the functional diversity of astrocytes.

• 대한간호학회지
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• 제37권7호
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• pp.1073-1079
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• 2007

Purpose: The purpose of this study was to identify the effects of a smoking cessation program on the amount of smoking and nicotine dependence and the self-efficacy of smoking cessation for smoking workers. Methods: The total number of subjects was 38 smokers and was divided into two: 16 smokers were placed in the experimental group and 22 in the control group. A nonequivalent control group pretest-posttest design was used. The smoking cessation program consisted of two sessions and was implemented for two hours daily for five days. Data was analyzed by using the SPSS/WIN 11.0 program with $X^2-test$, t-test or Mann-Whitney U and ANCOVA. Results: After the treatment, those belonging to the experimental group showed a significantly decreased amount of smoking, a decreased nicotine dependency and increased self-efficacy compared to the control group. Conclusion: The smoking cessation program was effective for diminishing the amount of smoking, decreasing nicotine dependence and improving self-efficacy. Therefore, this program is recommended as a smoking cessation strategy for adult smokers.