• 생약학회지
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• 제49권1호
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• pp.65-69
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• 2018

Torilin is a major sesquiterpene of Torilis japonica (Umbelliferae) fruits and known to be a melanogenesis inhibitor. Extraction conditions are important factor for the efficient preparation to save cost and time in economic aspects. For this reason, this study was conducted to optimize the extraction condition for maximal yield of torilin. For optimization, extraction factors such as extraction solvent, extraction temperature and sample/solvent ratio were tested and optimized for maximum yield of torilin using response surface methodology with Box-Behnken design (BBD). The optimal condition was obtained as a EtOAc concentration in MeOH of 31.8%, an extraction temperature at $30.3^{\circ}C$ and a sample/solvent ratio, 1000 mg/2 ml. The torilin yield under optimal conditions was found to be 9.9 mg/g dried samples, which were well-matched with the predicted value of 10.4 mg/g dried samples. These results will provide useful information about optimized extraction conditions for the development of torilin as cosmetic therapeutics to reduce skin hyperpigmentation.

• 한국염색가공학회지
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• 제23권1호
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• pp.11-20
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• 2011

UV-induced surface copolymerization has been widely applied as a simple, useful and versatile approach to improve the surface properties of textiles. C.I. Reactive Black 5 and acrylic acid (AA) were continuously grafted onto cotton by UV irradiation. The photografting may occur by the copolymerization of AA with the vinylsulfone reactive dye which photochemically converted from the bissulfatoethylsulfone reactive group. The graft yield and color yield were influenced by UV energy, the dye and photoinitiator concentrations, a mole ratio of AA to dye, and pH. The coloration of cotton fabrics having a K/S of 7.0 can be obtained under a UV irradiation energy of 15$J/cm^2$ by the photografting of an aqueous alkaline formulation of 6% dye concentration containing 3% photoinitiator concentration on the weight of monomers, and a 3:1 mole ratio addition of AA to the dye. Furthermore, the photochemically dyed cotton fabrics showed comparable washing (staining) and rubbing fastness to conventional reactive dyeing method except shade change in the wash fastness and light fastness.

• Journal of Microbiology and Biotechnology
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• 제24권11호
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• pp.1542-1550
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• 2014

Co-digesting molasses wastewater and sewage sludge was evaluated for hydrogen production by response surface methodology (RSM). Batch experiments in accordance with various dilution ratios (40- to 5-fold) and waste mixing composition ratios (100:0, 80:20, 60:40, 40:60, 20:80, and 0:100, on a volume basis) were conducted. Volatile solid (VS) concentration strongly affected the hydrogen production rate and yield compared with the waste mixing ratio. The specific hydrogen production rate was predicted to be optimal when the VS concentration ranged from 10 to 12 g/l at all the mixing ratios of molasses wastewater and sewage sludge. A hydrogen yield of over 50 ml $H_2/gVS_{removed}$ was obtained from mixed waste of 10% sewage sludge and 10 g/l VS (about 10-fold dilution ratio). The optimal chemical oxygen demand/total nitrogen ratio for co-digesting molasses wastewater and sewage sludge was between 250 and 300 with a hydrogen yield above 20 ml $H_2/gVS_{removed}$.

• Computers and Concrete
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• 제8권4호
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• pp.371-388
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• 2011

In this paper, time-continuous constitutive equations for strain rate-dependent materials are presented first, among which those for the overstress and the consistency viscoplastic models are considered. By allowing the stress states to be outside the yield surface, the overstress viscoplastic model directly defines the flow rule for viscoplastic strain rate. In comparison, a rate-dependent yield surface is defined in the consistency viscoplastic model, so that the standard Kuhn-Tucker loading/unloading condition still remains true for rate-dependent plasticity. Based on the formulation of the consistency viscoplasticity, a computational elasto-viscoplastic constitutive model is proposed for the short fiber-reinforced fresh cementitious paste for extrusion purpose. The proposed constitutive model adopts the von-Mises yield criterion, the associated flow rule and nonlinear strain rate-hardening law. It is found that the predicted flow stresses of the extrudable fresh cementitious paste agree well with experimental results. The rate-form constitutive equations are then integrated into an incremental formulation, which is implemented into a numerical framework based on ANSYS/LS-DYNA finite element code. Then, a series of upsetting and ram extrusion processes are simulated. It is found that the predicted forming load-time data are in good agreement with experimental results, suggesting that the proposed constitutive model could describe the elasto-viscoplastic behavior of the short fiber-reinforced extrudable fresh cementitious paste.

• 한국수산과학회지
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• 제54권1호
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• pp.9-15
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• 2021

Sargassum serratifolium is a rich source of antioxidant meroterpenoids. The optimal extraction temperature and time for obtaining maximal antioxidant yield, antioxidant activity, and phenolic content from Sargassum serratifolium were determined using response surface methodology (RSM). The ranges of the independent variables for extraction temperature and time were 30-70℃ and 12-36 h, respectively. With increasing temperature and time, the yield increased significantly, while DPPH (2,2-dipheny-1-picrylhydrazyl) radical-scavenging activity and total phenolic content decreased significantly. The optimal extraction temperature and time obtained by RSM were 54℃ and 7 h, respectively, providing a yield of 8.2%, DPPH radical-scavenging activity of 60%, and total phenolic content of 163 mg GAE/g. The findings of this study provide useful information for the development of Sargassum serratifolium extraction processes for the food and cosmetic industries.

• 생약학회지
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• 제53권4호
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• pp.202-206
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• 2022

Salidroside is a major phenolic glycoside of Acer tegmentosum (Aceraceae) and known to be a hepatoprotective compound. Extraction conditions are one of the most important factors to save time and cost from an economic point of view. For this reason, this study was conducted to optimize the extraction condition for maximum yield of salidroside. For optimization, three extraction factors such as ethanol concentration (%), extraction temperature (℃), and solvent to material ratio (mg/mL) were tested and optimized for maximum yield of salidroside using response surface methodology (RSM). The optimal condition was obtained as an ethanol concentration of 53.4%, an extraction temperature at 67.11℃ and a solvent to material ratio (mg/mL), 195.55 mg/ml. The salidroside yield under optimal conditions was found to be 1.59 mg/g dried samples, which were well-matched with the predicted value of 1.56 mg/g dried samples. These results will provide useful information about optimized extraction conditions for the development of salidroside as hepatoprotective therapeutics.

• 한국산림과학회지
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• 제99권4호
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• pp.534-545
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• 2010

산불피해지의 급경사면에 있어서 지표토사의 침식에 영향을 미치는 강우의 형태와 강도를 산불의 피해강도 및 경과년수별로 파악하고, 그에 따른 침식토사량의 변화와 그 원인을 해석하기 위해 2000년도에 발생한 산불피해지 가운데 강원도 삼척시 인근지역을 대상으로 저 중 고강도산불피해를 입은 산림에 각각 3개소씩, 총 9개의 조사구를 선정하여 침식토사량을 측정하였다. 그 결과, 산불피해의 강도가 감소함에 따라, 그리고 산불발생 후의 경과년수가 증가함에 따라 지표토양의 침식에 영향을 미치는 강우형태는 일강우량에서 실효우량으로 변화하였으며, 토양침식에 영향을 미치는 강우강도는 점차 증가하는 것으로 나타났다. 산불이 발생하게 되면 식생에 의한 강우차단이 저감될 뿐만 아니라 토양공극이 감소되어 침투능 역시 저하되며, 이러한 유수의 표면유출에 관여하는 물리적 생태학적 조건은 산불피해의 강도 및 경과년수에 따라 다양화된다. 이러한 현상은 산불피해지의 토양침식에 직접적인 영향을 미쳐 산불피해의 강도가 감소함에 따라, 그리고 산불발생 후의 경과년수가 증가함에 따라 침식토사량은 경감되었으며, 그 증가추세 역시 감소되는 것으로 나타났다. 따라서 산불피해지의 다양한 물리적 생태학적 조건을 고려한 종합적인 복원 및 관리방안의 수립이 절실히 요구된다.

• 소성∙가공
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• 제9권4호
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• pp.372-378
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• 2000

A process model including the effects of both the texture development and ductile damage evolution In plane strain rolling is presented. In this process model, anisotropy from deformation texture and deterioration of mechanical properties due to growth of micro voids are directly coupled Into the virtual work expressions for the momentum and mass balances. Special treatments in obtaining the initial values of field variables in the nonlinear simultaneous equations for the anisotropic, dilatant viscoplastic deformation are also given. Mutual effects of the texture development and damage evolution during plate rolling are carefully examined in terms of the distribution of strain components, accumulated damage, R-value as well as yield surfaces.

• Steel and Composite Structures
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• 제3권4호
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• pp.231-242
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• 2003

This paper deals with the formulation and development of fracture criteria for high-strength structural members containing surface damage in the form of notches (i.e., blunt defects). The important role of the yield strength of the material and its strain hardening capacity (evaluated by means of the constitutive law or stress-strain curve) is analysed in depth by considering the fracture performance of notched samples taken from high-strength steels with different levels of cold drawing (the most heavily drawn steel being commercial prestressing steel used in prestressed concrete). The final aim of the paper is to establish fracture-based design criteria for structural members made of steels with distinct yield strength and containing very different kinds of notch-shape surface damage.

• 생명과학회지
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• 제12권6호
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• pp.765-768
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• 2002

Rhodotorula sp. CL-82 유래 의 epoxide hydrolase 활성을 이용하여 라세믹 styrene oxide에 대한 입체선택적 가수분해 반응을 실시하였다. Rhodotorula sp. CL-82 생촉매의 입체선택적 가수분해속도를 나타내주는 반응표면 곡선에 대한 분석을 통해 pH, 반응주도, cosolvent 첨가량에 대한 최적조건을 각각 7.6,$33.3^{\circ}C$ , 3%(v/v)으로 결정하였다. 최적반응조건에서 약 4시간 정도의 반응을 통해 ee값이 99% 이상인 광학적으로 순수한 (S)-styrene oxide를 이론 수율대비 40% 수율로 얻을 수 있었다.