• Biomolecules & Therapeutics
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• v.30 no.3
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• pp.246-256
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• 2022

The present study focused on the potential mechanism of betulin (BT), a pentacyclic triterpenoid isolated from the bark of white birch (Betula pubescens), against chronic alcohol-induced lipid accumulation and metaflammation. AML-12 and RAW 264.7 cells were administered ethanol (EtOH), lipopolysaccharide (LPS) or BT. Male C57BL/6 mice were fed Lieber-DeCarli liquid diets containing 5% EtOH for 4 weeks, followed by single EtOH gavage on the last day and simultaneous treatment with BT (20 or 50 mg/kg) by oral gavage once per day. In vitro, MTT showed that 0-25 mM EtOH and 0-25 µM BT had no toxic effect on AML-12 cells. BT could regulate sterolregulatory-element-binding protein 1 (SREBP1), lipin1/2, P2X7 receptor (P2X7r) and NOD-like receptor family, pyrin domains-containing protein 3 (NLRP3) expressions again EtOH-stimulation. Oil Red O staining also indicated that BT significantly reduced lipid accumulation in EtOH-stimulated AML-12 cells. Lipin1/2 deficiency indicated that BT might mediate lipin1/2 to regulate SREBP1 and P2X7r expression and further alleviate lipid accumulation and inflammation. In vivo, BT significantly alleviated histopathological changes, reduced serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) and triglyceride (TG) levels, and regulated lipin1/2, SREBP1, peroxisome proliferator activated receptor α/γ (PPARα/γ) and PGC-1α expression compared with the EtOH group. BT reduced the secretion of inflammatory factors and blocked the P2X7r-NLRP3 signaling pathway. Collectively, BT attenuated lipid accumulation and metaflammation by regulating the lipin1/2-mediated P2X7r signaling pathway.

• Proceedings of the Plant Resources Society of Korea Conference
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• 1998.10a
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• pp.48-50
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• 1998

• Journal of the Korean Society of Food Culture
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• v.32 no.3
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• pp.215-226
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• 2017

This study aimed to investigate the perception and preferences related to Korean food according to the ethnicity of university students in Yanbian, China. Korean food was preferred by Korean-Chinese as compared with Chinese students, and Korean-Chinese students preferred Korean food more than Chinese food. Both Korean-Chinese and Chinese preferred Korean food more than traditional Chosun food. More Korean-Chinese than Chinese students had positive perceptions of Korean food, which included foods made with jang, kimchi smell, and healthiness due to diversity. For evaluation of Korean food taste, more Chinese than Korean-Chinese subjects thought Korean food is not greasy and hoped salty taste. Both awareness and preferences related to Korean food were significantly higher in Korean-Chinese than Chinese students. Meat foods (so-galbi, dak-galbi, jang-jorim) were relatively high in terms of preference in both Korean-Chinese and Chinese students. Moreover, Chinese students preferred Korean traditional foods (sujeonggwa, yakgwa, gangjeong). In Korean-Chinese students, Korean representative traditional foods (kimchi, jangajji) and Korean traditional holiday foods (tteokguk, mandu-guk) were relatively low in terms of preference. This study found that the traditional food culture of Korean-Chinese has been maintained in Yanbian, whereas there is a change in the young generation.

• Journal of Families and Better Life
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• v.24 no.4 s.82
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• pp.25-36
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• 2006

The purpose of this study is to investigate the parenting stress, efficacy, and behaviors of Korean and Yanbian Korean-Chinese grandfamilies in which grandparents have sole responsibility for raising their grandchildren. Our sample consists of 74 grandparents and their grandchildren (43 Korean and 31 Yanbian Korean-Chinese). The data were analyzed through crosstabs analysis, 1-test, Pearson's correlation, and stepwise regression analysis. The results of this study indicate that there are some differences based on the gender of grandparents, educational level, the reason for taking care of the grandchildren, and the grandparents' relationship with grandchildren between two ethnic groups. The results also show that parenting stress is higher for Korean grandparents' and parenting efficacy is lower than Yanbian Korean-Chinese. Also, Yanbian Korean-Chinese grandparents are higher in warmth and acceptance and lower in rejected and controlled parenting behaviors than Korean grandparents. There are strong relationships between parenting stress and parenting efficacy and between parenting behaviors and parenting stress and parenting efficacy for Korean grandparents, but not for Yanbian Korean-Chinese.

• Journal of the Korean Society of Costume
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• v.65 no.7
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• pp.1-18
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• 2015

The purpose of this paper is to compare the body types of Korean-Chinese and Han-Chinese women in their 60's dwelling in Yanbian Korean Autonomous Prefecture. In addition, a survey was conducted to analyze the social and environmental factors that would decide the body types of these two groups of individuals. 1) The comparison of 74 items in physical measurements between the Korean-chinese and Han-chinese showed differences in 36 items. 2) As for the body measurements of women, difference was found between the Han-Chinese and Korean-Chinese in all height items except bust height, circumference, depth, length, and weight. The values of Korean-Chinese were lower than those of Han-Chinese. 3) Cluster analysis shows that Korean- Chinese women appear thinner in regards to common weight, while Han-Chinese women appear to be thicker in regards to with common thinness. 4) Korean-Chinese women dwelling in Yanbian Korean Autonomous Prefecture maintained unique traditional customs and eating habits of Korea and were in constant contact with Korean cultures, which seems to make them care more about body management for health and beauty.

• Biomolecules & Therapeutics
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• v.28 no.4
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• pp.320-327
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• 2020

In current study, we aimed to investigate whether the gentiopicroside (GPS) derived from Gentiana manshurica Kitagawa could block the progression of alcoholic hepatic steatosis to fibrosis induced by chronic ethanol intake. C57BL/6 mice were fed an ethanol-containing Lieber-DeCarli diet for 4 weeks. LX-2 human hepatic stellate cells were treated with GPS 1 h prior to transforming growth factor-β (TGF-β) stimulation, and murine hepatocyte AML12 cells were pretreated by GPS 1 h prior to ethanol treatment. GPS inhibited the expression of type I collagen (collagen I), α-smooth muscle actin (α-SMA) and tissue inhibitor of metal protease 1 in ethanol-fed mouse livers with mild fibrosis. In addition, the imbalanced lipid metabolism induced by chronic ethanol-feeding was ameliorated by GPS pretreatment, characterized by the modulation of lipid accumulation. Consistently, GPS inhibited the expression of collagen I and α-SMA in LX-2 cells stimulated by TGF-β. Inhibition of lipid synthesis and promotion of oxidation by GPS were also confirmed in ethanol-treated AML12 cells. GPS could prevent hepatic steatosis advancing to the inception of a mild fibrosis caused by chronic alcohol exposure, suggesting GPS might be a promising therapy for targeting the early stage of alcoholic liver disease.

• Journal of the Korean Society of Food Culture
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• v.16 no.4
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• pp.341-353
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• 2001

This study was conducted to investigate dietary patterns and assimilation of dietary culture of Korean descendants in Yanbian, China compared to Korean. A dietary survey was conducted using one 24-hour recall method from 730 adults over 30 years of age in Yanbian, China and 695 adults over 25 years of age in Kuri, Korea. The average number of food items consumed per day was 14 in Yanbian and 20 in Kuri and there was a significant difference between the two regions(p<0.001). The foods consumed most frequently were rice, salt, the M.S.G. in Yanbian and rice, green onion and garlic in Kuri. The foods consumed most by amount were rice, cucumber, Soju in Yanbian and rice, Kimchi and grape in Kuri. The average number of dishes consumed per day was 6.4 in Yanbian, 9.4 in Kuri and the difference between the two regions was significant(p<0.001). Total number of dishes appeared in the survey was 253 in Yanbian and 494 in Kuri. The dishes consumed most frequently were cooked-rice, beverages, Kimchi, stir-fried eggplant in Yanbian and cooked-rice, Kimchi, coffee, soybean paste stew, in Kuri. The dish groups appeared most frequently were rice, stir-fried foods, vegetables and Kimchi in Yanbian and rice, Kimchi, beverages and fruits in Kuri. Male subjects in Yanbian Consumed alcohol frequently while adults in Kuri consumed coffee more frequently than Yanbian. The major meal patterns were rice+side dish, rice+soup, rice+side dish+Kimchi in Yanbian and rice+soup+side dish+Kimchi, rice+side dish+Kimchi, rice+soup+Kimchi in Kuri. Stir-fried foods, which were consumed 46.6% of all the meals, were dominant side dish in Yanbian, but stir-fried food, seasoned vegetables and grilled food appeared aver 10% in Kuri. There results show that variety of diet of Korean-Chinese in Yanbian was lower than Kuri. Korean-Chinese tend to keep traditional Korean dietary patterns of consuming rice as staple but were adapted to Chinese dietary patterns of consuming stir-fried side dishes. Efforts should be directed toward preserving Korean traditional patterns of dietary culture among Korean-Chinese population.

• Research in Community and Public Health Nursing
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• v.24 no.2
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• pp.151-160
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• 2013

Purpose: This study was to investigate depression in Korean-Chinese elder living in the Yanbian Korean Autonomous Prefecture in China. Methods: A cross-sectional community-based survey was conducted using face to face private interviews for elders aged over 59, who have been dwelling in the Yanbian Korean Autonomous Prefecture. The samples consisted of 183 Korean-Chinese and 182 Han-Chinese with the latter as a reference group. Data were collected from August 25 to September 20, 2011 and analyzed with the SPSS 18.0 program. The GDS (Geriatric Depression Scale) was used to measure elderly depression in the subjects. Results: In Korean-Chinese, the rate of depression was higher in those who had lower educational levels, and were economically supported by the government. And those who had depression showed lower scores in Chinese language proficiency, health status, and social supports, and had more chronic diseases. Factors having effects on Korean-Chinese elderly depression included perceived health status and subjective support. Conclusion: According to the results, for preventing the depression of Korean-Chinese, it is necessary to develop health management programs and social support networks, which were easy to approach.

• Journal of architectural history
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• v.29 no.3
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• pp.15-24
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• 2020

As China enters the 21st century, China is strengthening its position as a world power in an international position. However, there are still problems with Three Agricultural(Agricultural, Rural, Farmer) and unbalanced urban and rural villages. China, as one of the largest and most populous nations, values the development of three farms. Strategies such as "The Construction Of New Socialist Countryside" were a policy to solve rural problems, But they were not enough to achieve breakthrough results. In order to achieve more effective results, the Central Committee of THE STATE COUNCIL proposed The Document No.1 of "Opinion on the Implementation of The Rural Revitalization Strategy" in February 4, 2018 and published "The Rural Revitalization Strategy (2018-2022 )". The Yanbian region, which is the subject of this study, is the home of Korean-Chinese tribes and the Korean autonomous region. As a minority of Chinese ethnic minorities, the Korean-Chinese has their own unique culture, and Yanbian has distinct regional characteristics. As The Rural Revitalization Strategy was raised, Villages is showing positive change in accordance with policy implementation in Yanbian. This study analyzed the current status of policy implementation of The Rural Revitalization Strategy in Yanbian area and analyzed the policy contents and performances based on the of Yanbian Daily News. Based on the results of the analysis, I would like to help in suggesting a more rational development direction and building the villages.

• Journal of Preventive Medicine and Public Health
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• v.31 no.4 s.63
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• pp.828-843
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• 1998

To find the association of perception of health status with lifestyle of different ethnic groups living in north-eastern part of China, a cross-sectional questionnaire survey was done by 10 local health workers for 375 Korean immigrants and 217 Chinese whose age was 30 years old or more. Because Korean immigrants showed higher mortality than Chinese, we expected to find significant lifestyle related with perception of health status which was known to be a predictor of mortality by different ethnic groups. The results were as follows : 1. We found that 59.7% of Yanbian Koreans and 42.9% of Yanbian Chinese felt unhealthy (p=0.000). 2. For Yanbian Koreans, significant variables associated with perception of health status were selected through logistic regression analysis and they were sex; female to male with an OR=2.45 (95% confidence interval[CI] 1.06, 5.64), prevalence of chronic illness with an OR=5.48 (95% CI: 4.62, 15.56), mont of meal; small or moderate to full with an OR=2.67 (95% CI : 1.40, 5.09), preference of spicy food with an OR=1.78 (95% CI : 1.04, 3.04), and less amount intake of vitamin $B_2$, with an OR=2.29 (95% CI : 1.33, 3.93). 3. For Yanbian Chinese, significant variables associated with perception of health status were prevalence of chronic illness with an OR=4.97 (95% CI : 2.11, 11.68), history of taking ginseng with an OR=3.72 (95% CI : 1.33, 10.43), and less intake of vitamin C with an OR=0.18 (95% CI : 0.07, 0.46). In conclusion, sex, presence of chronic illness, dietary habit, and amount of $vitamin-B_1$ intake were associated with perception of health status in Yanbian Koreans. Presence of chronic illness, experience of ginseng intake, and amount of vitamin C intake were associated with perception of health status in Yanbian Chinese. To prove cause-effect relation between perception of health status and lifestyle, further study is needed for these different ethnic groups.