• Title/Summary/Keyword: Y2K

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Inhibition of Pacemaker Activity of Interstitial Cells of Cajal by Hydrogen Peroxide via Activating ATP-sensitive $K^+$ Channels

  • Choi Seok;Parajuli Shankar Prasad;Cheong Hyeon-Sook;Paudyal Dilli Parasad;Yeum Cheol-Ho;Yoon Pyung-Jin;Jun Jae-Yeoul
    • The Korean Journal of Physiology and Pharmacology
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    • v.11 no.1
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    • pp.15-20
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    • 2007
  • To investigate whether hydrogen peroxide($H_2O_2$) affects intestinal motility, pacemaker currents and membrane potential were recorded in cultured interstitial cells of Cajal(ICC) from murine small intestine by using a whole-cell patch clamp. In whole cell patch technique at $30^{\circ}C$, ICC generated spontaneous pacemaker potential under current clamp mode(I=0) and inward currents(pacemaker currents) under voltage clamp mode at a holding potential of -70 mV. When ICC were treated with $H_2O_2$ in ICC, $H_2O_2$ hyperpolarized the membrane potential under currents clamp mode and decreased both the frequency and amplitude of pacemaker currents and increased the resting currents in outward direction under voltage clamp mode. Also, $H_2O_2$ inhibited the pacemaker currents in a dose-dependent manner. Because the properties of $H_2O_2$ action on pacemaker currents were same as the effects of pinacidil(ATP-sensitive $K^+$ channels opener), we tested the effects of glibenclamide(ATP-sensitive $K^+$ channels blocker) on $H_2O_2$ action in ICC, and found that the effects of $H_2O_2$ on pacemaker currents were blocked by co- or pre- treatment of glibenclamide. These results suggest that $H_2O_2$ inhibits pacemaker currents of ICC by activating ATP-sensitive $K^+$ channels.

TWO DIMENSIONAL ARRAYS FOR ALEXANDER POLYNOMIALS OF TORUS KNOTS

  • Song, Hyun-Jong
    • Communications of the Korean Mathematical Society
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    • v.32 no.1
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    • pp.193-200
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    • 2017
  • Given a pair p, q of relative prime positive integers, we have uniquely determined positive integers x, y, u and v such that vx-uy = 1, p = x + y and q = u + v. Using this property, we show that$${\sum\limits_{1{\leq}i{\leq}x,1{\leq}j{\leq}v}}\;{t^{(i-1)q+(j-1)p}\;-\;{\sum\limits_{1{\leq}k{\leq}y,1{\leq}l{\leq}u}}\;t^{1+(k-1)q+(l-1)p}$$ is the Alexander polynomial ${\Delta}_{p,q}(t)$ of a torus knot t(p, q). Hence the number $N_{p,q}$ of non-zero terms of ${\Delta}_{p,q}(t)$ is equal to vx + uy = 2vx - 1. Owing to well known results in knot Floer homology theory, our expanding formula of the Alexander polynomial of a torus knot provides a method of algorithmically determining the total rank of its knot Floer homology or equivalently the complexity of its (1,1)-diagram. In particular we prove (see Corollary 2.8); Let q be a positive integer> 1 and let k be a positive integer. Then we have $$\begin{array}{rccl}(1)&N_{kq}+1,q&=&2k(q-1)+1\\(2)&N_{kq}+q-1,q&=&2(k+1)(q-1)-1\\(3)&N_{kq}+2,q&=&{\frac{1}{2}}k(q^2-1)+q\\(4)&N_{kq}+q-2,q&=&{\frac{1}{2}}(k+1)(q^2-1)-q\end{array}$$ where we further assume q is odd in formula (3) and (4). Consequently we confirm that the complexities of (1,1)-diagrams of torus knots of type t(kq + 2, q) and t(kq + q - 2, q) in [5] agree with $N_{kq+2,q}$ and $N_{kq+q-2,q}$ respectively.

Effect of Flywheel Weight on Engine Performance for the Small Diesel Engine (Flywheel의 중량(重量)이 소형(小型) 디젤기관(機關)의 성능(性能)에 미치는 영향(影響))

  • Jung, Hae Kook;Kim, Sung Rai;Myung, Byung Soo
    • Korean Journal of Agricultural Science
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    • v.15 no.2
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    • pp.143-152
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    • 1988
  • This study was conducted to obtain basic data which affected engine performance of the power tiller being widely used in the rural area. Among the various factors affected engine performance, only flywheel weight was considered as the major factor in this study. Fuel consumption ratio, motoring loss, torque, vibration and mechanical efficiency of the engine tested were measured and analyzed on the four levels of flywheel weight (32.2, 29.7, 26.4, 24.2 kg). The results obtained were as follows: 1. The maximum output of 6 and 7.5 kW engine was 7.43 kW and 7.85 kW respectively. When flywheel weight was reduced from 32.2 kg to 24.2 kg, output power of the engine was increased 0.27 kW in 6 kW engine and increased 0.39 kW in 7.5 kW engine. 2. The fuel consumption ratio was decreased from 300.8 to 296.8 g/kW-hr in 6 kW engine and decreased from 313.6 to 312.8 g/kW-hr in 7.5 kW engine when the flywheel weight was reduced from 32.2 kg to 24.2 kg. 3. The mechanical efficiencies of the engine was increased from 76.1 to 76.8% in 6 kW engine and increased from 76.7 to 77.0% in 7.5 kW engine when the flywheel weight was reduced from 32.2 kg to 24.2 kg. 4. When the flywheel weight was reduced from 32.2 kg to 24.2 kg, a tendency of a little decrease of vibration at X- and Z-axis in 6 kW engine and of a little increase of vibration at Y-axis in 6 kW engine and all directions in 7.5 kW engine was observed. 5. Motoring losses was decreased from 2.33 to l.76 kW in 6 kW engine and decreased from 2.46 to 1.84 kW in 7.5 kW engine when the flywheel weight was reduced from 32.2 kg to 24.2 kg. From the above results and the flywheel weight calculated theoretically, it was recommendable that the flywheel weight should be reduced about 7 kg in 6 kW engine and about 10 kg in 7.5 kW engine, respectively.

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Kinetics and Mechanism of the Reaction of Aquaoxomolybdenum(V) Dimer with Thiocyanate (아쿠아옥소몰리브덴(V) 이합체와 티오시안산이온과의 반응에 대한 속도와 메카니즘)

  • Chang-Su Kim;Joong-Ho Lee
    • Journal of the Korean Chemical Society
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    • v.31 no.4
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    • pp.344-351
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    • 1987
  • Kinetic studies on the complexing of $[Mo_2O_4(H_2O)_6]^{2+}$ with thiocyanate have been carried out using the spectrophotometric method. The observed rate constant is given by, $k_{obsd}=\{\\k_0+k_H[H^+]\}\;[SCN^-]^2+k_r$. At $25^{\circ}C$ and ionic strength of 2.84 the values of $k_f\;and\;k_r\;are\;5.96{\pm}0.35\;M^{-2}s^{-1}\;and\;(5.45{\pm}4.77){\times}10^{-4}s^{-1}$, respectively. Activation parameters from data at $20^{\circ}$$35^{\circ}C\;are\;{\Delta}H^*=38.04{\pm}5.31kJmol^{-1}\;and\;{\Delta}S^*=-172.69JK^{-1}mol^{-1}$. The mechanisms are discussed.

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Hydration in the System of Fluorogypsum-Blast Furnace Slag (불산석고-고로슬래그계의 수화반응)

  • 송종택;고상열;노재성
    • Journal of the Korean Ceramic Society
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    • v.35 no.9
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    • pp.933-938
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    • 1998
  • The hydration for the system of fluorogypsum and 20wt% blast furnace slag was investigated at liquid/soild ratio of 0.45 for 1, 3, and 7 days by using 3 kinds of accelerators such as K2SO4 Al2(SO4)3 $.$16-18H2O and AlK(SO4)2$.$12H2O After curing the hardened specimen was characterized by the compressive strength the content of combined water XRD, DTA and SEM It was found that the activating effect was increased in the order of K2SO4

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Strong Hamiltonicity of Recursive Circulants (재귀원형군의 강한 해밀톤 성질)

  • Park, Jeong-Heum
    • Journal of KIISE:Computer Systems and Theory
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    • v.28 no.8
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    • pp.399-405
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    • 2001
  • 이 논문은 재귀원형군 G(2$^{m}$ , 2$^{k}$ )의 강한 해밀톤 성질을 그래프 이론적 관점에서 고찰한다. 재귀원형군은 [9]에서 제안된 다중 컴퓨터의 연결망 구조이다. G(2$^{m}$ , 2$^{k}$ )가 임의의 정점 쌍 ν, $\omega$를 잇는 길이 ι인 경로를 가지는가 하는 문제를 고려하여, (a) G(2$^{m}$ , 2$^{k}$ )는 ι$\geq$d(ν, $\omega$)을 만족하는 모든 ι에 대해서 길이 ι인 경로를 가지며, (b) G(2$^{m}$ , 4)는 ι$\geq$d(ν, $\omega$)+2인 모든 길이의 경로를 가지며, (c)G(2$^{m}$ , 2$^{k}$ ), k$\geq$3은 길이 d(ν, $\omega$)+2$^{k}$ -3인 경로를 가지지 않는 정점 쌍이 있음을 보인다. 여기서, d(ν, $\omega$)는 ν와 $\omega$ 사이의 거리이다.

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Direct Synthesis of H2O2 over Ti-Containing Molecular Sieves Supported Gold Catalysts: A Comparative Study for In-situ-H2O2-ODS of Fuel

  • Zhang, Han;Liu, Guangliang;Song, Haiyan;Chen, Chunxia;Han, Fuqin;Chen, Ping;Zhao, Zhixi;Hu, Shaozheng
    • Bulletin of the Korean Chemical Society
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    • v.34 no.10
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    • pp.3065-3072
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    • 2013
  • Direct synthesis of $H_2O_2$ and in situ oxidative desulfurization of model fuel over Au/Ti-HMS and Au/TS-1 catalysts has been comparatively investigated in water or methanol. Maximum amount (82%) of active $Au^0$ species for $H_2O_2$ synthesis was obtained. Au/Ti-HMS and Au/TS-1 exhibited the contrary performances in $H_2O_2$ synthesis as $CH_3OH/H_2O$ ratio of solvent changed. $H_2O_2$ decomposition and hydrogenation in water was inhibited by the introduction of methanol. Effect of $O_2/H_2$ ratio on $H_2O_2$ concentration, $H_2$ conversion and $H_2O_2$ selectivity revealed a relationship between $H_2O_2$ generation and $H_2$ consumption. The highest dibenzothiophene removal rate (83.2%) was obtained over Au/Ti-HMS in methanol at 1.5 of $O_2/H_2$ ratio and $60^{\circ}C$. But removal of thiophene over Au/TS-1 should be performed in water without heating to obtain a high removal rate (61.3%). Meanwhile, $H_2$ conversion and oxidative desulfurization selectivity of $H_2$ were presented.

Two-Step Thermochemical Cycle with Supported $NiFe_2O_4$ for Hydrogen Production (지지체의 변화에 따른 Ni-페라이트의 2단계 열화학 사이클 반응 특성에 관한 연구)

  • Kim, Woo-Jin;Kang, Kyoung-Soo;Kim, Chang-Hee;Choi, Won-Chul;Kang, Yong;Park, Chu-Sik
    • Journal of Hydrogen and New Energy
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    • v.19 no.6
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    • pp.505-513
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    • 2008
  • The two-step thermochemical cycle was examined on the $CeO_2$, YSZ, and $ZrO_2$-supported $NiFe_2O_4$ to investigate the effects of support material addition. The supported $NiFe_2O_4$ was prepared by the aerial oxidation method. Thermal reduction was conducted at 1573K and 1523K while water-splitting was carried out at 1073K. Supporting $NiFe_2O_4$ on $CeO_2$, YSZ and $ZrO_2$ alleviated the high-temperature sintering of iron-oxide. As a result, the supported $NiFe_2O_4$ exhibited greater reactivity and repeatability in the water-splitting cycle as compared to the unsupported $NiFe_2O_4$. Especially, $ZrO_2$-supported $NiFe_2O_4$ showed better sintering inhibition effect than other supporting materials, but hydrogen production amount was decreased as cycle repeated. In case of $CeO_2$-supported $NiFe_2O_4$, improvement of hydrogen production was found when the thermal reduction was conducted at 1573K. It was deduced that redox reaction of $CeO_2$ activated above 1573K.

CO Adsorption on Cation Exchaged Zeolite A and Mordenite (陽이온 交煥된 제올라이트 A 및 Mordenite 上의 CO 氣體 吸着)

  • Kim Jong Taik;Kim Heung Won;Kim Myung Chul;Lee Jong Ryul
    • Journal of the Korean Chemical Society
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    • v.36 no.1
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    • pp.137-146
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    • 1992
  • The adsorption properties of CO on the cation exchanged natural zeolite, $K_{111}$ and cation effects upon the CO adsorption were studied. $Na^+-,\;Cu^{2+}-\;and\;Ba^{2+}-\;K_{111}$ exhibited relatively good CO adsorption capacities and $Ba^{2+}- K_{111}$ treated by 0.4 N-$BaCl_2$ solution proved itself as the best adsorbent and superior to the synthetic zeolite 4A and 5A. The observed adsorption tendency due to the cations were in the order of $Ba^{2+}>Cu^{2+}>Na^+>K^+>Mg^{2+}>Ca^{2+}$. The cation exchanged number per unit cell as well as the kind of cation which forms bond with CO molecules in different intensities and other mineral factors such as pore size indicated to be important factors to the CO adsorption properties. The CNDO/2 calculations were performed to compare the adsorption tendencies and CO interaction energy of cations in $K_{111}$.

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