• The Bulletin of The Korean Astronomical Society
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• v.40 no.1
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• pp.75.4-76
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• 2015

우리는 동아시아 각국(대한민국, 중국, 일본)의 VLBI관측망을 통합하고 구성될 동아시아 VLBI 관측망(East Asia VLBI Network; EAVN)의 초기 검증 작업을 진행하고 있다. EAVN은 2 ~ 129 GHz로 관측이 가능하는데, 주로 6.7, 8, 22, 43 GHz로의 관측을 상정하고 있다. 또한 최대 기선장은 약 5,000 km으로 공간분해능은 약 0.3 mas(43 GHz로의 관측의 경우)가 된다. 높은 공간분해능과 고감도의 특징을 활용하고 저광도 활동성은하핵이나 우리 은하의 메이저 천체 등의 연구에 대해서 위력을 나타낼 수가 있다. 우리는 EAVN 시험관측, 상관처리, 자료처리의 실행, 및 그것들을 통한 EAVN 운영의 검증을 하는 EAVN Tiger Team을 2013년에 조직하고 현재까지에 8 GHz 및 22 GHz로 8회의 VLBI 시험관측을 실행하였다. 상관처리는 주로 한국천문연구원에서 운영하고 있는 한일 공동상관기(KJJVC)와 상하이천문대의 소프트웨어 상관기(DiFX)로 실행되어 있다. 현재까지에 8 GHz 및 22 GHz 쌍방에서 프린지검출에 성공하고 있고, 올해는 영상합성을 포함한 과학적인 관측을 진행할 예정이다. 이 발표에서는 EAVN의 개요와 과학목표, 시험관측 현황과 결과, 및 앞으로의 운영 계획 등을 소개하겠다.

• Animal Systematics, Evolution and Diversity
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• v.12 no.3
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• pp.203-210
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• 1996

Four external and 27 cranial characters of Korean field mice (Apodemus peninsulae) from nine regions in China and Korea, representing three subspecies, were analyzed by multivariate methods. Four size-forms were recognized a largest-size form Mt. Weolak and Yeoncheon in Korea (= subspecies peninsulae) and Kirin and Heilung in China (= subspecies praetor), a large-size form from Inner Mongolia in China (= subspecies praetor) and Sanxi and Sandong in China (= subspecies sowerbyi), a middle-size form from Beijing in China (= subspecies sowerbyi), and a small-size form from Xinjiang in China (= subspecies sowerbyi). Although Corbet (1978) recognized only two subspecies in A. peninsulae, subspecies peninsulae and sowerbyi, within its distributional range in the continent of Asia, it was revealed in this study with morphometric characters that A. peninsulae could not be classified simply into two subspecies, because subspecies praetor and subspecies sowerbyi formed the large-size form and because subspecies sowerbyi was so diverse in its morphology as to be composed of three size-forms. Further analyses with the samples from other regions of China and Russia seem to be necessary to clarify the taxonomy of A. peninsulae.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2903-2908
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• 2012

Background: Matrix metalloproteinase-9 (MMP-9) is associated with disruption of basement membranes of blood vessels and promotion of metastasis through the lymphatics. However, its prognostic value for survival in patients with gastric cancer remains controversial. Method: We therefore conducted a meta-analysis of the published literature in order to clarify the impact of MMP-9. Clinical studies were selected for further analysis if they provided an independent assessment of MMP-9 in gastric cancer and reported analysis of survival data according to MMP-9 expression. Results: A total of 11 studies, covering 1700 patients, were included for meta-analysis. A summary hazard ratio (HR) of all studies and sub-group hazard ratios were calculated. The combined HR suggested that a positive MMP-9 expression had an impact on overall survival: 1.25 (95% confidence interval 1.11-1.40) in all eligible studies; 1.13 (1.06-1.20) in 8 studies detecting MMP-9 by immunohistochemistry; 1.36 (1.12-1.65) in 7 studies from Asia. Only one study for DFS showed a significant impact on disease free survival (HR 1.73, 95%CI 1.27-2.34). Conclusions: Our findings suggested that MMP-9 protein expression might be a factor for a poor prognosis in patients with gastric cancer. However, the association was rather weak, so that more prospective studies should further explore the prognostic impact of MMP-9 mRNA and correlations between MMP-9 and clinicopathological characteristics.

• Journal of the Optical Society of Korea
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• v.20 no.2
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• pp.269-275
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• 2016

This study has investigated the feasibility of 980-nm low-energy pulsed near-infrared laser stimulation to evoke auditory responses, as well as the effects of radiant exposure and pulse duration on auditory responses. In the experiments, a hole was drilled in the basal turn of the cochlea in guinea pigs. An optical fiber with a 980-nm pulsed infrared laser was inserted into the hole, orientating the spiral ganglion cells in the cochlea. To model deafness, the tympanic membrane was mechanically damaged. Acoustically evoked compound action potentials (ACAPs) were recorded before and after deafness, and optically evoked compound action potentials (OCAPs) were recorded after deafness. Similar spatial selectivity between optical and acoustical stimulation was found. In addition, OCAP amplitudes increased with radiant exposure, indicating a photothermal mechanism induced by optical stimulation. Furthermore, at a fixed radiant exposure, OCAP amplitudes decreased as pulse duration increased, suggesting that optical stimulation might be governed by the time duration over which the energy is delivered. Thus, the current experiments have demonstrated that a 980-nm pulsed near-infrared laser with low energy can evoke auditory neural responses similar to those evoked by acoustical stimulation. This approach could be used to develop optical cochlear implants.

• Bulletin of the Korean Chemical Society
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• v.32 no.8
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• pp.2537-2543
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• 2011

A self-assembled Al-bridged diiminopyridine-based ligand (3) was synthesized and characterized by FT-IR, ESI-MS and NMR spectroscopy. Electron spectral titrations were performed to confirm the formation of a novel trinuclear bis(imino)pyridyl iron(II) complex (4) upon addition of $FeCl_2$ into Al-bridged ligand 3 in methanol solution. Simultaneously, a typical bis(imino)pyridine-iron(II) complex (2) was synthesized and fully characterized. The X-ray crystal study of the iron(II) complex 2 disclosed a five-coordinate, distorted square-pyramidal structure with the tridentate N^N^N ligand and chlorides. The optimal molecular structure of 4 was obtained by means of molecular mechanics, which showed that each iron atom in the complex 4 is surrounded by two chlorides, a tridentate N^N^N ligand and one oxygen atom, supporting considerations about the possibility of six-coordinate geometry from MMAO or the ethylene access. A comparison of 4 with the reference 2 revealed a remarkable decrease of the catalytic activity and MMAO consumption (activity up to $0.41{\times}10^3\;kg\;{mol_{Fe}}^{-1}h^{-1}bar^{-1}$, Al/Fe = 650 for 4 and $7.02{\times}10^3\;kg\;{mol_{Fe}}^{-1}h^{-1}bar^{-1}$, Al/Fe = 1600 for 2).

• Current Optics and Photonics
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• v.1 no.3
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• pp.196-202
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• 2017

Corona discharge is always a sign of failure processes of high-voltage electrical apparatus, including those utilized in electric railway systems. Solar-blind ultraviolet (UV) cameras are effective tools for corona inspection. In this work, we present an automatic railway corona-discharge detection system based on solar-blind ultraviolet detection. The UV camera, mounted on top of a train, inspects the electrical apparatus, including transmission lines and insulators, along the railway during fast cruising of the train. An algorithm based on the Hough transform is proposed for distinguishing the emitting objects (corona discharge) from the noise. The detection system can report the suspected corona discharge in real time during fast cruises. An experiment was carried out during a routine inspection of railway apparatus in Xinjiang Province, China. Several corona-discharge points were found along the railway. The false-alarm rate was controlled to less than one time per hour during this inspection.

• Asian-Australasian Journal of Animal Sciences
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• v.25 no.4
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• pp.471-478
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• 2012

The role of moisture absorptive capacity of pre-silage material and its relationship with silage effluent in high moisture by-product feedstuffs (HMBF) is assessed. The term water retention capacity which is sometimes used in explaining the rate of effluent control in ensilage may be inadequate, since it accounts exclusively for the capacity of an absorbent incorporated into a pre-silage material prior to ensiling, without consideration to how much the pre-silage material can release. A new terminology, 'potential water retention capacity' (PWRC), which attempts to address this shortcoming, is proposed. Data were pooled from a series of experiments conducted separately over a period of five years using laboratory silos with four categories of agro by-products (n = 27) with differing moisture contents (highest 96.9%, lowest 78.1% in fresh matter, respectively), and their silages (n = 81). These were from a vegetable source (Daikon, Raphanus sativus), a root tuber source (potato pulp), a fruit source (apple pomace) and a cereal source (brewer's grain), respectively. The pre-silage materials were adjusted with dry in-silo absorbents consisting wheat straw, wheat or rice bran, beet pulp and bean stalks. The pooled mean for the moisture contents of all pre-silage materials was 78.3% (${\pm}10.3$). Silage effluent decreased (p<0.01), with increase in PWRC of pre-silage material. The theoretical moisture content and PWRC of pre-silage material necessary to stem effluent flow completely in HMBF silage was 69.1% and 82.9 g/100 g in fresh matter, respectively. The high correlation (r = 0.76) between PWRC of ensiled material and silage effluent indicated that the latter is an important factor in silage-effluent relationship.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.11
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• pp.5476-5496
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• 2016

Energy efficiency of resource-constrained wireless sensor networks is critical in applications such as real-time monitoring/surveillance. To improve the energy efficiency and reduce the energy consumption, the time series data can be compressed before transmission. However, most of the compression algorithms for time series data were developed only for single variate scenarios, while in practice there are often multiple sensor nodes in one application and the collected data is actually multivariate time series. In this paper, we propose to compress the time series data by the Lasso (least absolute shrinkage and selection operator) approximation. We show that, our approach can be naturally extended for compressing the multivariate time series data. Our extension is novel since it constructs an optimal projection of the original multivariates where the best energy efficiency can be realized. The two algorithms are named by ULasso (Univariate Lasso) and MLasso (Multivariate Lasso), for which we also provide practical guidance for parameter selection. Finally, empirically evaluation is implemented with several publicly available real-world data sets from different application domains. We quantify the algorithm performance by measuring the approximation error, compression ratio, and computation complexity. The results show that ULasso and MLasso are superior to or at least equivalent to compression performance of LTC and PLAMlis. Particularly, MLasso can significantly reduce the smooth multivariate time series data, without breaking the major trends and important changes of the sensor network system.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.1
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• pp.58.3-59
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• 2016

동아시아 VLBI 관측망(the East-Asian VLBI Network; EAVN)은 한 중 일 각국의 전파망원경을 통합해서 구성되는 동아시아 지역의 새로운 VLBI 관측망이다. EAVN의 주된 관측주파수는 6.7, 8, 22, 43 GHz이고 최고 공간분해능은 약 0.6 mas이다. 우리는 EAVN의 성능검증을 목적으로 하는 국제연구팀을 구성하고 2013년부터 2015년까지 주로 8, 22 GHz로의 프린지검출 시험관측을 실행해왔다. 이들의 결과에 의거해서 작년말부터 앞으로의 EAVN 어레이 공개를 목표로 할 영상합성 시험관측을 시작하였다. 첫 번째 시험관측은 한 중 일 9개의 안테나를 이용해서 2015년12월13일에 8 GHz로 실시하였다, 관측 천체는 밝은 활동성 은하핵인 4C 39.25이고, 국제간 기선에서 성공적으로 프린지를 검출하였다. 우리는 올해부터 100 시간 이상을 이용해서 상기 네 주파수로의 영상합성 시험관측을 실시할 계획이고, 2017년 후반기부터 부분적인 공개관측을 시작할 예정이다. 이 발표에서는 주로 EAVN의 현황과 상기 영상합성 시험관측의 결과에 관해서 보고한다.

• Biomolecules & Therapeutics
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• v.25 no.3
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• pp.272-278
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• 2017

Fucoidan has been reported to exhibit various beneficial activities ranging from to antivirus and anticancer properties. However, little information is available about the effects of fucoidan on cerebral ischemia-reperfusion injury (IRI). Our study aimed to explore the effects of fucoidan on cerebral IRI, as well as the underlying mechanisms. Sprague-Dawley (SD) rats were randomly subjected to four groups: Sham, IRI+saline (IRI+S), IRI+80 mg/kg fucoidan (IRI+F80), and IRI+160 mg/kg fucoidan (IRI+F160). Fucoidan (80 mg/kg or 160 mg/kg) was intraperitoneally injected from 7 days before the rats were induced to cerebral IRI model with middle cerebral artery occlusion (MCAO) method. At 24 h after reperfusion, neurological deficits and the total infarct volume were determined. The levels of inflammation-associated cytokines (interleukin (IL)-$1{\beta}$, IL-6, myeloperoxidase (MPO), and tumor necrosis factor (TNF)-${\alpha}$), oxidative stress-related proteins (malondialdehyde (MDA) and superoxide dismutase (SOD)) in the ischemic brain were measured by enzyme-linked immunosorbent assay (ELISA). Besides, the levels of apoptosis-related proteins (p-53, Bax, and B-cell lymphoma (Bcl)-2) and mitogen-activated protein kinase (MAPK) pathway (phosphorylation-extracellular signal-regulated kinase (p-ERK), p-c-Jun N-terminal kinase (JNK), and p-p38) were measured. Results showed that administration of fucoidan significantly reduced the neurological deficits and infarct volume compared to the IRI+S group in a dose-dependent manner. Also, fucoidan statistically decreased the levels of inflammation-associated cytokines, and oxidative stress-related proteins, inhibited apoptosis, and suppressed the MAPK pathway. So, Fucoidan plays a protective role in cerebral IRI might be by inhibition of MAPK pathway.