• Biomolecules & Therapeutics
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• 제25권3호
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• pp.231-238
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• 2017

Myelin is a specialized structure of the nervous system that both enhances electrical conductance and insulates neurons from external risk factors. In the central nervous system, polarized oligodendrocytes form myelin by wrapping processes in a spiral pattern around neuronal axons through myelin-related gene regulation. Since these events occur at a distance from the cell body, post-transcriptional control of gene expression has strategic advantage to fine-tune the overall regulation of protein contents in situ. Therefore, many research interests have been focused to identify RNA binding proteins and their regulatory mechanism in myelinating compartments. Fragile X mental retardation protein (FMRP) is one such RNA binding protein, regulating its target expression by translational control. Although the majority of works on FMRP have been performed in neurons, it is also found in the developing or mature glial cells including oligodendrocytes, where its function is not well understood. Here, we will review evidences suggesting abnormal translational regulation of myelin proteins with accompanying white matter problem and neurological deficits in fragile X syndrome, which can have wider mechanistic and pathological implication in many other neurological and psychiatric disorders.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2008년도 한국우주과학회보 제17권1호
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• pp.24.3-24.3
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• 2008

• Journal of Astronomy and Space Sciences
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• 제33권3호
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• pp.173-176
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• 2016

We report on a systematic analysis of the spin and superorbital modulations of the high-mass X-ray binary 4U 0114+650, which consists of the slowest spinning neutron star known. Utilizing dynamic power spectra, we found that the spin period varied dramatically during the RXTE ASM and Swift BAT observations. This variation consists of a long-term spin-up trend, and two ~1,000 day and one ~600 day random walk epochs previously, MJD 51,000, ~MJD 51,400-52,000, and ~MJD 55,100-56,100. We further found that the events appear together with depressions of superorbital modulation amplitude. This provides evidence of the existence of an accretion disk, although the physical mechanism of superorbital modulation remains unclear. Furthermore, the decrease of the superorbital modulation amplitude may be associated with the decrease of mass accretion rate from the disk, and may distribute the accretion torque of the neutron star randomly in time.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제10권6호
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• pp.243-250
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• 2021

최근 VR/AR/MR 기술과 3D 주변 장치의 발전에 의해 3D 가상현실 응용 서비스 개발이 증가하고 있으며 이에 따라 3D 데이터의 호환성과 이식성에 대한 요구가 증가하고 있다. 여러 장치의 응용 프로그램의 데이터를 공동으로 사용할 수 있도록 하기 위해서는 3D 표준 데이터 형식의 파일 처리가 요구된다. 이 때 가상환경 장면 처리에 필요한 공통의 파일 형식과 함께 함수와 변수 클래스들을 표준화된 라이브러리와 데이터구조를 제공한다면 응용 별로 서로 다른 파일 형식과 데이터구조의 사용으로 인해 발생하는 불필요한 처리 과정을 생략할 수 있어서 보다 효율적인 시스템 구성이 가능할 것이다. 본 연구에서는 이러한 공통의 데이터 파일과 데이터구조 사용 기능을 위해서 특정의 프로그래밍 언어를 이용하여 공용의 3D 표준 파일에 접근하여 다양한 서비스를 개발할 수 있도록 표준화된 데이터를 생성하고 저장할 수 있는 프로그래밍 바인딩 도구를 제공하는 것이 목적이다. 이를 위해 본 논문에서는 Python 프로그래밍 언어를 이용하여 X3D 파일을 표준화된 방식으로 접근할 수 있도록 클래스와 함수를 포함하는 공통의 데이터구조를 정의하며 이 언어 바인딩 인터페이스를 기반으로 X3D 장면 데이터 파일을 렌더링 하는 X3D VR 뷰어인 Python 언어 바인딩 뷰어 구현에 대해 기술한다. 이 뷰어는 X3D 오브젝트의 생성, 변경, 교환 및 전송을 위한 Python 기반의 3D 장면 라이브러리들과 데이터구조를 포함한다. 그리고 이를 이용하여 X3D 오브젝트를 디스플레이하고 이벤트들을 처리한다.

• 한국심리학회지 : 문화 및 사회문제
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• 제26권3호
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• pp.195-220
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• 2020

본 연구는 외상 후 성장의 정도를 측정하는 외상 후 성장 척도의 확장판(The Posttraumatic Growth Inventory-X: PTGI-X)을 국내에 타당화하고자 하였다. PTGI-X 척도는 기존 PTGI의 '영적·종교적 관심의 증가 요인'에 대한 보완의 필요성에 따라 실존적 깊이 증가를 측정하는 문항이 추가된 척도이다. 이를 위해 외상 경험이 있는 성인 625명을 대상으로 K-PTGI-X의 요인구조를 확인하고, 타당도와 신뢰도를 검증하였다. 먼저, 탐색적 요인분석을 통해 외상을 경험한 국내 성인을 대상으로 적절한 PTGI-X의 요인구조를 확인하였고, 4요인 구조가 가장 적절한 것으로 나타났다. 다음으로, 확인적 요인분석을 실시한 결과 4요인 모형에 문항 간 상관을 추가한 모형이 모형적합도가 좋은 것으로 나타났다. 내적 신뢰도, 분산추출지수, 개념 신뢰도를 검토하여 문항들이 요인을 구성하는 데에 문제가 없으며 신뢰로운 도구임을 확인하였다. 타당도를 확인하기 위해 관련성이 높은 것으로 알려진 핵심신념붕괴, 의도적 반추와의 유의한 상관관계를 확인하여 동시 타당도를 검증하였고, 침습적 반추와 통계적으로 유의하지 않은 관계를 확인하여 변별 타당도를 검증하였다. 마지막으로 K-PTGI-X의 이해를 더하기 위해 인구통계학적 변인에 따른 차이분석을 실시하였다. 연구결과를 바탕으로 본 연구의 논의와 시사점을 제시하였다.

• 천문학회지
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• 제40권4호
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• pp.99-106
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• 2007

Statistical analyses were performed to investigate the relative success and accuracy of daily maximum X-ray flux (MXF) predictions, using both multilinear regression and autoregressive time-series prediction methods. As input data for this work, we used 14 solar activity parameters recorded over the prior 2 year period (1989-1990) during the solar maximum of cycle 22. We applied the multilinear regression method to the following three groups: all 14 variables (G1), the 2 so-called 'cause' variables (sunspot complexity and sunspot group area) showing the highest correlations with MXF (G2), and the 2 'effect' variables (previous day MXF and the number of flares stronger than C4 class) showing the highest correlations with MXF (G3). For the advanced three days forecast, we applied the autoregressive timeseries method to the MXF data (GT). We compared the statistical results of these groups for 1991 data, using several statistical measures obtained from a $2{\times}2$ contingency table for forecasted versus observed events. As a result, we found that the statistical results of G1 and G3 are nearly the same each other and the 'effect' variables (G3) are more reliable predictors than the 'cause' variables. It is also found that while the statistical results of GT are a little worse than those of G1 for relatively weak flares, they are comparable to each other for strong flares. In general, all statistical measures show good predictions from all groups, provided that the flares are weaker than about M5 class; stronger flares rapidly become difficult to predict well, which is probably due to statistical inaccuracies arising from their rarity. Our statistical results of all flares except for the X-class flares were confirmed by Yates' $X^2$ statistical significance tests, at the 99% confidence level. Based on our model testing, we recommend a practical strategy for solar X-ray flare predictions.

• 한국대기환경학회지
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• 제26권2호
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• pp.161-176
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• 2010

We examined high ozone episodes observed during the intensive measurement periods (11 May~21 June and 30 July~11 August 2009) in the Gulf of Gwangyang. During that period, there were a few events (or days) in which 1 hr averaged ozone concentrations were greater than 100 ppbv. The analysis of ozone budget and photochemical characteristics related to the ozone production was carried out using a photochemical box model. Ozone sensitivity to $NO_x$ and VOCs was also examined in the study area during the measurement period. Diurnal variation of ozone during the episodes was similar to that of odd hydrogen radicals ($HO_2,CH_3O_2$, and $RO_2$), suggesting significant correlation with photochemical production of ozone during the episodes. In general, ozone concentration in the study area during the measurement period was sensitive to VOCs, whereas ozone was sensitive to $NO_x$ under certain conditions. Ozone sensitivity assessment using a radical budget analysis and $NO_x$/VOCs-control strategy was consistent with that using indicator species ($H_2O_2/HNO_3$ ratio).

• 우주기술과 응용
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• 제3권1호
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• pp.1-25
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• 2023

In this paper, I briefly introduce recently terminated, current, and future scientific spacecraft missions for in situ and remote-sensing observations of Earth's and other planetary magnetospheres as of February 2023. The spacecraft introduced here are Geotail, Cluster, Time History of Events and Macroscale Interactions during Substorms / Acceleration, Reconnection, Turbulence, and Electrodynamics of the Moon's Interaction with the Sun (THEMIS / ARTEMIS), Magnetospheric Multiscale (MMS), Exploration of energization and Radiation in Geospace (ERG), Cusp Plasma Imaging Detector (CuPID), and EQUilibriUm Lunar-Earth point 6U Spacecraft (EQUULEUS) for recently terminated or currently operated missions for Earth's magnetosphere; Lunar Environment Heliospheric X-ray Imager (LEXI), Gateway, Solar wind Magneto-sphere Ionosphere Link Explorer (SMILE), HelioSwarm, Solar-Terrestrial Observer for the Response of the Magnetosphere (STORM), Geostationary Transfer Orbit Satellite (GTOSat), GEOspace X-ray imager (GEO-X), Plasma Observatory, Magnetospheric Constellation (MagCon), self-Adaptive Magnetic reconnection Explorer (AME), and COnstellation of Radiation BElt Survey (CORBES) approved for launch or proposed for future missions for Earth's magnetosphere; BepiColombo for Mercury and Juno for Jupiter for current missions for planetary magnetospheres; Jupiter Icy Moons Explorer (JUICE) and Europa Clipper for Jupiter, Uranus Orbiter and Probe (UOP) for Uranus, and Neptune Odyssey for Neptune approved for launch or proposed for future missions for planetary magnetospheres. I discuss the recent trend and future direction of spacecraft missions as well as remaining challenges in magnetospheric research. I hope this paper will be a handy guide to the current status and trend of magnetospheric missions.

• International Journal of Concrete Structures and Materials
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• 제10권sup3호
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• pp.87-96
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• 2016

This numerical study investigated the effects of different reinforcing details in beam-column joints on the blast resistance of the joints. Due to increasing manmade and/or natural high rate accidents such as impacts and blasts, the resistance of critical civil and military infrastructure or buildings should be sufficiently obtained under those high rate catastrophic loads. The beam-column joint in buildings is one of critical parts influencing on the resistance of those buildings under extreme events such as earthquakes, impacts and blasts. Thus, the details of reinforcements in the joints should be well designed for enhancing the resistance of the joints under the events. Parameters numerically investigated in this study include diagonal, flexural, and shear reinforcing steel bars. The failure mechanism of the joints could be controlled by the level of tensile stress of reinforcing steel bars. Among various reinforcing details in the joints, diagonal reinforcement in the joints was found to be most effective for enhancing the resistance under blast loads. In addition, shear reinforcements also produced favourable effects on the blast resistance of beam-column joints.

• 천문학회보
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• 제43권1호
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• pp.56.1-56.1
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• 2018

Tidal disruption events (TDEs) provide evidence for quiescent supermassive black holes (SMBHs) in the centers of inactive galaxies. TDEs occur when a star on a parabolic orbit approaches close enough to a SMBH to be disrupted by the tidal force of the SMBH. The subsequent super-Eddington accretion of stellar debris falling back to the SMBH produces a characteristic flare lasting several months. The theoretically expected bolometric light curve decays with time as proportional to $t^{-5/3}$. However, the light curves observed in most of the optical-UV TDEs deviate from the $t^{-5/3}$ decay rate especially at early time, while the light curves of some soft-X-ray TDEs are overall in good agreement with the $t^{-5/3}$ law. Therefore, it is required to construct the theoretical model for explaining these light curve variations consistently. In this paper, we revisit the mass fallback rates analytically and semi-analytically by taking account of the structure of the star, which is simply modeled by the polytrope. We find the relation between a polytropic index and the power law index of the mass fallback rate. We also discuss whether and how the decay curves, which we derived, fit the observed ones.