• Journal of Astronomy and Space Sciences
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• 제30권2호
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• pp.83-85
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• 2013

Anomalous X-ray pulsars (AXPs) are thought to be magnetars which are young isolated neutron stars with extremely strong magnetic fields of > $10^{14}$ Gauss. Their tremendous magnetic fields inferred from the spin parameters provide a huge energy reservoir to power the observed X-ray emission. High-energy emission above 0.3 MeV has never been detected despite intensive search. Here, we present the possible Fermi Large Area Telescope (LAT) detection of ${\gamma}$-ray pulsations above 200 MeV from the AXP, 1E 2259+586, which puts the current theoretical models of ${\gamma}$-ray emission mechanisms of magnetars into challenge. We speculate that the high-energy ${\gamma}$-rays originate from the outer magnetosphere of the magnetar.

• 한국어류학회지
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• 제21권sup1호
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• pp.63-72
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• 2009

The taxonomic research based on extensive investigations and specimen collections throughout all varieties of freshwater and marine habitats of Chinese waters, including mainland China, Hong Kong and Taiwan, which involved accounting the vast number of collected specimens, data and literature (both within and outside China) were carried out over the last 40 years. There are totally 361 recorded species of gobioid fishes belonging to 113 genera, 5 subfamilies, and 9 families. This gobioid fauna of China comprises 16.2% of 2211 known living gobioid species of the world. This report represents a summary of previous researches on the suborder Gobioidei. A recently diagnosed subfamily, Polyspondylogobiinae, were assigned from the type genus and type species: Polyspondylogobius sinensis Kimura & Wu, 1994 which collected around the Pearl River Delta with high extremity of vertebral count up to 52-54. The undated comprehensive checklist of gobioid fishes in China will be provided in this paper.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2008년도 Asian Magnetics Conference
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• pp.157.2-157.2
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• 2008

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2008년도 Asian Magnetics Conference
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• pp.158.1-158.1
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• 2008

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2008년도 Asian Magnetics Conference
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• pp.111.1-111.1
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• 2008

• Journal of Ginseng Research
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• 제46권3호
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• pp.418-425
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• 2022

Background: Sorafenib is effective in treating hepatoma, but most patients develop resistance to it. STAT3 signaling has been implicated in sorafenib resistance. Artesunate (ART) and 20(R)-ginsenoside Rg3 (Rg3) have anti-hepatoma effects and can inhibit STAT3 signaling in cancer cells. This study aimed to evaluate the effects of Rg3 in combination with ART (Rg3-plus-ART) in overcoming sorafenib resistance, and to examine the involvement of STAT3 signaling in these effects. Methods: Sorafenib-resistant HepG2 cells (HepG2-SR) were used to evaluate the in vitro anti-hepatoma effects of Rg3-plus-ART. A HepG2-SR hepatoma-bearing BALB/c-nu/nu mouse model was used to assess the in vivo anti-hepatoma effects of Rg3-plus-ART. CCK-8 assays and Annexin V-FITC/PI double staining were used to examine cell proliferation and apoptosis, respectively. Immunoblotting was employed to examine protein levels. ROS generation was examined by measuring DCF-DA fluorescence. Results: Rg3-plus-ART synergistically reduced viability of, and evoked apoptosis in HepG2-SR cells, and suppressed HepG2-SR tumor growth in mice. Mechanistic studies revealed that Rg3-plus-ART inhibited activation/phosphorylation of Src and STAT3 in HepG2-SR cultures and tumors. The combination also decreased the STAT3 nuclear level and induced ROS production in HepG2-SR cultures. Furthermore, overactivation of STAT3 or removal of ROS diminished the anti-proliferative effects of Rg3-plus-ART, and removal of ROS diminished Rg3-plus-ART's inhibitory effects on STAT3 activation in HepG2-SR cells. Conclusions: Rg3-plus-ART overcomes sorafenib resistance in experimental models, and inhibition of Src/STAT3 signaling and modulation of ROS/STAT3 signaling contribute to the underlying mechanisms. This study provides a pharmacological basis for developing Rg3-plus-ART into a novel modality for treating sorafenib-resistant hepatoma.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2006년도 International Symposium on GPS/GNSS Vol.1
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• pp.247-250
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• 2006

Integrating a GPS based vehicle navigation system and the latest optimal algorithms, this research aims to develop a real-time decision support platform for concrete plant to provide the optimal solutions for ready mixed concrete delivery. The platform includes fleet tracking system, simulation and optimization tools, and visual interface which is useful to monitor delivery progress, to obtain crucial historical and real-time data for simulation, and to improve the efficiency of the plant operation. This paper presents configuration of the system and performance evaluation based on operational data.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2005년도 학술발표회(1)
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• pp.817-817
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• 2005

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2003년도 The Fifth Asian Computational Fluid Dynamics Conference
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• pp.29-32
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• 2003

It is shown that using the unified coordiantes of Hui et al.[1 - 4], one can now compute fluid flow without prior grid generation. This represents a great saving of computing time.

• 지역과문화
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• 제7권4호
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• pp.69-81
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• 2020

随着互联网公司进军电影产业, 中国的IP电影迅速发展, 并给电影市场带来巨大的商业利益。通过互联网数据, 新媒体等技术, 改变电影制作, 营销和收益模式, 形成新的产业链。本论文试图诊断中国IP电影热潮的现象, 并得出其意义和启示。为此, 选出了不同类型的代表事例来研究存在的问题和相应的改善方案。事例选定了现在IP电影改编中最受瞩目的小说, 漫画, 音乐等3个类型中的代表性作品《悟空传》, 《快把我哥带走》, 《同桌的你》。研究结果显示, 中国的IP电影存在统一化严重, 剧本创作能力不足, 版权等问题。为此, 提出了构建IP版权交易平台, 加强IP创作, 推进IP产业价值链等改善方案。希望通过这项研究进一步完善和推动中国IP电影市场的发展, 打造属于中国IP电影的价值链品牌。