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Usefulness of FDG-PET/CT as a Diagnostic Tool for Routine Post Therapy Evaluation in Endometrial Cancer (자궁내막암의 치료 후 루틴 추적검사 방법으로서 FDG-PET/CT의 유용성)

  • Lee, Shin-Jae;Jeon, Tae-Joo;Kim, Seung-Jo;Kim, Hee-Jin;An, Hee-Jung
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.4
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    • pp.301-308
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    • 2009
  • Purpose: The aim of this study was to evaluate the usefulness of FDG-PET/CT as follow up imaging tool in patients with endometrial cancer after therapy. Material and Methods: One hundred one patients with endometrial cancer who underwent FDG PET/CT after the treatment of this disease were included in this study population (25-79 yr old, Mean age 50.6 yr old) and all these patients also performed various laboratory and imaging studies such as serum tumor marker, CT or MRI. The lesions having increased focal FDG uptake were classified into benign, equivocal, and malignant one according to their pattern and activity. Tumor recurrence was confirmed by histopathological results and other clinical and imaging data. Results: Among the 19 patients with 30 malignant or equivocal hot uptakes, 11 of 14 patients supposed to be malignant finding in PET/CT were proved to be tumor recurrence, while one of 5 patients with equivocal lesions were recurred malignancy, Two false negative cases were turned out to be peritoneal carcinomatosis, Estimated sensitivity, specificity and accuracy of PET/CT for diagnosis of recurrence in endometrial carcinoma after treatment were 86 %, 92 % and 91 %, respectively. Positive and negative predictive values in the same issue were 63% and 98%, respectively. Conclusion: FDG-PET/CT is useful for regular work up of endometrial carcinoma after the treatment because of its high negative predictive value as well as high sensitivity and specificity.

Unsteady RANS computations of turbulent flow in a high-amplitude meandering channel (고진폭 만곡수로에서 난류흐름의 비정상 RANS 수치모의)

  • Lee, Seungkyu;Paik, Joongcheol
    • Journal of Korea Water Resources Association
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    • v.50 no.2
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    • pp.89-97
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    • 2017
  • Turbulent flow structure in the high amplitude meandering channel is complex due to secondary recirculation with helicoidal motions and shear layers formed by flow separation from the curved sidewall. In this work, the secondary flow and the superelevation of the water surface produced in the high-amplitude Kinoshita channel are reproduced by the unsteady Reynolds-averaged Navier-Stokes (RANS) computations using the VOF technique for resolving the variation of water surface elevation and three statistical turbulence models ($k-{\varepsilon}$, RNG $k-{\varepsilon}$, $k-{\omega}$ SST). The numerical results computed by a second-order accurate finite volume method are compared with an existing experimental measurement. Among applied turbulence models, $k-{\omega}$ SST model relatively well predicts overall distribution of the secondary recirculation in the Kinoshita channel, while all three models yield similar prediction of water superelevation transverse slope. The secondary recirculation driven by the radial acceleration in the upstream bend affects the flow structure in the downstream bend, which yields a pair of counter-rotating vortices at the bend apex. This complex flow pattern is reasonably well reproduced by the $k-{\omega}$ SST model. Both $k-{\varepsilon}$ based models fail to predict the clockwise-rotating vortex between a pair of counter-rotating vortices which was observed in the experiment. Regardless of applied turbulence models, the present computations using the VOF method appear to well reproduce the superelevation of water surface through the meandering channel.

Characteristics and breeding of a new cultivar Pleurotus eryngii, Seolsong (큰느타리버섯 신품종 '설송'의 육성 및 그 특성)

  • Shin, Pyung-Gyun;Yoo, Young-Bok;Kong, Won-Sik;Jang, Kab-Yeul;Oh, Youn-Lee;Cheong, Jong-Chun
    • Journal of Mushroom
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    • v.11 no.2
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    • pp.77-81
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    • 2013
  • To develop a new cultivar of king oyster mushroom(Pleurotus eryngii), G09-21 as parental strain was selected by the method of Di-mon crossing between monokaryotic strain ASI 2824-21 derived from ASI 2824(Keunneutari No. 2) and dikaryotic strain ASI 2887(Aeryni 3). The Pe21-53(G09-21-10 x ASI 2844-9) was shown the best cultural characteristics, selected to be a new cultivar and designated as 'Seolsong'. The 'Seolsong' was distinctly formed incompatibility line in the confrontation growth of parental strains Keunneutari No. 2, Aeryni 3 and ASI 2844. Analysis of the genetic characteristics of the new cultivar 'Seolsong' showed a different DNA profile as that of the control strains, Keunneutari No. 2, Aeryni 3 and ASI 2844, when RAPD(Random Amplified Polymorphic DNA) primer URP4 was used. The optimum temperature and pH arrange for mycelial growth were $25{\sim}30^{\circ}C$ and pH 5~8, respectively. This new cultivar 'Seolsong' of fruiting body production per bottle was about $131.4{{\pm}}43.1$ g which is about 102% quantity compared to that of other cultivar Keunneutari No. 2. And also the stipe is thick and long, but the number of available stipe is few. Particularly, it was tolerant of high moisture above 90% during the growth period after primodia formation. We therefore expect that this new strain will save of labor and cost of cultivation by without culling work.

On the Change of Hydrologic Conditions due to Global Warming : 1. An Analysis on the Change of Temperature in Korea Peninsula using Regional Scale Model (지구온난화에 따른 수문환경의 변화와 관련하여 : 1. 국지규모 모형을 이용한 한반도 기온의 변화 분석)

  • An, Jae-Hyeon;Yun, Yong-Nam;Lee, Jae-Su
    • Journal of Korea Water Resources Association
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    • v.34 no.4
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    • pp.347-356
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    • 2001
  • Even though the increase of greenhouse gases such as $CO_2$ is thought to be the main cause for global warming, its impact on global climate has not been revealed clearly in rather quantitative manners. However, researches using Genral Circulation Model(GCM) has shown that the accumulation of greenhouse gases increases the global mean temperature, which in turn impacts on the global water circulation pattern. A climate predictive capability is limited by lack of understanding of the different process governing the climate and hydrologic systems. The prediction of the complex responses of the fully coupled climate and hydrologic systems can be achieved only through development of models that adequately describe the relevant process at a wide range of spatial and temporal scales. These models must ultimately couple the atmospheres, oceans, and lad and will involve many submodels that properly represent the individual processes at work within the coupled components of systems. So far, there are no climate and related hydrologic models except local rainfall-runoff models in Korea. The purpose of this research is to predict the change of temperature in Korean Peninsula using regional scale model(IRSHAM96 model) and GCM data obtained from the increasing scenarios of $CO_2$ Korean Peninsula increased by $2.5^{\circ}C$ and the duration of Winter in $lxCO_2$ condition would be shorter the $2xCo_2$ condition due to global warming.

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Immunofluorescence and Electron Microscopic Study on the Artificial Insemination and Rotation-Shift Behaviors of the Bipolar Spindle Fiber in U. unicinctus Egg (U. unicinctus 난자의 인공수정과 감수분열 장치의 회전-이동행위에 관한 면역형광현미경 및 전자현미경적 연구)

  • Kwon, Hyuk-Jae;Jeong, Jin-Wook;Kim, Wan-Jong;Shin, Kil-Sang
    • Applied Microscopy
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    • v.33 no.2
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    • pp.105-116
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    • 2003
  • In Vitro fertilization of U. unicinctus eggs observed by immunofluorescence and electron microscopes revealed an overview of the meiotic pattern of the tide animals. The eggs have been fertilized early at germinal vesicle stage, followed by germinal vesicle break down (GVBD), but pre-mitotic aster like structure could not be resolved by the methods employed in this work. The meiotic features, such as rotation-shift movement of spindle fibers, behavior of spermatozoonmonaster in the egg cytoplasm and active spindle fiber of the 1st polar body, have been observed. The antitubulin-FITC fluorescence show the 2nd meiotic apparatus appeared firstly parallel to the tangential line of the oolemma, proceeding the meiosis, its bipolarity is rotated and shifted towards the oolemma. The polar bodysite of the oolemma was not amorphous, but active in a sense of anti-tubulin-FITC reactions during the extrusions of the polar bodies. The immunofluorescence reactions of the spermatozoon centriole appeared at a later stage of the 2nd meiosis. During the time periods, the fertilized spermatozoon resided in the egg cytoplasm. Activating the centrioles, spermatozoon approaches towards the chromosomal materials of the 2nd oocyte. This suggests that spermatozoon centrioles initiate and play a roll to fuse male and female pronuclei.

Characteristics of Fermentation and Aging by Different Adding of Brewing Water in Korean Traditional Cheongju (가수량을 달리한 전통 청주의 발효 및 숙성 특성 연구)

  • Moon, Jin-Seok;Kong, Tae-In;Cheong, Chul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.8
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    • pp.5468-5475
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    • 2015
  • This present work was aimed to analyse characteristics of fermentation and aging of Korean traditional cheongju prepared by adding of different brewing water. The three different mashes were used for fermentation and maturation. The cheongju(A) was prepared without adding of brewing water in two stage mashing. Cheongju(B) and cheongju(C) were made with adding of 1 liter and 2 liter brewing water in two stage mashing respectively whereas the cheongju(B) and cheongju(C) showed higher fermentation ability than that of cheongju(A) regarding to pH, ethanol, specific gravity and sugar concentration(brix). In terms of volatile compounds content after six months aging, cheongju(A and B) prepared by adding brewing water showed the higher content of ethyl acetate than that of cheong(C) and the concentrations were maintained during the aging period. In addition, the content of fusel oil(n-propanol, i-butanol, n-butanol, i-bmyl alcohol, n-bmyl alcohol)indicated similar pattern as ethyl acetate. The organic acid of cheongju B(4873.46 mg/l) and C(4963.12 mg/l) also indicated the higher content than that of cheongju A(4661.47 mg/l). In conclusion, cheongju B and C prepared by adding brewing water in two stage mashing showed better quality and taste than that of cheongju A.

A Study on the Publication and Composition of JujaDaejeon Anthologies in the Joseon dynasty (조선시대 『주자대전』 선집서의 간행과 구성에 관한 연구)

  • Choi, Kyunghun
    • Journal of the Korean Society for Library and Information Science
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    • v.54 no.2
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    • pp.435-455
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    • 2020
  • The purpose of this study is to examine the publication, composition, method of composition, and acceptance patterns of JujaDaejeon anthologies edited by Joseon scholars in the Joseon dynasty. When a large amount of JujaDaejeon was published in the 16th century, anthologies of JujajaDaejeon was compiled, published and learned as a way to understand it. A total of 13 kinds of JujajaDaejeon anthologies were published, including six kinds in the early Joseon period and seven kinds in the late Joseon period. And the composition of main anthologies showed a trend that was supplemented by Jeong Gyeong-se's Jumunjakhae from Lee Hwang's Jujaseojeolyo, and aggregated into Song Si-yeol's Jeoljaktongpyeon(boyu). JujaDaejeon consists of total 3,645 works except for poems. Among them, 1,734 works were selected by 13 anthologies. The theme of a work with a high cumulative number of selections is the virtue and attitude of the king, policy proposals, the appointment of talent, the duty of subjects, criteria for evaluating historical figures, opposition to harmony with Jin and territorial restoration, and academic discussions. This study is expected to be meaningful in the field of the research on the acceptance of the foreign books and acceptance of the Zhu Xi's works in the Joseon dynasty.

The Regional Characteristics of Overseas Koreans (해외 한인의 지역별 특성)

  • 정성호
    • Korea journal of population studies
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    • v.21 no.1
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    • pp.105-128
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    • 1998
  • There are about 5,300,000 overseas Koreans in the world. This is about 11.8 percent of the total population of the Korean peninsular. They reside in more than one hundred nations. This exodus occurred due to forced emigration, escape from oppressive regimes, and economic opportunity. Most of them are living in the four regions, that is, China, Japan, America, and Central Asia. The purpose of this paper is to examine the pattern of Korean migration to overseas and to compare the life style of overseas Koreans. The data are taken from a sample survey, which was conducted in China, Japan, America, and Central Asia. A total of 300 respondents were interviewed in each country. The result shows that there are some differences in the lives of overseas Koreans. For example, the Koreans in Central Asia may have suffered the greatest hardship, the similar case was found in the Koreans in China. By contrast, the issue of ethnic conflict becomes the most serious problem in the Koreans in Japan. This study also shows many aspects of common Korean heritage, that is, hard work, diligence, and high level of education. In addition, the study indicates that overseas Koreans are trying to retain Korean traditional values and relationships in their families.

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Design of Compound Knowledge Repository for Recommendation System (추천시스템을 위한 복합지식저장소 설계)

  • Han, Jung-Soo;Kim, Gui-Jung
    • Journal of Digital Convergence
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    • v.10 no.11
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    • pp.427-432
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    • 2012
  • The article herein suggested a compound repository and a descriptive method to develop a compound knowledge process. A data target saved in a compound knowledge repository suggested in this article includes all compound knowledge meta data and digital resources, which can be divided into the three following factors according to the purpose: user roles, functional elements, and service ranges. The three factors are basic components to describe abstract models of repository. In this article, meta data of compound knowledge are defined by being classified into the two factors. A component stands for the property about a main agent, activity unit or resource that use and create knowledge, and a context presents the context in which knowledge object are included. An agent of the compound knowledge process performs classification, registration, and pattern information management of composite knowledge, and serves as data flow and processing between compound knowledge repository and user. The agent of the compound knowledge process consists of the following functions: warning to inform data search and extraction, data collection and output for data exchange in an distributed environment, storage and registration for data, request and transmission to call for physical material wanted after search of meta data. In this article, the construction of a compound knowledge repository for recommendation system to be developed can serve a role to enhance learning productivity through real-time visualization of timely knowledge by presenting well-put various contents to users in the field of industry to occur work and learning at the same time.

Study of Wooden Chukmok and Chukdu Used for East Asian Mounting (동양 장황에 사용된 축목과 축두에 관한 연구)

  • Jang, Yeonhee
    • Conservation Science in Museum
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    • v.19
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    • pp.53-68
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    • 2018
  • Hanging scrolls and handscrolls are common mounting for East Asian painting and calligraphy in which wooden Chukmok with Chukdu of various materials are attached either at the top and bottom or at each side of a work. Hanging scroll paintings or calligraphy can be hung for appreciation and rolled up for preservation. The Chukmok and Chukdu of a hanging scroll were made from different materials and were known by distinct names in Korea, China, and Japan. In Korea, the wooden Chukmok were called sanghachukhoengmok(上下軸橫木), which means horizontal wooden bars for the top and bottom axes. The wooden Chukdu were called Chukdu(軸頭), meaning the head of an axis. These Chukmok and Chukdu were made of Korean red pine, nut pine, or shiny xylosma. In China, the rod was called zhougan(軸杆) and zhoutou(軸頭), and they were made of Japanese cedar, sappan wood, or red sandalwood. In Japan, the top rod was called hassou(八双; 八裝) and the bottom jikugi(軸木), and they were made of Japanese cedar, red sandalwood, or crystal. In Korean hanging scrolls, the cross section of a Chukdu is either flat or round, and it can be either patterned or patternless. The designs include concentric circles, two circles, and three circles. Among the portraits of meritorious subjects analyzed in this study, three examples feature concentric circles on Chukdu with a flat cross section, which coincides with most of the king's instructions housed at the Jangseogak Archives. This suggests that flat Chukdu with a concentric circle pattern were used for binding most of the paintings of meritorious subjects commissioned by the royal court.