• Journal of Preventive Medicine and Public Health
• /
• 제31권4호
• /
• pp.801-813
• /
• 1998

우리 나라의 주요사망원인에 해당하는 암질환을 대상으로 YLD를 측정하여 주요암질환간 질병부담의 우선 순위 측정하고 이의 활용범위를 알아보고자 수행한 본 연구에서 다음과 같은 결과를 얻었다. 우리 나라 남성의 암으로 인한 질병부담의 우선 순위 위암(4081.4년), 간암(3104.2년), 대장 및 직장암(3086.2년), 식도암(1511.9년), 폐암(1166.7년), 췌장암(1093.8년), 방광암(665.6년), 전립선암(421.7년), 백혈병(397.2년), 임파선암(259.7년)으로 계산되었다. 여성의 경우 암으로 인한 질병부담의 우선 순위 위암(2707.1년), 식도암(1536.7년), 간암(1468.5년), 자궁암(1311.8년), 난소암(974.3년), 췌장암(763.5년), 유방암(724.5년), 폐암(689.9년), 백혈병(351.3년), 임파선암(241.1년)로 계산되었다. 이러한 결과는 본 연구에 사용한 연구재료 및 연구 방법의 불완전성에도 불구하고 향후 보건의료정책의 우선순위결정, 즉 한정된 자원을 보다 더 효율적으로 활용하는데 보다 구체적인 정보를 계량적으로 제공해 줄 수 있다는 점에서 중요한 의의를 갖는다고 하겠다.

• 한국콘텐츠학회논문지
• /
• 제13권3호
• /
• pp.260-270
• /
• 2013

본 연구는 간호사의 노인의 성에 대한 지식, 태도, 교육 요구도를 파악하기 위한 서술적 조사연구이다. 연구 대상자는 전라북도의 I, K, J시의 종합병원 2곳과 노인 요양원(병원) 5곳에 근무하는 간호사 235명이었으며 자가보고 설문지를 이용하여 2012년 12월 1일부터 10일까지 자료 수집을 하였다. 자료 분석은 SPSS win 18.0프로그램을 이용하였다. 각 변수는 t-test, ANOVA, Pearson's correlation coefficients and DUNCAN을 사용하였다. 연구결과, 대상자의 성지식 평균점수는 $15.91{\pm}6.43$이고, 결혼(p=.024), 근무지(p<.001), 경력( p=.006), 성교육 필요여부(p<.001), 성교육 수용여부(p<.001) 등이 통계적으로 유의하였다. 성태도 평균점수는 $38.26{\pm}4.41$이고 근무지(p=.033), 노인 가족과 동거여부(p=.009), 성교육 필요여부(p<.001), 성교육 수용여부(p<.001)등이 통계적으로 유의하였다. 성교육 요구도의 평균점수는 $35.97{\pm}6.28$이며 연령(p=.023), 노인 가족과 동거여부(p=.014), 성교육 필요여부(p<.001), 성교육 수용여부(p<.001) 등이 통계적으로 유의하였다. 간호사의 노인의 성에 대한 성지식은 성태도(p<.001)와 성교육 요구도(p<.001))가 양의 상관관계로 나타났다. 이 연구 결과로 학부과정 및 간호사 대상으로 노인의 성에 관한 전반적인 교육의 필요성과 중요성을 알 수 있었으며, 이를 기초로 임상에서 노인들의 건강 사정 및 간호 중재 시 노인의 성에 대해 좀 더 적극적인 간호가 요구된다.

• 대한물리치료과학회지
• /
• 제6권1호
• /
• pp.897-903
• /
• 1999

Many out patients of the rehabilitation center complaint a pain caused by suffering of MPS, and it brings many different kind of social and ecinomical problems such as medical expenses and the reduction in work efficiency. Therefore, we conducted a research to present a fast and effective treatment to the MPS patients. this research was conducted from November, 1996 to January 1998 with eighteen outpatients who agreed to be the subjects to our reserach. We applied the electric acupuncture on 28 different trigger point on the patients with mostly muscular-skeletal pain and some tender and radiating pain. After the treatment, VRS, VAS, PRI were used to measure the degree of the pain on the patients third and seventh visits, and following results were found. 1. To apply EAP treatment, we acupunctured 6em-Iong needles on Tps region, then the electrodes of pulse generater pg-306 E.S.T were connected on the top of the needles. the electric acupuncture therapy was conducted for 20 minutes with the intensity of 4hz - 60hz(auto wave). The treated electric intensity was the level at which the patients did not feel discomfort. 2. Thirteen out of the 18 participated patients were in their 30s and 40s(72.2%), showing highest frequency. There were more female than male with the ratio of 1 to 1:2. 3. six out of the participated patients (33.3%) had the pain for less then a week, and the average duration of the pain of the participated patients wear 0.8 years. 4. The pain occured mostly in the upper trapezius by 6 part (21.4%), then in the gluteus medius region by 4 part (14.3%). Many of the patients with the pain in the upper back area accompanied varios kind of the referred pains such as radiculopathy, HIVD and Frozen shoulder. 5. MPS occured more frequently on the right side than left side then left side and it seemed to be due to the frequent use of the right hand. 6. There was almost no difference in the measurement of the intensity of the pain right before and after the EAP treatment. Howerver, there was significant decrease in the numerical values of the VAS, and a little bit of decrease in the numerical values of the PRI after the EAP treatment. 7. Based on the results of this present research, it can be concluded that EAP can be used for the treating the myofascial pain syndrome with promptness and safety in most cases.

• Environmental Analysis Health and Toxicology
• /
• 제21권2호
• /
• pp.103-113
• /
• 2006

This study examined effects of crude oil on the phase II drug-metabolizing enzymes UDP-glucuronosyl transferase (UDPGT) and glutathione S-transferase (GST) in mussel Mytilus edulis and rockfish Sebastes schlegeli, a representative bivalve and a culture fish, respectively. This work also intended indirectly to evaluate the post impact recovery from the massive oil tanker spillage accidents occurred during the summer of 1995 in the sea area off Yosu City, Chonnam. For these, enzyme activities of UDPGT and GST were examined in the fish and mussel following laboratory exposure to fresh crude oil, weathered oil, field-obtained oil residues, or in the field biota samples. Decreased GST activity was observed in rock fish following exposure to oil-soluble fraction (OSF) of fresh oil. A similar diminished GST activity was also observed after OSF of artificially weathered oil. OSF of field oil residues retrieved from the spillage area approximately 1 year later also exerted a slight inhibition of GST to rockfish. There was neither a change in UDPGT in rockfish, nor were there changes in mussel in both enzymes to any oil fractions. We could not observe any difference in the two enzymes either in rockfish or mussel sampled from the field during $1.5{\sim}2.0$ years post spillage, indicating that their enzyme systems might had been recovered by the sampling time. In conclusion, it seems that the inhibition of GST activity in rockfish is a biomarker response to crude oil exposure. The results, however, must be interpreted with care, as the inhibition nay reflect various factors such as oil concentration, duration and water temperature.

• 한국임상수의학회지
• /
• 제28권1호
• /
• pp.52-56
• /
• 2011

Acute renal injury induced by ischemia is a major cause of high morbidity and mortality in hospitalized patients and a common complication in hospitalized patients. Thus, the work with acute renal failure and renal ischemia has been studied for many years. Although serum creatinine concentration that is widely used as an index of renal function performs fairly well for estimating kidney function in patients with stable chronic kidney disease, it performs poorly in the setting of acute disease. Thus, an ideal biomarker for acute kidney injury would help clinicians and scientists diagnose the most common form of acute kidney injury in hospitalized patients, acute tubular necrosis, early and accurately, and may aid to risk-stratify patients with acute kidney injury by predicting the need for renal replacement therapy, the duration of acute kidney injury, the length of stay and mortality. In this study, renal ischemia and reperfusion were performed by clapming and un-clamping right renal artery in miniature pigs. Plasma blood urea nitrogen (BUN) and creatinine were examined at pre- clamping, after-clamping at 0, 1 and 3 hours. And we searched initial indicators in these samples. Also, renal tissue was collected and searched the initial indicator by PCR and western blotting. As a result, hypoxia inducible factor $1{\alpha}$ ($HIF1{\alpha}$), nuclear factor kappa-B ($NF{\kappa}B$), $I{\kappa}B$, erythropoietin (EPO), erythropoietin receptor (EPOR), angiopoietin-1 and vascular endothelial growth factor (VEGF) were showed significant changes among the renal protein. $HIF1{\alpha}$, EPO, and EPOR were showed significant changes among the renal gene. Thus, these markers will be used as initial diagnosis of acute renal failure.

• 한국건설관리학회논문집
• /
• 제16권5호
• /
• pp.54-64
• /
• 2015

모듈러 건축공법은 공장 생산, 운송, 현장설치 프로세스를 통해 기존 현장중심 건축공법에 비해 품질향상 및 공기단축이 가능한 특징을 가지고 있다. 특히 모듈러 유닛의 제작과 시공이 분리되어 수행되기 때문에 다수의 프로젝트가 동시에 수행될 경우 각 프로젝트에 따라 생산해야하는 모듈의 크기, 수량, 납기일, 생산 유형 및 과정을 고려하는 SCM(Supply Chain Management) 관점의 공장 생산 공정 계획 수립이 필요하다. 그러나 현재 모듈러 유닛 공장 생산 계획은 개별 프로젝트 중심으로 수립되고 있어 다중 모듈러 건축 프로젝트 수행 시 모듈러 유닛 제작공장의 한정된 자원과 설치 현장별 프로젝트 요구조건들을 동시에 고려한 공장 생산계획을 도출하는데 한계가 있다. 따라서 본 연구에서는 다양한 변수 간 상호 연계성 및 제약조건으로 공정 계획 최적화 결과 도출이 가능한 유전자 알고리즘 방법을 통해 모듈러 유닛 제작공장의 한정된 자원과 설치 현장별 요구사항이 반영된 모듈러 유닛 공장 생산 공정계획 최적화 수립 모델을 제시하며 이를 사례분석을 통해 검증하였다. 연구 결과, 기존 다중프로젝트의 공장생산계획에 비해 평균 7.9%의 현장설치 공기단축 및 43%의 최대 야적장 이용률 감소가 가능하였다. 향후 본 연구 내용을 바탕으로 제약 조건 범위 확장 및 생산성 데이터 추가가 될 경우 다중 모듈러 건축 프로젝트의 모듈러 유닛 공장 생산 계획 수립과 현장시공프로세스 구축을 동시에 지원할 수 있는 기초 자료로 활용될 수 있다.

• Child Health Nursing Research
• /
• 제6권2호
• /
• pp.199-211
• /
• 2000

Today, more chronically ill and handicapped children are being cared for at home by a family member caregiver. The task of caring for a family member may feel burden that the caregiver has less time and money and more work. Family functioning and their burden have influence on coping and adaptation of families with chronically-ill children. This study attempted to identify the levels of burden and family functioning in families of children with cerebral palsy and to examine their relationships. The instruments were burden scale developed by Suh and Oh(1993), and a modified Feetham Family Functioning Survey based on Roberts and Feetham.(1982). The subjects were 98 parents of children, under 15 years, who have cerebral palsy and being treated and living in Pusan. Data were collected through a self-administered question- aire from April 26 to May 29. The collected data were tested using frequencies, percentiles, means, t-test, ANOVA, and Pearson correlation coefficient with SPSSWIN program. The results of this study were as follows ; 1. The mean rating scores of burden and family functioning were 2.79±.51 and 4.12±.69, respectively. 2. The relationships between general character- istics and burden were statistically significant difference : degree of children's handicap(F=6.333, P<.01). The relationships between general characteristics and family functioning were statistically significant differences : familial relation with the children(F=3.628, P<.05), caregiver's health status(F=4.359, P<.05), age of children (F=4.185, P<.05), and duration of treatment (F=6.802, P<.01). 3. In families of children with cerebral palsy, there was significantly negative correlation between the burden of parents and the performance of family functioning(r=-.230, P<.05). There were significantly negative correlations between the burden of parents and the satisfaction of family functioning (r=-.211, P<.05), and between the perceived importance and the satisfaction of family functioning(r=-.481, P<.01); however, there was a positive correlation between the performance and the perceived importance of family functioning(r=.425, P<.01). In conclusion, this study suggests that families of children with cerebral palsy need family-focused nursing interventions as supportive care for relieving their burden and for improving family functioning.

• 한국사회복지학
• /
• 제54권
• /
• pp.221-243
• /
• 2003

활동이론은 노년기 역할상실 혹은 감소에 따른 대체적 역할로서 새로운 사회활동에 참여하게 되어 노년기의 생활만족감을 증진시킬 수 있다는 이론이다. 본 연구는 이와 같은 활동이론을 기초로 노인의 자원봉사활동이 노년기 역할감소에 따른 대체적 역할로서 노인의 생활만족감에 영양을 미치는지를 분석하고자 했다. 연구대상은 서울시내 23개 자원봉사센터를 통해 활동하고 있는 55세 이상 노인자원봉사자 192명이다. 활동이론은 직업유무, 가구형태, 봉사활동 성취내용으로 조작좌하였으며, 분석결과, 직업유무는 활동빈도와 활동시간에, 봉사활동 성취내용 중 사회적 성취는 지속기간에만 영향을 미쳤으며, 가구형태는 어떠한 영향도 미치지 못했다. 또한 지속기간이나 활동빈도, 활동시간 등 자원봉사에 대한 헌신은 노인의 생활만족도에 어떠한 영향도 미치지 못했다. 오히려 노인의 자원봉사활동 참여는 활동이론 변수 이외에 봉사활동에 대한 보상, 건강상태, 교육수준, 성별에 의해 설명될 수 있었으며, 노인자원봉사자의 생활만족도에는 동거가족형태나 경제수준이 중요한 영향을 미치고 있었다. 이와 같은 분석결과는 활동이론만으로 우리나라 노인의 자원봉사활동을 전적으로 설명할 수 없음을 의미한다. 또한 노인들에게 있어 자원봉사활동은 시간의 투입보다는 봉사활동을 통한 성취감과 이들 활동에 대한 지지 혹은 관심 등의 질적인 측면이 더 중요할 수 있음을 시사한다고 하겠다. 본 연구는 우리나라 노인 자원봉사 분야에 있어 활동이론을 기초로 한 최초의 실증연구라는 점에서 중요한 의의를 갖고 있다고 할 수 있다.

• Molecular & Cellular Toxicology
• /
• 제2권2호
• /
• pp.134-140
• /
• 2006

Because shipyard workers are involved with various manufacturing process in shipyard industry, and they are exposed to many kinds of hazardous materials. Especially, painting workers were exposed polycyclic aromatic hydrocarbons (PAH). This study was conducted to assess the exposure status of PAH based on job-exposure matrix. We investigated the effect of genetic polymorphism of xenobiotic metabolism enzymes involved in PAH metabolism on levels of urinary metabolite. A total of 93 shipbuilding workers were recruited in this study. Questionnaire variables were age, sex, use of personal protective equipment, smoking, drinking, and work duration. The urinary metabolite was collected in the afternoon and corrected by urinary creatinine concentration. The genotypes of CYP1A1, CYP2E1, GSTM1, GSTT1 and UGT1A6 were investigated by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods with DNA extracted from venous blood. Urinary 1-OHP levels were significantly higher in direct exposured group (spray and touch-up) than indirect exposed group. Urinary 1-OHP, concentration of the high exposure with wild type of UGT1A6 was significantlyhigher than that of the high exposure with other UGT1A6 genotype. In multiple regression analysis of urinary 1-OHP, the regression coefficient of job grade was statistically significant (p<0.05) and UGT1A6 was not significant but a trend (p<0.1). The grade of exposure affected urinary PAH concentration was statistically significant. But genetic polymorphism of xenobiotics metabolism enzymes was not statistically significant. Further investigation of genetic polymorphism with large sample size is needed.

• Journal of Preventive Medicine and Public Health
• /
• 제38권2호
• /
• pp.208-214
• /
• 2005

Objectives: This study was performed to examine the factors affecting re-smoking in male workers. Methods: A self-administrated questionnaire survey was conducted during April 2003 to examine the smoking state of 1,154 employees of a company that launched a smoking cessation campaign in1998. Five hundred and eighty seven persons, who had stopped smoking for at least one week, were selected as the final study subjects. This study collected data on smoking cessation success or failure for 6 months, and looked at the factors having an effect on re-smoking within this period. This study employed the Health Belief Model as its theoretical basis. Results: The re-smoking rate of the 587 study subjects who had stopped smoking for at least one week was 44.8% within the 6 month period. In a simple analysis, the re-smoking rates were higher in workers with a low age, on day and night shifts, blue collar, of a low rank, where this was their second attempt at smoking cessation and for those with a shorter job duration (p<0.05). Of the cues to action variables in the Heath Belief Model, re-smoking was significantly related with the perceived susceptibility factor, economic advantages of smoking cessation among the perceived benefits factor, the degree of cessation trial's barrier of the perceived barriers factor, smoking symptom experience, recognition of the degree of harmfulness of environmental tobacco smoke and the existence of chronic disease due to smoking (p<0.05). In the multiple logistic regression analysis for re-smoking, the significant variables were age, perceived susceptibility for disease, economic advantages due to smoking cessation, the perceived barrier for smoking cessation, recognition on the degree of harmfulness of environmental tobacco smoke, the existence of chronic disease due to smoking and the number of attempts at smoking cessation (p<0.05). Conclusion: From the result of this study, for an effective smoking ban policy within the work place, health education that improves the knowledge of the adverse health effects of smoking and the harmfulness of environmental tobacco smoke will be required, as well as counter plans to reduce the barriers for smoking cessation.