• 제목/요약/키워드: Won Ya

검색결과 76건 처리시간 0.03초

4종 창포류의 성분 패턴 및 항산화 효능 비교 (Comparative Study of Changpo(Ch$\={a}$ngp$\'{u}$) species on Antioxidant Activity and HPLC Pattern Analysis)

  • 최고야;고병섭;이미영;채성욱;김영화;육진아;백지성;이혜원
    • 대한본초학회지
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    • 제26권1호
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    • pp.13-19
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    • 2011
  • Objective : This study was to compare antioxidant activity and HPLC pattern analysis from 4 species of changpo(ch$\={a}$ngp$\'{u}$). Methods : To compare the antioxidant activity and HPLC pattern analysis from the 4 species of changpo, we performed the in vitro anti-oxidative activity assays and HPLC analysis from 70% ethanol extracts of Acorus gramineus Sol. (=AG), A. tatarinowii Schott (=AT), A. calamus L. (=AC) and Anemone altaica Fisch. ex C.A.Mey (=AA) taken in the herbal medicine market of Korea. Results : AG has the most effective anti-oxidative activity among 4 species of changpo. As the HPLC pattern analysis, AT was detected the unknown peak at retention time 14.9 min whereas AG was not showed any peak at the same retention time. These results suggest that AG could be used rather than AT when it need to be prescribed as anti-oxidative medicine. Conclusions : This result can be used as the basic data contributing to the stability of AG according to an appropriate clinical application.

Ishige okamurae reduces blood glucose levels in high-fat diet mice and improves glucose metabolism in the skeletal muscle and pancreas

  • Yang, Hye-Won;Son, Myeongjoo;Choi, Junwon;Oh, Seyeon;Jeon, You-Jin;Byun, Kyunghee;Ryu, Bo Mi
    • Fisheries and Aquatic Sciences
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    • 제23권9호
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    • pp.24.1-24.9
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    • 2020
  • Brown alga (Ishige okamurae; IO) dietary supplements have been reported to possess anti-diabetic properties. However, the effects of IO supplements have not been evaluated on glucose metabolism in the pancreas and skeletal muscle. C57BL/6 N male mice (age, 7 weeks) were arranged in five groups: a chow diet with 0.9% saline (NFD/saline group), high-fat diet (HFD) with 0.9% saline (HFD/saline group). high-fat diet with 25 mg/kg IO extract (HFD/25/IOE). high-fat diet with 50 mg/kg IO extract (HFD/50/IOE), and high-fat diet with 75 mg/kg IO extract (HFD/75/IOE). After 4 weeks, the plasma, pancreas, and skeletal muscle samples were collected for biochemical analyses. IOE significantly ameliorated glucose tolerance impairment and fasting and 2 h blood glucose level in HFD mice. IOE also stimulated the protein expressions of the glucose transporters (GLUTs) including GLUT2 and GLUT4 and those of their related transcription factors in the pancreases and skeletal muscles of HFD mice, enhanced glucose metabolism, and regulated blood glucose level. Our results suggest Ishige okamurae extract may reduce blood glucose levels by improving glucose metabolism in the pancreas and skeletal muscle in HFD-induced diabetes.

꿀풀과 6개종의 Chloroplast 부위 유전자를 이용한 익모초(益母草) 감별 PCR 분석 (PCR Analysis for the Discrimination of Leonuri Herba Medicine on the Basis of Chloroplast DNA Sequence Comparison in Six Lamiaceae Species)

  • 이재웅;김영화;최고야;고병섭;김영선;채성욱;이혜원;오승은;박상언;이미영
    • 대한본초학회지
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    • 제26권3호
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    • pp.15-21
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    • 2011
  • Objectives : The application of polymerase chain reaction (PCR) for the discrimination of the herbal medicine Leonuri Herba (Leonurus japonicus) was evaluated by the comparison of the DNA sequence with Lamiaceae herbal medicine. Method : Genetic analysis showed that phylogenetic tree and comparing sequences through the DNA analysis of rbcL (ribulose-1, 5-bisphosphatecarboxylase) region and trnL-F (tRNA-Leu, trnL-trnF intergeni cspacer, and tRNA-Phe) region of chloroplast DNA from six Lamiaceae sold in market. And we developed IMCF and IMCR primers in order to distinction Leonuri Herba in six Lamiaceae using rbcL and trnL-F sequences. Results : Genetic analysis showed that six Lamiaceae showed individual group on phylogenetic tree. PCR amplification product of Leonuri Herba and another five Lamiaceae were developed for amplification of a 281 bp sequence and the specific PCR amplification of a 460 bp sequence that was exclusive to Leonuri Herba was designed using IMCF and IMCR primers. Conclusion : PCR analysis based on the chloroplast DNA sequences allows the discrimination of Leonuri Herba-based medicine.

한국 성인 비만여성의 체지방 분포와 월경 장애의 상관성 분석 (Relationship between body fat distribution and menstrual disorder in Obese Pre-menopausal Korean Women)

  • 최가야;송미연;신현대;정원석
    • 한방비만학회지
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    • 제4권1호
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    • pp.23-31
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    • 2004
  • Background: Obesity is associated with menstrual disorder. Especially, upper-body obesity affects on female reproductive function. Objectives: The goals were to investigate relation between fat distribution and menstrual disorder in obese pre-menopausal Korean females. The hypothesis were tested that there is a relation between upper body obesity and menstrual disorder. Design: A cross-sectional evaluation of 66 Females (baseline age $32.15{\pm}7,32)$ with body mass index $31.22{\pm}4.05\;kg/m^2$. Body composition was measured using bioimpedence analysis (BIA) and anthropometry was done by same observer. VAS and Multidimensional verval rating scale(MVRS) were checked for menstrual pain. Dual-Energy X-ray Absorptiometry (DXA) was measured for evaluating body fat distribution. Menstrual disorder and body fat distribution were compared using statistical methods. Results: TLFR and WH ratio was higher in menstrual cyclic disorder group than controls. There was negative relationship between VAS and TLFR. Conclusions: The data shows that disorder of menstrual cycle was associated with upper body obesity. WH ratio could be one of the factor of menstrual disorder. VAS was correlated with lower body obesity. Further studies for role of upper body fat distribution on female reproductive function and relationship between menstrual pain and fat distribution thought to be needed.

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SWMM 모형을 활용한 평야부 관개효율 및 용수공급 취약성 평가 (Assessment of Irrigation Efficiency and Water Supply Vulnerability Using SWMM)

  • 신지현;남원호;방나경;김한중;안현욱;이광야
    • 한국농공학회논문집
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    • 제62권6호
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    • pp.73-83
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    • 2020
  • Agricultural drought is a natural phenomenon that is difficult to observe and quantitatively express, and agricultural water use is high and usage patterns are diverse, so even if there is a lack of rainfall. The frequency and severity of agricultural drought are increased during the irrigation period where the demand for agricultural water is generated, and reasonable and efficient management of agricultural water for stable water supply is required. As one method to solve the water shortage of agricultural water in an unstructured method, it is necessary to analyze the appropriate supply amount and supply method through simulation from the intake works to the canals organization and paddy field. In this study, irrigation efficiency was analyzed for irrigation systems from April to September over the past three years from the Musu Reservoir located in Jincheon-gun, Chungcheongbuk-do and Pungjeon Reservoir located in Seosan-si, Chungcheongnam-do. SWMM (Storm Water Management Model) was used to collect agricultural water, and irrigation efficiency analysis was conducted using adequacy indicators, and water supply vulnerability. The results of the agricultural water distribution simulation, irrigation efficiency and water supply vulnerability assessment are thought to help the overall understanding of the agricultural water supply and the efficient water management through preliminary analysis of the methods of agricultural water supply in case of drought events.

Evaluation of Bilayer Polycaprolactone Scaffold for Osteochondral Regeneration in Rabbits

  • Park, Min-hyeok;Hwang, Ya-won;Jeong, Do-Sun;Kim, Gon-hyung
    • 한국임상수의학회지
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    • 제33권6호
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    • pp.332-339
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    • 2016
  • Polycaprolactone (PCL) scaffold have been developed as an alternative to natural donor tissue to repair a large osteochondral defect. The objective of this study is to evaluate efficacy and biocompatibility of bilayer PCL scaffold implanted for osteochondral repair in rabbit. Twenty-two male New Zealand White rabbits were used in this animal experiment. Rabbits were divided into three groups. Experimental surgery was carried out under general anesthesia. Osteochondral defects (5 mm diameter and 5 mm deep) were made in the center of the patellar groove using a 5 mm diameter biopsy punch. In group I (3D plotting) and group II (salt-leaching), the scaffold was implanted using the press-fitted technique into the defect. In control group, after osteochondral defect was created, the defect was left without implant. After four and eight weeks, rabbits were sacrificed and the defects were evaluated by macro -and microscopical methods. There were not found animal death and severe inflammatory evidence during the experimental periods. There were no significant differences between the experimental groups in gross evaluation. However the group I scored significantly higher than group II at 8 weeks in histological evaluation (P < 0.05). The 3-D plotting PCL scaffold was more suitable method for reconstruction of osteochondral defect than a salt-leaching PCL scaffold.

농민 물절약 교육 실시 (Farmer's Education for Water Conservation)

  • 이슬기;최경숙;도종원;이광야
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2018년도 학술발표회
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    • pp.484-484
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    • 2018
  • 본 연구에서는 농림축산식품부 "농업 농촌부문 가뭄대응 종합대책(2015)"의 일환으로 가뭄에 의한 농촌지역 물부족 문제를 극복하기 위한 농민 물절약 교육을 실시하였다. 물절약 교육을 통해 가뭄상황에 적응할 수 있도록 하기 위해 물절약 교육 시범대상지역은 농민농업가뭄지도 및 재해연보 등의 자료를 활용하여 가뭄 취약지역을 8개도별로 한국농어촌공사 관할지구로 선별하여 선정하였다. 최종적으로 농민 물절약 시범교육이 실시된 지역은 경기 평택 석정지구, 강원 철원 토교지구, 충북 음성 용계지구, 충남 서산 신창지구, 경북 문경 경천지구, 경남 거창 가북지구, 전북 고창 신림지구, 전남 영암 월악지구가 선정되었다. 시범교육실시 앞서 대상지구의 용 배수로 현황, 수로노후화, 농민 물이용 실태 등 물손실 요인을 파악하였다. 시범교육은 기존과는 차별된 체험식 비주얼 물절약 교육이 실시되었으며, 시범대상지구별로 3단계 교육이 실시되었다. 1단계 교육은 이해단계로 플래쉬 동영상과 물이용 모의를 체험하게 하여 물 손실 원인 및 물 절약 방안을 모색하도록 하였다. 2단계 교육은 적용단계로서 물절약 시뮬레이터를 이용하여 평상시 농민의 물이용 관행에 따른 물손실 야기에 대한 이해와 가뭄시나리오에 따른 물 공급량 감소 시 농민 피해 및 가뭄극복을 위한 효율적인 물이용에 대한 효과를 이해시키고자 하였다. 또한 이를 통해 농민이 스스로 물절약을 위한 행동강령을 도출하도록 하였다. 마지막 3단계는 실천단계로 실제 현장여건에서의 물절약 실천을 도모하기 위해서, 현장에서의 물손실 상황 파악 및 현장여건에 맞는 물절약 실천방안을 도출하도록 하였다. 교육을 통해 농민의 물절약 필요성에 대한 공감대를 형성하고, 물절약을 스스로 실천할 수 있도록 유도 하고자 하였다. 물절약 교육의 효과를 파악하기 위해서 설문조사를 실시하였으며, 그 결과 농민들은 물절약의 필요성을 매우 높게 공감하며, 필지단위 물손실을 감소시키는 물꼬관리의 중요성을 인정하고, 농민 수로관리 참여에 대한 인식을 높이는 계기가 되었다.

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필지단위 관개용수 공급에 따른 농업가뭄진단 평가 (Agricultural Drought Assessment and Diagnosis Based on Spatiotemporal Water Supply in Irrigated Area)

  • 신지현;남원호;김하영;문영식;방나경;이정철;이광야
    • 한국농공학회논문집
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    • 제63권4호
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    • pp.1-12
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    • 2021
  • Agricultural drought is a natural phenomenon that is not easy to observe and predict and is difficult to quantify. In South Korea, the amount of agricultural water used is large and the types of use are varied, so even if an agricultural drought occurs due to insufficient precipitation, the drought actually felt in the irrigated area is it can be temporally and spatially different. In order to interpret the general drought in the past, drought disasters were evaluated using single indicators such as drought damage area, precipitation shortage status, and drought index, and a comprehensive drought management system is needed through drought diagnosis survey. Therefore, we intend to conduct research on agricultural drought assessment and diagnosis using re-evaluation of agricultural facilities and irrigation water supply network due to changes in various conditions such as climate change, irrigation canal network, and evaluation of water supply capacity of agricultural facilities. In this study, agricultural drought diagnosis was conducted on two agricultural reservoirs located in Sangju, Gyeongsangbuk-do, with structural or non-structural evaluations to increase spatiotemporal water supply and efficiency in terms of water shortages. The results of the agricultural drought diagnosis evaluation can be used to identify irrigated areas and canal network vulnerable to drought and to prioritize drought response.

계층화분석 및 엔트로피 가중치 산정 방법에 따른 농업가뭄재해 취약성 평가 (Evaluation of Agricultural Drought Disaster Vulnerability Using Analytic Hierarchy Process (AHP) and Entropy Weighting Method)

  • 문영식;남원호;양미혜;신지현;전민기;김태곤;이승용;이광야
    • 한국농공학회논문집
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    • 제63권3호
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    • pp.13-26
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    • 2021
  • Recent drought events in the South Korea and the magnitude of drought losses indicate the continuing vulnerability of the agricultural drought. Various studies have been performed on drought hazard assessment at the regional scales, but until recently, drought management has been response oriented with little attention to mitigation and preparedness. A vulnerability assessment is introduced in order to preemptively respond to agricultural drought and to predict the occurrence of drought. This paper presents a method for spatial, Geographic Information Systems-based assessment of agricultural drought vulnerability in South Korea. It was hypothesized that the key 14 items that define agricultural drought vulnerability were meteorological, agricultural reservoir, social, and adaptability factors. Also, this study is to analyze agricultural drought vulnerability by comparing vulnerability assessment according to weighting method. The weight of the evaluation elements is expressed through the Analytic Hierarchy Process (AHP), which includes subjective elements such as surveys, and the Entropy method using attribute information of the evaluation items. The agricultural drought vulnerability map was created through development of a numerical weighting scheme to evaluate the drought potential of the classes within each factor. This vulnerability assessment is calculated the vulnerability index based on the weight, and analyze the vulnerable map from 2015 to 2019. The identification of agricultural drought vulnerability is an essential step in addressing the issue of drought vulnerability in the South Korea and can lead to mitigation-oriented drought management and supports government policymaking.

EPA-SWMM 모델을 활용한 관개회귀수량 추정 (Estimation of irrigation return flow in agricultural reservoirs using EPA-SWMM)

  • 신지현;남원호;윤동현;정인균;이광야
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2023년도 학술발표회
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    • pp.50-50
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    • 2023
  • 농업용수는 우리나라 수자원 사용량 중 약 61%를 차지하고 있으며, 효율적인 수자원 관리를 위한 핵심적인 관리목표 중 하나이다. 논으로 공급되는 관개용수는 필지에서의 증발산량 및 침투량과 용배수로를 통한 자연적 및 인위적인 배수량으로 소비된다. 관개회귀수량 (irrigation return flow)은 관개를 통해 농경지에 공급된 수량 중 증발산에 의해 소비되지 않고 침투 또는 배수 등을 통해 하천으로 회귀되는 수량이다. 관개회귀수량 및 회귀율은 농업용수 물순환 관리에 중요한 역할을 하며, 관개용수 사용량 결정, 합리적인 용수의 공급과 수요 관리계획 및 수질 관리계획 등에 중요한 요소로 작용한다. 하지만, 기상, 작물, 토양 등의 물리적 요소와 농업용수 공급량, 물꼬 조절, 담수심 관리 방식 등 인위적 요소의 영향을 동시에 받기 때문에 그 기작이 복잡한 특징을 갖는다. 따라서, 합리적인 수자원 개발 계획 및 관리를 위해 정확한 관개회귀수량 추정 연구가 필수적이다. 본 연구에서는 전국 4대강 (한강, 금강, 낙동강, 영산강·섬진강) 권역 중심의 9개 대상지구를 선정하였으며, EPA-SWMM (Environmental Protection Agency-Storm Water Management Model) 모델 기반 수로 네트워크 모의를 활용한 수원공 단위 관개회귀수량을 산정하고자 한다. EPA-SWMM 모의 시 공급량은 농업기반시설관리시스템 (Rural Infrastructure Management System, RIMS) 저수율 자료와 수원공 단위용수량을 활용하였으며, 모의결과 시점부 공급량 및 배수량과 강수량, 증발산량 및 침투량을 활용하여 신속회귀수량과 지연회귀수량을 추정하였다. 본 연구 결과는 최적 농업용수 공급방안에 대한 기초자료 구축에 활용 가능할 것으로 사료된다.

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