• Title/Summary/Keyword: William J

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Agouti Gene의 Human Homologue의 Molecular Structure와 Chromosomal Mapping

  • Heajoon Y. Kwon;Scott J. Bultman;Christiane Loffler;Chen, Wen-Ji;Paul J. Furdon;John G. Powell;Usala, Anton-Lewis;William Wilkison;Ingo Hansman
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.11a
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    • pp.55-64
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    • 1996
  • mouse chromesome2에 있는 agouti locus는 정상적으로는 털색깔을 조절하는 gene이다. mouse agouti gene은 최근에 cloning 되었고 131 amino acid peptide와 consensus signal peptide를 encode한다고 보고되었다. 이 논문에서 interspecies-DNA hybridization approach를 이용하여 mouse agouti gene의 human homologue를 cloning 하였다. Sequence analysis 결과, 이는 mouse gene에 85% 유사하였고 consensus signal peptide sequence 를 포함하는 132 amino acid를 coding하였다. somatic-cell hybrid mapping pannel과 Fluorescence-in-situ hybridization에 의한 chromosomal mapping을 한 결과, agouti gene은 MODY (maturity onset diabetes of the young), myeloid leukemia locus 등이 위치한 human chromosome 20q 11.2에 mapping 되었다. 성인 tissue로부터 추출한 RNA를 이용한 발현연구에 의하면 human agouti gene은 adipose tissue와 teatis에 발현되었다.

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Channel Gap Measurements of Irradiated Plate Fuel and Comparison with Post-Irradiation Plate Thickness

  • James A. Smith;Casey J. Jesse;William A. Hanson;Clark L. Scott;David L. Cottle
    • Nuclear Engineering and Technology
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    • v.55 no.6
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    • pp.2195-2205
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    • 2023
  • One of the salient nuclear fuel performance parameters for new fuel types under development is changes in fuel thickness. To test the new commercially fabricated U-10Mo monolithic plate-type fuel, an irradiation experiment was designed that consisted of multiple mini-plate capsules distributed within the Advanced Test Reactor (ATR) core, the mini-plate 1 (MP-1) experiment. Each capsule contains eight mini-plates that were either fueled or "dummy" plates. Fuel thickness changes within a fuel assembly can be characterized by measuring the gaps between the plates ultrasonically. The channel gap probe (CGP) system is designed to measure the gaps between the plates and will provide information that supports qualification of U-10Mo monolithic fuel. This study will discuss the design and the results from the use of a custom-designed CGP system for characterizing the gaps between mini-plates within the MP-1 capsules. To ensure accurate and repeatable data, acceptance and calibration procedures have been developed. Unfortunately, there is no "gold" standard measurement to compare to CGP measurements. An effort was made to use plate thickness obtained from post-irradiation measurements to derive channel gap estimates for comparison with the CGP characterization.

Expanding the Limits of Membrane-Based Gas Separation Materials

  • Koros, William J.
    • Proceedings of the Membrane Society of Korea Conference
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    • 1995.09a
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    • pp.21-22
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    • 1995
  • Gas separation science and technology is among the most rapidly growing areas involving membrane-based processes. Nitrogen enrichment of air, hydrogen recovery from a broad array of stream types, and removal of acid gases from natural gases are typical of the applications in this field. Great progress has been made in the discovery of guidelines optimization of polymer structures with simultaneously high permeabilities and selectivities for these important gas pairs. The development of thin-skinned asymmetric hollow fibers have also provided structures with extremely high permeation fluxes. Especially in the case of O$_{2}$/N$_{2}$ separations, the rate of improvements in new polymeric materials for gas separations appears to be slowing to a halt. Evidence will be presented, however, that the practical tradeoff between membrane permeability and selectivity has not been reached.

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The Role of Parent-Child Relationships in Developing Self-Authorship Among Korean College Females

  • Lee, So-Young;Meszaros, Peggy S.;Creamer, Elizabeth G.;Laughlin, Anne;Burger, Carol J.
    • International Journal of Human Ecology
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    • v.7 no.1
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    • pp.111-119
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    • 2006
  • The purpose of our study is to explore dynamic mechanisms within families and self-authored decisions among Korean female college students. In particular, we investigated how parent-child interactions influence the development of self-authorship and self-authored decisions within Korean culture through interviews with 14 female college students. Results showed unique cultural influences on how female college students interacted with parents and interpreted and reflected parents' opinions in their self-authored decisions. These results suggest further research on gender differences and complex family influences on self-authored decisions within cultural contexts.

Young Stellar Objects and Dense Clouds in the W51 Region

  • Kang, Mi-Ju;Bieging, John H.;Kulesa, Craig A.;Lee, Yong-Ung;Choi, Min-Ho;Peters, William L.
    • The Bulletin of The Korean Astronomical Society
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    • v.35 no.2
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    • pp.72.1-72.1
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    • 2010
  • We present infrared and millimeter observations of the active star-forming complex W51. A $1.25\;deg\times1.00\;deg$ region that includes the W51 complex was covered in the J = 2 - 1 transition of the $^{12}CO$ and $^{13}CO$ molecules with the University of Arizona Heinrich Hertz Submillimeter Telescope. We use a statistical equilibrium code to estimate physical properties of the molecular gas. Using Spitzer data we identify young stellar objects (YSOs) and fit model spectral energy distributions to these sources and constrain their physical properties. We compare the molecular cloud morphology with the distribution of infrared and radio continuum sources and find associations between molecular clouds and YSOs. We estimate that about 1% of the cloud mass is currently in YSOs.

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A Comparative Study to Evaluate a Simple Method for the Management of Postoperative Bleeding Following Palatoplasty

  • Rossell-Perry, Percy;Schneider, William J.;Gavino-Gutierrez, Arquimedes M.
    • Archives of Plastic Surgery
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    • v.40 no.3
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    • pp.263-266
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    • 2013
  • Bleeding, is one of the most common postoperative complications after palatoplasty in patients with cleft palate. The purpose of this article is to present our experience using a Foley catheter balloon for perioperative palatoplasty bleeding management. A retrospective data analysis was performed for all cases of palatoplasty performed by the author from 1999 to 2012 that experienced postoperative hemorrhage. These patients were managed by utilizing posterior nasal compression with a Foley catheter balloon for the period 2006 to 2012. We have compared two methods (we use before 2006 the reoperative method) with regards to the later development of palatal fistulae and cases with reoperative hemostasis. The study found no statistically significant differences between the conventional and proposed method in relation to the development of palatal fistulae (P=0.7). These findings suggest that nasal packing using a Foley balloon is a safe and effective method for postoperative bleeding control after palatoplasty in patients with cleft palate.

A Structural Engineer's Approach to Differential Vertical Shortening in Tall Buildings

  • Matar, Sami S.;Faschan, William J.
    • International Journal of High-Rise Buildings
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    • v.6 no.1
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    • pp.73-82
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    • 2017
  • Vertical shortening in tall buildings would be of little concern if all vertical elements shortened evenly. However, vertical elements such as walls and columns may shorten different amounts due to different service axial stress levels. With height, the differential shortening may become significant and impact the strength design and serviceability of the building. Sometimes column transfers or other vertical structural irregularities may cause differential shortening. If differential shortening is not addressed properly, it can impact the serviceability of the building. This paper takes the perspective of a structural engineer in planning the design, predicting the shortening and its effects, and communicating the information to the contractor.

Securing RTP Packets Using Per-Packet Key Exchange for Real-Time Multimedia

  • Jung, Younchan;Festijo, Enrique;Atwood, J. William
    • ETRI Journal
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    • v.35 no.4
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    • pp.726-729
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    • 2013
  • For secure multimedia communications, existing encryption techniques use an online session key for the key exchange, for which key size is limited to less than 10 digits to accommodate the latency condition caused by user devices only being able to handle low computational loads. This condition results in poor security of recorded encrypted data. In this letter, we propose a packet key scheme that encrypts real-time packets using a different key per packet for multimedia applications. Therefore, a key of a relatively small size can provide after-transmission confidentiality to data of a real-time session.

Corrosion Protection of Automotive Steels by Novel Water-borne Primer Systems

  • Ooij, William J. van;Puomi, Paula
    • Corrosion Science and Technology
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    • v.6 no.5
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    • pp.239-244
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    • 2007
  • Corrosion protection of automotive steels has traditionally been assured by using a zinc phosphate metal pretreatment followed by the deposition of a cathodic electrocoat system. This system has been developed and optimized over the years into a highly robust and dependable system with a high performance. However, in terms of efficiency and use of resources and energy, the need is now felt to develop a simpler system with fewer steps, shorter lines, less energy requirements (curing and e-coat deposition) and less stringent waste disposal requirement (phosphate sludge). We report here on the development of a one-step system that can possibly replace both the zinc phosphate and the e-coating processes. Such a system is based on the so-called superprimer concept that we have recently developed for the replacement of chromate pretreatment and chromate-containing primers in the aerospace industry. With some modifications, such systems can also be adapted for use in the automotive industry.