• Journal of Acupuncture Research
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• v.21 no.5
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• pp.69-78
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• 2004

Objective : This study was undertaken to determine the inhibitory effect of Whallak-tang against Nitric Oxide, the scavenging effect of Whallak-tang on DPPH radical. Methods : Both nitric concentration 1, 3, 6 and 24 hours after treatment with Vit. C and Whallak-tang at 0.1, 1, 10 mg/ml and scavenging effect 10, 20, 30 and 60 minute after treatment with Vit. C and Whallak-tang at 0.1, 1, 10 mg/ml were estimated. Results : The inhibitory effect of Whallak-tang against Nitric Oxide was dose-dependent. The scavenging effect of Whallak-tang on DPPH radical was dose-dependent. Conclusion : These results would provide important basic data on the possibility of the clinical treatment of Whallak-tang in musculoskeletal disease.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.5 no.1
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• pp.125-136
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• 2010

Objectives: The Purpose of this study is to investigate the clinical application of Whallak-tang(Huoluo-tang) to two patients with Whiplash injury. Methods: Patients are hospitalized at Dept. of Oriental Rehabilitation, Bu-Chun Jaseng Oriental Medicine Hospital, diagnosed as Whiplash injury and treated mainly with herbal medine; Whallak-tang(Huoluo-tang). This study was measured by NDI(Neck Disability Index) and VAS(Visual Analogue Scale) score. Results: After taking Whallak-tang(Huoluo-tang), the patient's pain was controlled and slept well after treatment. VAS & NDI score were decreased. Conclusions: As seen in this two cases of whiplash injury, Whallak-tang(Huoluo-tang) has a positive effect to control pain with whiplash injury.

• Journal of Pharmacopuncture
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• v.11 no.4
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• pp.5-14
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• 2008

Objective This study was undertaken to determine the effect of Whallak-tang on expression of CD/cytokine Genes. Methods The expression of CD/Cytokine Genes were examined by cDNA microarray using the human mast cell line(HMC-1). Results The expression of ATP5F1, FLJ20671, unknown, KIAA0342, OAS2, unknown genes were increased in $200{\sim}300%$ range. The expression of unknown, MDS006, IFITM1, MRPL3, ZNF207, FTH1, FBP1, NRGN, NR1H2, KIAA0747 genes were decreased in $0{\sim}33%$ range. Conclusion These results would provide important basic data on the possibility of the clinical treatment of Whallak-tang in musculoskeletal disease.