• International Journal of Internet, Broadcasting and Communication
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• 제13권1호
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• pp.37-46
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• 2021

Recently, social technologies have been created to solve problems from businesses for the establishment of generational solidarity ecosystem in terms of employment, residential space, network and social capital, age, cognitive and environmental aspects. This is senior-friendly healthcare business system aimed at meeting the senior needs for health life to enjoy active consumption culture life even after retirement, becoming a catalyst for minimizing generational conflicts, preventing the cognitive and physical deterioration of seniority in the areas of life healthcare, fitness and well-aging, and expanding into systems necessary for seniority self-reliance. We would like to draw up the development and requirements of the concept of the service platform for the study of collective characteristics for generation solidarity with senior class and the establishment of a customized senior health life system for generation solidarity. This system is characterized by a platform that can prevent the decline of seniors' cognitive and physical functions and enhance emotional stability. It is significant in providing feedback on the risk perception index, fall index, and prevention training index information to the child through the analysis and extraction of the senior health index for risk perception, fall probability, and fall prevention.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2019년도 춘계학술대회
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• pp.281-282
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• 2019

In recent years welfare of animals is the biggest challenge because animals, especially dogs are widely recognized as pet as well as they are using as service animals. So, for the wellbeing of the dog it is necessary to perform objective assessment to track their behavior in everyday life. In this paper, we have proposed an automatic behavior assessment system for dogs based on a neck worn and tail worn accelerometer and gyroscope platform, and data analysis techniques that recognize typical dog activities. We evaluate the system based on the analysis of 8 behavior traits in 3 dogs, incorporating 2 breeds of various sizes. Our proposed framework able to reproduce the manual assessment that is based on the video recording which is treated as gold standard that exhibits the real-life use case of automated dog behavior analysis.

• 한국산학기술학회논문지
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• 제22권5호
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• pp.257-269
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• 2021

본 연구에서는 성공적인 노화를 위한 신체적, 정신적, 사회경제적 측면의 웰에이징 교육 요구를 분석하여 웰에이징 교육 프로그램의 개발 및 운영을 위한 기초자료를 확보하고자 한다. 조사도구는 웰에이징에 관한 인식과 신체적, 정신적, 사회경제적 측면의 웰에이징 교육 요구를 알아보기 위한 문항으로 제작되었다. 2021년 2월 한 달 동안 한국갤럽의 온라인·모바일 조사를 통해 만 19세 이상 성인 1949명을 대상으로 조사하였다. 웰에이징 교육 요구를 분석하기 위해서 기술통계분석, 분산분석, Borich 요구도 분석 및 IPA분석이 실시되었다. 연구결과, 웰에이징을 위한 교육 요구도의 전체 우선순위로 보았을 때 경제력, 운동, 만성질환관리 등이 높게 나타났으며, 교육 요구도가 낮은 순으로는 감염질환관리, 자립심, 사회적 책임으로 조사되었다. 특히 경제력은 전체 응답자의 82.4%에 해당하는 중년기(35~49세)를 제외한 모든 연령대에서 교육 요구도가 가장 높게 나타났으며, 중년기에서는 운동과 만성질환관리의 교육 요구도가 가장 높게 나타나 생애주기별 웰에이징 프로그램이 필요함을 시사하였다. 본 연구의 결과는 웰에이징을 위한 교육 프로그램 개발 및 운영 플랫폼을 구축하는데 실증자료로서 활용될 수 있을 것으로 기대된다.

• Genomics & Informatics
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• 제21권2호
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• pp.23.1-23.9
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• 2023

The mammalian sirtuin family, consisting of SIRT1-SIRT7, plays a vital role in various biological processes, including cancer, diabetes, neurodegeneration, cardiovascular disease, cellular metabolism, and cellular homeostasis maintenance. Due to their involvement in these biological processes, modulating sirtuin activity seems promising to impact immuneand aging-related diseases, as well as cancer pathways. However, more understanding is required regarding the safety and efficacy of sirtuin-targeted therapies due to the complex regulatory mechanisms that govern their activity, particularly in the context of multiple targets. In this study, the interaction landscape of the sirtuin family was analyzed using a systems biology approach. A sirtuin protein-protein interaction network was built using the Cytoscape platform and analyzed using the NetworkAnalyzer and stringApp plugins. The result revealed the sirtuin family's association with numerous proteins that play diverse roles, suggesting a complex interplay between sirtuins and other proteins. Based on network topological and functional analysis, SIRT1 was identified as the most prominent among sirtuin family members, demonstrating that 25 of its protein partners are involved in cancer, 22 in innate immune response, and 29 in aging, with some being linked to a combination of two or more pathways. This study lays the foundation for the development of novel therapies that can target sirtuins with precision and efficacy. By illustrating the various interactions among the proteins in the sirtuin family, we have revealed the multifaceted roles of SIRT1 and provided a framework for their possible roles to be precisely understood, manipulated, and translated into therapeutics in the future.

• 센서학회지
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• 제15권5호
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• pp.362-370
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• 2006

The wireless sensor network (WSN) based ECG and body temperature measuring system for ubiquitous health-care were designed and developed. The system was composed of a wireless sensor network node, base station and server computer for the continuous monitoring of ECG signals and body temperatures of patients at home or hospital. ECG signal and body temperature data, important vital signals which are commonly used in clinical and trauma care, were displayed on a graphical user interface (GUI). The data transfer from sensor nodes on patients' body to server computer was accomplished through a base-station connected to a server computer using Zigbee compatible IEEE802.15.4 standard wireless communication. Real-time as well as historical, ECG data of elderly persons or patients, can also be retrieved and played back to assist the diagnosis. The ubiquitous health care system presented in this study can effectively reduce social medical expenses, which will be increased greatly in the coming aging society.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권3호
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• pp.1362-1376
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• 2016

A cloud computing system can be characterized by the provision of resources in the form of services to third parties on a leased, usage-based basis, as well as the private infrastructures maintained and utilized by individual organizations. To attain the desired reliability and energy efficiency in a cloud data center, trade-offs need to be carried out between system performance and power consumption. Resolving these conflicting goals is often the major challenge encountered in the design of optimization strategies for cloud data centers. The work presented in this paper is directed towards the development of an Energy-efficient and Performance-aware Cloud System equipped with strategies for dynamic switching of optimization approach. Moreover, a platform is also provided for the deployment of a Wind Farm CMS (Condition Monitoring System) which allows ubiquitous access. Due to the geographically-dispersed nature of wind farms, the CMS can take advantage of the cloud's highly scalable architecture in order to keep a reliable and efficient operation capable of handling multiple simultaneous users and huge amount of monitoring data. Using the proposed cloud architecture, a Wind Farm CMS is deployed in a virtual platform to monitor and evaluate the aging conditions of the turbine's major components in concurrent, yet isolated working environments.

• Steel and Composite Structures
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• 제22권3호
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• pp.537-565
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• 2016

Australian railway networks possess a large amount of aging timber components and need to replace them in excess of 280 thousands $m^3$ per year. The relatively high turnover of timber sleepers (crossties in a plain track), bearers (skeleton ties in a turnout), and transoms (bridge cross beams) is responsible for producing greenhouse gas emissions 6 times greater than an equivalent reinforced concrete counterparts. This paper presents an innovative solution for the replacement of aging timber transoms installed on existing railway bridges along with the incorporation of a continuous walkway platform, which is proven to provide environmental, safety and financial benefits. Recent developments for alternative composite materials to replace timber components in railway infrastructure construction and maintenance demonstrate some compatibility issues with track stiffness as well as structural and geometrical track systems. Structural concrete are generally used for new railway bridges where the comparatively thicker and heavier fixed slab track systems can be accommodated. This study firstly demonstrates a novel and resilient alterative by incorporating steel-concrete composite slab theory and combines the capabilities of being precast and modulated, in order to reduce the depth, weight and required installation time relative to conventional concrete direct-fixation track slab systems. Clear benefits of the new steel-concrete composites are the maintainability and constructability, especially for existing railway bridges (or brown fields). Critical considerations in the design and finite element modelling for performance benchmarking of composite structures and their failure modes are highlighted in this paper, altogether with risks, compatibilities and compliances.

• 디지털융복합연구
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• 제17권9호
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• pp.421-428
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• 2019

본 연구는 국내외 여행에서 일어날 수 있는 기존의 문제점 해결과 함께 여행을 기반으로 테마 여행뿐만 아니라 헬스 케어, 전시 공연, 맛집 쇼핑, 비즈니스, 일상생활 등 6가지 전문 안내가 필요한 서비스 군을 포함하며, 사용자들에게 검증된 전문 가이드를 연결해주는 서비스를 제안하는 것이다. 선행 연구 결과, 해외여행 중 가장 필요한 서비스로는 항공권, 숙박, 교통, 가이드 순으로 조사되었으나, 우리나라의 경우 고령화 사회로 진입하면서 전문 가이드 서비스는 필수적 서비스로서 그 수요는 날로 증가할 것으로 예상된다. 이를 토대로 서비스의 기술과 사용자 시나리오 그리고 브랜드 개발을 제시하였다. 본 서비스 제안을 통해 사용자는 기존에 알지 못하던 지식이나 경험을 맞춤형 가이드를 통해 제공받게 되어, 더 풍부한 경험을 할 수 있다. 또한, 가이드로서는 새로운 전문분야를 익히는 데 도움이 되어 전문 가이드의 역량을 향상하는데 도움을 줄 수 있다. 마지막으로 이 플랫폼 서비스는 사용자가 편의를 받을 수 있는 동시에 자신이 가지고 있는 역량을 통해 서비스를 제공할 수 있으므로 누구나 경제활동을 가능케 함으로써 일자리 창출이 가능하다는 데 의의가 있다.

• Genomics & Informatics
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• 제16권2호
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• pp.22-29
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• 2018

Incorporation of unique barcodes into fission yeast gene deletion collections has enabled the identification of gene functions by growth fitness analysis. For fine tuning, it is important to examine barcode sequences, because mutations arise during strain construction. Out of 8,708 barcodes (4,354 strains) covering 88.5% of all 4,919 open reading frames, 7,734 barcodes (88.8%) were validated as high-fidelity to be inserted at the correct positions by Sanger sequencing. Sequence examination of the 7,734 high-fidelity barcodes revealed that 1,039 barcodes (13.4%) deviated from the original design. In total, 1,284 mutations (mutation rate of 16.6%) exist within the 1,039 mutated barcodes, which is comparable to budding yeast (18%). When the type of mutation was considered, substitutions accounted for 845 mutations (10.9%), deletions accounted for 319 mutations (4.1%), and insertions accounted for 121 mutations (1.6%). Peculiarly, the frequency of substitutions (67.6%) was unexpectedly higher than in budding yeast (~28%) and well above the predicted error of Sanger sequencing (~2%), which might have arisen during the solid-phase oligonucleotide synthesis and PCR amplification of the barcodes during strain construction. When the mutation rate was analyzed by position within 20-mer barcodes using the 1,284 mutations from the 7,734 sequenced barcodes, there was no significant difference between up-tags and down-tags at a given position. The mutation frequency at a given position was similar at most positions, ranging from 0.4% (32/7,734) to 1.1% (82/7,734), except at position 1, which was highest (3.1%), as in budding yeast. Together, well-defined barcode sequences, combined with the next-generation sequencing platform, promise to make the fission yeast gene deletion library a powerful tool for understanding gene function.

• 한국지리정보학회지
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• 제25권1호
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• pp.77-100
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• 2022

저성장·고령화시대에 접어들면서 지방의 많은 도시들이 인구감소문제를 경험하고 있다. 생산인 력감소, 재정감축, 삶의 질 저하, 공동체 기반 붕괴 등 다양한 형태의 쇠퇴현상들이 연쇄적으로 발생하면서 지방소멸의 벼랑 끝으로 몰리고 있다. 본 연구는 저성장·고령화 시대 인구감소도시의 효율적인 공간관리 정책으로써 컴팩시티 계획을 적용하기 위해 공간통계기법과 GIS를 활용하여 도시 내 고용창출중심지 추정과 고용 권역을 설정하는 방법론을 제안하였다. 구체적으로 컴팩시티에 관한 선행연구 검토를 통하여 종사자수, 정주인구수, 개발용지 면적을 고려한 새로운 지표 '고용복합지수'를 정의하고, 국지적 모란지수와 핫스팟 분석을 적용하여 고용창출중심지를 추정하였다. 창원시를 대상으로 2013년, 2015년, 2017년, 2019년의 4개 년도를 사례분석을 실시하여 고용창출중심지의 압축된 다핵구조를 확인하였다. 이 결과를 바탕으로 지속적 도시 성장을 위한 산업중심 권역 설정과 컴팩시티 공간정책의 시사점을 제시하였다. 본 분석 결과는 지역활성화 플랫폼을 위한 기능적·제도적 권역 거버넌스의 기초자료로써 인구감소, 지역총생산, 에너지 절감에 대응할 수 있는 공공시설배치, 교통계획, 의료보건 계획 등 공간정책 의사 결정에 필요한 유의미한 정보를 제공할 수 있을 것으로 기대한다.