• 비교문화연구
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• 제48권
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• pp.67-106
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• 2017

이 논문은 중국에서 중국어로 집필된 한국문학사 가운데 조선족 학자인 이암(李岩)(외)의 "조선문학통사"(2010)와 한족 학자인 위욱승(韋旭昇)의 "조선문학사"(1988, 2008)의 서술시각을 남북한문학사와 비교하여 그 특징을 밝히고자 하였다. 주요 검토 결과는 다음과 같다. 첫째, 조동일의 "한국문학통사"와 북한 15권본에서는 시대구분 방식, 장르의 개념, 개별 작품에 대해 논의를 세밀하게 전개하면서 이를 문학사 서술에서 적극 활용한 바 있다. 그러나 위욱승(韋旭昇)과 이암(李岩)의 한국문학사에서는 남북한의 이러한 이론적 논의 과정에 거의 주목하지 않았다. 이암(李岩)의 "조선문학통사"는 2010년에 출간되었고, 위욱승(韋旭昇)의 "조선문학사"는 1986년 초판을, 2000년과 2008년에 개정판을 출간했다. 두 문학사의 출간 시점으로 보면, 한국쪽에서 이루어진 여러 논의들을 참조하는 것이 당연한 일일 터인데 그렇지 못하다. 자국문학사의 서술 전통에 더 많은 영향을 받았기 때문이라 생각된다. 둘째, 두 텍스트는 정치 사회 경제 문화 등 문학 외부적 요인을 중시하며 각 시대마다 '개술'에서 이를 따로 언급하고 있고, 본문에서도 인민성 현실성 민족성 등 '정치 표준'에 의거한 평가가 중시된다. 이는 사회주의 체제에서의 문학사 서술에서 자주 쓰이는 방식이며, 북한 15권본도 비슷한 형식을 보인다. 셋째, 두 문학사는 중국학자가 쓴 한국문학사이기 때문에 중국문학과 한국문학의 연관성에 주목하는 부분이 많다. 하지만 소품(小品) 낙부(樂府) 우언(寓言) 설창(說唱) 사전(史傳) 등 장르 용어는 중국문학 용어를 많이 활용하였다. 그러나 중국에서 사용되는 이러한 장르 용어로 한국문학을 설명할 때, 본래의 의미와 변화된 의미 사이의 차이를 세밀하게 검토하지 않은 경우가 많았다. 향후 작업에서 반드시 고려되어야 할 점이라 생각한다.

• Journal of Microbiology and Biotechnology
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• 제24권10호
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• pp.1421-1426
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• 2014

Although a large number of AroA enzymes (EPSPS: 5-enopyruvylshikimate-3-phosphate synthase) have been identified, cloned, and tested for glyphosate resistance, only two AroA variants, derived from Agrobacterium tumefaciens strain CP4 and Zea mays, have been utilized to produce the commercial glyphosate-resistant crops. Here, we have used a PCR-based twostep DNA synthesis method to synthesize an aroA gene ($aroA_{A.\;metalliredigens}$) from Alkaliphilus metalliredigens, encoding a new EPSPS. Furthermore, transgenic Arabidopsis with the new $aroA_{A.\;metalliredigens}$ gene was obtained to confirm the potential of the novel aroA gene in developing glyphosate-resistant crops.

• 전기학회논문지
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• 제66권1호
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• pp.61-65
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• 2017

In this paper a prototype of high frequency heating power supply system based on the high frequency heating principle is designed to take the place of acupuncture, moxibustion, warm dressing treatment and some other traditional physical therapy methods. Which possess the advantages of low cost, convenient, easy operation and good effect. The high frequency heating power supply can generate a pulse voltage of more than 1KV with 300KHz switching frequency to heat the patient's skin. The skin temperature can reach to $41{\sim}42^{\circ}C$. The peak current control method is used to maintain the skin temperature in the designed range. The design of the main circuit is based on the flyback converter topology. An easier and practical design method is proposed in this paper. The power supply system prototype is verified to be stable and reliable by both the simulation and experimental results.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1998년도 Proceedings of UNESCO-internetwork Cooperative Regional Seminar and Workshop on Bioassay Guided Isolation of Bioactive Substances from Natural Products and Microbial Products
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• pp.62-65
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• 1998

• Asian Pacific Journal of Cancer Prevention
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• 제15권12호
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• pp.4865-4869
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• 2014

Objective: This study evaluated the expression level of high mobility group box-B1 (HMGB-1) and matrix metalloproteinase-9 (MMP-9) in non-small cell lung cancer (NSCLC) inmorder to reveal any relation with development and prognosis. Methods: NSCLC and normal tissues were selected from 30 patients at age of 30-73, and used for RT-PCR and Western blot analyses of HMGB-1. A total of 100 paraffin embedded NSCLC tissues were also isolated from patients through surgical resection, and used for detection of HMGB-1 by immunohistochemistry. In addition, 50 samples were also applied for MMP-9 detection, and 30 normal tissues were considered as controls. Correlation analysis of HMGB-1 and MMP-9 was carried out by Pearsons correlation coefficient. Results: The average expression level of HMGB-1 in NSCLC patients was significantly higher than in normal lung tissues. In addition, patients in III-IV period exhibit significantly higher positive rate of HMGB-1 when compared with I-II period cases. Furthermore, a positive correlation with HMGB-1 was found in the expression of MPP-9. Conclusion: HMGB-1 was highly expressed in NSCLC, which may become a prognostic and predictive marker for NSCLC. Besides, MPP-9 was positively correlated with HMGB-1.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5415-5420
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• 2012

The aim of this study was to investigate QoL (quality of life) of patients with esophageal cancer in northern Henan province, China, and to accurate evaluate and reflect the relationship between patient characteristics and QoL. In the high risk area of esophageal cancer in the north of Henan province, 735 patients with esophageal cancer were investigated. The Eysenck personality questionnaire (EPQ) and QoL were analyzed by using the questionnaire of general situation, EPQ, QLQ-C30 and QLQ-OES18. The effects of personal character on the QoL of esophageal carcinoma patients were analyzed by SPSS 11.0 software. The QoL of esophageal cancer patients in Northern Henan region was significantly affected by character. The difference between choleric and type of melancholic temperament types was significant (P<0.01), also in OESEAT, OESTA, OESCO and OESSP (P<0.05). Differences in personal character can thus influence the quality of esophageal cancer patient lives.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6441-6446
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• 2012

Background: Radiation therapy plays an important role in lung carcinoma treatment. However, the incidence of symptomatic radiation-induced lung injury is high. This study aimed to evaluate radioprotective effects of flavonoids extracted from Astragalus complanatus and mechanisms of action against radiation damage. Methods: Alteration in antioxidant status and levles of several cytokines were investigated in BABL/C mice treated with 4 mg/kg b.wt. flavonoids after exposure to 10Gy thoracic radiation. Results: Serum levels of SOD in the flavonoids+radiation group were significantly higher compared to the radiation control group, while TGF-${\beta}1$ and IL-6 were lower. Mice in the radiation control group displayed more severe lung damage compared with the flavonoids+radiation group. The expression of TGF-${\beta}1$ and TNF-${\alpha}$ in the radiation control group was markedly increased in alveolar epithelial cells and macrophages of the alveolar septum. Conclusions: From the results of the present study, flavonoids could be excellent candidates as protective agents against radiation-induced lung injury.

• Geomechanics and Engineering
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• 제28권2호
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• pp.171-180
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• 2022

Time-dependent stress-strain behaviour significantly influences the compressibility characteristics of the clayey soil. In this paper, a series of oedometer tests were conducted in two loading patterns and investigated the time-dependent compressibility characteristics of Indian Montmorillonite Clay, also known as black cotton soil (BC) soil, during loading-unloading stages. The experimental data are analyzed using a new non-linear function of the Elasto-Visco-Plastic Model considering Swelling behaviour (EVPS model). From the experimental result, it is found that BC soil exhibits significant time-dependent behaviour during creep compared to the swelling stage. Pore water entrance restriction due to consolidated overburden pressure and decrease in cation hydrations are responsible factors. Apart from it, particle sliding is also evident during creep. The time-dependent parameters like strain limit, creep coefficient and C_αe/C_c are observed to be significant during the loading stage than the swelling stage. The relationship between creep coefficients and applied stresses is found to be nonlinear. The creep coefficient increases significantly up to 630 kPa-760 kPa (during reloading), and beyond it, the creep coefficient decreases continuously. Several parameters like loading duration, the magnitude of applied stress, loading history, and loading path have also influenced secondary compressibility characteristics. The time-dependent compressibility characteristics of BC soil are presented and discussed in detail.

• Asian Pacific Journal of Cancer Prevention
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• 제15권18호
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• pp.7741-7746
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• 2014

Although a number of studies have been conducted on the association between GSTM1 polymorphisms and lung cancer in China, this association remains elusive and controversial. To clarify the effects of GSTM1 polymorphisms on the risk of lung cancer, a meta-analysis was performed in the Chinese population. Related studies were identified from PubMed, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National Knowledge Infrastructure (CNKI), and Chinese Biology Medicine (CBM) up to 5th April 2014. A total of 45 articles (47 studies) including 6,623 cases and 7,865 controls were involved in this meta-analysis. Overall, a significant association (OR = 1.45, 95%CI: 1.32-1.60) was found between the null GSTM1 and lung cancer risk when all studies in Chinese population pooled into the meta-analysis. In subgroup analyses stratified by quality score, geographic area and source of controls, the same results were observed under all the models. This meta-analysis showed that the null GSTM1 may be a potential biomarker for lung cancer risk in Chinese, but further studies with gene-gene and gene-environment interactions are required for definite conclusions.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6681-6686
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• 2013

Background: Fatal adverse events (FAEs) have been reported with sorafenib, a vascular endothelial growth factor receptor kinase inhibitor (VEGFR TKI). We here performed an up-to-date and detailed meta-analysis to determine the overall risk of FAEs associated with sorafenib. Methods: Databases, including PubMed, Embase and Web of Science, and abstracts presented at the American Society of Clinical Oncology annual meetings were searched to identify relevant studies. Eligible studies included randomized controlled trials evaluating sorafenib effects in patients with all malignancies. Summary incidence rates, relative risks (RRs), and 95% confidence intervals (CIs) were calculated for FAEs. In addition, subgroup analyses were performed according to tumor type and therapy regimen. Results: 13 trials recruiting 5,546 patients were included in our analysis. The overall incidence of FAEs with sorafenib was 1.99% (95%CI, 0.98-4.02%). Patients treated with sorafenib had a significantly increased risk of FAEs compared with patients treated with control medication, with an RR of 1.77 (95%CI 1.25-2.52, P=0.001). Risk varied with tumour type, but appeared independent of therapy regimen. A significantly increased risk of FAEs was observed in patients with lung cancer (RR 2.26; 95% CI 1.03-4.99; P= 0.043) and renal cancer (RR 1.84; 95% CI 1.15-2.94; P= 0.011). The most common causes of FAEs were hemorrhage (8.6%) and thrombus or embolism (4.9%). Conclusions: It is important for health care practitioners to be aware of the risks of FAEs associated with sorafenib, especially in patients with renal and lung cancer.