• Title/Summary/Keyword: Weak parts

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A Multidimensional System for Phosphopeptide Analysis Using TiO2 Enrichment and Ion-exchange Chromatography with Mass Spectrometry

  • Cho, Kun;Yoo, Ji-Sun;Kim, Eun-Min;Kim, Jin-Young;Kim, Young-Hwan;Oh, Han-Bin;Yoo, Jong-Shin
    • Bulletin of the Korean Chemical Society
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    • v.33 no.10
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    • pp.3298-3302
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    • 2012
  • Although offline enrichment of phosphorylated peptides is widely used, enrichment for phosphopeptides using $TiO_2$ is often performed manually, which is labor-intensive and can lead to irreproducible results. To address the problems associated with offline enrichment and to improve the effectiveness of phosphopeptide detection, we developed an automated online enrichment system for phosphopeptide analysis. A standard protein mixture comprising BSA, fetuin, crystalline, ${\alpha}$-casein and ${\beta}$-casein, and ovalbumin was assessed using our new system. Our multidimensional system has four main parts: a sample pump, a 20-mm $TiO_2$-based column, a weak anion-exchange, and a strong cation-exchange (2:1 WAX:SCX) separation column with LC/MS. Phosphorylated peptides were successfully detected using the $TiO_2$-based online system with little interference from nonphosphorylated peptides. Our results confirmed that our online enrichment system is a simple and efficient method for detecting phosphorylated peptides.

A Study on the Structural Analysis and Test of an Electric Car-Body (전동차 차체 구조물에 대한 구조해석 및 실험에 관한 연구)

  • 전형용;성낙원
    • Journal of the Korean Society for Precision Engineering
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    • v.15 no.12
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    • pp.28-36
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    • 1998
  • This investigation is the result of a structural analysis by the finite element method and static loading test for the optimal structural design of an electric railway vehicle made of stainless 301L materials. We analyzed the stress and displacement of the existing electric car-body structure for predicting the position of concentrated stress, the flow of stress, rigidity to be occurred in the car-body structure when it is subjected to the vertical load. It was exposed that the side sills and window corners around the bolsters are the weak parts of the electric car-body structure because the bolsters of the electric car-body structure were subjected to the vertical load and dynamic load to be occurred during running. The flow of stress and the cause of stress concentration in the weak zone were studied in order to prevent the concentration of stress and buckling. The rearrangement of the structure and the selection of the beam elements were also carried out for optimum design of the structure.

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The Study on Aging (노화(老化)에 대한 연구(硏究) (황제내경(黃帝內經)을 중심으로))

  • Baek, Sang-Ryong
    • Journal of Korean Medical classics
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    • v.12 no.2
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    • pp.176-183
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    • 1999
  • Each life has its own properties that distinguish one another. With this property, Oriental medicine suggests original diagnosis and treament. Our process of aging shows typical outline of cycle, i. e. from one's birth to death. Understanding the life cycle of men gives us very good hint to predict one's state of health, possible diseases, characteristics of disease in each term of his/her life cycle. It's because body and mode of diseases change according to age. Aging starts when $\breve{U}$m Essence(陰精)-the essence one receive from parents-dries up or when Deficient Fire(虛火) soars. Parts that compose our body-bones, muscles, flesh, etc.-gradually weaken and worn out as they no longer get support from Yang-Ki(陽氣), In "Yellow Emperor's Classic", aging starts around one's forties when $\breve{U}$m Essence(陰精) is reduced to less than half. However, what is usually accepted is that women start aging from 49 and men 64, regarding significant geriatric disease. As it is mentioned, aging starts with exhaustion of $\breve{U}$m Essence(陰精) which results in soaring Deficient Fire. Main symptoms are weak mental state due to Sin(神) disorder, and weak physical state due to Spleen and Stomacn(脾胃) disorder. Main principle in treating and preventing diseases related to aging is preserving $\breve{U}$m Essence(陰精), as well as fortifying Ki and Blood(氣血). To do this, Lung(肺)-which collects $\breve{U}$m Essence(陰精), and Kidney(腎) stores-which stores $\breve{U}$m Essence(陰精).

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Scientific Conservation of Seodae of the Chuncheon National Museum (국립춘천박물관 소장 서대(犀帶)의 과학적 보존)

  • Park, Seungwon;Kwon, Heehong;Yu, Heisun;Jo, Kyungmi
    • Conservation Science in Museum
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    • v.11
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    • pp.31-42
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    • 2010
  • Here is an introduction of the conservation and making process of Seodae(Rank Belt with A Rhinoceros' Horn) of the Chuncheon National Museum. The seodae has a structure composed of wrapping fabric around a leather frame and decorated with ttidon(an ornament) made of a rhinoceros' horn and a metal frame. The adhesion between leather was weak and separation was taking place, parts of the horn were missing and the fabric was discoloring. Also the metal frame and the metal wire attaching ttidon were severly corroded. Nondestructive analysis was carried out by using a portable x-ray fluorescence spectroscopy to analyze the components of the metal parts. Conservation was carried out by dismantling parts and carrying out conservation process of each one according to material, then the parts were put back together.

A Study on the Physiological Change of EEG by Olfactory Stimulation (후각자극에 의한 뇌파의 생리적 변화에 관한 연구)

  • 이동형;이재훈
    • Science of Emotion and Sensibility
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    • v.6 no.2
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    • pp.29-35
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    • 2003
  • In the oriental medicine, the illness of a human being is treated properly according to the strength and weakness of his/her physical constitution. In other words, the treatment principle of the oriental medicine is to balance the functions of the weak and strong inner parts of the physical constitution which can be classified into five characteristic elements: that is, the wood, fire, earth, mental, and water. An aroma therapy, one of traditional oriental medicine, uses pertinent perfumes to strengthen weak inner parts of the body, too. Although the remedy based on the five elements (in short, five element remedy) has revealed excellent clinical effects so far, it is still believed that the remedy is rather statistical and subjective than scientific. Thus, more systematic research needs to be done to prove it. In this paper, the correlation between perfume and physical constitutions has been formulated by grasping results of EEG through stimulation of lavender oil to both mental-type and fire-type persons. Also, the possibility of application for the five element remedy has been investigated. As a result, we found that the lavender oil helped to make strong gallbladder soften for fire-type individuals and to balance weak liver and strong gallbladder for mental-type persons. This agrees well with the results of the five element remedy practiced in the oriental medicine.

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AN ANALOGUE OF THE HILTON-MILNER THEOREM FOR WEAK COMPOSITIONS

  • Ku, Cheng Yeaw;Wong, Kok Bin
    • Bulletin of the Korean Mathematical Society
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    • v.52 no.3
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    • pp.1007-1025
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    • 2015
  • Let $\mathbb{N}_0$ be the set of non-negative integers, and let P(n, l) denote the set of all weak compositions of n with l parts, i.e., $P(n,l)=\{(x_1,x_2,{\cdots},x_l){\in}\mathbb{N}^l_0\;:\;x_1+x_2+{\cdots}+x_l=n\}$. For any element $u=(u_1,u_2,{\cdots},u_l){\in}P(n,l)$, denote its ith-coordinate by u(i), i.e., $u(i)=u_i$. A family $A{\subseteq}P(n,l)$ is said to be t-intersecting if ${\mid}\{i:u(i)=v(i)\}{\mid}{\geq}t$ for all $u,v{\epsilon}A$. A family $A{\subseteq}P(n,l)$ is said to be trivially t-intersecting if there is a t-set T of $[l]=\{1,2,{\cdots},l\}$ and elements $y_s{\in}\mathbb{N}_0(s{\in}T)$ such that $A=\{u{\in}P(n,l):u(j)=yj\;for\;all\;j{\in}T\}$. We prove that given any positive integers l, t with $l{\geq}2t+3$, there exists a constant $n_0(l,t)$ depending only on l and t, such that for all $n{\geq}n_0(l,t)$, if $A{\subseteq}P(n,l)$ is non-trivially t-intersecting, then $${\mid}A{\mid}{\leq}(^{n+l-t-l}_{l-t-1})-(^{n-1}_{l-t-1})+t$$. Moreover, equality holds if and only if there is a t-set T of [l] such that $$A=\bigcup_{s{\in}[l]{\backslash}T}\;A_s{\cup}\{q_i:i{\in}T\}$$, where $$A_s=\{u{\in}P(n,l):u(j)=0\;for\;all\;j{\in}T\;and\;u(s)=0\}$$ and $$q_i{\in}P(n,l)\;with\;q_i(j)=0\;fo\;all\;j{\in}[l]{\backslash}\{i\}\;and\;q_i(i)=n$$.

REMARKS ON SIMPLY k-CONNECTIVITY AND k-DEFORMATION RETRACT IN DIGITAL TOPOLOGY

  • Han, Sang-Eon
    • Honam Mathematical Journal
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    • v.36 no.3
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    • pp.519-530
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    • 2014
  • To study a deformation of a digital space from the viewpoint of digital homotopy theory, we have often used the notions of a weak k-deformation retract [20] and a strong k-deformation retract [10, 12, 13]. Thus the papers [10, 12, 13, 16] firstly developed the notion of a strong k-deformation retract which can play an important role in studying a homotopic thinning of a digital space. Besides, the paper [3] deals with a k-deformation retract and its homotopic property related to a digital fundamental group. Thus, as a survey article, comparing among a k-deformation retract in [3], a strong k-deformation retract in [10, 12, 13], a weak deformation k-retract in [20] and a digital k-homotopy equivalence [5, 24], we observe some relationships among them from the viewpoint of digital homotopy theory. Furthermore, the present paper deals with some parts of the preprint [10] which were not published in a journal (see Proposition 3.1). Finally, the present paper corrects Boxer's paper [3] as follows: even though the paper [3] referred to the notion of a digital homotopy equivalence (or a same k-homotopy type) which is a special kind of a k-deformation retract, we need to point out that the notion was already developed in [5] instead of [3] and further corrects the proof of Theorem 4.5 of Boxer's paper [3] (see the proof of Theorem 4.1 in the present paper). While the paper [4] refers some properties of a deck transformation group (or an automorphism group) of digital covering space without any citation, the study was early done by Han in his paper (see the paper [14]).

Musical Score Recognition Using Hierarchical ART2 Algorithm (Hierarchical ART2 알고리즘을 이용한 악보 인식)

  • Kim, Kwang-Baek;Woo, Young-Woon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.10
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    • pp.1997-2003
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    • 2009
  • Methods for effective musical score recognition and efficient editing of musical scores are demanded because functions of computers for researches on musical activities become more and more important parts in recent days. In the conventional methods for handling musical scores manually, there are weak points such as incorrect score symbols in input process and requirement of much time to adjust the incorrect symbols. And also there is another weak point that the scores edited by each application program can be remodified by a specific application program only. In this paper, we proposed a method for automatic musical score recognition of printed musical scores in order to make up for the weak points. In the proposed method, staffs in a scanned score image are eliminated by horizontal histogram, noises are removed by 4 directional edge tracking algorithm, and then musical score symbols are extracted by using Grassfire algorithm. The extracted symbols are recognized by hierarchical ART2 algorithm. In order to evaluate the performance of the proposed method, we used 100 musical scores for experiment. In the experiment, we verified that the proposed method using hierarchical ART2 algorithm is efficient.

Literature Review on Exercise Therapy by Sasang Constitution through Database Search (사상체질별 운동요법 관련 연구 문헌 고찰 - 데이터베이스 검색을 통해 -)

  • Shin, Soyi;Lee, Junhee
    • Journal of Sasang Constitutional Medicine
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    • v.33 no.3
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    • pp.29-53
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    • 2021
  • Objective The purpose of this review was to investigate exercise therapy by sasang constitution and to offer information for further research. Method The literature was investigated from KMBASE, KISS, ScienceON, JSCM, DBpia, Pubmed. The searching term were sasang, sasang constituion, sasang type, taeyangin, taeeumin, soyangin, soeumin, exercise, physical therapy, physical activity, and so on. Studies were extracted and analyzed exercise by sasang constitution, in addition, were also collected physiological differences related to sasang constitution, exercise ability, exercise response and effects, and exercise contraindications. Result & Conclusion It is helpful for Taeyangin to lower the energy through exercises that train the lower body and deep breathing, and there is no need to exercise excessively. Taeeumin tend to be obese compared to other constitutions. In order to be physically healthy, it is good to sweat a lot through regular exercise. It is good to do aerobic exercise that burns a lot of calories every day. Soyangin has a weak lower body, so it is good to exercise to reinforce the lower body. Soyangin has weak stamina, and since static exercise easily loses interest, it is helpful to do exciting exercise, and it can be performed at normal intensity. Soeumin are statistically less physically active. So soeumin need to improve exercise habits, but because physical strength is on the weak side, it is more appropriate to do an exercise that activates the body parts evenly rather than a strong one.

Design of 8 Channel Insertional pTx Array Coil for 3T Body Imaging (8 채널 삽입형 3T Body pTx Array 코일 설계)

  • Kim, Young Beom;Ryu, Yeunchul
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.63 no.4
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    • pp.546-550
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    • 2014
  • In this research, we report all the elements are placed in the space above the patient table as a transmit coil to give optimized B1+ field for the body object. Through the simulations, we compared upper-and-lower parts combined 8 channel Tx array to upper only 8 channel Tx array and showed the utilities of B1+ shimming in multi-channel Tx body imaging at 3T. Half-cylinder shaped upper array shows weak B1+ field area around back of patient without B1+ shimming. After B1+ shimming, highly induced SAR places occurred in the arm region due to the close distance to the both end elements which were driven by very high RF current to enhance B1+ in back area. The proposed upper and lower combined array provides an enhanced homogeneous B1+ field in large ROI imaging as a result of shimming over the body size phantom. Through this research we proved the usefulness of the proposed insertional upper and lower parts combined transmit array for 3T body imaging.