• 제목/요약/키워드: We Start

검색결과 1,923건 처리시간 0.03초

Effects of Base Changes at the Transcription Start Site on Stringent Control of rnpB in Escherichia coli

  • Choi, Hyun-Sook;Park, Jeong Won;Hong, Soon Kang;Lee, Kangseok;Lee, Younghoon
    • Molecules and Cells
    • /
    • 제26권2호
    • /
    • pp.212-215
    • /
    • 2008
  • The GC-rich discriminator sequence between the -10 region and the transcription start site of the rnpB promoter is responsible for stringent control of M1 RNA synthesis. The rnpB promoter also contains a G nucleotide at the previously identified transcription start site. In this study, we examined by mutagenesis of G to A whether this +1G nucleotide is involved in the stringent response. We found that the change did not alter the stringent response. Since the +1 mutation might alter transcription initiation, we compared the transcription start sites of the wt and mutant promoters by primer extension analysis. Surprisingly, we found that wild type rnpB transcription starts at both the +1G position (70%) and the -1C position (30%), and that the +1A mutation led to transcription initiation exclusively at the -1C position. We also generated two transversion mutations at the -1 position, both of which led to transcription starting exclusively at that position. The -1G mutant promoter gave a stringent signal similar to the wild-type, whereas the -1A mutant generated a significantly less stringent signal. Base on these results, we propose that a short sequence, up to 7 bp downstream of the -10 region, is involved in the stringent response of the rnpB promoter.

업종별 창업 및 폐업의 지리적 특성 분석 (Geographical Characteristics of Business Start-up and Closing Business according to the Type of Industry)

  • 이금숙;박소현
    • 한국경제지리학회지
    • /
    • 제22권2호
    • /
    • pp.178-195
    • /
    • 2019
  • 본 연구에서는 창업과 폐업을 지리적 맥락에서 검토한다. 특히 업종에 따라 창업과 폐업의 지리적 특성을 밝히고 이들에 작용하는 지리적 요소 및 그 영향을 파악한다. 이를 위하여 창업에 대한 자료 수합이 이루어지는 지역단위인 전국의 시 군 구를 대상으로 지금과 같은 경제상황의 단초가 마련된 금융위기 이후 10년의 자료를 활용한다. 먼저 창업과 폐업의 지리적 특성을 파악하기 위해 개인 및 법인의 공간적 분포 양상을 검토하고, 이들의 지리적 분포를 설명하는 일반선형회귀모형과 공간회귀모형을 구축한다. 분석결과, 창업 입지분포를 결정하는 요인과 폐업에 영향을 미치는 요인이 개인과 법인 간, 개인의 창업과 폐업 간에 다소 상이함을 알 수 있었다. 본 연구결과는 창업을 독려하여 일자리을 창출하고 지역경제를 활성화시키고자하는 국가 및 지방정부의 지역계획에 기초적 자료가 될 것이다.

통전전류 특성을 이용한 모터 기동용 전해 커패시터 폭발 방지 방법 (The Explosion Prevention Method for Electrolytic Motor Start Capacitors using Current Characteristic)

  • 김재현;박진영;박광묵;방선배;김용운
    • 전기학회논문지
    • /
    • 제66권12호
    • /
    • pp.1836-1843
    • /
    • 2017
  • In this paper, we investigated fire cases those are believed to be caused by explosion of a electrolytic motor start capacitor. Using two types of commercially available electrolytic motor start capacitors, capacitor current and the possibility of capacitor explosion were tested. And the ignition possibility of the internal material leaked from a capacitor was also tested. In addition, experiments were conducted to see if the fire could spread when a capacitor was exposed to an external flame. From our test we observed that the current of the electrolytic motor start capacitor rose continuously to a certain level by product, if the capacitor was continuously energized with working voltage, and then the capacitor was exploded. The gas and liquid leaked from the capacitor by the explosion could ignite by an electric arc and an external flame. The capacitor current at explosion was different product by product, but each product had a certain current level at explosion. And the increase rate of the capacitor current until explosion was 24% and 31% for the products used in the experiment. We proposed the capacitor explosion prevention method that cuts off power when the capacitor current rises to a certain threshold level. The proposed method can be used if the current of the applied electrolytic motor start capacitor rises continuously and then the capacitor is exploded at a certain current level when the capacitor is energized continuously.

IPA분석을 통한 창업보육센터 입주기업의 지원 방향 도출에 관한 연구 (A Study on the Support Direction for Start-up Company in Incubation Center through IPA Analysis: Focusing on the Youth Cube in Ansan)

  • 권형은;한창희
    • 산업경영시스템학회지
    • /
    • 제46권4호
    • /
    • pp.124-132
    • /
    • 2023
  • In order to support start-ups effectively with limited resources, it is necessary to provide support tailored to start-up companies. Businesses that are operating in local incubation centers may have different demands for the support depending on the region characteristics. This study was worked on companies that have entered into the incubation center 'Youth Cube', which is operated by Ansan City. We investigated the perception of importance in the field of support to identify support policy priorities, and the satisfaction level of each field of support currently supported. Then We conducted an IPA analysis to derive the direction of support. The Ansan area has regional characteristics that it is located in the metropolitan area with well-equipped start-up infrastructure and many innovative institutions, As a result of the importance survey, technology commercialization was recognized as the most important, and education/mentoring was recognized as the least important. Satisfaction with the space and facilities that can be used free of charge was the highest, and the satisfaction was the lowest for entrepreneurship education/mentoring, as was the degree of importance. In addition, according to each quadrant, we derived support that should be maintained, support that should be intensively improved, support that should be given a low policy priority, and support directions that should be kept in mind to avoid excessive support.

양자 컴퓨팅 환경에서의 Ascon-Hash에 대한 Free-Start 충돌 공격 (A Quantum Free-Start Collision Attack on the Ascon-Hash)

  • 조세희;백승준;김종성
    • 정보보호학회논문지
    • /
    • 제32권4호
    • /
    • pp.617-628
    • /
    • 2022
  • Ascon은 2015년부터 진행되고 있는 NIST 경량암호 공모사업의 최종 라운드 후보 중 하나이며, 해시 모드 Ascon-Hash와 Ascon-Xof를 지원한다. 본 논문에서는 Ascon-Hash의 충돌 공격을 위한 MILP 모델을 개발하고, 해당 모델을 통해 양자 컴퓨팅 환경에서 활용 가능한 차분 경로를 탐색한다. 또한, 탐색한 차분 경로를 이용하여 양자 컴퓨터를 사용할 수 있는 공격자가 3-라운드 Ascon-Hash의 양자 free-start 충돌쌍을 찾을 수 있는 알고리즘을 제시한다. 본 공격은 Ascon-Hash에 대한 충돌 공격을 양자 컴퓨팅 환경에서 최초로 분석했다는 점에서 유의미하다.

모터링 시동 및 시동정지 사이클에서 경사진 축을 갖는 저어널 베어링의 마모 해석 - Part I: 마모발생 가능영역에서의 유막 변화 연구 (Wear Analysis of Journal Bearings in a Misaligned Shaft During Motoring Start-up and Coast-down Cycles - Part I: Study on the Change in Oil Film Thickness at Potential Wear Regions)

  • 전상명
    • Tribology and Lubricants
    • /
    • 제33권4호
    • /
    • pp.153-167
    • /
    • 2017
  • The aim of this study is to find the change in trend in the eccentricities of two journal bearings supporting the crankshaft of a single cylinder engine and the degree of misalignment of the shaft. We analyze the change in oil film thickness considering the wear scar under mixed-elasto-hydrodynamic lubrication regime at potential wear regions. For this, we first calculate the central eccentricities of the two journal bearings by using the mobility method. Then we calculate the outer end eccentricity by using the geometry of the bearings. Further, the tilting angle and degree of misalignment of the shaft are calculated by using the eccentricities of the two bearings. We show that the eccentricity of bearing #1, on which higher load is applied, increases at the beginning of the start-up cycle and during the coast-down cycle. However, the eccentricity of bearing #2, on which lower load is applied, decreases at the beginning of the start-up cycle and increases during the coast-down cycle. From the results of the analysis of oil film thickness, we show that the mixed-elasto-hydrodynamic lubrication regime for a misaligned shaft is at the initial stages of the start-up cycle for both bearing #1 and #2 and at the final stage of the coast-down cycle for only bearing #1.

기동과 효율을 고려한 단상 LSPM의 베리어 설계에 관한 연구 (A study on the Barrier Design Considering Start performance and Efficiency in Single-phase Line-start Permanent Magnet Motor)

  • 김원호;이주
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2008년도 춘계학술대회 논문집 전기기기 및 에너지변환시스템부문
    • /
    • pp.19-21
    • /
    • 2008
  • The purpose of this paper is the optimal design of a single-phase LSPM(Line-Start Permanent Magnet Motor). A single-phase LSPM has a permanent magnet in the rotor that is same as induction motor. For that reason, magnet is operated by breaking torque in starting region and alignment torque in driving region. Therefore, we need the design process considering the trade-off relationship. In this paper, we propose the design process of a single-phase LSPM for a high starting torque and efficiency with equivalent circuit and FEM. And we use Taguchi Method for considering tolerance in manufacture. Finally, we compared the LSPM that is designed in this paper and conventional induction motor.

  • PDF

단상 유도형 동기전동기의 회전자 설계에 관한 연구 (A study on the Rotor Design in Single-phase Line-start Permanent Magnet Motor)

  • 김원호
    • 조명전기설비학회논문지
    • /
    • 제28권1호
    • /
    • pp.29-35
    • /
    • 2014
  • The purpose of this paper is the rotor design of a single-phase LSPM(Line-start permanent magnet) motor. A single-phase LSPM motor has a permanent magnet in the rotor that is same as induction motor. For that reason, magnet is operated by breaking torque in starting region and alignment torque in driving region. Therefore, we need the design process considering the trade-off relationship. In this paper, we propose the design process of a single-phase LSPM motor for a high starting torque and efficiency with FEM. And we use Taguchi Method for considering tolerance in manufacture. Finally, we compared the LSPM motor that is designed in this paper and conventional induction motor.

ICT융합 유형별 스타트업 기업의 성공요인에 관한 연구 -사례연구를 중심으로- (A study on the success factors of ICT Convergence type-specific start-up enterprise - mainly the case study -)

  • 이서한;노승훈
    • 디지털융복합연구
    • /
    • 제12권12호
    • /
    • pp.203-215
    • /
    • 2014
  • 창업에 관한 많은 연구들이 있지만 ICT융합 스타트업 기업을 대상으로 하는 연구는 거의 없다. 본 연구에서는 급속히 성장하고 있는 ICT융합분야에서 스타트업 기업을 대상으로 성공요인을 분석하고자 한다. 10개의 성공한 스타트업 기업의 사례를 바탕으로 ERIS모델을 활용하여 총 29가지의 성공요인을 도출하였다. ICT융합 사업화 형태를 소프트웨어 R&D 중심, 소프트웨어 마케팅 중심, 소프트웨어와 하드웨어를 결합한 R&D 중심, 소프트웨어와 하드웨어를 결합한 마케팅 중심으로 구분하였다. 성공요인 가운데 창업자와 연관된 역량이 가장 많았으며 전문적인 지식, 패러다임 속에서 사업기회의 포착 등을 들 수 있다. ICT융합이라는 기존의 스타트업 기업과 다른 형태의 사업화 과정에서 나타난 성공요인을 도출하였으며 스타트업 기업을 4가지 형태로 유형화하는 데 기여하였다.

Supervised Learning-Based Collaborative Filtering Using Market Basket Data for the Cold-Start Problem

  • Hwang, Wook-Yeon;Jun, Chi-Hyuck
    • Industrial Engineering and Management Systems
    • /
    • 제13권4호
    • /
    • pp.421-431
    • /
    • 2014
  • The market basket data in the form of a binary user-item matrix or a binary item-user matrix can be modelled as a binary classification problem. The binary logistic regression approach tackles the binary classification problem, where principal components are predictor variables. If users or items are sparse in the training data, the binary classification problem can be considered as a cold-start problem. The binary logistic regression approach may not function appropriately if the principal components are inefficient for the cold-start problem. Assuming that the market basket data can also be considered as a special regression problem whose response is either 0 or 1, we propose three supervised learning approaches: random forest regression, random forest classification, and elastic net to tackle the cold-start problem, comparing the performance in a variety of experimental settings. The experimental results show that the proposed supervised learning approaches outperform the conventional approaches.