• 한국환경복원기술학회지
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• 제15권3호
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• pp.45-54
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• 2012

This study intended to analyze growth condition of each object by protected tree's ground for 45 places registered to Pyeongtaek protected tree list in locational characteristics, conduct exchange analysis for impediment extent rate in crown area and tree type to the result and suggest the measures to manage artificial impediment which is an effect on protected tree condition. In this study, the tree whose area of impediment for crown area is less than 21% is tree condition of grade 1~2, less than 21~50% is grade 2~3 and more than 50% is grade 3~5. The more impediment is, the more inconvenience causes on growth and development. So, it verified that the area rate must maintain less than 21% for the root system management of protected tree. For the standard of managing artificial impediment which is an effect on the tree condition of protected trees, the below matters intend to be suggested. The first, the impediment in crown area should be less than 21%. But, if there is not artificial impediment out of crown area, the rate of impediment area is considered to increase somewhat. The second, growth space of protected tree should be maintained by crown area at least and impediment should be established out of the crown area. The third, during the national project and land development, surroundings of protected tree must be applied as park, resting place, etc. and the establishment area of impediment (artificial impediment and natural impediment) in crown area must be limited. The forth, publicity for regional people (especially, land owner) is necessary for the protection of natural inheritance and the value of dependence on local government and village which are the subject of management must be announced widely through the internet media, etc, so its importance must be recognized. The fifth, the matters related to protected tree management must be able to limit artificial damage which is for surroundings of protected tree through the mutual connection among the local governments; construction, civil engineering, architecture, water and sewage, agriculture and forest and others. Also, following studies on the effects of kinds, thickness, etc. of impediment around the protected tree on trees should be continued.

• 수산해양기술연구
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• 제52권3호
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• pp.241-247
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• 2016

The trawl fishery is an important fishery accounting for around 30.0% of adjacent water fishery production in Korea, and the commercial fishing is associated with high rate of fatal and non-fatal occupational injury. The hazard analysis for the fishermen's safety of offshore trawler was conducted to serve as basic data for improving the healthy and safe working environment of fishermen using fishermen's occupational accidents of the national federation of fisheries cooperatives (NFFC) from 2012 to 2014 (n=464). As a result, the occupational accident occurrence rate of large powered trawl fishery was 241.4‰ in east sea trawl fishery, 6.9 times the rate of that. In addition, death and missing rate was found to have very serious level management to 97.7‱ in east sea trawl fishery of death at 6.2 times. The accident occurred in 91.7 to 100.0% was happened at sea. The slipping, others and struck by object and son on occurred more frequently in order in the frequency of accident occurrence pattern. However, the occurrence rate of death and missing did not match the frequency of accident pattern. In other words, slipping occurred more frequently while death and missing risk was not high. The fall in the waters was low while death and missing risk was high. The results are expected to help identify and assess safety hazard occurred in offshore trawlers.

• 동의신경정신과학회지
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• 제24권4호
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• pp.419-434
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• 2013

Objectives: The object of this study is to observe the cognition and motor function recovery effects of Joojakwhan (JJW), a traditional Korean poly-herbal formula for treating various neuropsychiatric diseases such as dementia, for the mildly stroke rats, with 60 minutes of reperfusion transient middle cerebral artery occlusion (tMCAO). Methods: In the present study, 125, 250 and 500 mg/kg of JJW were orally administered, once per day for 10 continuous days 2 hours after the tMCAO. The body weight changes, infarct sizes under 2% 2, 3, 5-triphenyl tetrazolium chloride (TTC) stain, sensorimotor functions and cognitive motor behavior tests were serially monitored with cerebral caspase-3 and cleaved poly (ADP-ribose) polymerase (PARP)-immunoreactivities and histopathological changes. The effects of tMCAO on sensorimotor functions were evaluated by using of limb placing and body-swing tests, and the cognitive motor behaviors were also observed with water maze tests. Results: From the results of tMCAO, with marked decreases of body weights, disorders of sensorimotor functions increases the limb placing test scores, and decrease the numbers and percentages of body swings to the ipsilateral sides. The cognitive motor behaviors increases the distances and time to reach the escape platform which included the inhibitions of the decreases with repeated trials that were observed with focal cerebral cortex infarct volumes. In addition, the marked increases of the atrophy, numbers of degeneration, caspase-3- and PARP-immunoreactive cells around peri-infarct ipsilateral cerebral cortex were also observed in tMCAO controls when compared with the sham control rats, respectively. Conclusions: The results obtained from this study suggest that oral administrations of JJW indicate obvious cognitions and motor function recoveries of the rats with tMCAO, mild strokes, which are mediated by neuro-protective effects through known antioxidant effects of components.

• 대한한방내과학회지
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• 제26권1호
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• pp.182-198
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• 2005

Object : This study was designed to research whether the protection and inhibitory effects of cardiovascular diseases in L-NAME induced rat or ECV 304 cell lines through the Cell morphological pattern, Tunel assay, LDH activity, heart rate, blood pressure and immunohistochemistric analysis by Boonsimgieum water extract Methods : Nitric oxide(NO) play an important role in normal and pathophysiological cells including as a messenger molecule, neurotransmitter, microbiocidal agent, or dilator of blood vessels and artheriosclerosis, hypertension, myocardial infarction, respectively. Endothelial cell products can modulate the magnitude of a response to a vasoconstrictor, as evinced by the greater constriction after endothelium removal or NO synthesis blockade. To investigate that Boonsimgieum in the potential contribution of the levels of nitric oxide generated by endothelial nitric oxide synthase (eNOS) and the mechanisms of protection against NG-nitro-L-arginine methyl ester (L-NAME), human ECV 304 cells, which normally do not express eNOS, were expressed by L-NAME. L-NAME stimulated rat or cells were found to be resistant to injury and delayed death following the Boonsimgieum. Inhibition of nitric oxide synthesis abolished the protective effect against L-NAME, thrombin and collagen exposure. Interestingly, such effects have been observed during stimulation with agents such as phenylephrine and KCl on L-NAME mediate rats, were damaged by the NOS inhibitor L-NAME. Result : As the result of this study, In group, the anti-apoptosis and necrosis in the cardiovascular system have a potential capacity for prevented, protected and treating the diseases of cardiovascular system, against the necrosis of rat and ECV 304 cells with Caspase 3 and calpain expression by L-NAME is promoted. Conclusion : these results demonstrate neuroprotective and memory enhancing effects of ZIBU, suggesting its beneficial actions for the treatment of AD.

• Journal of Biosystems Engineering
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• 제28권6호
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• pp.511-516
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• 2003

컴퓨터 시각 기술은 다양한 농작업 생력화에 있어 핵심적인 역할을 해왔다. 비록 컴퓨터 시각 기술이 광범위한 분야에 성공적으로 적용되고 있다고는 하지만 인간의 시각을 통한 인지 능력에 비하면 현재의 컴퓨터 시각 기술은 여전히 매우 미흡한 수준에 있다고 하겠다. 특히, 작업환경이 비구조적이고 가변적인 농작업 환경 하에서의 작업의 생력화는 이러한 기술적 문제를 극복하는 것이 작업의 성패를 좌우하게 된다. 본 논문에서는 원격작업 개념을 도입하여 작업자와 작업기계간의 호환적인 인터페이스를 구축하고 컴퓨터와 인간의 혼합형 의사결정 시스템을 구현하여 기존의 컴퓨터 시각 기술이 갖는 인지 처리 능력의 한계를 극복하는 시스템을 제안하였다. 시설재배에 요구되는 전정, 관수, 방제, 제초, 수확, 운반 등과 같은 다양한 작업들은 작업 대상체에 대한 인식을 바탕으로 수행된다. 특히 가변적인 자연 조명 환경 하에서 수박과 줄기 그리고 잎이 혼재되어 있는 재배현장의 영상으로부터 수박을 추출하여 그 위치 좌표를 산출하는 작업은 기술적으로 매우 어려운 작업이며 수박이 잎과 줄기로 덮혀 있는 경우 더욱 어려워진다. 제안한 개념을 구현하기 위하여 무선으로 수신되는 재배 현장의 수박 영상으로부터 수박을 인식하도록 하였다. 개발한 시스템은 작업자(농민), 컴퓨터 그리고 자동화 작업설비가 상대적으로 수월성을 갖는 기능을 중심으로 역할을 분담하도록 구축하였다 개발 시스템은 크게 무선원격 모니터링 및 작업제어 모듈, 무선원격 영상 획득 및 데이터 송수신 모듈, 작업자와 컴퓨터간의 인터페이스 모듈로 구성하였다 작업자는 RF 송수신 모듈을 통하여 무선으로 획득되어 터치 스크린에 보여지는 영상을 통하여 작업 지시를 하게 되고 이 작업 지시로부터 컴퓨터는 국부 영상처리 시퀀스를 통하여 수박을 추출하고 위치를 산출하게 된다. 개발한 인터페이스 시스템은 가변적이고 복잡한 작업 환경하에서 작업 대상체의 정보를 실시간으로 성공적으로 추출하였다. 제안한 원격작업 인터페이스 시스템은 다양한 생물생산 작업의 생력화를 촉진하는 중심적 역할을 할 것으로 기대된다.

• 한국해안·해양공학회논문집
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• 제28권6호
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• pp.332-349
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• 2016

OLAFOAM은 파동역학의 시뮬레이션을 위하여 $OpenFOAM^{(R)}$을 확장한 강력한 CFD코드이며, $OpenFOAM^{(R)}$은 다양한 분야에서 각각 수치계산의 목적에 대응할 수 있도록 많은 Solver를 제공하고 있다. OLAFOAM의 기본방정식은 VARANS식에 기초하고, 수치기법으로는 유한체적법을 적용하며, 프로그램은 C++로 코딩되어 Linux운영체제에서 실행된다. 본 연구는 OLAFOAM을 이용하여 먼저 1) 단파와 규칙파하 투과성구조물에서 파의 변형, 2) 규칙파하 잠제에 의한 파의 변형 및 3) 흐름하 규칙파의 변형과 연직유속분포에 대해 기존의 각 실험결과와 비교 검토하여 OLAFOAM의 타당성을 검증하였다. 이로부터 지금까지 거의 검토되지 않은 규칙파와 흐름의 공존장에 설치된 투과성잠제에 대해 배후경사면을 불투과성 혹은 투과성으로 고려한 경우 흐름방향 등의 변화에 따른 잠제 주변에서 수위, 파고, 주파수스펙트럼, 쇄파, 평균유속 및 난류운동에너지 등의 변동특성을 면밀히 검토하였다. 결과로부터 흐름방향(순방향과 역방향)에 따른 파고변화는 난류운동에너지와 밀접한 관계를 가지는 것 등을 알 수 있었다.

• 수산해양기술연구
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• 제51권2호
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• pp.188-194
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• 2015

The powered purse seine fishery is an important fishery accounting for 19.4% of adjacent water fishery production in Korea, and the commercial fishing is associated with high rate of fatal and non-fatal occupational injury. The hazard analysis for the fishermen's safety of offshore large powered purse seiner was conducted to serve as a basic data for improving the healthy and safe working environment of fishermen using fishermen's occupational accidents of the national federation of fisheries cooperatives (NFFC) in 2013 (n=583). As a result, the occupational accident occurrence rate of this fishery was 182.6‰ in all industries 30.9 times the rate of that. In addition, death and missing rate was found to have a very serious level management to 25.1‰ in all industries of death of 17.5 times. The accident occurred in 72.3 to 85.8% was happened at sea. The others, slipping and struck by object etc occurred more frequently in order in the frequency of accident occurrence pattern. However, the occurrence rate of death and missing did not match the frequency of accident pattern. In other words, slipping occurred frequently higher while death and missing risk was not high. And the contact with fishing gear and fall in the waters was low while death and missing risk was high. The results are expected to contribute for identification and assessment of safety hazard occurred in offshore large powered purse seiners.

• 생명과학회지
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• 제15권3호
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• pp.374-381
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• 2005

기능성 식품 첨가물 중에서 당 알코올은 최근 그들의 탁월한 기능성이 알려지면서 수요가 증가하고 있다. 당 알코올 중에서, 만니톨$(C_6H_{14}O_6)$은 식품, 화장품, 제약 산업 등에 매우 광범위하게 이용되고 인체에 독성이 없어 미국 FDA에 의하여 GRAS (Generally Recognized As Safe)로 승인이 되어 이에 대한 수요량이 급격히 증가하는 추세이다. 본 연구는 발효 김치에서 분리 된 L. mesenteroides sp. strain JFY 균주를 이용하여 과당으로부터 만니톨 생산을 위한 최적 생물 전환 조건을 확립하기 위한 것이다. 만니톨 생산을 위한 최적 조건들은 pH 6.5, 배양온도 $28^{\circ}C$, 효모 추출물의 농도 $0.5\%$, 과당의 농도는 $10\%$이었고, 이 조건에서 최대 만니톨생산은 31.5g/l이었다.

• 한국환경생태학회지
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• 제31권2호
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• pp.166-173
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• 2017

호암천에 분포하는 둑중개의 형태적 및 개체군의 특징 조사를 2015년 10월과 2016년 4월에 실시를 하였다. 호암천 상류역(경상북도 경주시 양북면 호암리, 대종천 상류)이 둑중개(Cottus koreanus)의 새로운 서식지로 확인되었으며 또한 삼척오십천 이남의 동해로 유입되는 하천에서 처음 발견되었다. 둑중개가 분포하는 범위는 기림사에서 용연폭포에 이르는 약 1.2 km 구간이었으며 수역은 약 $3,600m^2$ 이었다. 개체군 크기는 총 1,656개체, $100m^2$ 당 46개체가 서식하고 있는 것으로 추정되었으며 분포역이 매우 제한적이며 좁았다. 호암천에 서식하는 개체군은 한강 개체군에 비해 머리길이(head length), 배지느러미 길이(VFR-L), 가슴지느러미 길이(PFR-L), 입의 폭(MW) 등이 짧았으며 그 외의 형질은 일치하였다. 전장이 만 1년생은 40~59 mm, 만 2년생은 60~79 mm, 만 3년생은 80 mm 이상으로 추정되었다. 포란수는 239~468개이었으며 평균 361개 이었다. 성숙란의 직경은 $2.6mm{\pm}0.21$(2.3~3.1)로 대란형에 속하였다. 전장과 체중의 관계식은 BW = 0.00001TL3.01로 상수 a는 0.00001을, 매개변수 b는 3.01 이었고, 평균 1.26 이었다.

• 약학회지
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• 제57권4호
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• pp.258-264
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• 2013

Herbal medicine has been traditionally used in Asian countries for a long time. Many pharmacological effects are identified in the herbs and these herbs are believed to be safe for human. However, the safety or adverse effect of some traditional herbal medicines has not been established. We have chosen Cyperi rhizoma based on the Korea Herbal Pharmacopoeia and which have been widely used for an anti-inflammatory effect in Korea. The object of the study was to evaluate safety of Cyperi rhizoma in rats. The aqueous extract of Cyperi rhizoma was prepared according to the standard hot water extraction method of the Korea Pharmacopoeia. In the sub-chronic study, the aqueous extract of Cyperi rhizoma was orally administered once daily as 0, 125, 250, 500, 1000 and 2000 mg/kg/day to male and female F344 rats for 13 weeks. There were no treatment related abnormalities in mortality, clinical signs, food consumption, ophthalmologic examination, hematology, serum chemistry, urinalysis, gross observation, organ weight and histopathologic examination. In conclusion, The NOAEL (No Observed Adverse Effect Level) for Cyperi rhizoma aqueous extract was determined as more than 2000 mg/kg/day in the present experimental condition.