• Title/Summary/Keyword: Water Flux

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Affinity Filtration Chromatography of Proteins by Chitosan and Chitin Membranes: 1. Preparation and Characterization of Porous Affinity Membranes (키토산 및 키틴 막에 의한 단백질의 친화 여과 크로마토그래피: 1. 다공성 친화 막의 제조와 특성 평가)

  • Youm Kyung-Ho;Yuk Yeong-Jae
    • Membrane Journal
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    • v.16 no.1
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    • pp.39-50
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    • 2006
  • Porous chitosan and chitin membranes were prepared by using silica particles as porogen. Membrane preparation was achieved via the following three steps: (1) chitosan film formation by casting an chitosan solution containing silica particles, (2) preparation of porous chitosan membrane by dissolving the silica particles by immersing the film into an alkaline solution and (3) preparation of porous chitin membrane by acetylation of chitosan membrane with acetic anhydride. The optimum preparation conditions which could provide a chitosan and chitin membranes with good mechanical strength and adequate pure water flux were determined. To allow protein affinity, a reactive dye (Cibacron Blue 3GA) was immobilized on porous chitosan membrane. Binding capacities of affinity chitosan and chitin membranes for protein and enzyme were determined by the batch adsorption experiments of BSA protein and lysozyme enzyme. The maximum binding capacity of affinity chitosan membrane for BSA protein is about 22 mg/mL, and that of affinity chitin membrane for lysozyme enzyme is about 26 mg/mL. Those binding capacities are about $several{\sim}several$ tens times larger than those of chitosan and chitin-based hydrogel beads. Those results suggest that the porous chitosan and chitin membranes are suitable in affinity filtration chromatography for large scale separation of proteins.

Recent Changes of Sedimentation Rate in Lake Takkobu, Northern Japan, Determined 210Pb Dating (210Pb 연대측정에 의한 일본 타호부호수의 토사퇴적속도 변화 분석)

  • Ahn, Young Sang;An, Ki-Wan;Lee, Kye-Han;Nakamura, Futoshi
    • Journal of Korean Society of Forest Science
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    • v.103 no.1
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    • pp.80-86
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    • 2014
  • $^{210}Pb$ dating was conducted to examine the influence of land use changes in the forest catchment on lake sedimentation. The Kushiro River, into which Lake Takkobu drains under regular flow conditions, contributed to an increased sedimentation rate in sampling point at the lake outflow because turbid water from the Kushiro River flows back into Lake Takkobu during floods. The elevated sediment flux from the catchment dilutes the $^{210}Pb$ concentration in sampling points at the inflow of the Takkobu River and the lake outflow, which causes fluctuations in the $^{210}Pb$ concentrations in sediment cores. The $^{210}Pb$ dating was estimated using the CRS (Constant rate of Supply) model. The dates by the CRS model in Lake Takkobu profiles were in good agreement with the dates by $^{137}Cs$. Sedimentation rates reconstructed for the past 100-150 years suggested that sedimentation rates increased drastically following land use changes. While a natural sedimentation rate of $0.01-0.03g/cm^2/year$ is observed until the 1880s, whereas lake sedimentation accelerated to $0.03-0.09g/cm^2/year$ following land use changes such as deforestation and channelization, between the 1880s and 1940s. In particular, the sedimentation rates have been associated with deforestation, channelization, agricultural development and road construction, since the 1980s, and these rates were about 9-28 times higher than those under natural conditions, leading to accelerated lake shallowing.

The Effect of Hydroalcoholic Gel System on Skin Permeation of Piroxicam and its Anti-inflammatory Activity (피록시캄의 피부투과 및 소염효력에 대한 알코올성 하이드로겔 시스템의 영향)

  • Ki, Min-Hyo;Shin, Hee-Jong;Lee, Kang-Woo;Kim, Jae-Wook;Kim, Jung-Woo;Hong, Chung-Il
    • Journal of Pharmaceutical Investigation
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    • v.29 no.3
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    • pp.217-225
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    • 1999
  • These studies were designed to determine the effect of hydroalcoholic gel system (lower alkanol concentration: 40-60%) compared to general hydrogel system (lower alkanol concentration: 10-35%) on transdermal delivery of piroxicam and its anti-inflammatory activity. Piroxicam was incorporated into a hydroalcoholic gel and a hydrogel containing polymers, solvents, and cosolvents. The pH of gel was about 6.3-7.3 and the solvent mixtures were composed of water and various concentrations of ethanol (35, 40, 50, and 60%). For the in vitro study, the skin permeation of piroxicam from the gel formulations was investigated using Franz modified diffusion cells fitted with hairless mouse skin. For the in vivo study, the anti-inflammatory activity of hydroalcoholic gel was compared to other commercial products (piroxicam hydrogel and ketoprofen hydrogel) in rat and human. The anti-inflammatory activity was determined using carrageenan induced foot edema model in rat. For the clinical study, it was evaluated from determining efficacy and acceptability with 98 patients suffering from musculoskeletal pain. A novel piroxicam hydroalcoholic gel was successfully formulated in the range of 40-50% of ethanol as solvent, more than 10% of propylene glycol, 5% of $Transcutol^{\circledR}$ and 1 % of benzyl alcohol. The skin permeation of piroxicam using hydroalcoholic gel system was greater than that of general hydrogel system $(flux\;:\;139.1-148.2\;{\mu}g/cm^2/hr\;vs.43.0-84.5 {\mu}g/cm^2/hr)$ in vitro. In carrageenan-induced edema model, the anti-inflammatory activity of hydroalcoholic gel was better than that of piroxicam hydrogel for edema inhibition (75.1 % vs. 62.9%, p

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Effect of Gypsum Application on Reducing Methane (CH4) Emission in a Reclaimed Coastal Paddy Soil (간척지 논 토양 개량제로서 석고처리가 메탄 배출량 저감에 미치는 영향)

  • Lim, Chang-Hyun;Kim, Sang-Yoon;Kim, Pil-Joo
    • Korean Journal of Environmental Agriculture
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    • v.30 no.3
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    • pp.243-251
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    • 2011
  • BACKGROUND: Gypsum($CaSO_4{\cdot}2H_2O$) is known as an ideal amendment to improve soil quality of the reclaimed coastal land. Since gypsum has very high concentration of electron acceptor like ${SO_4}^{2-}$, its application might be effective on reducing $CH_4$ emission during rice cultivation, but its effect has not been studied well. METHODS AND RESULTS: The effect of gypsum on $CH_4$ emission and rice growth characteristics was studied by pot test, which was packed by reclaimed paddy soils collected from Galsa, Hadong, Gyeongnam province. Chemical-grade gypsum was applied in two soils having EC 2.25 and 9.48 dS/m at rates of 0, 0.5, 1.0 and 2.0%(wt/wt). $CH_4$ emission was characterized a week interval by closed chamber method during rice cultivation. $CH_4$ emission rate was significantly decreased with increasing salt accumulation and gypsum application levels. With increasing gypsum application, dissolved ${SO_4}^{2-}$ concentration in the leachate water was significantly increased, which might have suppressed $CH_4$ production in soil. Total $CH_4$ flux was dramatically decreased with increasing gypsum application. In contrast, rice yield was increased with increasing gypsum application and then achieved maximum productivity at 1.0% gypsum application in two soils. CONCLUSION(s): Gypsum is a very good soil amendment to suppress $CH_4$ emission in reclaimed coastal paddy soils, and improve rice productivity and soil properties. The optimum application level of gypsum is assumed at ca. 1% to improve soil productivity with reducing effectively $CH_4$ emission during rice cultivation.

State-of-Arts of Primary Concrete Degradation Behaviors due to High Temperature and Radiation in Spent Fuel Dry Storage (사용후핵연료 건식저장 콘크리트의 고열과 방사선으로 인한 주요 열화거동 분석)

  • Kim, Jin-Seop;Kook, Donghak;Choi, Jong-Won;Kim, Geon-Young
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.16 no.2
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    • pp.243-260
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    • 2018
  • A literature review on the effects of high temperature and radiation on radiation shielding concrete in Spent Fuel Dry Storage is presented in this study with a focus on concrete degradation. The general threshold is $95^{\circ}C$ for preventing long-term degradation from high temperature, and it is suggested that the temperature gradient should be less than $60^{\circ}C$ to avoid crack generation in concrete structures. The amount of damage depends on the characteristics of the concrete mixture, and increases with the temperature and exposure time. The tensile strength of concrete is more susceptible than the compressive strength to degradation due to high temperature. Nuclear heating from radiation can be neglected under an incident energy flux density of $10^{10}MeV{\cdot}cm^{-2}{\cdot}s^{-1}$. Neutron radiation of >$10^{19}n{\cdot}cm^{-2}$ or an integrated dose of gamma radiation exceeding $10^{10}$ rads can cause a reduction in the compressive and tensile strengths and the elastic moduli. When concrete is highly irradiated, changes in the mechanical properties are primarily caused by variation in water content resulting from high temperature, volume expansion, and crack generation. It is necessary to fully utilize previous research for effective technology development and licensing of a Korean dry storage system. This study can serve as important baseline data for developing domestic technology with regard to concrete casks of an SF (Spent Fuel) dry storage system.

Evaluation of Thermal Insulation and Hypothermia for Development of Life Raft (해상 구명정의 단열성능평가 및 저체온증 예측 수치해석 연구)

  • Hwang, Se-Yun;Jang, Ho-Sang;Kim, Kyung-Woo;Lee, Jang-Hyun
    • Journal of Navigation and Port Research
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    • v.39 no.6
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    • pp.485-491
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    • 2015
  • The technology review about risk of hypothermia of victim according to heat transfer characteristic of life raft and sea state can use accident correspondence of standing and sinking of ship. This study studied heat transfer characteristics required for the design of life raft and thermal insulation property analysis and evaluation methods. In addition, it is study for comprehend the risk of hypothermia and suggest analysis result that is experiment of thermal insulation property and body temperature property for decide of prediction the body temperature decline Thermal Analysis apply the finite element analysis method is comprehended the property of heat conductivity, convective effect of sea water and properties changes according to property of insulation material. it measure the heat flux with attach temperature sensor on body in order to comprehend the variation of body temperature with boarding a life raft experiment on a human body. This study validate results by comparing variation of temperature measured from experiment on a body with variation of temperature from finite element analysis model. Also, the criteria of hypothermia was discussed through result of finite element analysis.

Characteristics of Surface Sedment and Seasonal Variation of Suspended Sediment in the Masan Bay, South Coast of Korea (한국 남해 마산만의 표층퇴적물 특성과 부유퇴적물의 계절별 변화 양상)

  • Choi, Jae Ung;Woo, Han Jun;Choi, Dong Lim;Lee, Tae Hee
    • Journal of Wetlands Research
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    • v.8 no.3
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    • pp.67-77
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    • 2006
  • Sedimentological investigations on surface and suspended sediments were performed in Masan Bay of the South Sea in order to reveal recent changes in depositional environments concerning anthropogenic influence. Surface sediments had been classified as 3 sediment facies: mud, slightly gravelly mud, and gravelly mud. In general, mud facies with more than 60% of silt is predominant and slightly gravelly mud facies occurs at the watercourse of bay's central area. The silt-dominant mud faices appears to be predominant before and after dredging. Temperature and salinity changes during one tidal cycle for each season suggest that water columns were stratified without vertical mixing regardless of the season due to weak intensity of tide from the effect of geographical features. The effect of freshwater discharge from the land seems to be insignificant. The strongest current was observed during ebb tide in spring and autumn while observed during flood tide in summer and winter. Net sediment flux (fs) and net suspended sediment transport (Qs) for suspended sediment were determined by remaining drift developed here. Net suspended sediment transport loads were seaward with $62.02{\times}10^3kgm^{-1}$, $31.84{\times}10^3kgm^{-1}$ in spring and fall, respectively, and landward with $18.23{\times}10^3kgm^{-1}$, $3.22{\times}10^3kgm^{-1}$ in summer and winter, respectively.

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The Performance of the Combined Operation of Sprinkler and Smoke Curtain for Smoke Control in the Sloped Stairway Corridor (경사통로로 전파되는 연기에 대한 스프링클러와 제연커텐의 통합제연성능)

  • Jeon, Heung-Kyun;Choi, Young-Sang;Choo, Hong-Lok
    • Fire Science and Engineering
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    • v.20 no.4 s.64
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    • pp.1-12
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    • 2006
  • In this study, CFD computer simulations by FDS are carried out in order to confirm the performance of the combined operation of both sprinkler system and smoke curtain of 0.54 m depth installed for cooling and blocking the smoke which propagates beneath the sloped ceiling of a stairway corridor of which dimensions are 17.92 m long, 4.00 m wide, and 6.12 m high. It is shown that the response time of sprinklers decreases with fire size and it increases more about 1.1 second in case without smoke curtain than in case with smoke curtain, that the time of smoke transport from the fire source to the stairway outlet decreases considerably with fire size, and that the delay effect of smoke transport is not related to the sprinkler system, whether it is operated or not. This study shows that the combined operation of both sprinkler system and smoke curtain is very effective in smoke cooling, but it is a little for effect on smoke blockage. Although the hazard of skin burn due to radiative heat flux from hot smoke layer is decreased by spray cooling effect, the hazard of smoke suffocation and the weakening of visibility is increased by smoke downdrag and the turbulence of smoke-air mixing due to water spray. These conditions may result in preventing occupants from going out of the stairway during evacuation.

Investigation of Convective Heat Transfer Characteristics of Aqueous SiO2 Nanofluids under Laminar Flow Conditions (층류유동 조건에서 SiO2 나노유체의 대류 열전달 특성에 대한 연구)

  • Park, Hyun-Ah;Park, Ji-Hyun;Jeong, Rag-Gyo;Kang, Seok-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.9
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    • pp.1-11
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    • 2016
  • The effect of the migration of nanoparticles near the wall of a channel on the convective heat transfer in a laminar flow of $SiO_2$ nanoparticle suspensions (nanofluids) under constant wall heat flux boundary conditions was numerically and experimentally investigated in this study. The dynamic thermal conductivity of the aqueous $SiO_2$ nanofluids was measured using T-type thermocouples attached to the outer surface of a stainless steel circular tube (with a length of 1 m and diameter of 1.75 mm). The nanofluids used in this study were synthesized by dispersing $SiO_2$ spherical nanoparticles with a diameter of 24 nm in de-ionized water (DIW). The enhancement of the thermal conductivity of the nanofluids (e.g., an increase of up to 7.9 %) was demonstrated by comparing the temperature profiles in the flow of the nanofluids with that in the flow of the basefluids (i.e., DIW). However, this trend was not demonstrated in the computational analysis, because the numerical models were based on continuum assumptions and flow features involving nanoparticles in a stable colloidal solution. Thus, to explore the non-continuum effects, such as the modification of the morphology caused by nanoparticle-wall interactions on the heat exchanging surfaces (e.g., the isolated and dispersed precipitation of the nanoparticles), additional experiments were performed using DIW right after the measurements using the nanofluids.

Preparation of Polysulfone Composite Ultrafiltration Hollow Fiber Membranes Incorporating Nano-size Fumed Silica with Enhanced Antifouling Properties (나노 크기의 Fumed Silica가 함유된 Polysulfone 한외여과 중공사막 제조 및 내오염성 분석)

  • Kang, Yesol;Lim, Joohwan;Kim, In S.
    • Membrane Journal
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    • v.28 no.6
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    • pp.379-387
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    • 2018
  • This study was conducted to improve the membrane characteristics and performance by increasing hydrophilicity by adding additives to the ultrafiltration polysulfone (PSf) hollow fiber membrane. The mixed matrix membranes (MMMs) were prepared by dispersing 15 nm of fumed silica (FS) in the spinning solution at 0.1, 0.3 and 0.5 wt%. SEM analysis was carried out to confirm the cross-section and surface condition. It was confirmed that mean pore radius of the hollow fiber increased by 4 nm as FS was added. In addition, contact angle measurement was carried out for the hydrophilicity analysis of hollow fiber membranes, and it was confirmed that the hydrophilicity of MMMs were increased by adding of FS. In the case of water permeability, the membrane including FS showed 91~96 LMH and showed 5~11% more increase than PSf membrane. In the antifouling performance test, relative flux reduction ratios of FS mixed hollow fiber membranes were lower than that of PSf membranes, and it was confirmed that increase of hydrophilicity hinders adsorption of hydrophobic BSA on the membrane surface.