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Fiber-optic biosensor for the detection of organophosphorus compounds in a contaminated water (Part I. : Design and development) (오염수 내의 유기인 화합물의 측정을 위한 광섬유 바이오센서 (제 1 부 : 장치 설계 및 개발 ))

  • Choi, Jeong-Woo;Min, Jun-Hong;Lee, Won-Hong
    • Journal of Sensor Science and Technology
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    • v.3 no.2
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    • pp.50-56
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    • 1994
  • Fiber-optic biosensor for the detection of organophosphorus compounds in a contaminated water was developed, which was the component of pesticides and agricultural agent. The detection principle of designed sensor was the pH variance induced by a reaction of acetylcholinesterase enzyme inhibited by organophosphorus compounds. The pH variance was detected by the optical system to measure the organophosphorus compounds. Litmus was selected as the pH-sensitive dye suitable to the enzyme reaction and a light source to be detected by the optical system. The enzyme entrapped in Ca-alginate gel was immobilized at the inner wall to maintain the high activity of enzyme and to be reused for a long period. The optical fiber was used to miniaturize and control remotely the sensor system. The He-Ne laser with 632 nm was selected as the light source to prevent light intensity fluctuation by the product. Cheap plastic optical fibers were used as the transmission part of the light and the phototransistor was used as the reception part of light based on the wavelength of He-Ne laser. The proposed fiber-optic biosensor has the linear analytical range of 0 ppm-1.5 ppm with response time of 5 minutes.

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Improvement of Capturing Velocity in the Fume Hood using Computational Fluid Dynamics(I) - Uniform flow (전산유체역학을 이용한 흄후드 제어유속 개선(I) - 균일류)

  • Jung, Jong-Hyeon;Lee, Sang-Woon;Lee, Sang-Man;Shon, Byung-Hyun;Lee, Jung-Hee;Jung, Yu-Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.2
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    • pp.962-969
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    • 2013
  • This study used Computational Fluid Dynamics(CFD) to assess the properties of the air current inflow and the flow velocity distribution in the fume hood. In order to verify the effect of improvement, it was also predicted the characteristics of the flow pattern in case the hood face is structurally improved. The assessment of the capture velocity with the existing fume hood confirmed maximum 23 to 30% difference as compared to the root mean square (RMS). And the hood face showed great difference in flow velocity, with the flow velocity in the upper part is 58 to 68% faster than that in the lower part of the hood. So, as a result of the improvement of the hood designed to maintain a steady exhaust at the hood face (that is, installing a baffle on the inner wall and designing the slot type face), a difference of maximum 7% as compared to RMS appeared while maximum 12% differentiation in flow velocity through sections was predicted, showing mitigation of much of the difference in control velocity as compared to the previous structure.

Bioequivalence of Broadcef Capsule to Cefradine Yuhan Capsule (Cephradine 500 mg) (유한세프라딘 캅셀(세프라딘 500 mg)에 대한 브로드세프 캅셀의 생물학적 동등성)

  • Cho, Hea-Young;Lee, Suk;Kang, Hyun-Ah;Oh, In-Joon;Lim, Dong-Koo;Moon, Jai-Dong;Lee, Yong-Bok
    • Journal of Pharmaceutical Investigation
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    • v.32 no.3
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    • pp.215-221
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    • 2002
  • Cephradine is a first generation cephalosporin and has broad spectrum antibacterial activity against gram-positive and gram-negative microorganisms, through inhibition of bacterial cell wall synthesis. Cephradine is useful for treatment of infections of the urinary and respiratory tract, skin and soft tissues. The purpose of the present study was to evaluate the bioequivalence of two cephradine capsules, Cefradine Yuhan (YuHan Corporation) and Broadcef (Ilsung Pharmaceuticals Co. Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). The cephradine release from the two cephradine capsules in vitro was tested using KP VII Apparatus II method with various different kinds of dissolution media (pH 1.2, 4.0, 6.8 buffer solution and water). Twenty normal male volunteers, $23.10{\pm}2.90$ years in age and $67.69{\pm}8.04\;kg$ in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After one capsule containing 500 mg as cephradine was orally administered, blood was taken at predetermined time intervals and the concentrations of cephradine in serum were determined using HPLC method with UV detector. The dissolution profiles of two cephradine capsules were very similar at all dissolution media. Besides, the pharmacokinetic parameters such as $AVC_t,\;C_{max}\;and\;T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed $AVC_t\;and\;C_{max}$ and untransformed $T_{max}$. The results showed that the differences in $AVC_t,\;C_{max}\;and\;T_{max}$ between two capsules based on the Cefradine Yuhan were -2.87%, -0.96% and -4.85%, respectively. There were no sequence effects between two capsules in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of 1og(0.8) to log(1.25) $(e.g.,\;log(0.93){\sim}log(1.02)\;and\;log(0.88){\sim}log(1.13)\;for \;AVC_t\;and\;C_{max},\;respectively)$. The 90% confidence interval using untransformed data was within ${\pm}20%$ $(e.g., \;-17.54{\sim}7.78\;for\;T_{max})$. All parameters met the criteria of KFDA guideline for bioequivalence, indicating that Broadcef capsule is bioequivalent to Cefradine Yuhan capsule.

A Design of Isoflux Radiation Pattern Microstrip Patch Antenna for LEO Medium-sized Satellites (저궤도 중형급 위성용 isoflux 방사패턴을 갖는 마이크로스트립 안테나 설계)

  • Kim, Jun-Won;Woo, Jong-Myung
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.14 no.2
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    • pp.24-29
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    • 2015
  • In this paper, a microstrip antenna with isoflux radiation patterns is presented for Low Earth Orbit(LEO) medium-sized satellites. Because of making isoflux patterns, the ground of proposed antenna under the patch was transform into a trapezoid for adjusting fringing field between the patch and ground. Next, the cavity walls were located at end of the ground for reducing back radiation. The proposed antenna was designed to receive S-band uplink(2.025 ~ 2.110 GHz) and the dimensions of the designed antenna with the ground are $160mm{\times}160mm{\times}40mm$ ($1.1{\lambda}{\times}1.1{\lambda}{\times}0.3{\lambda}$, ${\lambda}$ is the free-space wavelength at 2.068 GHz). Measured -10 dB bandwidth was 90 MHz(4.4 %) and it covers the required system bandwidth. Also, measured 3 dB axial ratio was 18 MHz(0.9 %). On the other hand, measured radiation patterns were isoflux patterns and its measured gain was 5.31 dBi at E-plane $46^{\circ}$ in the y-axis pol.

Dielectric and Field-induced Strain Behaviors due to Excess PbO in Lead Yttrium Zirconate Stannate Titanate Ceramics (과잉 PbO에 의한 (Pb,Y) $(Zr,Sn,Ti)O_3$세라믹스의 유전 및 전기장유기변형 특성)

  • Yun, Gi-Hyeon;Kim, Jeong-Hui;Gang, Dong-Heon
    • Korean Journal of Materials Research
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    • v.10 no.1
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    • pp.34-40
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    • 2000
  • The $Pb_{0.94}Y_{0.04}[(Zr_{0.6}Sn_{0.4})_{0.915}Ti_{0.085}]O_3$ ceramics which corresponded to the antiferroelectric-ferroelectric phase boundary composition were prepared for digital-type-piezoelectric/electrostrictive device application. Their dielectric, field-induced polarization (P) and strain (X) behaviors were studied with variations in sintering condition and excess PbO content. The orthorhombic structure of specimens was hardly affected either by excess PbO addition or sintering temperature. With increasing excess PbO content, grains tended to be smaller and rounded ones, and the optimum sintering temperature was lowered. Excess PbO addition stabilized the antiferroelectric phase of the specimen effectively, which was confirmed by P-E and X-E analyses. Also the digital-type-strain character was found to be enhanced despite of slight increase in phase transition (AFE-FE) field and electrical resistivity, and decrease in maximum strain. These results were explained in terms of possible lattice defects and domain wall motion.

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The Study on the Marek(말액) (말액에 관한 연구)

  • Kang Soon-Che;Jeon Hyun-Sil
    • Journal of the Korean Society of Costume
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    • v.55 no.5 s.95
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    • pp.78-86
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    • 2005
  • Marek(말액) is the headgear, which is a form of hempen hoods[Geon(건)] and the origin of it is Pa(파) of band form. A history book of an old Chinese country Post-Han $\ll$ History of HouHan (후한서)$\gg$ had recorded that a soldier wore a red band around his head that was called Pa(파). In the Han dynasty(한대), Pa had been transformed into Chaek(책) or a kind of a hemp rap(건) while e headgear had still remained as the band form and called Marek from e Tang era(당). The literatures of the Tang era had referred the red Marek of soldiers, and other literatures of the later period had recorded that of the previous headgears of the band form were related with Marek. Since the Tang era, white or yellow Marek except red one fer soldiers had been were by soldiers, musicians, dancers and singers in Yuan(원) and Ming(명) of China. The colors was recorded in red on documents mostly, this red implicated soldiers for symbol of terror. This fart was documented in an old history book $\ll$The history of 25 Eras(이십오사)$\gg$, On the other side, a wall painting in Princess Jeonghyo(정효공주)'s tomb of the Parhae(발해) period described the portraits of twelve persons, and among them, two Siwui(시위) put on the red Marek. Quoted from the record of a history book of the Tang era system , a history book of Three Kingdoms(삼국시대) of ancient Korea $\ll$Samguksaki(삼국사기)$\gg$ described that four dancers of Kogryo(고구려) wore Marek on their heads with the costumes of Koguryo, one of those Kingdoms. In consideration that the book of $\ll$Tongjun$\gg$ was the literature of the Tang era so that Marek mentioned in this book was followed by their name, the Marek of Koguryo dancers shown in the history book $\ll$Samguksaki(삼국사기)$\gg$ might be a kind of Koguryo style hemp cap[Geon(건)]. The Marek of Parhae had succeeded to the headgear of Koguryo and the identity was on Koguryo.

Desperately Seeking an Icon (with 8 Legs): (애니메이션 창세기 첫 페이지의 오류, 그 기원과 수정)

  • Nah, Ho-Won
    • Cartoon and Animation Studies
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    • s.45
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    • pp.417-434
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    • 2016
  • The wall painting of Altamira cave "eight-legged wild boar" is often presented as a typical example of long-held desire of humanity for expressing movement. However, the eight legs are the product of so-called "double layer", of two paintings painted in different periods. Nonetheless, the explanation of Altamira cave paintings linking with the origin of animation is constantly reproduced without any particular doubt, verification or citation of sources. The fact of associating eight legs with movement is irrelevant to visual perception transcending time. This should be considered a movement expression code invented in a particular period of time. Sequential photography tried in the late 19th century, in particular, chronography of $\acute{E}tienne$-Jules Marey plays a crucial role in this. Marey's photography of which a series of sequence movements are overlapped in one frame and printed was reflected in painting works of artists including Duchamp and Balla in the early 20th century and formed as movement expression code. Animation manuals started to emerge from that period of time introduced the images of Marey's chronophotography as a way of analyzing and embodying the movement. In sum, the act of considering Altamira cave paintings of eight-legged wild boar as an expression of movement is an error intending to look at the past through today's visual code.

Comparison of Quantitative Endotoxin against 5 Species of Enterobacteriaceae (장내세균 5종의 Endotoxin 정량 비교)

  • Kwon, Pil Seung
    • Korean Journal of Clinical Laboratory Science
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    • v.48 no.2
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    • pp.124-129
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    • 2016
  • Endotoxin, also known as lipopolysaccharide (LPS) produced by the cell wall of gram negative bacteria can be present in any liquid or on any biomaterial. Endotoxin in blood can cause fever and inflammation. In this study, we compared bacterial endotoxin using Escherichia coli O157:H7, Klebsiella oxytoca, Salmonella Typhi, Shigella sonnei and Morganella morganii. Bacteria were cultured for use in the experiment, and diluted to $1.5{\times}10^8CFU/mL$. A check marked sensitivity confirmatory test of the Limulus amebocyte lysate (LAL) reagent was performed to examine the validity. The end point reaction to each bacteria sample was confirmed with 10 fold dilution and then the final reaction end point was confirmed by 2 fold dilution between the dilution step and the upper dilution step. According to the results, in detection of endotoxins in more than 0.015 EU/mL, E. coli O157 was 75~37.5 CFU/mL, K. oxytoca 37.5~18.75 CFU/mL, M. morganii and S. Typhi 3.75~1.875 CFU/mL, and S. sonnei 7.5~3.75 CFU/mL. The resulting value was finally ensured by a confirmation test for the inhibitory factor. Based on this study, conduct of further research on bacterial endotoxin is encouraged.

Method development for quantitative analysis of naturally occurring radioactive nuclides in building materials (실내 건축자재 중 천연방사성핵종의 정량분석법 연구)

  • Lim, Jong-Myoung;Lee, Hoon;Kim, Chang-Jong;Jang, Mee;Park, Ji-Young;Chung, Kun Ho
    • Analytical Science and Technology
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    • v.30 no.5
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    • pp.252-261
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    • 2017
  • Naturally occurring radioactive materials (NORMs) increase radiation exposure to the public as these materials are concentrated through artificial manufacturing processes by human activities. This study focuses on the development of a method for the quantitative analysis of $^{232}Th$, $^{235}U$, and $^{238}U$ in building materials. The accuracy and precision of inductively coupled plasma mass spectrometry (ICP-MS) for determination of digestion processes was evaluated for certified reference materials (CRMs) digested using various mixed acid (e.g., aqua regia, hydrofluoric acid, and perchloric acid) digestions and a $LiBO_2$ fusion method. The method validation results reveal that a $LiBO_2$ fusion and $Fe(OH)_3$ co-precipitation should be applied as the optimal sample digestion process for the quantitative analysis of radionuclides in building materials. The radioactivity of $^{232}Th$, $^{235}U$, and $^{238}U$ in a total of 51 building material (e.g., board, brick, cement, paint, tile, and wall paper) samples was quantitatively analyzed using an established process. Finally, the values of $^{238}U$ and $^{232}Th$ radioactivity were comprehensively compared with those from the indirect method using ${\gamma}$-spectrometry.

Preparation of Wall Paper Coated with Modified TiO2 and Their Photocatalytic Effects for Removal of NO in Air (변조된 TiO2 광촉매를 이용한 벽지제조와 대기 중의 NO 제거 효과)

  • Kwon, Tae-Ri;Roo, Wan-Ho;Lee, Chul-Woo;Lee, Won-Mook
    • Korean Chemical Engineering Research
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    • v.43 no.1
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    • pp.1-8
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    • 2005
  • In this study, $TiO_2$ powders were prepared by hydro-thermal synthesis with titanium tetra isopropoxide. The prepared $TiO_2$ and the commercial $TiO_2$(P-25, Degussa) were by impregnating $H_2PtCl_6$ solution or the leached solution from the waste catalytic converter of automobile. Modified photocatalysts were analyzed by ICP-AES, UV-DRS, XRD, SEM. And band-gap energy of modified photo-catalyst was found to decreased to 1.76eV and basic structure was changed upon modification by leached solution. Modified photocatalysts were coated on the wallpaper after using mixed solution with adhesive materials(PVC). And then to know the modified photo catalysts tested the reactivity and quantum efficiency in the mixed gas with NO as reactants in the photo catalytic reactor. In the gas phase, photo-catalytic activity of NO was the highest for modified P-25 catalysts(P-25(w)) that P-25(w) was impregnated by leached solution of wasted catalytic converter.