• Journal of the Society of Cosmetic Scientists of Korea
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• v.49 no.1
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• pp.59-65
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• 2023

We validated the physiological activity of Syzygium claviflorum (Roxb.) Wall. ex A.M. Cowan & Cowan (S. claviflorum) extracts (leaves, stems, fruits, and flowers) as a cosmetic ingredient. Firstly, S. claviflorum extracts removed over 80% of free radicals at various concentrations in antioxidant experiments using the DPPH and ABTS assay. In cytotoxicity experiments using human epidermal keratinocytes, S. claviflorum extracts showed low cytotoxicity. In addition, S. claviflorum extracts significantly increased the expression of keratin (KRT)1, KRT2, KRT9, KRT10, which are differentiation markers of keratinocytes, as well as genes involved in the maintenance of skin barrier function, including involucrin (IVL), loricrin (LOR), filaggrin (FLG), and claudin1 (CLDN1). In particular, the expression of FLG protein, inhibited by interleukin (IL)-4/IL-13 in atopic dermatitis, was restored by S. claviflorum extracts in in vitro experiments. Therefore, S. claviflorum extracts with excellent antioxidant efficacy and skin barrier improvement function will be useful materials for the development of future atopic dermatitis treatments and cosmetics.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.6
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• pp.573-582
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• 2021

In this study, a series of processes for evaluating the effective protection against barriers that should be equipped in institutions that perform reliability tests on high-risk ammunition, such as high-explosive ammunition, were introduced. The impact that high-explosive bombs can have on personnel includes damage to the eardrum and lungs caused by explosion overpressure and penetrating wounds that can be received by fragments generated simultaneously with the explosion. Therefore, a high-explosive with COMP B explosives as its contents were set up, and an explosion protection theory investigation to calculate the degree of damage, numerical calculations and simulations were performed to verify the protection power. A numerical calculation revealed the maximum explosion overpressure on the protective wall when the high-explosive exploded and the penetration force of the fragment against a 50 mm-thick protective wall to be 77.74 kPa and 41.34 mm, respectively. In the simulation verification using AUTODYN, the maximum explosion overpressures affecting the firewall and personnel were 56.68 kPa and 18.175 kPa, respectively, and the penetration of fragments was 35.56 mm. This figure is lower than the human damage limit, and it was judged that the protective power of the barrier would be effective.

• Journal of Soil and Groundwater Environment
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• v.6 no.3
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• pp.53-59
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• 2001

There is a lot of method to manage the insanitary landfill but vertical cutoff walls have been widespreadly used and were installed into the subsurface to act as a barrier to horizontal groundwater flow, The stabilized material such as specialized cement or mixed soil with additives has been generally applied for the materials of the deep soil mixing barrier in korea. The amount of the stabilized material is dependent on the field conditions, because the mixing ratio of the material and the field soil should achieve a requirement in the coefficient of permeability, lower than 1.0$\times$$10^{7}$cm/sec. This study determined the quantity and optimized function ratio of the stabilized material in the formation process of the mixed barrier that was added with stabilized material on the field soil classified into SW-SC under USCS (Unified Soil Classification System). After that the fly ash and lime were selected as an additives an that could improve the function of the stabilized material and then the method to improve the functional progress in the usage of putting into the stabilized material as an appropriate ratio was studied and reviewed. The author used the flexible-wall permeameter for measuring the permeability and unconfined compressive strength tester for compressive strength, and in the view of environmental engineering the absorption test of heavy metals and leaching test regulated by Korean Waste Management Act were performed. As the results, the suitable mixing ratio of the stabilized material in the deep soil mixing barrier was determined as 13 percent. To make workability easy, the ratio of stabilized material and water was proven to be 1 : 1.5. With the results, the range of the portion of the additives(fly ash : lime= 70 : 30) was proven to be 20-40% for improving the function of the stabilized material, lowering of permeability. In heavy metal absorption assessment of the mixing barrier system with the additives, the result of heavy metal absorption was proved to be almost same with the case of the original stabilized material; high removal efficiency of heavy metals. In addition, the leaching concentration of heavy metals from the leaching test for the environmental hazard assessment showed lower than the regulated criteria.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.20 no.9
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• pp.2894-2900
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• 1996

The stream generator tubes represent an integral part of a major barrier against the fission product release to the environment. So, the rupture of these tubes could permit flow of reactor coolant into the secondary system and injure the safety of reactor coolant system. Therefore, if the crack was detected during In-Service Inspection of tubes the cracked tube should be evaluated by the pulgging criteria and plugged or not. In this study, the fracture mechanics evaluation is carried out on the thru-wall axial crack due to Primary Water Stress Corrosion Cracking in the roll transition aone of steam generator tube to help the assurence the integrity of tubes and estabilish the plugging criteria. Due to the Inconel which is used as tube material is more ductile than others, the plastic instability repture theory was used to calculate the critical and allowable crack length. Based on Leak Before Break concept the leak rate for the critical crack length and the allowable leak rate are compared and the safety of tubes was given.

• Journal of Korean Society of Environmental Engineers
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• v.37 no.2
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• pp.120-125
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• 2015

With rapid urbanization, the volume of traffic in urban area has been significantly increased. This in turn led to problem which can be described as Road Traffic Noise. Currently, to alleviate the road traffic noise damage, a demand for installation of soundproofing walls is rising. Among different shapes of soundproof walls being installed, the reflection-type acoustical insulation panel is highly drawing attentions of residents due to the fact that it does not obstruct their field of vision in contrast with the opaque acoustical insulation panel. On the other hand, improving the soundproofing wall of the reflection-type acoustical insulation barrier panel needs to be focused on since it has a possibility to cause a secondary damage by reflected sounds. Therefore, in this research, study has been carried out to improve the forms in order to minimize travelling of reflected sounds through changing the frontal surface shape and geometrical shape of the reflection-type soundproofing panel. A result from comparison between the normal reflection-type soundproofing panel and the improved soundproofing panel, with reduction effects in the noise reflection, showed that the curved type of soundproofing panel has an impact on reducing the noise up to 1.5 dB. Furthermore, from the research conducted, it appears that the increase and decrease in the reflected sounds can be changeable depending on various design factors. Thus, it turns out that the study shows a potential possibility to develop a reduction technology of the reflected sounds pertaining to overall condition on the soundproofing walls.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.35-35
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• 2017

How do plants take up water from soils especially when water is scarce in soils? Plants have a strategy to respond to water deficit to manage water necessary for their survival and growth. Plants regulate water transport inside them. Water flows inside the plant via (i) apoplastic pathway including xylem vessel and cell wall and (ii) cell-to-cell pathway including water channels sitting in cell membrane (aquaporins). Water transport across the root and leaf is explained by a composite transport model including those pathways. Modification of the components in those pathways to change their hydraulic conductivity can regulate water uptake and management. Apoplastic barrier is modified by producing Casparian band and suberin lamellae. These structures contain suberin known to be hydrophobic. Barley roots with more suberin content from the apoplast showed lower root hydraulic conductivity. Root hydraulic conductivity was measured by a root pressure probe. Plant root builds apoplastic barrier to prevent water loss into dry soil. Water transport in plant is also regulated in the cell-to-cell pathway via aquaporin, which has received a great attention after its discovery in early 1990s. Aquaporins in plants are known to open or close to regulate water transport in response to biotic and/or abiotic stresses including water deficit. Aquaporins in a corn leaf were opened by illumination in the beginning, however, closed in response to the following leaf water potential decrease. The evidence was provided by cell hydraulic conductivity measurement using a cell pressure probe. Changing the hydraulic conductivity of plant organ such as root and leaf has an impact not only on the speed of water transport across the plant but also on the water potential inside the plant, which means plant water uptake pattern from soil could be differentiated. This was demonstrated by a computer simulation with 3-D root structure having root hydraulic conductivity information and soil. The model study indicated that the root hydraulic conductivity plays an important role to determine the water uptake from soil with suboptimal water, although soil hydraulic conductivity also interplayed.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2005.04a
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• pp.202-210
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• 2005

In this study, the fly ash was employed as a possible alternative to the bentonite for its high sorption capacity against cationic heavy metal. To consider the constituents of barrier possibly used, the specimens were mixed with different material contents (fly ash : weathered soil : bentonite), then sorption test was performed. Also the specimens were molded on the wet side of optimum moisture contents like mixing ratio of sorption test and their hydraulic conductivities were measured in flexible-wall permeameters. And to confirm the effect of dissolved cations, the hydraulic conductivity tests were repeated by converting the permeant liquids from water to $Cd^{2+}$ solution. Finally, the Cd-concentration at the effluent was analyzed for 500hrs to compare the effectiveness of each specimen in contaminant retardation. Test results showed that the more the ratio of fly ash increase, the more Kd value increase, and the hydraulic conductivity of weathered soil/bentonite (95:5) mixture was the lowest $(2.9*10^{-8}cm/sec)$, and specimens made of fly ash and fly ash/weathered soil mixtures showed similar hydraulic conductivity. Although the permeant liquid was changed from water to $Cd^{2+}$ solution, the hydraulic conductivity of all specimens except for weathered soil maintained similarly like before. Consequently, the initial breakthrough point of Cd in weathered soil specimen was observed at about 5hrs after the test started while that of fly ash specimens was not observed during the whole test period of 500hrs. The results implied that fly ash had a sufficient retardation capacity against contaminant transport possibly by its high sorption capacity although it showed little effect on the reduction of hydraulic conductivity. Based on the test results, it could be concluded that the fly ash can be possibly used as a suitable barrier material in containment system to attenuate the contaminant transport for its high retardation capacity and for the low cost.

• Applied Microscopy
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• v.29 no.1
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• pp.11-23
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• 1999

Ultrastructure of the ependymal cells of X-irradiated rats on their head were studied. Rats weighing $200\sim250gm$ were X-irradiated on their head and neck areas. Total exposures were 3,000 rads or 6,000 rads depending on experimental groups. And irradiated rats were sacrificed on 6 hours, 2 days and 6 days following the radiation exposures. Animals were perfused through the heart with 1% glutaraldehyde-1% paraformaldehyde solution, under ether-anesthesia. The tissues from the wall of lateral ventricles were fixed in the 2% osmium tetroxide solution. The results observed with electron microscope were as follow: 1. In 6 hours group, many ependymal cells were swelled, luminal portions of cytoplasms of some cells protruded into the ventricular lumen, and many cilia were lost or irregularly altered. 2. In 2 days group, ependymal cells were swelled more severely and subependymal edema were pronounced. 3. Protruded cytoplasm contained usually basal bodies of cilia, groups of mitochondria, endoplasmic reticula , etc. 4. Following X-irradiations, some protruded masses contained neural elements including the axon terminals with dense core vesicles. Axons and axon terminals were also found in the enlarged intercellular spaces among ependymal cells. From the above results, the heavy irradiation on the head area of the rat induced alteration of the ependymal cells lining the lateral ventricle. Hence the ependymal functions of selective barrier, protective barrier, and metabolic barrier could be altered following X-irradiation on the head.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.24 no.3
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• pp.343-351
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• 2011

Nuclear containment building is the last barrier for being secure from any nuclear power plant accident. Therefore, it is very important to understand the ultimate capacity of nuclear containment building to loads associated with severe accidents. LOCA (loss of coolant accident) is considered as the basic accidental load and CANDU-type containment building is considered as a target structure in order to conduct the numerical analysis for the structural safety of a containment building. The CANDU-type containment building is a prestressed concrete shell structure which has the dome and the cylindrical wall and is reinforced with bonded tendons. In this paper, the evaluation of ultimate internal pressure capacity was carried out by nonlinear analysis of a prestressed concrete containment building using 3-dimensional structural analysis system.

• Childhood Kidney Diseases
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• v.19 no.2
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• pp.65-70
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• 2015

It is well known that proteins present in the primary urine are reabsorbed in the renal proximal tubules, and that this reabsorption is mediated via the megalin-cubilin complex and the neonatal $Fc{\gamma}$ receptor. However, the reabsorption is also thought to be influenced by an electrostatic interaction between protein molecules and the microvilli of the renal proximal tubules. By analyzing the charge diversity of urinary IgG, we showed that this reabsorption process occurs in a cationic charge-preferential manner. The charge-selective molecular sieving function of the glomerular capillary walls has long been a target of research since Brenner et al. demonstrated the existence of this function by a differential clearance study by using the anionic dextran sulfate polymer. However, conclusive evidence was not obtained when the study was performed using differential clearance of serum proteins. We noted that immunoglobulin (Ig) A and IgG have similar molecular sizes but distinct molecular isoelectric points. Therefore, we studied the differential clearance of these serum proteins (clearance IgA/clearance IgG) in podocyte diseases and glomerulonephritis. In addition, we studied this differential clearance in patients with Dent disease rather than in normal subjects because the glomerular sieving function is considered to be normal in subjects with Dent disease. Our results clearly showed that the charge-selective barrier is operational in Dent disease, impaired in podocyte disease, and lacking in glomerulonephritis.