• Asian-Australasian Journal of Animal Sciences
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• v.24 no.2
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• pp.258-263
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• 2011

This experiment was conducted to evaluate the effects of dietary wild-ginseng adventitious root meal (WGM) on growth performance, blood profiles, relative organ weight and meat quality of broiler chickens. A total of 480, 2-day-old male broiler chicks (BW = $42.8{\pm}1.38\;g$) were randomly allocated to 1 of 4 dietary treatments (6 cages with 20 broilers per cage). Dietary treatments were: i) CON (basal diet), ii) WGM0.1 (basal diet+0.1% WGM), iii) WGM0.2 (basal diet+0.2% WGM) and iv) WGM0.3 (basal diet+ 0.3% WGM). Birds fed WGM0.3 diet (p<0.05) had a higher feed intake (FI) than those fed the CON diet during weeks 1 to 3. During weeks 3 to 5, dietary WGM0.1 treatment led to a higher (p<0.05) BW gain (BWG) and feed intake (FI) compared with the CON and WGM0.3 treatments. Overall, birds fed WGM0.1 improved BWG and FI compared with those fed the CON treatment. A greater lymphocyte count was observed (p<0.05) in WGM0.2 and WGM0.3 treatments compared with the CON treatment; dietary WGM decreased (p<0.05) the total cholesterol concentration compared with the CON group. The inclusion of WGM increased the relative weight of spleen and bursa of fabricius (p<0.05) compared with CON, while less abdominal fat was observed in the WGM0.3 treatment (p<0.05) compared with CON. The 2-thiobarbituric acid reactive substances (TBARS) of breast muscle were decreased (p<0.05) by WGM supplementation. Overall, our results indicated that the use of WGM at the 0.1% level could enhance growth performance in broilers. The supplementation of WGM could induce a decreased TBARS, abdominal fat and serum cholesterol in broiler chickens.

• Journal of Animal Science and Technology
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• v.45 no.6
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• pp.987-996
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• 2003

This study was conducted to determine the effects of the artificial culture medium of wild-ginsengs on in vitro fermentation characteristics. NH$_3$-N concentration was showed the highest in 3% WGM treatment among all treatments and control. In addition, microbial protein synthesis was significantly different in all treatments throughout the incubation time, and WGM 3% treatment was the highest at the 9 h incubation(P〈0.05). Protozoa numbers within rumen were decreased in all WGM treatments at 9 h incubation time, whereas WGM 3% treatment was always decreased throughout the incubation(P〈0.05). NDF and ADF digestibility were proportionally increased as the incubation time in both control and treatments. NDF digestibility showed no significantly difference between control and the 3% treatment, and ADF digestibility was similar in all. Total volatile fatty acid(VFA) concentrations of WGM treatments without 5% were significantly higher than control (P〈0.05). No differences were observed in total VFA, acetate, propionate and butyrate concentration among the WGM treatments. Acetate/Propionate ratio of WGM treatments was higher than control after 12 h incubation(P〈0.05). As a result of the artificial culture medium of wild-ginseng on rumen fermentation characteristics in vitro, microbial protein synthesis of WGM treatment was higher than control, and WGM 3% was the highest in all treatments(P〈0.05). The effect of saponin in artificial culture medium of wild-ginseng tended to decrease NH$_3$-N concentration, while it increases the microbial synthesis in early incubation. Therefore, artificial cultures medium of wild-ginseng can increase utilization of feed by microbial and anti-protozoal effects of saponin, which may enhance microbial synthesis capacity in early fermentation period in rumen.

• Journal of Applied Biological Chemistry
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• v.61 no.4
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• pp.341-349
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• 2018

The aim of this study was to evaluate autophagy-enhancing and neuroprotective effects of Wonji-Gobon mixture (WGM), a traditional Chinese prescription medication, in Parkinson's disease (PD) mouse models. Our investigation found that WGM increased the expression of both Beclin1 and LC3b-II proteins as measured with western blot in the BV2 cell line; both proteins play a role in autophagy. WGM also increased the autophagy expression as measured by fluorescence-activated cell-sorting analysis in the BV2 cell line. In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced PD models, WGM significantly increased the amount of dopamine in a striatum-substantia nigra suspension, produced notable results in the forced swim test, and increased serotonin as measured by high-performance liquid chromatography analysis; these results are indicative of neuroprotective effects. In summary, our findings indicate that WGM treatment has neuroprotective effects that are partially mediated by autophagy enhancement.

• Fisheries and Aquatic Sciences
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• v.26 no.2
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• pp.87-96
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• 2023

This study was designed to determine the apparent digestibility coefficients of soybean meal, soy protein concentrate (SPC), soy protein isolate (SPI), rapeseed meal (RSM), pea protein concentrate (PPC), wheat gluten meal (WGM) and wheat flour (WF) for olive flounder, Paralichthys olivaceus. A reference diet (RF) was formulated to meet the nutrient requirements of olive flounder with 1% chromic oxide (Cr₂O₃) as an inert indicator. Test diets were prepared to contain 70% RF and 30% of the test ingredient. Olive flounder, averaging 150 ± 8.0 g, was cultured in 400-L fiberglass tanks at a density of 25 fish per tank. Fecal collection columns were attached to each tank. Fecal samples were obtained from triplicate groups of fish for 4 weeks. Dry matter digestibility of SPC (75%) and WGM (76%) were significantly higher than the other test ingredients. Protein digestibility of SPC (85%), PPC (88%) and WGM (89%) were significantly higher than the other test ingredients, and protein digestibility of RSM (77%) and WF (76%) was lower than the other ingredients tested. Lipid digestibility of SPC (72%) and SPI (69%) were significantly higher than the other test ingredients. Energy digestibility of SPC (85%) and WGM (82%) were significantly higher than that of others tested ingredients. The availability of amino acids in WGM was generally higher than in other plant-feed ingredients. Therefore, SPC and WGM were seems to be efficient as potential protein sources for olive flounder compared to other tested ingredients. Overall, findings of the current study may assist in more efficient and economical formulation of diets using plant feed ingredients for olive flounder.

• Proceedings of the Optical Society of Korea Conference
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• 2006.07a
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• pp.13-14
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• 2006

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.133.1-133.1
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• 2014

이 발표에서 우리는 수백 나노미터 크기인 두 개의 나노 금속 원반 또는 나노 블록이 백 나노미터 이하의 간격으로 결합된 초미세 이중 금속 플라즈몬 광공진기를 제안하고 그 응용을 살펴본다. 원반구조 경우, 반지름이 476 nm인 나노원반 두 개가 100 nm 두께의 유전체 원반의 양쪽에 위치하여 1550 nm 공진파장을 가진 표면 플라즈몬 whispering-gallery-mode (WGM)을 유전체 내에 형성한다. 유전체의 두께를 일정하게 유지할 경우, WGM의 공진파장은 원반의 반지름에 따라 줄어든다. 반면, 반지름이 일정할 때에는 두 금속 원반 사이의 유전체 두께가 줄어듦에 따라 두 금속 원반 사이에 작용하는 표면 플라즈몬의 결합이 강해져서 공진파장이 길어진다. 따라서, 일반적으로 공진기의 크기가 줄어듦에 따라 공진파장이 짧아지는 것과 달리, 제안된 원반구조에서 발생하는 WGM는 원반의 반지름과 유전체의 두께를 함께 줄여도 공진파장이 동일하게 유지되는 차별화된 특성을 가지고 있다. 최종적으로 같은 공진파장을 가지는 WGM를 반지름 88 m, 유전체 두께 10 nm의 공진기에서도 여기시킬 수 있음으로, 모드부피(V)를 1/160으로 줄일 수 있다. 이에 비해, 공진모드의 품위값(Q)은 증가된 금속의 흡수손실에 의해 1/3정도 줄어듦으로써, 공진기와 물질의 상호작용 정도를 보여주는 Q/V값은 크기가 줄어든 공진기에서 오히려 50배 가량 증가함을 확인할 수 있다. 이 같은 초미세 플라즈몬 공진기는 매우 작은 굴절율 센서로서 응용을 가지고 있으며, 1160 nm/(단위 굴절율 변화)의 높은 민감도를 보인다. 한편, $200{\times}150{\times}100nm3$의 크기를 가진 두 개의 금속 나노블록이 10 nm의 공기 간격을 가지고 결합된 나노 공진기는, 공기 간격 내에 강하게 집적된 838 nm의 공진파장을 가진 플라즈몬 공진기 모드를 여기시킨다. 제안된 공진모드는 공기간격이 줄어듦에 따라 공진파장이 급격하게 증가하는 특성을 가지므로 옹스토롬 정도의 분해능을 가진 두께 변화 센서로 응용할 수 있다. 예를 들어, 공기간격 2 nm에서는 1A 두께 변화에 대해 공진파장 변화는 약 40 nm로 매우 민감하게 변화한다.

• Proceedings of the Optical Society of Korea Conference
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• 2000.08a
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• pp.82-83
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• 2000

굴절율이 외부보다 큰 실린더 (cylinder)나 스피어 (sphere)는 경계면에서의 전반사에 의해 손실이 매우 적은 high-Q 공진기가 될 수 있음이 잘 알려져 있다. 크기가 수 십 $mu extrm{m}$ 되는 실린더나 스피어에서의 공명모드는 편광(TM, TE), 모드 수 (mode number) n, 모드 순서 (mode order) l에 의해 정의되고 WGM (whispering gallery mode)라고도 불리워진다$^{(1)}$ . 모드 수n 이 클수록 모드 순서 l이 작을수록 공명모드의 Q 값은 큰 경향을 가진다. 액체 방울이나 액체 제트와 같이 열적 섭동에 민감한 마이크로 공진기 (micro-cavity)의 경우 Q값이 $10^{7}$ 정도로 제약되나, 실리카 마이크로 스피어 (micro-sphere)와 같은 고체 구에서 측정된 Q값은 약 $101^{10}$ 정도로 손실이 매우 적은 공진기가 될 수 있다$^{(2)}$ . 이와 같은 마이크로 공진기 특성을 이용하여 다양한 형태의 마이크로 공진기 레이저 대한 연구가 진행되어 왔다. 색소가 첨가된 고체구, 액체 방울, 액체 제트 등에서 기본적인 실험이 이루어졌고 반도체마이크로 스피어 구조에서 WGM 레이저$^{(3)}$ , polymer disc laser$^{(4)}$ , 광양자테 (photonic quantum ring)$^{(5)}$ 특성 연구 등이 실용가능성을 목표로 진행되고 있다. (중략)

• Korean Journal of Optics and Photonics
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• v.29 no.3
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• pp.104-109
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• 2018

We explain the basic principle of transformation optics, and introduce several design techniques for transformation cavities that can maintain the characteristics of whispering gallery modes (WGMs) even if the cavity is strongly deformed from a circular shape. As a method of obtaining various transformation cavities under a specific conformal mapping, we suggest a method of parallel movement of the initial cavity domain, and a method of rotating the ellipse as a cavity domain. The internal wave pattern and the far-field output characteristics of several designed resonant modes are numerically calculated. From these results, it is confirmed that a variety of GRIN resonators are possible for a given conformal coordinate transformation.

• Proceedings of the Optical Society of Korea Conference
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• 2003.07a
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• pp.90-91
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• 2003

정사각형 (sqaure) 구조 미소공진기는 Q값이 큰 4-bounce whispering gallery mode (WGM)가 존재 할 수 있고, 외부 도파로와 표면감쇠파 결합을 통해 상호작용할 때, 결합 길이가 매우 길어질 수 있어, 광통신용 Add／Drop Filter, 광집적회로 등의 저문턱 미소공진기 레이저 등의 광소자 분야에 적용하려는 연구가 최근 진행되고 있다. 그러나 단일 경계면을 갖는 사각 공진기는 공간 모드가 매우 많은 multimode 특성을 띄기 때문에 응용에 있어 단점이 된다. (중략)

• Proceedings of the Optical Society of Korea Conference
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• 2000.08a
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• pp.84-85
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• 2000

굴절률이 외부보다 큰 원통(cylinder)이나 구(sphere)는 경계면에서의 빛의 전반사(total internal reflection)에 의해 손실이 매우 적은 high-Q 공진기가 될 수 있음이 잘 알려져 있다. 이때 발진되는 공명모드를 '속삭이는 회랑 모드(whispering gallery mode: WGM)'라고 하며, 색소가 첨가된 고체 구, 액체 방울, 액체 제트 등의 미소 공진기나 반도체 microdisk 등에서 구현되었다. 이러한 미소공진기는 일반적으로 완전한 구나 실린더의 형태로 만들어지는데, 이 경우 공진 모드를 analytic 하게 구할 수 있고 기하 광학적으로 비교적 간단히 이해할 수 있다. 하지만 최근 Nockel 등에 의해 공진기에 변형을 가한 경우 여러 가지 재미있는 현상이 일어날 수 있다는 것이 밝혀졌다$^{(1, 2)}$ (중략)